Research ArticleArticle
The Noradrenergic Component in Tapentadol Action Counteracts μ-Opioid Receptor–Mediated Adverse Effects on Adult Neurogenesis
Vasco Meneghini, Bruna Cuccurazzu, Valeria Bortolotto, Vera Ramazzotti, Federica Ubezio, Thomas M. Tzschentke, Pier Luigi Canonico and Mariagrazia Grilli
Molecular Pharmacology May 2014, 85 (5) 658-670; DOI: https://doi.org/10.1124/mol.113.091520
Vasco Meneghini
Laboratory of Neuroplasticity and Pain (V.M., B.C., V.B., V.R., F.U., M.G.) and Department of Pharmaceutical Sciences (V.M., B.C., V.B., V.R., F.U., P.L.C., M.G.), University of Eastern Piedmont Amedeo Avogadro, Novara, Italy; and Global Innovation, Department of Pain Pharmacology, Grünenthal GmbH, Aachen, Germany (T.M.T.)
Bruna Cuccurazzu
Laboratory of Neuroplasticity and Pain (V.M., B.C., V.B., V.R., F.U., M.G.) and Department of Pharmaceutical Sciences (V.M., B.C., V.B., V.R., F.U., P.L.C., M.G.), University of Eastern Piedmont Amedeo Avogadro, Novara, Italy; and Global Innovation, Department of Pain Pharmacology, Grünenthal GmbH, Aachen, Germany (T.M.T.)
Valeria Bortolotto
Laboratory of Neuroplasticity and Pain (V.M., B.C., V.B., V.R., F.U., M.G.) and Department of Pharmaceutical Sciences (V.M., B.C., V.B., V.R., F.U., P.L.C., M.G.), University of Eastern Piedmont Amedeo Avogadro, Novara, Italy; and Global Innovation, Department of Pain Pharmacology, Grünenthal GmbH, Aachen, Germany (T.M.T.)
Vera Ramazzotti
Laboratory of Neuroplasticity and Pain (V.M., B.C., V.B., V.R., F.U., M.G.) and Department of Pharmaceutical Sciences (V.M., B.C., V.B., V.R., F.U., P.L.C., M.G.), University of Eastern Piedmont Amedeo Avogadro, Novara, Italy; and Global Innovation, Department of Pain Pharmacology, Grünenthal GmbH, Aachen, Germany (T.M.T.)
Federica Ubezio
Laboratory of Neuroplasticity and Pain (V.M., B.C., V.B., V.R., F.U., M.G.) and Department of Pharmaceutical Sciences (V.M., B.C., V.B., V.R., F.U., P.L.C., M.G.), University of Eastern Piedmont Amedeo Avogadro, Novara, Italy; and Global Innovation, Department of Pain Pharmacology, Grünenthal GmbH, Aachen, Germany (T.M.T.)
Thomas M. Tzschentke
Laboratory of Neuroplasticity and Pain (V.M., B.C., V.B., V.R., F.U., M.G.) and Department of Pharmaceutical Sciences (V.M., B.C., V.B., V.R., F.U., P.L.C., M.G.), University of Eastern Piedmont Amedeo Avogadro, Novara, Italy; and Global Innovation, Department of Pain Pharmacology, Grünenthal GmbH, Aachen, Germany (T.M.T.)
Pier Luigi Canonico
Laboratory of Neuroplasticity and Pain (V.M., B.C., V.B., V.R., F.U., M.G.) and Department of Pharmaceutical Sciences (V.M., B.C., V.B., V.R., F.U., P.L.C., M.G.), University of Eastern Piedmont Amedeo Avogadro, Novara, Italy; and Global Innovation, Department of Pain Pharmacology, Grünenthal GmbH, Aachen, Germany (T.M.T.)
Mariagrazia Grilli
Laboratory of Neuroplasticity and Pain (V.M., B.C., V.B., V.R., F.U., M.G.) and Department of Pharmaceutical Sciences (V.M., B.C., V.B., V.R., F.U., P.L.C., M.G.), University of Eastern Piedmont Amedeo Avogadro, Novara, Italy; and Global Innovation, Department of Pain Pharmacology, Grünenthal GmbH, Aachen, Germany (T.M.T.)

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Research ArticleArticle
The Novel Analgesic Tapentadol Does Not Impair Adult Neurogenesis
Vasco Meneghini, Bruna Cuccurazzu, Valeria Bortolotto, Vera Ramazzotti, Federica Ubezio, Thomas M. Tzschentke, Pier Luigi Canonico and Mariagrazia Grilli
Molecular Pharmacology May 1, 2014, 85 (5) 658-670; DOI: https://doi.org/10.1124/mol.113.091520
Research ArticleArticle
The Novel Analgesic Tapentadol Does Not Impair Adult Neurogenesis
Vasco Meneghini, Bruna Cuccurazzu, Valeria Bortolotto, Vera Ramazzotti, Federica Ubezio, Thomas M. Tzschentke, Pier Luigi Canonico and Mariagrazia Grilli
Molecular Pharmacology May 1, 2014, 85 (5) 658-670; DOI: https://doi.org/10.1124/mol.113.091520
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