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Molecular Pharmacology

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    • Current Issue
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Index by author

February 01, 2015; Volume 87,Issue 2
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Abkhezr, Mousa

    1. You have access
      RETRACTION: STAT3 Regulates Steady-State Expression of Synaptopodin in Cultured Mouse Podocytes
      Mousa Abkhezr and Stuart E. Dryer
      Molecular Pharmacology February 2015, 87 (2) 231-239; DOI: https://doi.org/10.1124/mol.114.094508
  2. Adams, David J.

    1. You have access
      Novel Mechanism of Voltage-Gated N-type (Cav2.2) Calcium Channel Inhibition Revealed through α-Conotoxin Vc1.1 Activation of the GABAB Receptor
      Thuan G. Huynh, Hartmut Cuny, Paul A. Slesinger and David J. Adams
      Molecular Pharmacology February 2015, 87 (2) 240-250; DOI: https://doi.org/10.1124/mol.114.096156
  3. Akamine, Takahiro

    1. You have access
      Modulation of Peroxisome Proliferator-Activated Receptor-α Activity by Bile Acids Causes Circadian Changes in the Intestinal Expression of Octn1/Slc22a4 in Mice
      Erika Wada, Satoru Koyanagi, Naoki Kusunose, Takahiro Akamine, Hiroaki Masui, Hana Hashimoto, Naoya Matsunaga and Shigehiro Ohdo
      Molecular Pharmacology February 2015, 87 (2) 314-322; DOI: https://doi.org/10.1124/mol.114.094979
  4. Al-Sabah, Suleiman

    1. You have access
      Engineered Hyperphosphorylation of the β2-Adrenoceptor Prolongs Arrestin-3 Binding and Induces Arrestin Internalization
      Diana Zindel, Adrian J. Butcher, Suleiman Al-Sabah, Peter Lanzerstorfer, Julian Weghuber, Andrew B. Tobin, Moritz Bünemann and Cornelius Krasel
      Molecular Pharmacology February 2015, 87 (2) 349-362; DOI: https://doi.org/10.1124/mol.114.095422
  5. Alfonso-Prieto, Mercedes

    1. You have access
      An Integrated Biological Approach to Guide the Development of Metal-Chelating Inhibitors of Influenza Virus PA Endonuclease
      Annelies Stevaert, Salvatore Nurra, Nicolino Pala, Mauro Carcelli, Dominga Rogolino, Caitlin Shepard, Robert A. Domaoal, Baek Kim, Mercedes Alfonso-Prieto, Salvatore A. E. Marras, Mario Sechi and Lieve Naesens
      Molecular Pharmacology February 2015, 87 (2) 323-337; DOI: https://doi.org/10.1124/mol.114.095588
  6. Almahariq, Muayad

    1. You have access
      Pharmacological Inhibition and Genetic Knockdown of Exchange Protein Directly Activated by cAMP 1 Reduce Pancreatic Cancer Metastasis In Vivo
      Muayad Almahariq, Celia Chao, Fang C. Mei, Mark R. Hellmich, Igor Patrikeev, Massoud Motamedi and Xiaodong Cheng
      Molecular Pharmacology February 2015, 87 (2) 142-149; DOI: https://doi.org/10.1124/mol.114.095158
  7. Ann, David

    1. You have access
      A Peptide Mimicking a Region in Proliferating Cell Nuclear Antigen Specific to Key Protein Interactions Is Cytotoxic to Breast Cancer
      Shanna J. Smith, Long Gu, Elizabeth A. Phipps, Lacey E. Dobrolecki, Karla S. Mabrey, Pattie Gulley, Kelsey L. Dillehay, Zhongyun Dong, Gregg B. Fields, Yun-Ru Chen, David Ann, Robert J. Hickey and Linda H. Malkas
      Molecular Pharmacology February 2015, 87 (2) 263-276; DOI: https://doi.org/10.1124/mol.114.093211
  8. Arcangeli, Annarosa

    1. You have access
      New Pyrimido-Indole Compound CD-160130 Preferentially Inhibits the KV11.1B Isoform and Produces Antileukemic Effects without Cardiotoxicity
      Luca Gasparoli, Massimo D’Amico, Marika Masselli, Serena Pillozzi, Rachel Caves, Rawan Khuwaileh, Wolfgang Tiedke, Kenneth Mugridge, Alessandro Pratesi, John S. Mitcheson, Giuseppe Basso, Andrea Becchetti and Annarosa Arcangeli
      Molecular Pharmacology February 2015, 87 (2) 183-196; DOI: https://doi.org/10.1124/mol.114.094920

B

  1. Badorrey, Ramón

    1. You have access
      A Novel Pan-Negative-Gating Modulator of KCa2/3 Channels, Fluoro-Di-Benzoate, RA-2, Inhibits Endothelium-Derived Hyperpolarization–Type Relaxation in Coronary Artery and Produces Bradycardia In Vivo
      Aida Oliván-Viguera, Marta Sofía Valero, Nicole Coleman, Brandon M. Brown, Celia Laría, María Divina Murillo, José A. Gálvez, María D. Díaz-de-Villegas, Heike Wulff, Ramón Badorrey and Ralf Köhler
      Molecular Pharmacology February 2015, 87 (2) 338-348; DOI: https://doi.org/10.1124/mol.114.095745
  2. Bai, Yongheng

    1. You have access
      An Overview of Hedgehog Signaling in Fibrosis
      Liping Hu, Xiangyang Lin, Hong Lu, Bicheng Chen and Yongheng Bai
      Molecular Pharmacology February 2015, 87 (2) 174-182; DOI: https://doi.org/10.1124/mol.114.095141
  3. Basso, Giuseppe

    1. You have access
      New Pyrimido-Indole Compound CD-160130 Preferentially Inhibits the KV11.1B Isoform and Produces Antileukemic Effects without Cardiotoxicity
      Luca Gasparoli, Massimo D’Amico, Marika Masselli, Serena Pillozzi, Rachel Caves, Rawan Khuwaileh, Wolfgang Tiedke, Kenneth Mugridge, Alessandro Pratesi, John S. Mitcheson, Giuseppe Basso, Andrea Becchetti and Annarosa Arcangeli
      Molecular Pharmacology February 2015, 87 (2) 183-196; DOI: https://doi.org/10.1124/mol.114.094920
  4. Becchetti, Andrea

    1. You have access
      New Pyrimido-Indole Compound CD-160130 Preferentially Inhibits the KV11.1B Isoform and Produces Antileukemic Effects without Cardiotoxicity
      Luca Gasparoli, Massimo D’Amico, Marika Masselli, Serena Pillozzi, Rachel Caves, Rawan Khuwaileh, Wolfgang Tiedke, Kenneth Mugridge, Alessandro Pratesi, John S. Mitcheson, Giuseppe Basso, Andrea Becchetti and Annarosa Arcangeli
      Molecular Pharmacology February 2015, 87 (2) 183-196; DOI: https://doi.org/10.1124/mol.114.094920
  5. Bradley, M. E.

    1. You have access
      Potent and Efficacious Inhibition of CXCR2 Signaling by Biparatopic Nanobodies Combining Two Distinct Modes of Action
      M. E. Bradley, B. Dombrecht, J. Manini, J. Willis, D. Vlerick, S. De Taeye, K. Van den Heede, A. Roobrouck, E. Grot, T. C. Kent, T. Laeremans, S. Steffensen, G. Van Heeke, Z. Brown, S. J. Charlton and K. D. Cromie
      Molecular Pharmacology February 2015, 87 (2) 251-262; DOI: https://doi.org/10.1124/mol.114.094821
  6. Brendel, Cornelia

    1. You have access
      The Inverse Agonist DG172 Triggers a PPARβ/δ-Independent Myeloid Lineage Shift and Promotes GM-CSF/IL-4-Induced Dendritic Cell Differentiation
      Sonja Lieber, Frithjof Scheer, Florian Finkernagel, Wolfgang Meissner, Gavin Giehl, Cornelia Brendel, Wibke E. Diederich, Sabine Müller-Brüsselbach and Rolf Müller
      Molecular Pharmacology February 2015, 87 (2) 162-173; DOI: https://doi.org/10.1124/mol.114.094672
  7. Brown, Brandon M.

    1. You have access
      A Novel Pan-Negative-Gating Modulator of KCa2/3 Channels, Fluoro-Di-Benzoate, RA-2, Inhibits Endothelium-Derived Hyperpolarization–Type Relaxation in Coronary Artery and Produces Bradycardia In Vivo
      Aida Oliván-Viguera, Marta Sofía Valero, Nicole Coleman, Brandon M. Brown, Celia Laría, María Divina Murillo, José A. Gálvez, María D. Díaz-de-Villegas, Heike Wulff, Ramón Badorrey and Ralf Köhler
      Molecular Pharmacology February 2015, 87 (2) 338-348; DOI: https://doi.org/10.1124/mol.114.095745
  8. Brown, Z.

    1. You have access
      Potent and Efficacious Inhibition of CXCR2 Signaling by Biparatopic Nanobodies Combining Two Distinct Modes of Action
      M. E. Bradley, B. Dombrecht, J. Manini, J. Willis, D. Vlerick, S. De Taeye, K. Van den Heede, A. Roobrouck, E. Grot, T. C. Kent, T. Laeremans, S. Steffensen, G. Van Heeke, Z. Brown, S. J. Charlton and K. D. Cromie
      Molecular Pharmacology February 2015, 87 (2) 251-262; DOI: https://doi.org/10.1124/mol.114.094821
  9. Bünemann, Moritz

    1. You have access
      Engineered Hyperphosphorylation of the β2-Adrenoceptor Prolongs Arrestin-3 Binding and Induces Arrestin Internalization
      Diana Zindel, Adrian J. Butcher, Suleiman Al-Sabah, Peter Lanzerstorfer, Julian Weghuber, Andrew B. Tobin, Moritz Bünemann and Cornelius Krasel
      Molecular Pharmacology February 2015, 87 (2) 349-362; DOI: https://doi.org/10.1124/mol.114.095422
  10. Buss, Meghan C.

    1. You have access
      Insulin-Like Growth Factor-1 Receptor Signaling Increases the Invasive Potential of Human Epidermal Growth Factor Receptor 2–Overexpressing Breast Cancer Cells via Src-Focal Adhesion Kinase and Forkhead Box Protein M1
      Eduardo Sanabria-Figueroa, Siobhan M. Donnelly, Kevin C. Foy, Meghan C. Buss, Robert C. Castellino, Elisavet Paplomata, Latonia Taliaferro-Smith, Pravin T.P. Kaumaya and Rita Nahta
      Molecular Pharmacology February 2015, 87 (2) 150-161; DOI: https://doi.org/10.1124/mol.114.095380
  11. Butcher, Adrian J.

    1. You have access
      Engineered Hyperphosphorylation of the β2-Adrenoceptor Prolongs Arrestin-3 Binding and Induces Arrestin Internalization
      Diana Zindel, Adrian J. Butcher, Suleiman Al-Sabah, Peter Lanzerstorfer, Julian Weghuber, Andrew B. Tobin, Moritz Bünemann and Cornelius Krasel
      Molecular Pharmacology February 2015, 87 (2) 349-362; DOI: https://doi.org/10.1124/mol.114.095422

C

  1. Carcelli, Mauro

    1. You have access
      An Integrated Biological Approach to Guide the Development of Metal-Chelating Inhibitors of Influenza Virus PA Endonuclease
      Annelies Stevaert, Salvatore Nurra, Nicolino Pala, Mauro Carcelli, Dominga Rogolino, Caitlin Shepard, Robert A. Domaoal, Baek Kim, Mercedes Alfonso-Prieto, Salvatore A. E. Marras, Mario Sechi and Lieve Naesens
      Molecular Pharmacology February 2015, 87 (2) 323-337; DOI: https://doi.org/10.1124/mol.114.095588
  2. Castellino, Robert C.

    1. You have access
      Insulin-Like Growth Factor-1 Receptor Signaling Increases the Invasive Potential of Human Epidermal Growth Factor Receptor 2–Overexpressing Breast Cancer Cells via Src-Focal Adhesion Kinase and Forkhead Box Protein M1
      Eduardo Sanabria-Figueroa, Siobhan M. Donnelly, Kevin C. Foy, Meghan C. Buss, Robert C. Castellino, Elisavet Paplomata, Latonia Taliaferro-Smith, Pravin T.P. Kaumaya and Rita Nahta
      Molecular Pharmacology February 2015, 87 (2) 150-161; DOI: https://doi.org/10.1124/mol.114.095380
  3. Caves, Rachel

    1. You have access
      New Pyrimido-Indole Compound CD-160130 Preferentially Inhibits the KV11.1B Isoform and Produces Antileukemic Effects without Cardiotoxicity
      Luca Gasparoli, Massimo D’Amico, Marika Masselli, Serena Pillozzi, Rachel Caves, Rawan Khuwaileh, Wolfgang Tiedke, Kenneth Mugridge, Alessandro Pratesi, John S. Mitcheson, Giuseppe Basso, Andrea Becchetti and Annarosa Arcangeli
      Molecular Pharmacology February 2015, 87 (2) 183-196; DOI: https://doi.org/10.1124/mol.114.094920
  4. Chang, Mi Ra

    1. You have access
      Antiproliferation Activity of a Small Molecule Repressor of Liver Receptor Homolog 1
      Cesar A. Corzo, Yelenis Mari, Mi Ra Chang, Tanya Khan, Dana Kuruvilla, Philippe Nuhant, Naresh Kumar, Graham M. West, Derek R. Duckett, William R. Roush and Patrick R. Griffin
      Molecular Pharmacology February 2015, 87 (2) 296-304; DOI: https://doi.org/10.1124/mol.114.095554
  5. Chao, Celia

    1. You have access
      Pharmacological Inhibition and Genetic Knockdown of Exchange Protein Directly Activated by cAMP 1 Reduce Pancreatic Cancer Metastasis In Vivo
      Muayad Almahariq, Celia Chao, Fang C. Mei, Mark R. Hellmich, Igor Patrikeev, Massoud Motamedi and Xiaodong Cheng
      Molecular Pharmacology February 2015, 87 (2) 142-149; DOI: https://doi.org/10.1124/mol.114.095158
  6. Charlton, S. J.

    1. You have access
      Potent and Efficacious Inhibition of CXCR2 Signaling by Biparatopic Nanobodies Combining Two Distinct Modes of Action
      M. E. Bradley, B. Dombrecht, J. Manini, J. Willis, D. Vlerick, S. De Taeye, K. Van den Heede, A. Roobrouck, E. Grot, T. C. Kent, T. Laeremans, S. Steffensen, G. Van Heeke, Z. Brown, S. J. Charlton and K. D. Cromie
      Molecular Pharmacology February 2015, 87 (2) 251-262; DOI: https://doi.org/10.1124/mol.114.094821
  7. Chen, Bicheng

    1. You have access
      An Overview of Hedgehog Signaling in Fibrosis
      Liping Hu, Xiangyang Lin, Hong Lu, Bicheng Chen and Yongheng Bai
      Molecular Pharmacology February 2015, 87 (2) 174-182; DOI: https://doi.org/10.1124/mol.114.095141
  8. Chen, Wang-Chuan

    1. You have access
      Phage Display–Mediated Discovery of Novel Tyrosinase-Targeting Tetrapeptide Inhibitors Reveals the Significance of N-Terminal Preference of Cysteine Residues and Their Functional Sulfur Atom
      Yu-Ching Lee, Nai-Wan Hsiao, Tien-Sheng Tseng, Wang-Chuan Chen, Hui-Hsiung Lin, Sy-Jye Leu, Ei-Wen Yang and Keng-Chang Tsai
      Molecular Pharmacology February 2015, 87 (2) 218-230; DOI: https://doi.org/10.1124/mol.114.094185
  9. Chen, Yun-Ru

    1. You have access
      A Peptide Mimicking a Region in Proliferating Cell Nuclear Antigen Specific to Key Protein Interactions Is Cytotoxic to Breast Cancer
      Shanna J. Smith, Long Gu, Elizabeth A. Phipps, Lacey E. Dobrolecki, Karla S. Mabrey, Pattie Gulley, Kelsey L. Dillehay, Zhongyun Dong, Gregg B. Fields, Yun-Ru Chen, David Ann, Robert J. Hickey and Linda H. Malkas
      Molecular Pharmacology February 2015, 87 (2) 263-276; DOI: https://doi.org/10.1124/mol.114.093211
  10. Cheng, Xiaodong

    1. You have access
      Pharmacological Inhibition and Genetic Knockdown of Exchange Protein Directly Activated by cAMP 1 Reduce Pancreatic Cancer Metastasis In Vivo
      Muayad Almahariq, Celia Chao, Fang C. Mei, Mark R. Hellmich, Igor Patrikeev, Massoud Motamedi and Xiaodong Cheng
      Molecular Pharmacology February 2015, 87 (2) 142-149; DOI: https://doi.org/10.1124/mol.114.095158
  11. Coleman, Nicole

    1. You have access
      A Novel Pan-Negative-Gating Modulator of KCa2/3 Channels, Fluoro-Di-Benzoate, RA-2, Inhibits Endothelium-Derived Hyperpolarization–Type Relaxation in Coronary Artery and Produces Bradycardia In Vivo
      Aida Oliván-Viguera, Marta Sofía Valero, Nicole Coleman, Brandon M. Brown, Celia Laría, María Divina Murillo, José A. Gálvez, María D. Díaz-de-Villegas, Heike Wulff, Ramón Badorrey and Ralf Köhler
      Molecular Pharmacology February 2015, 87 (2) 338-348; DOI: https://doi.org/10.1124/mol.114.095745
  12. Corzo, Cesar A.

    1. You have access
      Antiproliferation Activity of a Small Molecule Repressor of Liver Receptor Homolog 1
      Cesar A. Corzo, Yelenis Mari, Mi Ra Chang, Tanya Khan, Dana Kuruvilla, Philippe Nuhant, Naresh Kumar, Graham M. West, Derek R. Duckett, William R. Roush and Patrick R. Griffin
      Molecular Pharmacology February 2015, 87 (2) 296-304; DOI: https://doi.org/10.1124/mol.114.095554
  13. Cromie, K. D.

    1. You have access
      Potent and Efficacious Inhibition of CXCR2 Signaling by Biparatopic Nanobodies Combining Two Distinct Modes of Action
      M. E. Bradley, B. Dombrecht, J. Manini, J. Willis, D. Vlerick, S. De Taeye, K. Van den Heede, A. Roobrouck, E. Grot, T. C. Kent, T. Laeremans, S. Steffensen, G. Van Heeke, Z. Brown, S. J. Charlton and K. D. Cromie
      Molecular Pharmacology February 2015, 87 (2) 251-262; DOI: https://doi.org/10.1124/mol.114.094821
  14. Cuny, Hartmut

    1. You have access
      Novel Mechanism of Voltage-Gated N-type (Cav2.2) Calcium Channel Inhibition Revealed through α-Conotoxin Vc1.1 Activation of the GABAB Receptor
      Thuan G. Huynh, Hartmut Cuny, Paul A. Slesinger and David J. Adams
      Molecular Pharmacology February 2015, 87 (2) 240-250; DOI: https://doi.org/10.1124/mol.114.096156

D

  1. D’Amico, Massimo

    1. You have access
      New Pyrimido-Indole Compound CD-160130 Preferentially Inhibits the KV11.1B Isoform and Produces Antileukemic Effects without Cardiotoxicity
      Luca Gasparoli, Massimo D’Amico, Marika Masselli, Serena Pillozzi, Rachel Caves, Rawan Khuwaileh, Wolfgang Tiedke, Kenneth Mugridge, Alessandro Pratesi, John S. Mitcheson, Giuseppe Basso, Andrea Becchetti and Annarosa Arcangeli
      Molecular Pharmacology February 2015, 87 (2) 183-196; DOI: https://doi.org/10.1124/mol.114.094920
  2. Das, Swadesh K.

    1. You have access
      Reversing Translational Suppression and Induction of Toxicity in Pancreatic Cancer Cells Using a Chemoprevention Gene Therapy Approach
      Siddik Sarkar, Bridget A. Quinn, Xuening Shen, Paul Dent, Swadesh K. Das, Luni Emdad, Devanand Sarkar and Paul B. Fisher
      Molecular Pharmacology February 2015, 87 (2) 286-295; DOI: https://doi.org/10.1124/mol.114.094375
  3. Dent, Paul

    1. You have access
      Reversing Translational Suppression and Induction of Toxicity in Pancreatic Cancer Cells Using a Chemoprevention Gene Therapy Approach
      Siddik Sarkar, Bridget A. Quinn, Xuening Shen, Paul Dent, Swadesh K. Das, Luni Emdad, Devanand Sarkar and Paul B. Fisher
      Molecular Pharmacology February 2015, 87 (2) 286-295; DOI: https://doi.org/10.1124/mol.114.094375
  4. De Taeye, S.

    1. You have access
      Potent and Efficacious Inhibition of CXCR2 Signaling by Biparatopic Nanobodies Combining Two Distinct Modes of Action
      M. E. Bradley, B. Dombrecht, J. Manini, J. Willis, D. Vlerick, S. De Taeye, K. Van den Heede, A. Roobrouck, E. Grot, T. C. Kent, T. Laeremans, S. Steffensen, G. Van Heeke, Z. Brown, S. J. Charlton and K. D. Cromie
      Molecular Pharmacology February 2015, 87 (2) 251-262; DOI: https://doi.org/10.1124/mol.114.094821
  5. Díaz-de-Villegas, María D.

    1. You have access
      A Novel Pan-Negative-Gating Modulator of KCa2/3 Channels, Fluoro-Di-Benzoate, RA-2, Inhibits Endothelium-Derived Hyperpolarization–Type Relaxation in Coronary Artery and Produces Bradycardia In Vivo
      Aida Oliván-Viguera, Marta Sofía Valero, Nicole Coleman, Brandon M. Brown, Celia Laría, María Divina Murillo, José A. Gálvez, María D. Díaz-de-Villegas, Heike Wulff, Ramón Badorrey and Ralf Köhler
      Molecular Pharmacology February 2015, 87 (2) 338-348; DOI: https://doi.org/10.1124/mol.114.095745
  6. Diederich, Wibke E.

    1. You have access
      The Inverse Agonist DG172 Triggers a PPARβ/δ-Independent Myeloid Lineage Shift and Promotes GM-CSF/IL-4-Induced Dendritic Cell Differentiation
      Sonja Lieber, Frithjof Scheer, Florian Finkernagel, Wolfgang Meissner, Gavin Giehl, Cornelia Brendel, Wibke E. Diederich, Sabine Müller-Brüsselbach and Rolf Müller
      Molecular Pharmacology February 2015, 87 (2) 162-173; DOI: https://doi.org/10.1124/mol.114.094672
  7. Dillehay, Kelsey L.

    1. You have access
      A Peptide Mimicking a Region in Proliferating Cell Nuclear Antigen Specific to Key Protein Interactions Is Cytotoxic to Breast Cancer
      Shanna J. Smith, Long Gu, Elizabeth A. Phipps, Lacey E. Dobrolecki, Karla S. Mabrey, Pattie Gulley, Kelsey L. Dillehay, Zhongyun Dong, Gregg B. Fields, Yun-Ru Chen, David Ann, Robert J. Hickey and Linda H. Malkas
      Molecular Pharmacology February 2015, 87 (2) 263-276; DOI: https://doi.org/10.1124/mol.114.093211
  8. Divina Murillo, María

    1. You have access
      A Novel Pan-Negative-Gating Modulator of KCa2/3 Channels, Fluoro-Di-Benzoate, RA-2, Inhibits Endothelium-Derived Hyperpolarization–Type Relaxation in Coronary Artery and Produces Bradycardia In Vivo
      Aida Oliván-Viguera, Marta Sofía Valero, Nicole Coleman, Brandon M. Brown, Celia Laría, María Divina Murillo, José A. Gálvez, María D. Díaz-de-Villegas, Heike Wulff, Ramón Badorrey and Ralf Köhler
      Molecular Pharmacology February 2015, 87 (2) 338-348; DOI: https://doi.org/10.1124/mol.114.095745
  9. Dobrolecki, Lacey E.

    1. You have access
      A Peptide Mimicking a Region in Proliferating Cell Nuclear Antigen Specific to Key Protein Interactions Is Cytotoxic to Breast Cancer
      Shanna J. Smith, Long Gu, Elizabeth A. Phipps, Lacey E. Dobrolecki, Karla S. Mabrey, Pattie Gulley, Kelsey L. Dillehay, Zhongyun Dong, Gregg B. Fields, Yun-Ru Chen, David Ann, Robert J. Hickey and Linda H. Malkas
      Molecular Pharmacology February 2015, 87 (2) 263-276; DOI: https://doi.org/10.1124/mol.114.093211
  10. Domaoal, Robert A.

    1. You have access
      An Integrated Biological Approach to Guide the Development of Metal-Chelating Inhibitors of Influenza Virus PA Endonuclease
      Annelies Stevaert, Salvatore Nurra, Nicolino Pala, Mauro Carcelli, Dominga Rogolino, Caitlin Shepard, Robert A. Domaoal, Baek Kim, Mercedes Alfonso-Prieto, Salvatore A. E. Marras, Mario Sechi and Lieve Naesens
      Molecular Pharmacology February 2015, 87 (2) 323-337; DOI: https://doi.org/10.1124/mol.114.095588
  11. Dombrecht, B.

    1. You have access
      Potent and Efficacious Inhibition of CXCR2 Signaling by Biparatopic Nanobodies Combining Two Distinct Modes of Action
      M. E. Bradley, B. Dombrecht, J. Manini, J. Willis, D. Vlerick, S. De Taeye, K. Van den Heede, A. Roobrouck, E. Grot, T. C. Kent, T. Laeremans, S. Steffensen, G. Van Heeke, Z. Brown, S. J. Charlton and K. D. Cromie
      Molecular Pharmacology February 2015, 87 (2) 251-262; DOI: https://doi.org/10.1124/mol.114.094821
  12. Dong, Zhongyun

    1. You have access
      A Peptide Mimicking a Region in Proliferating Cell Nuclear Antigen Specific to Key Protein Interactions Is Cytotoxic to Breast Cancer
      Shanna J. Smith, Long Gu, Elizabeth A. Phipps, Lacey E. Dobrolecki, Karla S. Mabrey, Pattie Gulley, Kelsey L. Dillehay, Zhongyun Dong, Gregg B. Fields, Yun-Ru Chen, David Ann, Robert J. Hickey and Linda H. Malkas
      Molecular Pharmacology February 2015, 87 (2) 263-276; DOI: https://doi.org/10.1124/mol.114.093211
  13. Donnelly, Siobhan M.

    1. You have access
      Insulin-Like Growth Factor-1 Receptor Signaling Increases the Invasive Potential of Human Epidermal Growth Factor Receptor 2–Overexpressing Breast Cancer Cells via Src-Focal Adhesion Kinase and Forkhead Box Protein M1
      Eduardo Sanabria-Figueroa, Siobhan M. Donnelly, Kevin C. Foy, Meghan C. Buss, Robert C. Castellino, Elisavet Paplomata, Latonia Taliaferro-Smith, Pravin T.P. Kaumaya and Rita Nahta
      Molecular Pharmacology February 2015, 87 (2) 150-161; DOI: https://doi.org/10.1124/mol.114.095380
  14. Dryer, Stuart E.

    1. You have access
      RETRACTION: STAT3 Regulates Steady-State Expression of Synaptopodin in Cultured Mouse Podocytes
      Mousa Abkhezr and Stuart E. Dryer
      Molecular Pharmacology February 2015, 87 (2) 231-239; DOI: https://doi.org/10.1124/mol.114.094508
  15. Du, Fang

    1. You have access
      Reporting Sodium Channel Activity Using Calcium Flux: Pharmacological Promiscuity of Cardiac Nav1.5
      Hongkang Zhang, Beiyan Zou, Fang Du, Kaiping Xu and Min Li
      Molecular Pharmacology February 2015, 87 (2) 207-217; DOI: https://doi.org/10.1124/mol.114.094789
  16. Duckett, Derek R.

    1. You have access
      Antiproliferation Activity of a Small Molecule Repressor of Liver Receptor Homolog 1
      Cesar A. Corzo, Yelenis Mari, Mi Ra Chang, Tanya Khan, Dana Kuruvilla, Philippe Nuhant, Naresh Kumar, Graham M. West, Derek R. Duckett, William R. Roush and Patrick R. Griffin
      Molecular Pharmacology February 2015, 87 (2) 296-304; DOI: https://doi.org/10.1124/mol.114.095554

E

  1. Emdad, Luni

    1. You have access
      Reversing Translational Suppression and Induction of Toxicity in Pancreatic Cancer Cells Using a Chemoprevention Gene Therapy Approach
      Siddik Sarkar, Bridget A. Quinn, Xuening Shen, Paul Dent, Swadesh K. Das, Luni Emdad, Devanand Sarkar and Paul B. Fisher
      Molecular Pharmacology February 2015, 87 (2) 286-295; DOI: https://doi.org/10.1124/mol.114.094375

F

  1. Fields, Gregg B.

    1. You have access
      A Peptide Mimicking a Region in Proliferating Cell Nuclear Antigen Specific to Key Protein Interactions Is Cytotoxic to Breast Cancer
      Shanna J. Smith, Long Gu, Elizabeth A. Phipps, Lacey E. Dobrolecki, Karla S. Mabrey, Pattie Gulley, Kelsey L. Dillehay, Zhongyun Dong, Gregg B. Fields, Yun-Ru Chen, David Ann, Robert J. Hickey and Linda H. Malkas
      Molecular Pharmacology February 2015, 87 (2) 263-276; DOI: https://doi.org/10.1124/mol.114.093211
  2. Finkernagel, Florian

    1. You have access
      The Inverse Agonist DG172 Triggers a PPARβ/δ-Independent Myeloid Lineage Shift and Promotes GM-CSF/IL-4-Induced Dendritic Cell Differentiation
      Sonja Lieber, Frithjof Scheer, Florian Finkernagel, Wolfgang Meissner, Gavin Giehl, Cornelia Brendel, Wibke E. Diederich, Sabine Müller-Brüsselbach and Rolf Müller
      Molecular Pharmacology February 2015, 87 (2) 162-173; DOI: https://doi.org/10.1124/mol.114.094672
  3. Fisher, Paul B.

    1. You have access
      Reversing Translational Suppression and Induction of Toxicity in Pancreatic Cancer Cells Using a Chemoprevention Gene Therapy Approach
      Siddik Sarkar, Bridget A. Quinn, Xuening Shen, Paul Dent, Swadesh K. Das, Luni Emdad, Devanand Sarkar and Paul B. Fisher
      Molecular Pharmacology February 2015, 87 (2) 286-295; DOI: https://doi.org/10.1124/mol.114.094375
  4. Foy, Kevin C.

    1. You have access
      Insulin-Like Growth Factor-1 Receptor Signaling Increases the Invasive Potential of Human Epidermal Growth Factor Receptor 2–Overexpressing Breast Cancer Cells via Src-Focal Adhesion Kinase and Forkhead Box Protein M1
      Eduardo Sanabria-Figueroa, Siobhan M. Donnelly, Kevin C. Foy, Meghan C. Buss, Robert C. Castellino, Elisavet Paplomata, Latonia Taliaferro-Smith, Pravin T.P. Kaumaya and Rita Nahta
      Molecular Pharmacology February 2015, 87 (2) 150-161; DOI: https://doi.org/10.1124/mol.114.095380

G

  1. Gálvez, José A.

    1. You have access
      A Novel Pan-Negative-Gating Modulator of KCa2/3 Channels, Fluoro-Di-Benzoate, RA-2, Inhibits Endothelium-Derived Hyperpolarization–Type Relaxation in Coronary Artery and Produces Bradycardia In Vivo
      Aida Oliván-Viguera, Marta Sofía Valero, Nicole Coleman, Brandon M. Brown, Celia Laría, María Divina Murillo, José A. Gálvez, María D. Díaz-de-Villegas, Heike Wulff, Ramón Badorrey and Ralf Köhler
      Molecular Pharmacology February 2015, 87 (2) 338-348; DOI: https://doi.org/10.1124/mol.114.095745
  2. Gasparoli, Luca

    1. You have access
      New Pyrimido-Indole Compound CD-160130 Preferentially Inhibits the KV11.1B Isoform and Produces Antileukemic Effects without Cardiotoxicity
      Luca Gasparoli, Massimo D’Amico, Marika Masselli, Serena Pillozzi, Rachel Caves, Rawan Khuwaileh, Wolfgang Tiedke, Kenneth Mugridge, Alessandro Pratesi, John S. Mitcheson, Giuseppe Basso, Andrea Becchetti and Annarosa Arcangeli
      Molecular Pharmacology February 2015, 87 (2) 183-196; DOI: https://doi.org/10.1124/mol.114.094920
  3. Giehl, Gavin

    1. You have access
      The Inverse Agonist DG172 Triggers a PPARβ/δ-Independent Myeloid Lineage Shift and Promotes GM-CSF/IL-4-Induced Dendritic Cell Differentiation
      Sonja Lieber, Frithjof Scheer, Florian Finkernagel, Wolfgang Meissner, Gavin Giehl, Cornelia Brendel, Wibke E. Diederich, Sabine Müller-Brüsselbach and Rolf Müller
      Molecular Pharmacology February 2015, 87 (2) 162-173; DOI: https://doi.org/10.1124/mol.114.094672
  4. Griffin, Patrick R.

    1. You have access
      Antiproliferation Activity of a Small Molecule Repressor of Liver Receptor Homolog 1
      Cesar A. Corzo, Yelenis Mari, Mi Ra Chang, Tanya Khan, Dana Kuruvilla, Philippe Nuhant, Naresh Kumar, Graham M. West, Derek R. Duckett, William R. Roush and Patrick R. Griffin
      Molecular Pharmacology February 2015, 87 (2) 296-304; DOI: https://doi.org/10.1124/mol.114.095554
  5. Grot, E.

    1. You have access
      Potent and Efficacious Inhibition of CXCR2 Signaling by Biparatopic Nanobodies Combining Two Distinct Modes of Action
      M. E. Bradley, B. Dombrecht, J. Manini, J. Willis, D. Vlerick, S. De Taeye, K. Van den Heede, A. Roobrouck, E. Grot, T. C. Kent, T. Laeremans, S. Steffensen, G. Van Heeke, Z. Brown, S. J. Charlton and K. D. Cromie
      Molecular Pharmacology February 2015, 87 (2) 251-262; DOI: https://doi.org/10.1124/mol.114.094821
  6. Gu, Long

    1. You have access
      A Peptide Mimicking a Region in Proliferating Cell Nuclear Antigen Specific to Key Protein Interactions Is Cytotoxic to Breast Cancer
      Shanna J. Smith, Long Gu, Elizabeth A. Phipps, Lacey E. Dobrolecki, Karla S. Mabrey, Pattie Gulley, Kelsey L. Dillehay, Zhongyun Dong, Gregg B. Fields, Yun-Ru Chen, David Ann, Robert J. Hickey and Linda H. Malkas
      Molecular Pharmacology February 2015, 87 (2) 263-276; DOI: https://doi.org/10.1124/mol.114.093211
  7. Gulley, Pattie

    1. You have access
      A Peptide Mimicking a Region in Proliferating Cell Nuclear Antigen Specific to Key Protein Interactions Is Cytotoxic to Breast Cancer
      Shanna J. Smith, Long Gu, Elizabeth A. Phipps, Lacey E. Dobrolecki, Karla S. Mabrey, Pattie Gulley, Kelsey L. Dillehay, Zhongyun Dong, Gregg B. Fields, Yun-Ru Chen, David Ann, Robert J. Hickey and Linda H. Malkas
      Molecular Pharmacology February 2015, 87 (2) 263-276; DOI: https://doi.org/10.1124/mol.114.093211
  8. Gutiérrez-de-Terán, Hugo

    1. You have access
      Sodium Ion Binding Pocket Mutations and Adenosine A2A Receptor Function
      Arnault Massink, Hugo Gutiérrez-de-Terán, Eelke B. Lenselink, Natalia V. Ortiz Zacarías, Lizi Xia, Laura H. Heitman, Vsevolod Katritch, Raymond C. Stevens and Adriaan P. IJzerman
      Molecular Pharmacology February 2015, 87 (2) 305-313; DOI: https://doi.org/10.1124/mol.114.095737

H

  1. Hashimoto, Hana

    1. You have access
      Modulation of Peroxisome Proliferator-Activated Receptor-α Activity by Bile Acids Causes Circadian Changes in the Intestinal Expression of Octn1/Slc22a4 in Mice
      Erika Wada, Satoru Koyanagi, Naoki Kusunose, Takahiro Akamine, Hiroaki Masui, Hana Hashimoto, Naoya Matsunaga and Shigehiro Ohdo
      Molecular Pharmacology February 2015, 87 (2) 314-322; DOI: https://doi.org/10.1124/mol.114.094979
  2. Heitman, Laura H.

    1. You have access
      Sodium Ion Binding Pocket Mutations and Adenosine A2A Receptor Function
      Arnault Massink, Hugo Gutiérrez-de-Terán, Eelke B. Lenselink, Natalia V. Ortiz Zacarías, Lizi Xia, Laura H. Heitman, Vsevolod Katritch, Raymond C. Stevens and Adriaan P. IJzerman
      Molecular Pharmacology February 2015, 87 (2) 305-313; DOI: https://doi.org/10.1124/mol.114.095737
  3. Hellmich, Mark R.

    1. You have access
      Pharmacological Inhibition and Genetic Knockdown of Exchange Protein Directly Activated by cAMP 1 Reduce Pancreatic Cancer Metastasis In Vivo
      Muayad Almahariq, Celia Chao, Fang C. Mei, Mark R. Hellmich, Igor Patrikeev, Massoud Motamedi and Xiaodong Cheng
      Molecular Pharmacology February 2015, 87 (2) 142-149; DOI: https://doi.org/10.1124/mol.114.095158
  4. Hickey, Robert J.

    1. You have access
      A Peptide Mimicking a Region in Proliferating Cell Nuclear Antigen Specific to Key Protein Interactions Is Cytotoxic to Breast Cancer
      Shanna J. Smith, Long Gu, Elizabeth A. Phipps, Lacey E. Dobrolecki, Karla S. Mabrey, Pattie Gulley, Kelsey L. Dillehay, Zhongyun Dong, Gregg B. Fields, Yun-Ru Chen, David Ann, Robert J. Hickey and Linda H. Malkas
      Molecular Pharmacology February 2015, 87 (2) 263-276; DOI: https://doi.org/10.1124/mol.114.093211
  5. Honda, Takeshi

    1. You have access
      Signaling Mechanism Underlying the Promotion of Keratinocyte Migration by Angiotensin II
      Hiroki Sakai, Kenji Matsuura, Yoshie Tanaka, Takeshi Honda, Teruo Nishida and Makoto Inui
      Molecular Pharmacology February 2015, 87 (2) 277-285; DOI: https://doi.org/10.1124/mol.114.096461
  6. Hsiao, Nai-Wan

    1. You have access
      Phage Display–Mediated Discovery of Novel Tyrosinase-Targeting Tetrapeptide Inhibitors Reveals the Significance of N-Terminal Preference of Cysteine Residues and Their Functional Sulfur Atom
      Yu-Ching Lee, Nai-Wan Hsiao, Tien-Sheng Tseng, Wang-Chuan Chen, Hui-Hsiung Lin, Sy-Jye Leu, Ei-Wen Yang and Keng-Chang Tsai
      Molecular Pharmacology February 2015, 87 (2) 218-230; DOI: https://doi.org/10.1124/mol.114.094185
  7. Hu, Liping

    1. You have access
      An Overview of Hedgehog Signaling in Fibrosis
      Liping Hu, Xiangyang Lin, Hong Lu, Bicheng Chen and Yongheng Bai
      Molecular Pharmacology February 2015, 87 (2) 174-182; DOI: https://doi.org/10.1124/mol.114.095141
  8. Hurst, Dow P.

    1. You have access
      (4-(Bis(4-Fluorophenyl)Methyl)Piperazin-1-yl)(Cyclohexyl)Methanone Hydrochloride (LDK1229): A New Cannabinoid CB1 Receptor Inverse Agonist from the Class of Benzhydryl Piperazine Analogs
      Mariam M. Mahmoud, Teresa Olszewska, Hui Liu, Derek M. Shore, Dow P. Hurst, Patricia H. Reggio, Dai Lu and Debra A. Kendall
      Molecular Pharmacology February 2015, 87 (2) 197-206; DOI: https://doi.org/10.1124/mol.114.095471
  9. Huynh, Thuan G.

    1. You have access
      Novel Mechanism of Voltage-Gated N-type (Cav2.2) Calcium Channel Inhibition Revealed through α-Conotoxin Vc1.1 Activation of the GABAB Receptor
      Thuan G. Huynh, Hartmut Cuny, Paul A. Slesinger and David J. Adams
      Molecular Pharmacology February 2015, 87 (2) 240-250; DOI: https://doi.org/10.1124/mol.114.096156

I

  1. IJzerman, Adriaan P.

    1. You have access
      Sodium Ion Binding Pocket Mutations and Adenosine A2A Receptor Function
      Arnault Massink, Hugo Gutiérrez-de-Terán, Eelke B. Lenselink, Natalia V. Ortiz Zacarías, Lizi Xia, Laura H. Heitman, Vsevolod Katritch, Raymond C. Stevens and Adriaan P. IJzerman
      Molecular Pharmacology February 2015, 87 (2) 305-313; DOI: https://doi.org/10.1124/mol.114.095737
  2. Inui, Makoto

    1. You have access
      Signaling Mechanism Underlying the Promotion of Keratinocyte Migration by Angiotensin II
      Hiroki Sakai, Kenji Matsuura, Yoshie Tanaka, Takeshi Honda, Teruo Nishida and Makoto Inui
      Molecular Pharmacology February 2015, 87 (2) 277-285; DOI: https://doi.org/10.1124/mol.114.096461

K

  1. Katritch, Vsevolod

    1. You have access
      Sodium Ion Binding Pocket Mutations and Adenosine A2A Receptor Function
      Arnault Massink, Hugo Gutiérrez-de-Terán, Eelke B. Lenselink, Natalia V. Ortiz Zacarías, Lizi Xia, Laura H. Heitman, Vsevolod Katritch, Raymond C. Stevens and Adriaan P. IJzerman
      Molecular Pharmacology February 2015, 87 (2) 305-313; DOI: https://doi.org/10.1124/mol.114.095737
  2. Kaumaya, Pravin T.P.

    1. You have access
      Insulin-Like Growth Factor-1 Receptor Signaling Increases the Invasive Potential of Human Epidermal Growth Factor Receptor 2–Overexpressing Breast Cancer Cells via Src-Focal Adhesion Kinase and Forkhead Box Protein M1
      Eduardo Sanabria-Figueroa, Siobhan M. Donnelly, Kevin C. Foy, Meghan C. Buss, Robert C. Castellino, Elisavet Paplomata, Latonia Taliaferro-Smith, Pravin T.P. Kaumaya and Rita Nahta
      Molecular Pharmacology February 2015, 87 (2) 150-161; DOI: https://doi.org/10.1124/mol.114.095380
  3. Kendall, Debra A.

    1. You have access
      (4-(Bis(4-Fluorophenyl)Methyl)Piperazin-1-yl)(Cyclohexyl)Methanone Hydrochloride (LDK1229): A New Cannabinoid CB1 Receptor Inverse Agonist from the Class of Benzhydryl Piperazine Analogs
      Mariam M. Mahmoud, Teresa Olszewska, Hui Liu, Derek M. Shore, Dow P. Hurst, Patricia H. Reggio, Dai Lu and Debra A. Kendall
      Molecular Pharmacology February 2015, 87 (2) 197-206; DOI: https://doi.org/10.1124/mol.114.095471
  4. Kent, T. C.

    1. You have access
      Potent and Efficacious Inhibition of CXCR2 Signaling by Biparatopic Nanobodies Combining Two Distinct Modes of Action
      M. E. Bradley, B. Dombrecht, J. Manini, J. Willis, D. Vlerick, S. De Taeye, K. Van den Heede, A. Roobrouck, E. Grot, T. C. Kent, T. Laeremans, S. Steffensen, G. Van Heeke, Z. Brown, S. J. Charlton and K. D. Cromie
      Molecular Pharmacology February 2015, 87 (2) 251-262; DOI: https://doi.org/10.1124/mol.114.094821
  5. Khan, Tanya

    1. You have access
      Antiproliferation Activity of a Small Molecule Repressor of Liver Receptor Homolog 1
      Cesar A. Corzo, Yelenis Mari, Mi Ra Chang, Tanya Khan, Dana Kuruvilla, Philippe Nuhant, Naresh Kumar, Graham M. West, Derek R. Duckett, William R. Roush and Patrick R. Griffin
      Molecular Pharmacology February 2015, 87 (2) 296-304; DOI: https://doi.org/10.1124/mol.114.095554
  6. Khuwaileh, Rawan

    1. You have access
      New Pyrimido-Indole Compound CD-160130 Preferentially Inhibits the KV11.1B Isoform and Produces Antileukemic Effects without Cardiotoxicity
      Luca Gasparoli, Massimo D’Amico, Marika Masselli, Serena Pillozzi, Rachel Caves, Rawan Khuwaileh, Wolfgang Tiedke, Kenneth Mugridge, Alessandro Pratesi, John S. Mitcheson, Giuseppe Basso, Andrea Becchetti and Annarosa Arcangeli
      Molecular Pharmacology February 2015, 87 (2) 183-196; DOI: https://doi.org/10.1124/mol.114.094920
  7. Kim, Baek

    1. You have access
      An Integrated Biological Approach to Guide the Development of Metal-Chelating Inhibitors of Influenza Virus PA Endonuclease
      Annelies Stevaert, Salvatore Nurra, Nicolino Pala, Mauro Carcelli, Dominga Rogolino, Caitlin Shepard, Robert A. Domaoal, Baek Kim, Mercedes Alfonso-Prieto, Salvatore A. E. Marras, Mario Sechi and Lieve Naesens
      Molecular Pharmacology February 2015, 87 (2) 323-337; DOI: https://doi.org/10.1124/mol.114.095588
  8. Köhler, Ralf

    1. You have access
      A Novel Pan-Negative-Gating Modulator of KCa2/3 Channels, Fluoro-Di-Benzoate, RA-2, Inhibits Endothelium-Derived Hyperpolarization–Type Relaxation in Coronary Artery and Produces Bradycardia In Vivo
      Aida Oliván-Viguera, Marta Sofía Valero, Nicole Coleman, Brandon M. Brown, Celia Laría, María Divina Murillo, José A. Gálvez, María D. Díaz-de-Villegas, Heike Wulff, Ramón Badorrey and Ralf Köhler
      Molecular Pharmacology February 2015, 87 (2) 338-348; DOI: https://doi.org/10.1124/mol.114.095745
  9. Koyanagi, Satoru

    1. You have access
      Modulation of Peroxisome Proliferator-Activated Receptor-α Activity by Bile Acids Causes Circadian Changes in the Intestinal Expression of Octn1/Slc22a4 in Mice
      Erika Wada, Satoru Koyanagi, Naoki Kusunose, Takahiro Akamine, Hiroaki Masui, Hana Hashimoto, Naoya Matsunaga and Shigehiro Ohdo
      Molecular Pharmacology February 2015, 87 (2) 314-322; DOI: https://doi.org/10.1124/mol.114.094979
  10. Krasel, Cornelius

    1. You have access
      Engineered Hyperphosphorylation of the β2-Adrenoceptor Prolongs Arrestin-3 Binding and Induces Arrestin Internalization
      Diana Zindel, Adrian J. Butcher, Suleiman Al-Sabah, Peter Lanzerstorfer, Julian Weghuber, Andrew B. Tobin, Moritz Bünemann and Cornelius Krasel
      Molecular Pharmacology February 2015, 87 (2) 349-362; DOI: https://doi.org/10.1124/mol.114.095422
  11. Kumar, Naresh

    1. You have access
      Antiproliferation Activity of a Small Molecule Repressor of Liver Receptor Homolog 1
      Cesar A. Corzo, Yelenis Mari, Mi Ra Chang, Tanya Khan, Dana Kuruvilla, Philippe Nuhant, Naresh Kumar, Graham M. West, Derek R. Duckett, William R. Roush and Patrick R. Griffin
      Molecular Pharmacology February 2015, 87 (2) 296-304; DOI: https://doi.org/10.1124/mol.114.095554
  12. Kuruvilla, Dana

    1. You have access
      Antiproliferation Activity of a Small Molecule Repressor of Liver Receptor Homolog 1
      Cesar A. Corzo, Yelenis Mari, Mi Ra Chang, Tanya Khan, Dana Kuruvilla, Philippe Nuhant, Naresh Kumar, Graham M. West, Derek R. Duckett, William R. Roush and Patrick R. Griffin
      Molecular Pharmacology February 2015, 87 (2) 296-304; DOI: https://doi.org/10.1124/mol.114.095554
  13. Kusunose, Naoki

    1. You have access
      Modulation of Peroxisome Proliferator-Activated Receptor-α Activity by Bile Acids Causes Circadian Changes in the Intestinal Expression of Octn1/Slc22a4 in Mice
      Erika Wada, Satoru Koyanagi, Naoki Kusunose, Takahiro Akamine, Hiroaki Masui, Hana Hashimoto, Naoya Matsunaga and Shigehiro Ohdo
      Molecular Pharmacology February 2015, 87 (2) 314-322; DOI: https://doi.org/10.1124/mol.114.094979

L

  1. Laeremans, T.

    1. You have access
      Potent and Efficacious Inhibition of CXCR2 Signaling by Biparatopic Nanobodies Combining Two Distinct Modes of Action
      M. E. Bradley, B. Dombrecht, J. Manini, J. Willis, D. Vlerick, S. De Taeye, K. Van den Heede, A. Roobrouck, E. Grot, T. C. Kent, T. Laeremans, S. Steffensen, G. Van Heeke, Z. Brown, S. J. Charlton and K. D. Cromie
      Molecular Pharmacology February 2015, 87 (2) 251-262; DOI: https://doi.org/10.1124/mol.114.094821
  2. Lanzerstorfer, Peter

    1. You have access
      Engineered Hyperphosphorylation of the β2-Adrenoceptor Prolongs Arrestin-3 Binding and Induces Arrestin Internalization
      Diana Zindel, Adrian J. Butcher, Suleiman Al-Sabah, Peter Lanzerstorfer, Julian Weghuber, Andrew B. Tobin, Moritz Bünemann and Cornelius Krasel
      Molecular Pharmacology February 2015, 87 (2) 349-362; DOI: https://doi.org/10.1124/mol.114.095422
  3. Laría, Celia

    1. You have access
      A Novel Pan-Negative-Gating Modulator of KCa2/3 Channels, Fluoro-Di-Benzoate, RA-2, Inhibits Endothelium-Derived Hyperpolarization–Type Relaxation in Coronary Artery and Produces Bradycardia In Vivo
      Aida Oliván-Viguera, Marta Sofía Valero, Nicole Coleman, Brandon M. Brown, Celia Laría, María Divina Murillo, José A. Gálvez, María D. Díaz-de-Villegas, Heike Wulff, Ramón Badorrey and Ralf Köhler
      Molecular Pharmacology February 2015, 87 (2) 338-348; DOI: https://doi.org/10.1124/mol.114.095745
  4. Lee, Yu-Ching

    1. You have access
      Phage Display–Mediated Discovery of Novel Tyrosinase-Targeting Tetrapeptide Inhibitors Reveals the Significance of N-Terminal Preference of Cysteine Residues and Their Functional Sulfur Atom
      Yu-Ching Lee, Nai-Wan Hsiao, Tien-Sheng Tseng, Wang-Chuan Chen, Hui-Hsiung Lin, Sy-Jye Leu, Ei-Wen Yang and Keng-Chang Tsai
      Molecular Pharmacology February 2015, 87 (2) 218-230; DOI: https://doi.org/10.1124/mol.114.094185
  5. Lenselink, Eelke B.

    1. You have access
      Sodium Ion Binding Pocket Mutations and Adenosine A2A Receptor Function
      Arnault Massink, Hugo Gutiérrez-de-Terán, Eelke B. Lenselink, Natalia V. Ortiz Zacarías, Lizi Xia, Laura H. Heitman, Vsevolod Katritch, Raymond C. Stevens and Adriaan P. IJzerman
      Molecular Pharmacology February 2015, 87 (2) 305-313; DOI: https://doi.org/10.1124/mol.114.095737
  6. Leu, Sy-Jye

    1. You have access
      Phage Display–Mediated Discovery of Novel Tyrosinase-Targeting Tetrapeptide Inhibitors Reveals the Significance of N-Terminal Preference of Cysteine Residues and Their Functional Sulfur Atom
      Yu-Ching Lee, Nai-Wan Hsiao, Tien-Sheng Tseng, Wang-Chuan Chen, Hui-Hsiung Lin, Sy-Jye Leu, Ei-Wen Yang and Keng-Chang Tsai
      Molecular Pharmacology February 2015, 87 (2) 218-230; DOI: https://doi.org/10.1124/mol.114.094185
  7. Li, Min

    1. You have access
      Reporting Sodium Channel Activity Using Calcium Flux: Pharmacological Promiscuity of Cardiac Nav1.5
      Hongkang Zhang, Beiyan Zou, Fang Du, Kaiping Xu and Min Li
      Molecular Pharmacology February 2015, 87 (2) 207-217; DOI: https://doi.org/10.1124/mol.114.094789
  8. Lieber, Sonja

    1. You have access
      The Inverse Agonist DG172 Triggers a PPARβ/δ-Independent Myeloid Lineage Shift and Promotes GM-CSF/IL-4-Induced Dendritic Cell Differentiation
      Sonja Lieber, Frithjof Scheer, Florian Finkernagel, Wolfgang Meissner, Gavin Giehl, Cornelia Brendel, Wibke E. Diederich, Sabine Müller-Brüsselbach and Rolf Müller
      Molecular Pharmacology February 2015, 87 (2) 162-173; DOI: https://doi.org/10.1124/mol.114.094672
  9. Lin, Hui-Hsiung

    1. You have access
      Phage Display–Mediated Discovery of Novel Tyrosinase-Targeting Tetrapeptide Inhibitors Reveals the Significance of N-Terminal Preference of Cysteine Residues and Their Functional Sulfur Atom
      Yu-Ching Lee, Nai-Wan Hsiao, Tien-Sheng Tseng, Wang-Chuan Chen, Hui-Hsiung Lin, Sy-Jye Leu, Ei-Wen Yang and Keng-Chang Tsai
      Molecular Pharmacology February 2015, 87 (2) 218-230; DOI: https://doi.org/10.1124/mol.114.094185
  10. Lin, Xiangyang

    1. You have access
      An Overview of Hedgehog Signaling in Fibrosis
      Liping Hu, Xiangyang Lin, Hong Lu, Bicheng Chen and Yongheng Bai
      Molecular Pharmacology February 2015, 87 (2) 174-182; DOI: https://doi.org/10.1124/mol.114.095141
  11. Liu, Hui

    1. You have access
      (4-(Bis(4-Fluorophenyl)Methyl)Piperazin-1-yl)(Cyclohexyl)Methanone Hydrochloride (LDK1229): A New Cannabinoid CB1 Receptor Inverse Agonist from the Class of Benzhydryl Piperazine Analogs
      Mariam M. Mahmoud, Teresa Olszewska, Hui Liu, Derek M. Shore, Dow P. Hurst, Patricia H. Reggio, Dai Lu and Debra A. Kendall
      Molecular Pharmacology February 2015, 87 (2) 197-206; DOI: https://doi.org/10.1124/mol.114.095471
  12. Lu, Dai

    1. You have access
      (4-(Bis(4-Fluorophenyl)Methyl)Piperazin-1-yl)(Cyclohexyl)Methanone Hydrochloride (LDK1229): A New Cannabinoid CB1 Receptor Inverse Agonist from the Class of Benzhydryl Piperazine Analogs
      Mariam M. Mahmoud, Teresa Olszewska, Hui Liu, Derek M. Shore, Dow P. Hurst, Patricia H. Reggio, Dai Lu and Debra A. Kendall
      Molecular Pharmacology February 2015, 87 (2) 197-206; DOI: https://doi.org/10.1124/mol.114.095471
  13. Lu, Hong

    1. You have access
      An Overview of Hedgehog Signaling in Fibrosis
      Liping Hu, Xiangyang Lin, Hong Lu, Bicheng Chen and Yongheng Bai
      Molecular Pharmacology February 2015, 87 (2) 174-182; DOI: https://doi.org/10.1124/mol.114.095141

M

  1. Mabrey, Karla S.

    1. You have access
      A Peptide Mimicking a Region in Proliferating Cell Nuclear Antigen Specific to Key Protein Interactions Is Cytotoxic to Breast Cancer
      Shanna J. Smith, Long Gu, Elizabeth A. Phipps, Lacey E. Dobrolecki, Karla S. Mabrey, Pattie Gulley, Kelsey L. Dillehay, Zhongyun Dong, Gregg B. Fields, Yun-Ru Chen, David Ann, Robert J. Hickey and Linda H. Malkas
      Molecular Pharmacology February 2015, 87 (2) 263-276; DOI: https://doi.org/10.1124/mol.114.093211
  2. Mahmoud, Mariam M.

    1. You have access
      (4-(Bis(4-Fluorophenyl)Methyl)Piperazin-1-yl)(Cyclohexyl)Methanone Hydrochloride (LDK1229): A New Cannabinoid CB1 Receptor Inverse Agonist from the Class of Benzhydryl Piperazine Analogs
      Mariam M. Mahmoud, Teresa Olszewska, Hui Liu, Derek M. Shore, Dow P. Hurst, Patricia H. Reggio, Dai Lu and Debra A. Kendall
      Molecular Pharmacology February 2015, 87 (2) 197-206; DOI: https://doi.org/10.1124/mol.114.095471
  3. Malkas, Linda H.

    1. You have access
      A Peptide Mimicking a Region in Proliferating Cell Nuclear Antigen Specific to Key Protein Interactions Is Cytotoxic to Breast Cancer
      Shanna J. Smith, Long Gu, Elizabeth A. Phipps, Lacey E. Dobrolecki, Karla S. Mabrey, Pattie Gulley, Kelsey L. Dillehay, Zhongyun Dong, Gregg B. Fields, Yun-Ru Chen, David Ann, Robert J. Hickey and Linda H. Malkas
      Molecular Pharmacology February 2015, 87 (2) 263-276; DOI: https://doi.org/10.1124/mol.114.093211
  4. Manini, J.

    1. You have access
      Potent and Efficacious Inhibition of CXCR2 Signaling by Biparatopic Nanobodies Combining Two Distinct Modes of Action
      M. E. Bradley, B. Dombrecht, J. Manini, J. Willis, D. Vlerick, S. De Taeye, K. Van den Heede, A. Roobrouck, E. Grot, T. C. Kent, T. Laeremans, S. Steffensen, G. Van Heeke, Z. Brown, S. J. Charlton and K. D. Cromie
      Molecular Pharmacology February 2015, 87 (2) 251-262; DOI: https://doi.org/10.1124/mol.114.094821
  5. Mari, Yelenis

    1. You have access
      Antiproliferation Activity of a Small Molecule Repressor of Liver Receptor Homolog 1
      Cesar A. Corzo, Yelenis Mari, Mi Ra Chang, Tanya Khan, Dana Kuruvilla, Philippe Nuhant, Naresh Kumar, Graham M. West, Derek R. Duckett, William R. Roush and Patrick R. Griffin
      Molecular Pharmacology February 2015, 87 (2) 296-304; DOI: https://doi.org/10.1124/mol.114.095554
  6. Marras, Salvatore A. E.

    1. You have access
      An Integrated Biological Approach to Guide the Development of Metal-Chelating Inhibitors of Influenza Virus PA Endonuclease
      Annelies Stevaert, Salvatore Nurra, Nicolino Pala, Mauro Carcelli, Dominga Rogolino, Caitlin Shepard, Robert A. Domaoal, Baek Kim, Mercedes Alfonso-Prieto, Salvatore A. E. Marras, Mario Sechi and Lieve Naesens
      Molecular Pharmacology February 2015, 87 (2) 323-337; DOI: https://doi.org/10.1124/mol.114.095588
  7. Masselli, Marika

    1. You have access
      New Pyrimido-Indole Compound CD-160130 Preferentially Inhibits the KV11.1B Isoform and Produces Antileukemic Effects without Cardiotoxicity
      Luca Gasparoli, Massimo D’Amico, Marika Masselli, Serena Pillozzi, Rachel Caves, Rawan Khuwaileh, Wolfgang Tiedke, Kenneth Mugridge, Alessandro Pratesi, John S. Mitcheson, Giuseppe Basso, Andrea Becchetti and Annarosa Arcangeli
      Molecular Pharmacology February 2015, 87 (2) 183-196; DOI: https://doi.org/10.1124/mol.114.094920
  8. Massink, Arnault

    1. You have access
      Sodium Ion Binding Pocket Mutations and Adenosine A2A Receptor Function
      Arnault Massink, Hugo Gutiérrez-de-Terán, Eelke B. Lenselink, Natalia V. Ortiz Zacarías, Lizi Xia, Laura H. Heitman, Vsevolod Katritch, Raymond C. Stevens and Adriaan P. IJzerman
      Molecular Pharmacology February 2015, 87 (2) 305-313; DOI: https://doi.org/10.1124/mol.114.095737
  9. Masui, Hiroaki

    1. You have access
      Modulation of Peroxisome Proliferator-Activated Receptor-α Activity by Bile Acids Causes Circadian Changes in the Intestinal Expression of Octn1/Slc22a4 in Mice
      Erika Wada, Satoru Koyanagi, Naoki Kusunose, Takahiro Akamine, Hiroaki Masui, Hana Hashimoto, Naoya Matsunaga and Shigehiro Ohdo
      Molecular Pharmacology February 2015, 87 (2) 314-322; DOI: https://doi.org/10.1124/mol.114.094979
  10. Matsunaga, Naoya

    1. You have access
      Modulation of Peroxisome Proliferator-Activated Receptor-α Activity by Bile Acids Causes Circadian Changes in the Intestinal Expression of Octn1/Slc22a4 in Mice
      Erika Wada, Satoru Koyanagi, Naoki Kusunose, Takahiro Akamine, Hiroaki Masui, Hana Hashimoto, Naoya Matsunaga and Shigehiro Ohdo
      Molecular Pharmacology February 2015, 87 (2) 314-322; DOI: https://doi.org/10.1124/mol.114.094979
  11. Matsuura, Kenji

    1. You have access
      Signaling Mechanism Underlying the Promotion of Keratinocyte Migration by Angiotensin II
      Hiroki Sakai, Kenji Matsuura, Yoshie Tanaka, Takeshi Honda, Teruo Nishida and Makoto Inui
      Molecular Pharmacology February 2015, 87 (2) 277-285; DOI: https://doi.org/10.1124/mol.114.096461
  12. Mei, Fang C.

    1. You have access
      Pharmacological Inhibition and Genetic Knockdown of Exchange Protein Directly Activated by cAMP 1 Reduce Pancreatic Cancer Metastasis In Vivo
      Muayad Almahariq, Celia Chao, Fang C. Mei, Mark R. Hellmich, Igor Patrikeev, Massoud Motamedi and Xiaodong Cheng
      Molecular Pharmacology February 2015, 87 (2) 142-149; DOI: https://doi.org/10.1124/mol.114.095158
  13. Meissner, Wolfgang

    1. You have access
      The Inverse Agonist DG172 Triggers a PPARβ/δ-Independent Myeloid Lineage Shift and Promotes GM-CSF/IL-4-Induced Dendritic Cell Differentiation
      Sonja Lieber, Frithjof Scheer, Florian Finkernagel, Wolfgang Meissner, Gavin Giehl, Cornelia Brendel, Wibke E. Diederich, Sabine Müller-Brüsselbach and Rolf Müller
      Molecular Pharmacology February 2015, 87 (2) 162-173; DOI: https://doi.org/10.1124/mol.114.094672
  14. Mitcheson, John S.

    1. You have access
      New Pyrimido-Indole Compound CD-160130 Preferentially Inhibits the KV11.1B Isoform and Produces Antileukemic Effects without Cardiotoxicity
      Luca Gasparoli, Massimo D’Amico, Marika Masselli, Serena Pillozzi, Rachel Caves, Rawan Khuwaileh, Wolfgang Tiedke, Kenneth Mugridge, Alessandro Pratesi, John S. Mitcheson, Giuseppe Basso, Andrea Becchetti and Annarosa Arcangeli
      Molecular Pharmacology February 2015, 87 (2) 183-196; DOI: https://doi.org/10.1124/mol.114.094920
  15. Motamedi, Massoud

    1. You have access
      Pharmacological Inhibition and Genetic Knockdown of Exchange Protein Directly Activated by cAMP 1 Reduce Pancreatic Cancer Metastasis In Vivo
      Muayad Almahariq, Celia Chao, Fang C. Mei, Mark R. Hellmich, Igor Patrikeev, Massoud Motamedi and Xiaodong Cheng
      Molecular Pharmacology February 2015, 87 (2) 142-149; DOI: https://doi.org/10.1124/mol.114.095158
  16. Mugridge, Kenneth

    1. You have access
      New Pyrimido-Indole Compound CD-160130 Preferentially Inhibits the KV11.1B Isoform and Produces Antileukemic Effects without Cardiotoxicity
      Luca Gasparoli, Massimo D’Amico, Marika Masselli, Serena Pillozzi, Rachel Caves, Rawan Khuwaileh, Wolfgang Tiedke, Kenneth Mugridge, Alessandro Pratesi, John S. Mitcheson, Giuseppe Basso, Andrea Becchetti and Annarosa Arcangeli
      Molecular Pharmacology February 2015, 87 (2) 183-196; DOI: https://doi.org/10.1124/mol.114.094920
  17. Müller, Rolf

    1. You have access
      The Inverse Agonist DG172 Triggers a PPARβ/δ-Independent Myeloid Lineage Shift and Promotes GM-CSF/IL-4-Induced Dendritic Cell Differentiation
      Sonja Lieber, Frithjof Scheer, Florian Finkernagel, Wolfgang Meissner, Gavin Giehl, Cornelia Brendel, Wibke E. Diederich, Sabine Müller-Brüsselbach and Rolf Müller
      Molecular Pharmacology February 2015, 87 (2) 162-173; DOI: https://doi.org/10.1124/mol.114.094672
  18. Müller-Brüsselbach, Sabine

    1. You have access
      The Inverse Agonist DG172 Triggers a PPARβ/δ-Independent Myeloid Lineage Shift and Promotes GM-CSF/IL-4-Induced Dendritic Cell Differentiation
      Sonja Lieber, Frithjof Scheer, Florian Finkernagel, Wolfgang Meissner, Gavin Giehl, Cornelia Brendel, Wibke E. Diederich, Sabine Müller-Brüsselbach and Rolf Müller
      Molecular Pharmacology February 2015, 87 (2) 162-173; DOI: https://doi.org/10.1124/mol.114.094672

N

  1. Naesens, Lieve

    1. You have access
      An Integrated Biological Approach to Guide the Development of Metal-Chelating Inhibitors of Influenza Virus PA Endonuclease
      Annelies Stevaert, Salvatore Nurra, Nicolino Pala, Mauro Carcelli, Dominga Rogolino, Caitlin Shepard, Robert A. Domaoal, Baek Kim, Mercedes Alfonso-Prieto, Salvatore A. E. Marras, Mario Sechi and Lieve Naesens
      Molecular Pharmacology February 2015, 87 (2) 323-337; DOI: https://doi.org/10.1124/mol.114.095588
  2. Nahta, Rita

    1. You have access
      Insulin-Like Growth Factor-1 Receptor Signaling Increases the Invasive Potential of Human Epidermal Growth Factor Receptor 2–Overexpressing Breast Cancer Cells via Src-Focal Adhesion Kinase and Forkhead Box Protein M1
      Eduardo Sanabria-Figueroa, Siobhan M. Donnelly, Kevin C. Foy, Meghan C. Buss, Robert C. Castellino, Elisavet Paplomata, Latonia Taliaferro-Smith, Pravin T.P. Kaumaya and Rita Nahta
      Molecular Pharmacology February 2015, 87 (2) 150-161; DOI: https://doi.org/10.1124/mol.114.095380
  3. Nishida, Teruo

    1. You have access
      Signaling Mechanism Underlying the Promotion of Keratinocyte Migration by Angiotensin II
      Hiroki Sakai, Kenji Matsuura, Yoshie Tanaka, Takeshi Honda, Teruo Nishida and Makoto Inui
      Molecular Pharmacology February 2015, 87 (2) 277-285; DOI: https://doi.org/10.1124/mol.114.096461
  4. Nuhant, Philippe

    1. You have access
      Antiproliferation Activity of a Small Molecule Repressor of Liver Receptor Homolog 1
      Cesar A. Corzo, Yelenis Mari, Mi Ra Chang, Tanya Khan, Dana Kuruvilla, Philippe Nuhant, Naresh Kumar, Graham M. West, Derek R. Duckett, William R. Roush and Patrick R. Griffin
      Molecular Pharmacology February 2015, 87 (2) 296-304; DOI: https://doi.org/10.1124/mol.114.095554
  5. Nurra, Salvatore

    1. You have access
      An Integrated Biological Approach to Guide the Development of Metal-Chelating Inhibitors of Influenza Virus PA Endonuclease
      Annelies Stevaert, Salvatore Nurra, Nicolino Pala, Mauro Carcelli, Dominga Rogolino, Caitlin Shepard, Robert A. Domaoal, Baek Kim, Mercedes Alfonso-Prieto, Salvatore A. E. Marras, Mario Sechi and Lieve Naesens
      Molecular Pharmacology February 2015, 87 (2) 323-337; DOI: https://doi.org/10.1124/mol.114.095588

O

  1. Ohdo, Shigehiro

    1. You have access
      Modulation of Peroxisome Proliferator-Activated Receptor-α Activity by Bile Acids Causes Circadian Changes in the Intestinal Expression of Octn1/Slc22a4 in Mice
      Erika Wada, Satoru Koyanagi, Naoki Kusunose, Takahiro Akamine, Hiroaki Masui, Hana Hashimoto, Naoya Matsunaga and Shigehiro Ohdo
      Molecular Pharmacology February 2015, 87 (2) 314-322; DOI: https://doi.org/10.1124/mol.114.094979
  2. Oliván-Viguera, Aida

    1. You have access
      A Novel Pan-Negative-Gating Modulator of KCa2/3 Channels, Fluoro-Di-Benzoate, RA-2, Inhibits Endothelium-Derived Hyperpolarization–Type Relaxation in Coronary Artery and Produces Bradycardia In Vivo
      Aida Oliván-Viguera, Marta Sofía Valero, Nicole Coleman, Brandon M. Brown, Celia Laría, María Divina Murillo, José A. Gálvez, María D. Díaz-de-Villegas, Heike Wulff, Ramón Badorrey and Ralf Köhler
      Molecular Pharmacology February 2015, 87 (2) 338-348; DOI: https://doi.org/10.1124/mol.114.095745
  3. Olszewska, Teresa

    1. You have access
      (4-(Bis(4-Fluorophenyl)Methyl)Piperazin-1-yl)(Cyclohexyl)Methanone Hydrochloride (LDK1229): A New Cannabinoid CB1 Receptor Inverse Agonist from the Class of Benzhydryl Piperazine Analogs
      Mariam M. Mahmoud, Teresa Olszewska, Hui Liu, Derek M. Shore, Dow P. Hurst, Patricia H. Reggio, Dai Lu and Debra A. Kendall
      Molecular Pharmacology February 2015, 87 (2) 197-206; DOI: https://doi.org/10.1124/mol.114.095471
  4. Ortiz Zacarías, Natalia V.

    1. You have access
      Sodium Ion Binding Pocket Mutations and Adenosine A2A Receptor Function
      Arnault Massink, Hugo Gutiérrez-de-Terán, Eelke B. Lenselink, Natalia V. Ortiz Zacarías, Lizi Xia, Laura H. Heitman, Vsevolod Katritch, Raymond C. Stevens and Adriaan P. IJzerman
      Molecular Pharmacology February 2015, 87 (2) 305-313; DOI: https://doi.org/10.1124/mol.114.095737

P

  1. Pala, Nicolino

    1. You have access
      An Integrated Biological Approach to Guide the Development of Metal-Chelating Inhibitors of Influenza Virus PA Endonuclease
      Annelies Stevaert, Salvatore Nurra, Nicolino Pala, Mauro Carcelli, Dominga Rogolino, Caitlin Shepard, Robert A. Domaoal, Baek Kim, Mercedes Alfonso-Prieto, Salvatore A. E. Marras, Mario Sechi and Lieve Naesens
      Molecular Pharmacology February 2015, 87 (2) 323-337; DOI: https://doi.org/10.1124/mol.114.095588
  2. Paplomata, Elisavet

    1. You have access
      Insulin-Like Growth Factor-1 Receptor Signaling Increases the Invasive Potential of Human Epidermal Growth Factor Receptor 2–Overexpressing Breast Cancer Cells via Src-Focal Adhesion Kinase and Forkhead Box Protein M1
      Eduardo Sanabria-Figueroa, Siobhan M. Donnelly, Kevin C. Foy, Meghan C. Buss, Robert C. Castellino, Elisavet Paplomata, Latonia Taliaferro-Smith, Pravin T.P. Kaumaya and Rita Nahta
      Molecular Pharmacology February 2015, 87 (2) 150-161; DOI: https://doi.org/10.1124/mol.114.095380
  3. Patrikeev, Igor

    1. You have access
      Pharmacological Inhibition and Genetic Knockdown of Exchange Protein Directly Activated by cAMP 1 Reduce Pancreatic Cancer Metastasis In Vivo
      Muayad Almahariq, Celia Chao, Fang C. Mei, Mark R. Hellmich, Igor Patrikeev, Massoud Motamedi and Xiaodong Cheng
      Molecular Pharmacology February 2015, 87 (2) 142-149; DOI: https://doi.org/10.1124/mol.114.095158
  4. Phipps, Elizabeth A.

    1. You have access
      A Peptide Mimicking a Region in Proliferating Cell Nuclear Antigen Specific to Key Protein Interactions Is Cytotoxic to Breast Cancer
      Shanna J. Smith, Long Gu, Elizabeth A. Phipps, Lacey E. Dobrolecki, Karla S. Mabrey, Pattie Gulley, Kelsey L. Dillehay, Zhongyun Dong, Gregg B. Fields, Yun-Ru Chen, David Ann, Robert J. Hickey and Linda H. Malkas
      Molecular Pharmacology February 2015, 87 (2) 263-276; DOI: https://doi.org/10.1124/mol.114.093211
  5. Pillozzi, Serena

    1. You have access
      New Pyrimido-Indole Compound CD-160130 Preferentially Inhibits the KV11.1B Isoform and Produces Antileukemic Effects without Cardiotoxicity
      Luca Gasparoli, Massimo D’Amico, Marika Masselli, Serena Pillozzi, Rachel Caves, Rawan Khuwaileh, Wolfgang Tiedke, Kenneth Mugridge, Alessandro Pratesi, John S. Mitcheson, Giuseppe Basso, Andrea Becchetti and Annarosa Arcangeli
      Molecular Pharmacology February 2015, 87 (2) 183-196; DOI: https://doi.org/10.1124/mol.114.094920
  6. Pratesi, Alessandro

    1. You have access
      New Pyrimido-Indole Compound CD-160130 Preferentially Inhibits the KV11.1B Isoform and Produces Antileukemic Effects without Cardiotoxicity
      Luca Gasparoli, Massimo D’Amico, Marika Masselli, Serena Pillozzi, Rachel Caves, Rawan Khuwaileh, Wolfgang Tiedke, Kenneth Mugridge, Alessandro Pratesi, John S. Mitcheson, Giuseppe Basso, Andrea Becchetti and Annarosa Arcangeli
      Molecular Pharmacology February 2015, 87 (2) 183-196; DOI: https://doi.org/10.1124/mol.114.094920

Q

  1. Quinn, Bridget A.

    1. You have access
      Reversing Translational Suppression and Induction of Toxicity in Pancreatic Cancer Cells Using a Chemoprevention Gene Therapy Approach
      Siddik Sarkar, Bridget A. Quinn, Xuening Shen, Paul Dent, Swadesh K. Das, Luni Emdad, Devanand Sarkar and Paul B. Fisher
      Molecular Pharmacology February 2015, 87 (2) 286-295; DOI: https://doi.org/10.1124/mol.114.094375

R

  1. Reggio, Patricia H.

    1. You have access
      (4-(Bis(4-Fluorophenyl)Methyl)Piperazin-1-yl)(Cyclohexyl)Methanone Hydrochloride (LDK1229): A New Cannabinoid CB1 Receptor Inverse Agonist from the Class of Benzhydryl Piperazine Analogs
      Mariam M. Mahmoud, Teresa Olszewska, Hui Liu, Derek M. Shore, Dow P. Hurst, Patricia H. Reggio, Dai Lu and Debra A. Kendall
      Molecular Pharmacology February 2015, 87 (2) 197-206; DOI: https://doi.org/10.1124/mol.114.095471
  2. Rogolino, Dominga

    1. You have access
      An Integrated Biological Approach to Guide the Development of Metal-Chelating Inhibitors of Influenza Virus PA Endonuclease
      Annelies Stevaert, Salvatore Nurra, Nicolino Pala, Mauro Carcelli, Dominga Rogolino, Caitlin Shepard, Robert A. Domaoal, Baek Kim, Mercedes Alfonso-Prieto, Salvatore A. E. Marras, Mario Sechi and Lieve Naesens
      Molecular Pharmacology February 2015, 87 (2) 323-337; DOI: https://doi.org/10.1124/mol.114.095588
  3. Roobrouck, A.

    1. You have access
      Potent and Efficacious Inhibition of CXCR2 Signaling by Biparatopic Nanobodies Combining Two Distinct Modes of Action
      M. E. Bradley, B. Dombrecht, J. Manini, J. Willis, D. Vlerick, S. De Taeye, K. Van den Heede, A. Roobrouck, E. Grot, T. C. Kent, T. Laeremans, S. Steffensen, G. Van Heeke, Z. Brown, S. J. Charlton and K. D. Cromie
      Molecular Pharmacology February 2015, 87 (2) 251-262; DOI: https://doi.org/10.1124/mol.114.094821
  4. Roush, William R.

    1. You have access
      Antiproliferation Activity of a Small Molecule Repressor of Liver Receptor Homolog 1
      Cesar A. Corzo, Yelenis Mari, Mi Ra Chang, Tanya Khan, Dana Kuruvilla, Philippe Nuhant, Naresh Kumar, Graham M. West, Derek R. Duckett, William R. Roush and Patrick R. Griffin
      Molecular Pharmacology February 2015, 87 (2) 296-304; DOI: https://doi.org/10.1124/mol.114.095554

S

  1. Sakai, Hiroki

    1. You have access
      Signaling Mechanism Underlying the Promotion of Keratinocyte Migration by Angiotensin II
      Hiroki Sakai, Kenji Matsuura, Yoshie Tanaka, Takeshi Honda, Teruo Nishida and Makoto Inui
      Molecular Pharmacology February 2015, 87 (2) 277-285; DOI: https://doi.org/10.1124/mol.114.096461
  2. Sanabria-Figueroa, Eduardo

    1. You have access
      Insulin-Like Growth Factor-1 Receptor Signaling Increases the Invasive Potential of Human Epidermal Growth Factor Receptor 2–Overexpressing Breast Cancer Cells via Src-Focal Adhesion Kinase and Forkhead Box Protein M1
      Eduardo Sanabria-Figueroa, Siobhan M. Donnelly, Kevin C. Foy, Meghan C. Buss, Robert C. Castellino, Elisavet Paplomata, Latonia Taliaferro-Smith, Pravin T.P. Kaumaya and Rita Nahta
      Molecular Pharmacology February 2015, 87 (2) 150-161; DOI: https://doi.org/10.1124/mol.114.095380
  3. Sarkar, Devanand

    1. You have access
      Reversing Translational Suppression and Induction of Toxicity in Pancreatic Cancer Cells Using a Chemoprevention Gene Therapy Approach
      Siddik Sarkar, Bridget A. Quinn, Xuening Shen, Paul Dent, Swadesh K. Das, Luni Emdad, Devanand Sarkar and Paul B. Fisher
      Molecular Pharmacology February 2015, 87 (2) 286-295; DOI: https://doi.org/10.1124/mol.114.094375
  4. Sarkar, Siddik

    1. You have access
      Reversing Translational Suppression and Induction of Toxicity in Pancreatic Cancer Cells Using a Chemoprevention Gene Therapy Approach
      Siddik Sarkar, Bridget A. Quinn, Xuening Shen, Paul Dent, Swadesh K. Das, Luni Emdad, Devanand Sarkar and Paul B. Fisher
      Molecular Pharmacology February 2015, 87 (2) 286-295; DOI: https://doi.org/10.1124/mol.114.094375
  5. Scheer, Frithjof

    1. You have access
      The Inverse Agonist DG172 Triggers a PPARβ/δ-Independent Myeloid Lineage Shift and Promotes GM-CSF/IL-4-Induced Dendritic Cell Differentiation
      Sonja Lieber, Frithjof Scheer, Florian Finkernagel, Wolfgang Meissner, Gavin Giehl, Cornelia Brendel, Wibke E. Diederich, Sabine Müller-Brüsselbach and Rolf Müller
      Molecular Pharmacology February 2015, 87 (2) 162-173; DOI: https://doi.org/10.1124/mol.114.094672
  6. Sechi, Mario

    1. You have access
      An Integrated Biological Approach to Guide the Development of Metal-Chelating Inhibitors of Influenza Virus PA Endonuclease
      Annelies Stevaert, Salvatore Nurra, Nicolino Pala, Mauro Carcelli, Dominga Rogolino, Caitlin Shepard, Robert A. Domaoal, Baek Kim, Mercedes Alfonso-Prieto, Salvatore A. E. Marras, Mario Sechi and Lieve Naesens
      Molecular Pharmacology February 2015, 87 (2) 323-337; DOI: https://doi.org/10.1124/mol.114.095588
  7. Shen, Xuening

    1. You have access
      Reversing Translational Suppression and Induction of Toxicity in Pancreatic Cancer Cells Using a Chemoprevention Gene Therapy Approach
      Siddik Sarkar, Bridget A. Quinn, Xuening Shen, Paul Dent, Swadesh K. Das, Luni Emdad, Devanand Sarkar and Paul B. Fisher
      Molecular Pharmacology February 2015, 87 (2) 286-295; DOI: https://doi.org/10.1124/mol.114.094375
  8. Shepard, Caitlin

    1. You have access
      An Integrated Biological Approach to Guide the Development of Metal-Chelating Inhibitors of Influenza Virus PA Endonuclease
      Annelies Stevaert, Salvatore Nurra, Nicolino Pala, Mauro Carcelli, Dominga Rogolino, Caitlin Shepard, Robert A. Domaoal, Baek Kim, Mercedes Alfonso-Prieto, Salvatore A. E. Marras, Mario Sechi and Lieve Naesens
      Molecular Pharmacology February 2015, 87 (2) 323-337; DOI: https://doi.org/10.1124/mol.114.095588
  9. Shore, Derek M.

    1. You have access
      (4-(Bis(4-Fluorophenyl)Methyl)Piperazin-1-yl)(Cyclohexyl)Methanone Hydrochloride (LDK1229): A New Cannabinoid CB1 Receptor Inverse Agonist from the Class of Benzhydryl Piperazine Analogs
      Mariam M. Mahmoud, Teresa Olszewska, Hui Liu, Derek M. Shore, Dow P. Hurst, Patricia H. Reggio, Dai Lu and Debra A. Kendall
      Molecular Pharmacology February 2015, 87 (2) 197-206; DOI: https://doi.org/10.1124/mol.114.095471
  10. Slesinger, Paul A.

    1. You have access
      Novel Mechanism of Voltage-Gated N-type (Cav2.2) Calcium Channel Inhibition Revealed through α-Conotoxin Vc1.1 Activation of the GABAB Receptor
      Thuan G. Huynh, Hartmut Cuny, Paul A. Slesinger and David J. Adams
      Molecular Pharmacology February 2015, 87 (2) 240-250; DOI: https://doi.org/10.1124/mol.114.096156
  11. Smith, Shanna J.

    1. You have access
      A Peptide Mimicking a Region in Proliferating Cell Nuclear Antigen Specific to Key Protein Interactions Is Cytotoxic to Breast Cancer
      Shanna J. Smith, Long Gu, Elizabeth A. Phipps, Lacey E. Dobrolecki, Karla S. Mabrey, Pattie Gulley, Kelsey L. Dillehay, Zhongyun Dong, Gregg B. Fields, Yun-Ru Chen, David Ann, Robert J. Hickey and Linda H. Malkas
      Molecular Pharmacology February 2015, 87 (2) 263-276; DOI: https://doi.org/10.1124/mol.114.093211
  12. Steffensen, S.

    1. You have access
      Potent and Efficacious Inhibition of CXCR2 Signaling by Biparatopic Nanobodies Combining Two Distinct Modes of Action
      M. E. Bradley, B. Dombrecht, J. Manini, J. Willis, D. Vlerick, S. De Taeye, K. Van den Heede, A. Roobrouck, E. Grot, T. C. Kent, T. Laeremans, S. Steffensen, G. Van Heeke, Z. Brown, S. J. Charlton and K. D. Cromie
      Molecular Pharmacology February 2015, 87 (2) 251-262; DOI: https://doi.org/10.1124/mol.114.094821
  13. Stevaert, Annelies

    1. You have access
      An Integrated Biological Approach to Guide the Development of Metal-Chelating Inhibitors of Influenza Virus PA Endonuclease
      Annelies Stevaert, Salvatore Nurra, Nicolino Pala, Mauro Carcelli, Dominga Rogolino, Caitlin Shepard, Robert A. Domaoal, Baek Kim, Mercedes Alfonso-Prieto, Salvatore A. E. Marras, Mario Sechi and Lieve Naesens
      Molecular Pharmacology February 2015, 87 (2) 323-337; DOI: https://doi.org/10.1124/mol.114.095588
  14. Stevens, Raymond C.

    1. You have access
      Sodium Ion Binding Pocket Mutations and Adenosine A2A Receptor Function
      Arnault Massink, Hugo Gutiérrez-de-Terán, Eelke B. Lenselink, Natalia V. Ortiz Zacarías, Lizi Xia, Laura H. Heitman, Vsevolod Katritch, Raymond C. Stevens and Adriaan P. IJzerman
      Molecular Pharmacology February 2015, 87 (2) 305-313; DOI: https://doi.org/10.1124/mol.114.095737

T

  1. Taliaferro-Smith, Latonia

    1. You have access
      Insulin-Like Growth Factor-1 Receptor Signaling Increases the Invasive Potential of Human Epidermal Growth Factor Receptor 2–Overexpressing Breast Cancer Cells via Src-Focal Adhesion Kinase and Forkhead Box Protein M1
      Eduardo Sanabria-Figueroa, Siobhan M. Donnelly, Kevin C. Foy, Meghan C. Buss, Robert C. Castellino, Elisavet Paplomata, Latonia Taliaferro-Smith, Pravin T.P. Kaumaya and Rita Nahta
      Molecular Pharmacology February 2015, 87 (2) 150-161; DOI: https://doi.org/10.1124/mol.114.095380
  2. Tanaka, Yoshie

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      Signaling Mechanism Underlying the Promotion of Keratinocyte Migration by Angiotensin II
      Hiroki Sakai, Kenji Matsuura, Yoshie Tanaka, Takeshi Honda, Teruo Nishida and Makoto Inui
      Molecular Pharmacology February 2015, 87 (2) 277-285; DOI: https://doi.org/10.1124/mol.114.096461
  3. Tiedke, Wolfgang

    1. You have access
      New Pyrimido-Indole Compound CD-160130 Preferentially Inhibits the KV11.1B Isoform and Produces Antileukemic Effects without Cardiotoxicity
      Luca Gasparoli, Massimo D’Amico, Marika Masselli, Serena Pillozzi, Rachel Caves, Rawan Khuwaileh, Wolfgang Tiedke, Kenneth Mugridge, Alessandro Pratesi, John S. Mitcheson, Giuseppe Basso, Andrea Becchetti and Annarosa Arcangeli
      Molecular Pharmacology February 2015, 87 (2) 183-196; DOI: https://doi.org/10.1124/mol.114.094920
  4. Tobin, Andrew B.

    1. You have access
      Engineered Hyperphosphorylation of the β2-Adrenoceptor Prolongs Arrestin-3 Binding and Induces Arrestin Internalization
      Diana Zindel, Adrian J. Butcher, Suleiman Al-Sabah, Peter Lanzerstorfer, Julian Weghuber, Andrew B. Tobin, Moritz Bünemann and Cornelius Krasel
      Molecular Pharmacology February 2015, 87 (2) 349-362; DOI: https://doi.org/10.1124/mol.114.095422
  5. Tsai, Keng-Chang

    1. You have access
      Phage Display–Mediated Discovery of Novel Tyrosinase-Targeting Tetrapeptide Inhibitors Reveals the Significance of N-Terminal Preference of Cysteine Residues and Their Functional Sulfur Atom
      Yu-Ching Lee, Nai-Wan Hsiao, Tien-Sheng Tseng, Wang-Chuan Chen, Hui-Hsiung Lin, Sy-Jye Leu, Ei-Wen Yang and Keng-Chang Tsai
      Molecular Pharmacology February 2015, 87 (2) 218-230; DOI: https://doi.org/10.1124/mol.114.094185
  6. Tseng, Tien-Sheng

    1. You have access
      Phage Display–Mediated Discovery of Novel Tyrosinase-Targeting Tetrapeptide Inhibitors Reveals the Significance of N-Terminal Preference of Cysteine Residues and Their Functional Sulfur Atom
      Yu-Ching Lee, Nai-Wan Hsiao, Tien-Sheng Tseng, Wang-Chuan Chen, Hui-Hsiung Lin, Sy-Jye Leu, Ei-Wen Yang and Keng-Chang Tsai
      Molecular Pharmacology February 2015, 87 (2) 218-230; DOI: https://doi.org/10.1124/mol.114.094185

V

  1. Valero, Marta Sofía

    1. You have access
      A Novel Pan-Negative-Gating Modulator of KCa2/3 Channels, Fluoro-Di-Benzoate, RA-2, Inhibits Endothelium-Derived Hyperpolarization–Type Relaxation in Coronary Artery and Produces Bradycardia In Vivo
      Aida Oliván-Viguera, Marta Sofía Valero, Nicole Coleman, Brandon M. Brown, Celia Laría, María Divina Murillo, José A. Gálvez, María D. Díaz-de-Villegas, Heike Wulff, Ramón Badorrey and Ralf Köhler
      Molecular Pharmacology February 2015, 87 (2) 338-348; DOI: https://doi.org/10.1124/mol.114.095745
  2. Van den Heede, K.

    1. You have access
      Potent and Efficacious Inhibition of CXCR2 Signaling by Biparatopic Nanobodies Combining Two Distinct Modes of Action
      M. E. Bradley, B. Dombrecht, J. Manini, J. Willis, D. Vlerick, S. De Taeye, K. Van den Heede, A. Roobrouck, E. Grot, T. C. Kent, T. Laeremans, S. Steffensen, G. Van Heeke, Z. Brown, S. J. Charlton and K. D. Cromie
      Molecular Pharmacology February 2015, 87 (2) 251-262; DOI: https://doi.org/10.1124/mol.114.094821
  3. Van Heeke, G.

    1. You have access
      Potent and Efficacious Inhibition of CXCR2 Signaling by Biparatopic Nanobodies Combining Two Distinct Modes of Action
      M. E. Bradley, B. Dombrecht, J. Manini, J. Willis, D. Vlerick, S. De Taeye, K. Van den Heede, A. Roobrouck, E. Grot, T. C. Kent, T. Laeremans, S. Steffensen, G. Van Heeke, Z. Brown, S. J. Charlton and K. D. Cromie
      Molecular Pharmacology February 2015, 87 (2) 251-262; DOI: https://doi.org/10.1124/mol.114.094821
  4. Vlerick, D.

    1. You have access
      Potent and Efficacious Inhibition of CXCR2 Signaling by Biparatopic Nanobodies Combining Two Distinct Modes of Action
      M. E. Bradley, B. Dombrecht, J. Manini, J. Willis, D. Vlerick, S. De Taeye, K. Van den Heede, A. Roobrouck, E. Grot, T. C. Kent, T. Laeremans, S. Steffensen, G. Van Heeke, Z. Brown, S. J. Charlton and K. D. Cromie
      Molecular Pharmacology February 2015, 87 (2) 251-262; DOI: https://doi.org/10.1124/mol.114.094821

W

  1. Wada, Erika

    1. You have access
      Modulation of Peroxisome Proliferator-Activated Receptor-α Activity by Bile Acids Causes Circadian Changes in the Intestinal Expression of Octn1/Slc22a4 in Mice
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      Molecular Pharmacology February 2015, 87 (2) 314-322; DOI: https://doi.org/10.1124/mol.114.094979
  2. Weghuber, Julian

    1. You have access
      Engineered Hyperphosphorylation of the β2-Adrenoceptor Prolongs Arrestin-3 Binding and Induces Arrestin Internalization
      Diana Zindel, Adrian J. Butcher, Suleiman Al-Sabah, Peter Lanzerstorfer, Julian Weghuber, Andrew B. Tobin, Moritz Bünemann and Cornelius Krasel
      Molecular Pharmacology February 2015, 87 (2) 349-362; DOI: https://doi.org/10.1124/mol.114.095422
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      Antiproliferation Activity of a Small Molecule Repressor of Liver Receptor Homolog 1
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      Molecular Pharmacology February 2015, 87 (2) 296-304; DOI: https://doi.org/10.1124/mol.114.095554
  4. Willis, J.

    1. You have access
      Potent and Efficacious Inhibition of CXCR2 Signaling by Biparatopic Nanobodies Combining Two Distinct Modes of Action
      M. E. Bradley, B. Dombrecht, J. Manini, J. Willis, D. Vlerick, S. De Taeye, K. Van den Heede, A. Roobrouck, E. Grot, T. C. Kent, T. Laeremans, S. Steffensen, G. Van Heeke, Z. Brown, S. J. Charlton and K. D. Cromie
      Molecular Pharmacology February 2015, 87 (2) 251-262; DOI: https://doi.org/10.1124/mol.114.094821
  5. Wulff, Heike

    1. You have access
      A Novel Pan-Negative-Gating Modulator of KCa2/3 Channels, Fluoro-Di-Benzoate, RA-2, Inhibits Endothelium-Derived Hyperpolarization–Type Relaxation in Coronary Artery and Produces Bradycardia In Vivo
      Aida Oliván-Viguera, Marta Sofía Valero, Nicole Coleman, Brandon M. Brown, Celia Laría, María Divina Murillo, José A. Gálvez, María D. Díaz-de-Villegas, Heike Wulff, Ramón Badorrey and Ralf Köhler
      Molecular Pharmacology February 2015, 87 (2) 338-348; DOI: https://doi.org/10.1124/mol.114.095745

X

  1. Xia, Lizi

    1. You have access
      Sodium Ion Binding Pocket Mutations and Adenosine A2A Receptor Function
      Arnault Massink, Hugo Gutiérrez-de-Terán, Eelke B. Lenselink, Natalia V. Ortiz Zacarías, Lizi Xia, Laura H. Heitman, Vsevolod Katritch, Raymond C. Stevens and Adriaan P. IJzerman
      Molecular Pharmacology February 2015, 87 (2) 305-313; DOI: https://doi.org/10.1124/mol.114.095737
  2. Xu, Kaiping

    1. You have access
      Reporting Sodium Channel Activity Using Calcium Flux: Pharmacological Promiscuity of Cardiac Nav1.5
      Hongkang Zhang, Beiyan Zou, Fang Du, Kaiping Xu and Min Li
      Molecular Pharmacology February 2015, 87 (2) 207-217; DOI: https://doi.org/10.1124/mol.114.094789

Y

  1. Yang, Ei-Wen

    1. You have access
      Phage Display–Mediated Discovery of Novel Tyrosinase-Targeting Tetrapeptide Inhibitors Reveals the Significance of N-Terminal Preference of Cysteine Residues and Their Functional Sulfur Atom
      Yu-Ching Lee, Nai-Wan Hsiao, Tien-Sheng Tseng, Wang-Chuan Chen, Hui-Hsiung Lin, Sy-Jye Leu, Ei-Wen Yang and Keng-Chang Tsai
      Molecular Pharmacology February 2015, 87 (2) 218-230; DOI: https://doi.org/10.1124/mol.114.094185

Z

  1. Zhang, Hongkang

    1. You have access
      Reporting Sodium Channel Activity Using Calcium Flux: Pharmacological Promiscuity of Cardiac Nav1.5
      Hongkang Zhang, Beiyan Zou, Fang Du, Kaiping Xu and Min Li
      Molecular Pharmacology February 2015, 87 (2) 207-217; DOI: https://doi.org/10.1124/mol.114.094789
  2. Zindel, Diana

    1. You have access
      Engineered Hyperphosphorylation of the β2-Adrenoceptor Prolongs Arrestin-3 Binding and Induces Arrestin Internalization
      Diana Zindel, Adrian J. Butcher, Suleiman Al-Sabah, Peter Lanzerstorfer, Julian Weghuber, Andrew B. Tobin, Moritz Bünemann and Cornelius Krasel
      Molecular Pharmacology February 2015, 87 (2) 349-362; DOI: https://doi.org/10.1124/mol.114.095422
  3. Zou, Beiyan

    1. You have access
      Reporting Sodium Channel Activity Using Calcium Flux: Pharmacological Promiscuity of Cardiac Nav1.5
      Hongkang Zhang, Beiyan Zou, Fang Du, Kaiping Xu and Min Li
      Molecular Pharmacology February 2015, 87 (2) 207-217; DOI: https://doi.org/10.1124/mol.114.094789
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Molecular Pharmacology: 87 (2)
Molecular Pharmacology
Vol. 87, Issue 2
1 Feb 2015
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  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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