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Rapid CommunicationMinireview

CB2 Cannabinoid Receptors as a Therapeutic Target—What Does the Future Hold?

Amey Dhopeshwarkar and Ken Mackie
Molecular Pharmacology October 2014, 86 (4) 430-437; DOI: https://doi.org/10.1124/mol.114.094649
Amey Dhopeshwarkar
Department of Psychological and Brain Sciences and Gill Center, Indiana University, Bloomington, Indiana
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Ken Mackie
Department of Psychological and Brain Sciences and Gill Center, Indiana University, Bloomington, Indiana
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Article Information

vol. 86 no. 4 430-437
DOI 
https://doi.org/10.1124/mol.114.094649
PubMed 
25106425

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received July 7, 2014
  • Accepted August 8, 2014
  • Published online September 5, 2014.

Article Versions

  • Earlier version (August 8, 2014 - 10:18).
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Copyright & Usage 
Copyright © 2014 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Amey Dhopeshwarkar and
  2. Ken Mackie
  1. Department of Psychological and Brain Sciences and Gill Center, Indiana University, Bloomington, Indiana
  1. Address correspondence to:
    Ken Mackie, Department of Psychological and Brain Sciences and Gill Center, Indiana University, 1101 East 10th Street, Bloomington, IN 47405. E-mail: kmackie{at}indiana.edu
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Molecular Pharmacology: 86 (4)
Molecular Pharmacology
Vol. 86, Issue 4
1 Oct 2014
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Rapid CommunicationMinireview

CB2 as a Therapeutic Target

Amey Dhopeshwarkar and Ken Mackie
Molecular Pharmacology October 1, 2014, 86 (4) 430-437; DOI: https://doi.org/10.1124/mol.114.094649

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Rapid CommunicationMinireview

CB2 as a Therapeutic Target

Amey Dhopeshwarkar and Ken Mackie
Molecular Pharmacology October 1, 2014, 86 (4) 430-437; DOI: https://doi.org/10.1124/mol.114.094649
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  • Article
    • Abstract
    • Introduction
    • CB2 Receptors
    • Adenylyl Cyclase
    • MAPK
    • Ion Channels
    • Internalization
    • β-Arrestin Signaling
    • CB2 Receptor Dimerization
    • Functional Selectivity of CB2 Signaling
    • Regulation of CB2 Receptor Expression and CB2 Receptor Localization
    • CB2 Ligands
    • Genetic Tools To Study CB2 Receptor Signaling
    • Preclinical Studies of CB2 Agonists in Pain
    • Reconciling Preclinical and Clinical Studies
    • Concluding Comments
    • Authorship Contributions
    • Footnotes
    • Abbreviations
    • References
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