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Molecular Pharmacology

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Research ArticleArticle

Gα13/PDZ-RhoGEF/RhoA Signaling Is Essential for Gastrin-Releasing Peptide Receptor–Mediated Colon Cancer Cell Migration

Maulik Patel, Takeharu Kawano, Nobuchika Suzuki, Takao Hamakubo, Andrei V. Karginov and Tohru Kozasa
Molecular Pharmacology September 2014, 86 (3) 252-262; DOI: https://doi.org/10.1124/mol.114.093914
Maulik Patel
Department of Pharmacology, University of Illinois at Chicago College of Medicine, Chicago, Illinois (M.P., A.V.K., T.Ko.); Department of Physiology and Biophysics, Virginia Commonwealth University School of Medicine, Richmond, Virginia (T. Ka.); and Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan (N.S., T.H., T.Ko.).
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Takeharu Kawano
Department of Pharmacology, University of Illinois at Chicago College of Medicine, Chicago, Illinois (M.P., A.V.K., T.Ko.); Department of Physiology and Biophysics, Virginia Commonwealth University School of Medicine, Richmond, Virginia (T. Ka.); and Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan (N.S., T.H., T.Ko.).
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Nobuchika Suzuki
Department of Pharmacology, University of Illinois at Chicago College of Medicine, Chicago, Illinois (M.P., A.V.K., T.Ko.); Department of Physiology and Biophysics, Virginia Commonwealth University School of Medicine, Richmond, Virginia (T. Ka.); and Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan (N.S., T.H., T.Ko.).
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Takao Hamakubo
Department of Pharmacology, University of Illinois at Chicago College of Medicine, Chicago, Illinois (M.P., A.V.K., T.Ko.); Department of Physiology and Biophysics, Virginia Commonwealth University School of Medicine, Richmond, Virginia (T. Ka.); and Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan (N.S., T.H., T.Ko.).
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Andrei V. Karginov
Department of Pharmacology, University of Illinois at Chicago College of Medicine, Chicago, Illinois (M.P., A.V.K., T.Ko.); Department of Physiology and Biophysics, Virginia Commonwealth University School of Medicine, Richmond, Virginia (T. Ka.); and Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan (N.S., T.H., T.Ko.).
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Tohru Kozasa
Department of Pharmacology, University of Illinois at Chicago College of Medicine, Chicago, Illinois (M.P., A.V.K., T.Ko.); Department of Physiology and Biophysics, Virginia Commonwealth University School of Medicine, Richmond, Virginia (T. Ka.); and Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan (N.S., T.H., T.Ko.).
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Article Information

vol. 86 no. 3 252-262
DOI 
https://doi.org/10.1124/mol.114.093914
PubMed 
24958816

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received May 19, 2014
  • Accepted June 13, 2014
  • Published online July 24, 2014.

Article Versions

  • Earlier version (June 23, 2014 - 09:16).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2014 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Maulik Patel,
  2. Takeharu Kawano,
  3. Nobuchika Suzuki,
  4. Takao Hamakubo,
  5. Andrei V. Karginov, and
  6. Tohru Kozasa
  1. Department of Pharmacology, University of Illinois at Chicago College of Medicine, Chicago, Illinois (M.P., A.V.K., T.Ko.); Department of Physiology and Biophysics, Virginia Commonwealth University School of Medicine, Richmond, Virginia (T. Ka.); and Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan (N.S., T.H., T.Ko.).
  1. Address correspondence to:
    Dr. Andrei Karginov, University of Illinois at Chicago, Department of Pharmacology, 5097 COMRB 909 S. Wolcott Ave. Chicago IL 60612. E-mail: karginov{at}uic.edu, or Dr. Tohru Kozasa, Laboratory of Systems Biology, and Medicine, Research Center for Advanced Science and Technology, University of Tokyo, 4, 6-1 Komaba, Meguro-ku, Tokyo 153-8904, Japan. E-mail: kozasa{at}lsbm.org
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Molecular Pharmacology: 86 (3)
Molecular Pharmacology
Vol. 86, Issue 3
1 Sep 2014
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Research ArticleArticle

PDZ-RhoGEF Drives Colon Cancer Cell Migration

Maulik Patel, Takeharu Kawano, Nobuchika Suzuki, Takao Hamakubo, Andrei V. Karginov and Tohru Kozasa
Molecular Pharmacology September 1, 2014, 86 (3) 252-262; DOI: https://doi.org/10.1124/mol.114.093914

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Research ArticleArticle

PDZ-RhoGEF Drives Colon Cancer Cell Migration

Maulik Patel, Takeharu Kawano, Nobuchika Suzuki, Takao Hamakubo, Andrei V. Karginov and Tohru Kozasa
Molecular Pharmacology September 1, 2014, 86 (3) 252-262; DOI: https://doi.org/10.1124/mol.114.093914
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