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Molecular Pharmacology

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Table of Contents

November 01, 2014; Volume 86,Issue 5

Special Section on Highlights from IUPHAR

  • You have access
    Advances in G Protein-Coupled Receptor Allostery: From Function to Structure
    Arthur Christopoulos
    Molecular Pharmacology November 2014, 86 (5) 463-478; DOI: https://doi.org/10.1124/mol.114.094342
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    The Odd Sibling: Features of β3-Adrenoceptor Pharmacology
    Hana Cernecka, Carsten Sand and Martin C. Michel
    Molecular Pharmacology November 2014, 86 (5) 479-484; DOI: https://doi.org/10.1124/mol.114.092817
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    Analyses of CD20 Monoclonal Antibody–Mediated Tumor Cell Killing Mechanisms: Rational Design of Dosing Strategies
    Ronald P. Taylor and Margaret A. Lindorfer
    Molecular Pharmacology November 2014, 86 (5) 485-491; DOI: https://doi.org/10.1124/mol.114.092684

Articles

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    Cooperative Signaling between Homodimers of Metabotropic Glutamate Receptors 1 and 5
    Tatyana N. Sevastyanova and Paul J. Kammermeier
    Molecular Pharmacology November 2014, 86 (5) 492-504; DOI: https://doi.org/10.1124/mol.114.093468
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    ABCD2 Alters Peroxisome Proliferator-Activated Receptor α Signaling In Vitro, but Does Not Impair Responses to Fenofibrate Therapy in a Mouse Model of Diet-Induced Obesity
    Xiaoxi Liu, Jingjing Liu, Shuang Liang, Agatha Schlüter, Stephane Fourcade, Stella Aslibekyan, Aurora Pujol and Gregory A. Graf
    Molecular Pharmacology November 2014, 86 (5) 505-513; DOI: https://doi.org/10.1124/mol.114.092742
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    Clemizole Hydrochloride Is a Novel and Potent Inhibitor of Transient Receptor Potential Channel TRPC5
    Julia M. Richter, Michael Schaefer and Kerstin Hill
    Molecular Pharmacology November 2014, 86 (5) 514-521; DOI: https://doi.org/10.1124/mol.114.093229
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    Robust Hydrolysis of Prostaglandin Glycerol Esters by Human Monoacylglycerol Lipase (MAGL)
    Juha R. Savinainen, Emilia Kansanen, Tatu Pantsar, Dina Navia-Paldanius, Teija Parkkari, Marko Lehtonen, Tuomo Laitinen, Tapio Nevalainen, Antti Poso, Anna-Liisa Levonen and Jarmo T. Laitinen
    Molecular Pharmacology November 2014, 86 (5) 522-535; DOI: https://doi.org/10.1124/mol.114.094284
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    A Methylation-Based Regulatory Network for MicroRNA 320a in Chemoresistant Breast Cancer
    Dong-Xu He, Xiao-Ting Gu, Li Jiang, Jian Jin and Xin Ma
    Molecular Pharmacology November 2014, 86 (5) 536-547; DOI: https://doi.org/10.1124/mol.114.092759
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    Structural Determinants and Mechanism of Action of a GluN2C-selective NMDA Receptor Positive Allosteric Modulator
    Alpa Khatri, Pieter B. Burger, Sharon A. Swanger, Kasper B. Hansen, Sommer Zimmerman, Erkan Karakas, Dennis C. Liotta, Hiro Furukawa, James P. Snyder and Stephen F. Traynelis
    Molecular Pharmacology November 2014, 86 (5) 548-560; DOI: https://doi.org/10.1124/mol.114.094516
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    Reversible Epigenetic Regulation of 14-3-3σ Expression in Acquired Gemcitabine Resistance by Uhrf1 and DNA Methyltransferase 1
    Li Qin, Zizheng Dong and Jian-Ting Zhang
    Molecular Pharmacology November 2014, 86 (5) 561-569; DOI: https://doi.org/10.1124/mol.114.092544
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    Activation of the Retinoid X Receptor Modulates Angiotensin II-Induced Smooth Muscle Gene Expression and Inflammation in Vascular Smooth Muscle Cells
    Allison M.B. Lehman, John R. Montford, Henrick Horita, Allison C. Ostriker, Mary C.M. Weiser-Evans, Raphael A. Nemenoff and Seth B. Furgeson
    Molecular Pharmacology November 2014, 86 (5) 570-579; DOI: https://doi.org/10.1124/mol.114.092163
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    Metformin Restores Intermediate-Conductance Calcium-Activated K+ Channel– and Small-Conductance Calcium-Activated K+ Channel–Mediated Vasodilatation Impaired by Advanced Glycation End Products in Rat Mesenteric Artery
    Li-Mei Zhao, Yan Wang, Yong Yang, Rong Guo, Nan-Ping Wang and Xiu-Ling Deng
    Molecular Pharmacology November 2014, 86 (5) 580-591; DOI: https://doi.org/10.1124/mol.114.092874
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    In Silico Identification of an Aryl Hydrocarbon Receptor Antagonist with Biological Activity In Vitro and In Vivo
    Ashley J. Parks, Michael P. Pollastri, Mark E. Hahn, Elizabeth A. Stanford, Olga Novikov, Diana G. Franks, Sarah E. Haigh, Supraja Narasimhan, Trent D. Ashton, Timothy G. Hopper, Dmytro Kozakov, Dimitri Beglov, Sandor Vajda, Jennifer J. Schlezinger and David H. Sherr
    Molecular Pharmacology November 2014, 86 (5) 593-608; DOI: https://doi.org/10.1124/mol.114.093369

Erratum

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    Correction to “The Kinetics of Competitive Radioligand Binding Predicted by the Law of Mass Action”
    Molecular Pharmacology November 2014, 86 (5) 592; DOI: https://doi.org/10.1124/mol.114.11er14
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In this issue

Molecular Pharmacology: 86 (5)
Molecular Pharmacology
Vol. 86, Issue 5
1 Nov 2014
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  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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