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Research ArticleArticle

Kinetics of Drug Interaction with the Kv11.1 Potassium Channel

Adam P. Hill, Mark J. Perrin, Juliane Heide, Terence J. Campbell, Stefan A. Mann and Jamie I. Vandenberg
Molecular Pharmacology May 2014, 85 (5) 769-776; DOI: https://doi.org/10.1124/mol.114.091835
Adam P. Hill
Mark Cowley Lidwill Research Program in Cardiac Electrophysiology, Victor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia (A.P.H., J.H., T.J.C., S.A.M., J.I.V.); St. Vincent’s Clinical School, University of New South Wales, Darlinghurst, New South Wales, Australia (A.P.H., J.H., T.J.C., S.A.M., J.I.V.); and Barwon Health, Geelong, Victoria, Australia (M.J.P.)
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Mark J. Perrin
Mark Cowley Lidwill Research Program in Cardiac Electrophysiology, Victor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia (A.P.H., J.H., T.J.C., S.A.M., J.I.V.); St. Vincent’s Clinical School, University of New South Wales, Darlinghurst, New South Wales, Australia (A.P.H., J.H., T.J.C., S.A.M., J.I.V.); and Barwon Health, Geelong, Victoria, Australia (M.J.P.)
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Juliane Heide
Mark Cowley Lidwill Research Program in Cardiac Electrophysiology, Victor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia (A.P.H., J.H., T.J.C., S.A.M., J.I.V.); St. Vincent’s Clinical School, University of New South Wales, Darlinghurst, New South Wales, Australia (A.P.H., J.H., T.J.C., S.A.M., J.I.V.); and Barwon Health, Geelong, Victoria, Australia (M.J.P.)
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Terence J. Campbell
Mark Cowley Lidwill Research Program in Cardiac Electrophysiology, Victor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia (A.P.H., J.H., T.J.C., S.A.M., J.I.V.); St. Vincent’s Clinical School, University of New South Wales, Darlinghurst, New South Wales, Australia (A.P.H., J.H., T.J.C., S.A.M., J.I.V.); and Barwon Health, Geelong, Victoria, Australia (M.J.P.)
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Stefan A. Mann
Mark Cowley Lidwill Research Program in Cardiac Electrophysiology, Victor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia (A.P.H., J.H., T.J.C., S.A.M., J.I.V.); St. Vincent’s Clinical School, University of New South Wales, Darlinghurst, New South Wales, Australia (A.P.H., J.H., T.J.C., S.A.M., J.I.V.); and Barwon Health, Geelong, Victoria, Australia (M.J.P.)
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Jamie I. Vandenberg
Mark Cowley Lidwill Research Program in Cardiac Electrophysiology, Victor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia (A.P.H., J.H., T.J.C., S.A.M., J.I.V.); St. Vincent’s Clinical School, University of New South Wales, Darlinghurst, New South Wales, Australia (A.P.H., J.H., T.J.C., S.A.M., J.I.V.); and Barwon Health, Geelong, Victoria, Australia (M.J.P.)
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Article Information

vol. 85 no. 5 769-776
DOI 
https://doi.org/10.1124/mol.114.091835
PubMed 
24586056

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received January 16, 2014
  • Accepted February 28, 2014
  • Published online March 27, 2014.

Article Versions

  • Earlier version (February 28, 2014 - 11:00).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2014 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Adam P. Hill,
  2. Mark J. Perrin,
  3. Juliane Heide,
  4. Terence J. Campbell,
  5. Stefan A. Mann, and
  6. Jamie I. Vandenberg
  1. Mark Cowley Lidwill Research Program in Cardiac Electrophysiology, Victor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia (A.P.H., J.H., T.J.C., S.A.M., J.I.V.); St. Vincent’s Clinical School, University of New South Wales, Darlinghurst, New South Wales, Australia (A.P.H., J.H., T.J.C., S.A.M., J.I.V.); and Barwon Health, Geelong, Victoria, Australia (M.J.P.)
  1. Address correspondence to:
    Jamie I. Vandenberg, Victor Chang Cardiac Research Institute, 405 Liverpool Street, Darlinghurst, NSW 2010, Australia. E-mail: j.vandenberg{at}victorchang.edu.au
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Molecular Pharmacology: 85 (5)
Molecular Pharmacology
Vol. 85, Issue 5
1 May 2014
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Research ArticleArticle

Kinetics of Drug-Binding to Kv11.1

Adam P. Hill, Mark J. Perrin, Juliane Heide, Terence J. Campbell, Stefan A. Mann and Jamie I. Vandenberg
Molecular Pharmacology May 1, 2014, 85 (5) 769-776; DOI: https://doi.org/10.1124/mol.114.091835

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Research ArticleArticle

Kinetics of Drug-Binding to Kv11.1

Adam P. Hill, Mark J. Perrin, Juliane Heide, Terence J. Campbell, Stefan A. Mann and Jamie I. Vandenberg
Molecular Pharmacology May 1, 2014, 85 (5) 769-776; DOI: https://doi.org/10.1124/mol.114.091835
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