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Molecular Pharmacology

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Table of Contents

October 01, 2014; Volume 86,Issue 4

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    CB2 Cannabinoid Receptors as a Therapeutic Target—What Does the Future Hold?
    Amey Dhopeshwarkar and Ken Mackie
    Molecular Pharmacology October 2014, 86 (4) 430-437; DOI: https://doi.org/10.1124/mol.114.094649

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    Discovery and Mapping of an Intracellular Antagonist Binding Site at the Chemokine Receptor CCR2
    Annelien J.M. Zweemer, Julia Bunnik, Margo Veenhuizen, Fabiana Miraglia, Eelke B. Lenselink, Maris Vilums, Henk de Vries, Arthur Gibert, Stefanie Thiele, Mette M. Rosenkilde, Adriaan P. IJzerman and Laura H. Heitman
    Molecular Pharmacology October 2014, 86 (4) 358-368; DOI: https://doi.org/10.1124/mol.114.093328
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    G-Protein βγ Subunit Dimers Modulate Kidney Repair after Ischemia-Reperfusion Injury in Rats
    Sarah M. White, Lauren M. North, Emily Haines, Megan Goldberg, Lydia M. Sullivan, Jeffrey D. Pressly, David S. Weber, Frank Park and Kevin R. Regner
    Molecular Pharmacology October 2014, 86 (4) 369-377; DOI: https://doi.org/10.1124/mol.114.092346
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    Fluoxetine Blocks Nav1.5 Channels via a Mechanism Similar to That of Class 1 Antiarrhythmics
    Hugo Poulin, Iva Bruhova, Quadiri Timour, Olivier Theriault, Jean-Martin Beaulieu, Dominique Frassati and Mohamed Chahine
    Molecular Pharmacology October 2014, 86 (4) 378-389; DOI: https://doi.org/10.1124/mol.114.093104
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    A Role for Picomolar Concentrations of Pregnenolone Sulfate in Synaptic Activity-Dependent Ca2+ Signaling and CREB Activation
    Conor C. Smith, Stella C. Martin, Kavitha Sugunan, Shelley J. Russek, Terrell T. Gibbs and David H. Farb
    Molecular Pharmacology October 2014, 86 (4) 390-398; DOI: https://doi.org/10.1124/mol.114.094128
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    The Phosphatidylinositol(4,5)Bisphosphate–Binding Sequence of Transient Receptor Potential Channel Canonical 4α Is Critical for Its Contribution to Cardiomyocyte Hypertrophy
    Nicola Cooley, David R. Grubb, Jieting Luo and Elizabeth A. Woodcock
    Molecular Pharmacology October 2014, 86 (4) 399-405; DOI: https://doi.org/10.1124/mol.114.093690
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    Identification of Protein Kinase C Activation as a Novel Mechanism for RGS2 Protein Upregulation through Phenotypic Screening of Natural Product Extracts
    Avi Raveh, Pamela J. Schultz, Lauren Aschermann, Colleen Carpenter, Giselle Tamayo-Castillo, Shugeng Cao, Jon Clardy, Richard R. Neubig, David H. Sherman and Benita Sjögren
    Molecular Pharmacology October 2014, 86 (4) 406-416; DOI: https://doi.org/10.1124/mol.114.092403
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    Functional Selectivity of Allosteric Interactions within G Protein–Coupled Receptor Oligomers: The Dopamine D1-D3 Receptor Heterotetramer
    Xavier Guitart, Gemma Navarro, Estefania Moreno, Hideaki Yano, Ning-Sheng Cai, Marta Sánchez-Soto, Sandeep Kumar-Barodia, Yamini T. Naidu, Josefa Mallol, Antoni Cortés, Carme Lluís, Enric I. Canela, Vicent Casadó, Peter J. McCormick and Sergi Ferré
    Molecular Pharmacology October 2014, 86 (4) 417-429; DOI: https://doi.org/10.1124/mol.114.093096
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    Adverse Effects of Doxorubicin and Its Metabolic Product on Cardiac RyR2 and SERCA2A
    Amy D. Hanna, Alex Lam, Steffi Tham, Angela F. Dulhunty and Nicole A. Beard
    Molecular Pharmacology October 2014, 86 (4) 438-449; DOI: https://doi.org/10.1124/mol.114.093849
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    Regulation of Mitochondrial Poly(ADP-Ribose) Polymerase Activation by the β-Adrenoceptor/cAMP/Protein Kinase A Axis during Oxidative Stress
    Attila Brunyanszki, Gabor Olah, Ciro Coletta, Bartosz Szczesny and Csaba Szabo
    Molecular Pharmacology October 2014, 86 (4) 450-462; DOI: https://doi.org/10.1124/mol.114.094318
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In this issue

Molecular Pharmacology: 86 (4)
Molecular Pharmacology
Vol. 86, Issue 4
1 Oct 2014
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  • SB-431542 Is a Potent and Specific Inhibitor of Transforming Growth Factor-β Superfamily Type I Activin Receptor-Like Kinase (ALK) Receptors ALK4, ALK5, and ALK7
  • The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints
  • Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases
  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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