Research ArticleArticle
19-Substituted Benzoquinone Ansamycin Heat Shock Protein-90 Inhibitors: Biological Activity and Decreased Off-Target Toxicity
Chuan-Hsin Chang, Derek A. Drechsel, Russell R. A. Kitson, David Siegel, Qiang You, Donald S. Backos, Cynthia Ju, Christopher J. Moody and David Ross
Molecular Pharmacology June 2014, 85 (6) 849-857; DOI: https://doi.org/10.1124/mol.113.090654
Chuan-Hsin Chang
Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado (C.-H.C., D.A.D., D.S., Q.Y., D.S.B., C.J., D.R.); and School of Chemistry, University of Nottingham, Nottingham, United Kingdom (R.R.A.K., C.J.M.)
Derek A. Drechsel
Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado (C.-H.C., D.A.D., D.S., Q.Y., D.S.B., C.J., D.R.); and School of Chemistry, University of Nottingham, Nottingham, United Kingdom (R.R.A.K., C.J.M.)
Russell R. A. Kitson
Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado (C.-H.C., D.A.D., D.S., Q.Y., D.S.B., C.J., D.R.); and School of Chemistry, University of Nottingham, Nottingham, United Kingdom (R.R.A.K., C.J.M.)
David Siegel
Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado (C.-H.C., D.A.D., D.S., Q.Y., D.S.B., C.J., D.R.); and School of Chemistry, University of Nottingham, Nottingham, United Kingdom (R.R.A.K., C.J.M.)
Qiang You
Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado (C.-H.C., D.A.D., D.S., Q.Y., D.S.B., C.J., D.R.); and School of Chemistry, University of Nottingham, Nottingham, United Kingdom (R.R.A.K., C.J.M.)
Donald S. Backos
Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado (C.-H.C., D.A.D., D.S., Q.Y., D.S.B., C.J., D.R.); and School of Chemistry, University of Nottingham, Nottingham, United Kingdom (R.R.A.K., C.J.M.)
Cynthia Ju
Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado (C.-H.C., D.A.D., D.S., Q.Y., D.S.B., C.J., D.R.); and School of Chemistry, University of Nottingham, Nottingham, United Kingdom (R.R.A.K., C.J.M.)
Christopher J. Moody
Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado (C.-H.C., D.A.D., D.S., Q.Y., D.S.B., C.J., D.R.); and School of Chemistry, University of Nottingham, Nottingham, United Kingdom (R.R.A.K., C.J.M.)
David Ross
Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado (C.-H.C., D.A.D., D.S., Q.Y., D.S.B., C.J., D.R.); and School of Chemistry, University of Nottingham, Nottingham, United Kingdom (R.R.A.K., C.J.M.)

Submit a Response to This Article
Jump to comment:
No eLetters have been published for this article.
In this issue
Research ArticleArticle
Novel Hsp90 Inhibitors with Decreased Off-Target Toxicity
Chuan-Hsin Chang, Derek A. Drechsel, Russell R. A. Kitson, David Siegel, Qiang You, Donald S. Backos, Cynthia Ju, Christopher J. Moody and David Ross
Molecular Pharmacology June 1, 2014, 85 (6) 849-857; DOI: https://doi.org/10.1124/mol.113.090654
Research ArticleArticle
Novel Hsp90 Inhibitors with Decreased Off-Target Toxicity
Chuan-Hsin Chang, Derek A. Drechsel, Russell R. A. Kitson, David Siegel, Qiang You, Donald S. Backos, Cynthia Ju, Christopher J. Moody and David Ross
Molecular Pharmacology June 1, 2014, 85 (6) 849-857; DOI: https://doi.org/10.1124/mol.113.090654
Jump to section
Related Articles
Cited By...
More in this TOC Section
Similar Articles
Advertisement