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Molecular Pharmacology

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Table of Contents

December 01, 2014; Volume 86,Issue 6

Minireviews

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    NADPH Oxidases as Novel Pharmacologic Targets against Influenza A Virus Infection
    Ross Vlahos and Stavros Selemidis
    Molecular Pharmacology December 2014, 86 (6) 747-759; DOI: https://doi.org/10.1124/mol.114.095216
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    Location-Dependent Signaling of the Group 1 Metabotropic Glutamate Receptor mGlu5
    Yuh-Jiin I. Jong, Ismail Sergin, Carolyn A. Purgert and Karen L. O’Malley
    Molecular Pharmacology December 2014, 86 (6) 774-785; DOI: https://doi.org/10.1124/mol.114.094763

Articles

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    Berberine Reverses Epithelial-to-Mesenchymal Transition and Inhibits Metastasis and Tumor-Induced Angiogenesis in Human Cervical Cancer Cells
    Shu-Chen Chu, Cheng-Chia Yu, Li-Sung Hsu, Kuo-Shuen Chen, Mei-Yu Su and Pei-Ni Chen
    Molecular Pharmacology December 2014, 86 (6) 609-623; DOI: https://doi.org/10.1124/mol.114.094037
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    The WNT/β-Catenin Pathway Is a Transcriptional Regulator of CYP2E1, CYP1A2, and Aryl Hydrocarbon Receptor Gene Expression in Primary Human Hepatocytes
    Sabine Gerbal-Chaloin, Anne-Sophie Dumé, Philippe Briolotti, Sylvie Klieber, Edith Raulet, Cédric Duret, Jean-Michel Fabre, Jeanne Ramos, Patrick Maurel and Martine Daujat-Chavanieu
    Molecular Pharmacology December 2014, 86 (6) 624-634; DOI: https://doi.org/10.1124/mol.114.094797
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    Glycine and GABAA Ultra-Sensitive Ethanol Receptors as Novel Tools for Alcohol and Brain Research
    Anna Naito, Karan H. Muchhala, Liana Asatryan, James R. Trudell, Gregg E. Homanics, Daya I. Perkins, Daryl L. Davies and Ronald L. Alkana
    Molecular Pharmacology December 2014, 86 (6) 635-646; DOI: https://doi.org/10.1124/mol.114.093773
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    γ-Aminobutyric Acid Type A α4, β2, and δ Subunits Assemble to Produce More Than One Functionally Distinct Receptor Type
    Megan M. Eaton, John Bracamontes, Hong-Jin Shu, Ping Li, Steven Mennerick, Joe Henry Steinbach and Gustav Akk
    Molecular Pharmacology December 2014, 86 (6) 647-656; DOI: https://doi.org/10.1124/mol.114.094813
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    Investigating Substrate-Induced Motion between the Scaffold and Transport Domains in the Glutamate Transporter EAAT1
    Xiuliang Rong, Elia Zomot, Xiuping Zhang and Shaogang Qu
    Molecular Pharmacology December 2014, 86 (6) 657-664; DOI: https://doi.org/10.1124/mol.114.094995
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    Characterization of Ritonavir-Mediated Inactivation of Cytochrome P450 3A4
    Brooke M. Rock, Shawna M. Hengel, Dan A. Rock, Larry C. Wienkers and Kent L. Kunze
    Molecular Pharmacology December 2014, 86 (6) 665-674; DOI: https://doi.org/10.1124/mol.114.094862
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    Norepinephrine Transporter Inhibition with Desipramine Exacerbates L-DOPA–Induced Dyskinesia: Role for Synaptic Dopamine Regulation in Denervated Nigrostriatal Terminals
    Tanya Chotibut, Victoria Fields and Michael F. Salvatore
    Molecular Pharmacology December 2014, 86 (6) 675-685; DOI: https://doi.org/10.1124/mol.114.093302
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    Exon 3 Splicing and Mutagenesis Identify Residues Influencing Cell Surface Density of Heterologously Expressed Silkworm (Bombyx mori) Glutamate-Gated Chloride Channels
    Shogo Furutani, Makoto Ihara, Yuri Nishino, Miki Akamatsu, Andrew K. Jones, David B. Sattelle and Kazuhiko Matsuda
    Molecular Pharmacology December 2014, 86 (6) 686-695; DOI: https://doi.org/10.1124/mol.114.095869
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    Multiple Modes of Ryanodine Receptor 2 Inhibition by Flecainide
    D. Mehra, M. S. Imtiaz, D. F. van Helden, B. C. Knollmann and D. R. Laver
    Molecular Pharmacology December 2014, 86 (6) 696-706; DOI: https://doi.org/10.1124/mol.114.094623
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    Kinetics of Conformational Changes Revealed by Voltage-Clamp Fluorometry Give Insight to Desensitization at ATP-Gated Human P2X1 Receptors
    Alistair G. Fryatt and Richard J. Evans
    Molecular Pharmacology December 2014, 86 (6) 707-715; DOI: https://doi.org/10.1124/mol.114.095307
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    In Silico Screening for Inhibitors of P-Glycoprotein That Target the Nucleotide Binding Domains
    Frances K. Brewer, Courtney A. Follit, Pia D. Vogel and John G. Wise
    Molecular Pharmacology December 2014, 86 (6) 716-726; DOI: https://doi.org/10.1124/mol.114.095414
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    Krüppel-Like Factor 9 Promotes Hepatic Cytochrome P450 2D6 Expression during Pregnancy in CYP2D6-Humanized Mice
    Kwi Hye Koh, Xian Pan, Wei Zhang, Alan McLachlan, Raul Urrutia and Hyunyoung Jeong
    Molecular Pharmacology December 2014, 86 (6) 727-735; DOI: https://doi.org/10.1124/mol.114.093666
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    Studies on an Acetylcholine Binding Protein Identify a Basic Residue in Loop G on the β1 Strand as a New Structural Determinant of Neonicotinoid Actions
    Makoto Ihara, Toshihide Okajima, Atsuko Yamashita, Takuma Oda, Takuya Asano, Mikana Matsui, David B. Sattelle and Kazuhiko Matsuda
    Molecular Pharmacology December 2014, 86 (6) 736-746; DOI: https://doi.org/10.1124/mol.114.094698
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    Potentiation of High Voltage–Activated Calcium Channels by 4-Aminopyridine Depends on Subunit Composition
    Li Li, De-Pei Li, Shao-Rui Chen, Jinjun Chen, Hongzhen Hu and Hui-Lin Pan
    Molecular Pharmacology December 2014, 86 (6) 760-772; DOI: https://doi.org/10.1124/mol.114.095505

Erratum

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    Correction to “Metformin Restores Intermediate-Conductance Calcium-Activated K+ Channel- and Small-Conductance Calcium-Activated K+ Channel-Mediated Vasodilatation Impaired by Advanced Glycation End Products in Rat Mesenteric Artery”
    Molecular Pharmacology December 2014, 86 (6) 773; DOI: https://doi.org/10.1124/mol.114.092874err
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In this issue

Molecular Pharmacology: 86 (6)
Molecular Pharmacology
Vol. 86, Issue 6
1 Dec 2014
  • Table of Contents
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  • Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases
  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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