Research ArticleArticle
The WNT/β-Catenin Pathway Is a Transcriptional Regulator of CYP2E1, CYP1A2, and Aryl Hydrocarbon Receptor Gene Expression in Primary Human Hepatocytes
Sabine Gerbal-Chaloin, Anne-Sophie Dumé, Philippe Briolotti, Sylvie Klieber, Edith Raulet, Cédric Duret, Jean-Michel Fabre, Jeanne Ramos, Patrick Maurel and Martine Daujat-Chavanieu
Molecular Pharmacology December 2014, 86 (6) 624-634; DOI: https://doi.org/10.1124/mol.114.094797
Sabine Gerbal-Chaloin
Institut de Recherche en Biothérapie, INSERM, U1040 (S.G.C., A.S.D., P.B., E.R., C.D., P.M., M.D.C.); UMR 1040, Université Montpellier 1 (S.G.C., A.S.D., P.B., E.R., C.D., P.M., M.D.C.); Drug Disposition Domain, Sanofi Aventis (S.K.); Department of Digestive Surgery, CHU Saint Eloi (J.M.F.); Pathological Anatomy Department, CHU Gui de Chauliac (J.R.); and Institut de Recherche en Biothérapie, CHU Montpellier, (M.D.C.), Montpellier, France
Anne-Sophie Dumé
Institut de Recherche en Biothérapie, INSERM, U1040 (S.G.C., A.S.D., P.B., E.R., C.D., P.M., M.D.C.); UMR 1040, Université Montpellier 1 (S.G.C., A.S.D., P.B., E.R., C.D., P.M., M.D.C.); Drug Disposition Domain, Sanofi Aventis (S.K.); Department of Digestive Surgery, CHU Saint Eloi (J.M.F.); Pathological Anatomy Department, CHU Gui de Chauliac (J.R.); and Institut de Recherche en Biothérapie, CHU Montpellier, (M.D.C.), Montpellier, France
Philippe Briolotti
Institut de Recherche en Biothérapie, INSERM, U1040 (S.G.C., A.S.D., P.B., E.R., C.D., P.M., M.D.C.); UMR 1040, Université Montpellier 1 (S.G.C., A.S.D., P.B., E.R., C.D., P.M., M.D.C.); Drug Disposition Domain, Sanofi Aventis (S.K.); Department of Digestive Surgery, CHU Saint Eloi (J.M.F.); Pathological Anatomy Department, CHU Gui de Chauliac (J.R.); and Institut de Recherche en Biothérapie, CHU Montpellier, (M.D.C.), Montpellier, France
Sylvie Klieber
Institut de Recherche en Biothérapie, INSERM, U1040 (S.G.C., A.S.D., P.B., E.R., C.D., P.M., M.D.C.); UMR 1040, Université Montpellier 1 (S.G.C., A.S.D., P.B., E.R., C.D., P.M., M.D.C.); Drug Disposition Domain, Sanofi Aventis (S.K.); Department of Digestive Surgery, CHU Saint Eloi (J.M.F.); Pathological Anatomy Department, CHU Gui de Chauliac (J.R.); and Institut de Recherche en Biothérapie, CHU Montpellier, (M.D.C.), Montpellier, France
Edith Raulet
Institut de Recherche en Biothérapie, INSERM, U1040 (S.G.C., A.S.D., P.B., E.R., C.D., P.M., M.D.C.); UMR 1040, Université Montpellier 1 (S.G.C., A.S.D., P.B., E.R., C.D., P.M., M.D.C.); Drug Disposition Domain, Sanofi Aventis (S.K.); Department of Digestive Surgery, CHU Saint Eloi (J.M.F.); Pathological Anatomy Department, CHU Gui de Chauliac (J.R.); and Institut de Recherche en Biothérapie, CHU Montpellier, (M.D.C.), Montpellier, France
Cédric Duret
Institut de Recherche en Biothérapie, INSERM, U1040 (S.G.C., A.S.D., P.B., E.R., C.D., P.M., M.D.C.); UMR 1040, Université Montpellier 1 (S.G.C., A.S.D., P.B., E.R., C.D., P.M., M.D.C.); Drug Disposition Domain, Sanofi Aventis (S.K.); Department of Digestive Surgery, CHU Saint Eloi (J.M.F.); Pathological Anatomy Department, CHU Gui de Chauliac (J.R.); and Institut de Recherche en Biothérapie, CHU Montpellier, (M.D.C.), Montpellier, France
Jean-Michel Fabre
Institut de Recherche en Biothérapie, INSERM, U1040 (S.G.C., A.S.D., P.B., E.R., C.D., P.M., M.D.C.); UMR 1040, Université Montpellier 1 (S.G.C., A.S.D., P.B., E.R., C.D., P.M., M.D.C.); Drug Disposition Domain, Sanofi Aventis (S.K.); Department of Digestive Surgery, CHU Saint Eloi (J.M.F.); Pathological Anatomy Department, CHU Gui de Chauliac (J.R.); and Institut de Recherche en Biothérapie, CHU Montpellier, (M.D.C.), Montpellier, France
Jeanne Ramos
Institut de Recherche en Biothérapie, INSERM, U1040 (S.G.C., A.S.D., P.B., E.R., C.D., P.M., M.D.C.); UMR 1040, Université Montpellier 1 (S.G.C., A.S.D., P.B., E.R., C.D., P.M., M.D.C.); Drug Disposition Domain, Sanofi Aventis (S.K.); Department of Digestive Surgery, CHU Saint Eloi (J.M.F.); Pathological Anatomy Department, CHU Gui de Chauliac (J.R.); and Institut de Recherche en Biothérapie, CHU Montpellier, (M.D.C.), Montpellier, France
Patrick Maurel
Institut de Recherche en Biothérapie, INSERM, U1040 (S.G.C., A.S.D., P.B., E.R., C.D., P.M., M.D.C.); UMR 1040, Université Montpellier 1 (S.G.C., A.S.D., P.B., E.R., C.D., P.M., M.D.C.); Drug Disposition Domain, Sanofi Aventis (S.K.); Department of Digestive Surgery, CHU Saint Eloi (J.M.F.); Pathological Anatomy Department, CHU Gui de Chauliac (J.R.); and Institut de Recherche en Biothérapie, CHU Montpellier, (M.D.C.), Montpellier, France
Martine Daujat-Chavanieu
Institut de Recherche en Biothérapie, INSERM, U1040 (S.G.C., A.S.D., P.B., E.R., C.D., P.M., M.D.C.); UMR 1040, Université Montpellier 1 (S.G.C., A.S.D., P.B., E.R., C.D., P.M., M.D.C.); Drug Disposition Domain, Sanofi Aventis (S.K.); Department of Digestive Surgery, CHU Saint Eloi (J.M.F.); Pathological Anatomy Department, CHU Gui de Chauliac (J.R.); and Institut de Recherche en Biothérapie, CHU Montpellier, (M.D.C.), Montpellier, France
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Research ArticleArticle
β-Catenin Regulates Drug Metabolism
Sabine Gerbal-Chaloin, Anne-Sophie Dumé, Philippe Briolotti, Sylvie Klieber, Edith Raulet, Cédric Duret, Jean-Michel Fabre, Jeanne Ramos, Patrick Maurel and Martine Daujat-Chavanieu
Molecular Pharmacology December 1, 2014, 86 (6) 624-634; DOI: https://doi.org/10.1124/mol.114.094797
Research ArticleArticle
β-Catenin Regulates Drug Metabolism
Sabine Gerbal-Chaloin, Anne-Sophie Dumé, Philippe Briolotti, Sylvie Klieber, Edith Raulet, Cédric Duret, Jean-Michel Fabre, Jeanne Ramos, Patrick Maurel and Martine Daujat-Chavanieu
Molecular Pharmacology December 1, 2014, 86 (6) 624-634; DOI: https://doi.org/10.1124/mol.114.094797
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