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Molecular Pharmacology

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Research ArticleArticle

A Plasma Concentration of α-Ketoglutarate Influences the Kinetic Interaction of Ligands with Organic Anion Transporter 1

Leslie Ingraham, Mansong Li, J. Larry Renfro, Sonda Parker, Arpine Vapurcuyan, Imad Hanna and Ryan M. Pelis
Molecular Pharmacology July 2014, 86 (1) 86-95; DOI: https://doi.org/10.1124/mol.114.091777
Leslie Ingraham
Department of Pharmacology, Dalhousie University, Halifax, Nova Scotia, Canada (L.I., M.L., R.M.P.); Department of Physiology and Neurobiology, University of Connecticut, Storrs, Connecticut (J.L.R., S.P.); and Department of Drug Metabolism and Pharmacokinetics, Novartis Institutes for Biomedical Research, East Hanover, New Jersey (A.V., I.H.)
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Mansong Li
Department of Pharmacology, Dalhousie University, Halifax, Nova Scotia, Canada (L.I., M.L., R.M.P.); Department of Physiology and Neurobiology, University of Connecticut, Storrs, Connecticut (J.L.R., S.P.); and Department of Drug Metabolism and Pharmacokinetics, Novartis Institutes for Biomedical Research, East Hanover, New Jersey (A.V., I.H.)
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J. Larry Renfro
Department of Pharmacology, Dalhousie University, Halifax, Nova Scotia, Canada (L.I., M.L., R.M.P.); Department of Physiology and Neurobiology, University of Connecticut, Storrs, Connecticut (J.L.R., S.P.); and Department of Drug Metabolism and Pharmacokinetics, Novartis Institutes for Biomedical Research, East Hanover, New Jersey (A.V., I.H.)
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Sonda Parker
Department of Pharmacology, Dalhousie University, Halifax, Nova Scotia, Canada (L.I., M.L., R.M.P.); Department of Physiology and Neurobiology, University of Connecticut, Storrs, Connecticut (J.L.R., S.P.); and Department of Drug Metabolism and Pharmacokinetics, Novartis Institutes for Biomedical Research, East Hanover, New Jersey (A.V., I.H.)
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Arpine Vapurcuyan
Department of Pharmacology, Dalhousie University, Halifax, Nova Scotia, Canada (L.I., M.L., R.M.P.); Department of Physiology and Neurobiology, University of Connecticut, Storrs, Connecticut (J.L.R., S.P.); and Department of Drug Metabolism and Pharmacokinetics, Novartis Institutes for Biomedical Research, East Hanover, New Jersey (A.V., I.H.)
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Imad Hanna
Department of Pharmacology, Dalhousie University, Halifax, Nova Scotia, Canada (L.I., M.L., R.M.P.); Department of Physiology and Neurobiology, University of Connecticut, Storrs, Connecticut (J.L.R., S.P.); and Department of Drug Metabolism and Pharmacokinetics, Novartis Institutes for Biomedical Research, East Hanover, New Jersey (A.V., I.H.)
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Ryan M. Pelis
Department of Pharmacology, Dalhousie University, Halifax, Nova Scotia, Canada (L.I., M.L., R.M.P.); Department of Physiology and Neurobiology, University of Connecticut, Storrs, Connecticut (J.L.R., S.P.); and Department of Drug Metabolism and Pharmacokinetics, Novartis Institutes for Biomedical Research, East Hanover, New Jersey (A.V., I.H.)
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Molecular Pharmacology: 86 (1)
Molecular Pharmacology
Vol. 86, Issue 1
1 Jul 2014
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Research ArticleArticle

α-Ketoglutarate Affects Ligand Interactions with OAT1

Leslie Ingraham, Mansong Li, J. Larry Renfro, Sonda Parker, Arpine Vapurcuyan, Imad Hanna and Ryan M. Pelis
Molecular Pharmacology July 1, 2014, 86 (1) 86-95; DOI: https://doi.org/10.1124/mol.114.091777

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Research ArticleArticle

α-Ketoglutarate Affects Ligand Interactions with OAT1

Leslie Ingraham, Mansong Li, J. Larry Renfro, Sonda Parker, Arpine Vapurcuyan, Imad Hanna and Ryan M. Pelis
Molecular Pharmacology July 1, 2014, 86 (1) 86-95; DOI: https://doi.org/10.1124/mol.114.091777
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