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Rapid CommunicationMinireview—Special Section on Highlights from IUPHAR

Advances in G Protein-Coupled Receptor Allostery: From Function to Structure

Arthur Christopoulos
Molecular Pharmacology November 2014, 86 (5) 463-478; DOI: https://doi.org/10.1124/mol.114.094342
Arthur Christopoulos
Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences and Department of Pharmacology, Monash University, Parkville, Victoria, Australia
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Molecular Pharmacology: 86 (5)
Molecular Pharmacology
Vol. 86, Issue 5
1 Nov 2014
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Rapid CommunicationMinireview—Special Section on Highlights from IUPHAR

Advances in GPCR Allostery

Arthur Christopoulos
Molecular Pharmacology November 1, 2014, 86 (5) 463-478; DOI: https://doi.org/10.1124/mol.114.094342

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Rapid CommunicationMinireview—Special Section on Highlights from IUPHAR

Advances in GPCR Allostery

Arthur Christopoulos
Molecular Pharmacology November 1, 2014, 86 (5) 463-478; DOI: https://doi.org/10.1124/mol.114.094342
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  • Article
    • Abstract
    • Introduction
    • Classification of Allosteric Modulators
    • Pharmacologic Characteristics of GPCR Allostery
    • Enriching Structure-Activity Studies of GPCR Allostery and Bias
    • Bitopic GPCR Ligands
    • Endogenous Allosteric Modulators
    • Understanding the Structural Basis of GPCR Allostery
    • Concluding Remarks
    • Acknowledgments
    • Footnotes
    • Abbreviations
    • References
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