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Index by author

February 01, 2015; Volume 87,Issue 2

A

  1. Abkhezr, Mousa

    1. RETRACTION: STAT3 Regulates Steady-State Expression of Synaptopodin in Cultured Mouse Podocytes
      Mousa Abkhezr and Stuart E. Dryer
      Molecular Pharmacology February 2015, 87 (2) 231-239; DOI: https://doi.org/10.1124/mol.114.094508

  2. Adams, David J.

    1. Novel Mechanism of Voltage-Gated N-type (Cav2.2) Calcium Channel Inhibition Revealed through α-Conotoxin Vc1.1 Activation of the GABAB Receptor
      Thuan G. Huynh, Hartmut Cuny, Paul A. Slesinger and David J. Adams
      Molecular Pharmacology February 2015, 87 (2) 240-250; DOI: https://doi.org/10.1124/mol.114.096156

  3. Akamine, Takahiro

    1. Modulation of Peroxisome Proliferator-Activated Receptor-α Activity by Bile Acids Causes Circadian Changes in the Intestinal Expression of Octn1/Slc22a4 in Mice
      Erika Wada, Satoru Koyanagi, Naoki Kusunose, Takahiro Akamine, Hiroaki Masui, Hana Hashimoto, Naoya Matsunaga and Shigehiro Ohdo
      Molecular Pharmacology February 2015, 87 (2) 314-322; DOI: https://doi.org/10.1124/mol.114.094979

  4. Al-Sabah, Suleiman

    1. Engineered Hyperphosphorylation of the β2-Adrenoceptor Prolongs Arrestin-3 Binding and Induces Arrestin Internalization
      Diana Zindel, Adrian J. Butcher, Suleiman Al-Sabah, Peter Lanzerstorfer, Julian Weghuber, Andrew B. Tobin, Moritz Bünemann and Cornelius Krasel
      Molecular Pharmacology February 2015, 87 (2) 349-362; DOI: https://doi.org/10.1124/mol.114.095422

  5. Alfonso-Prieto, Mercedes

    1. An Integrated Biological Approach to Guide the Development of Metal-Chelating Inhibitors of Influenza Virus PA Endonuclease
      Annelies Stevaert, Salvatore Nurra, Nicolino Pala, Mauro Carcelli, Dominga Rogolino, Caitlin Shepard, Robert A. Domaoal, Baek Kim, Mercedes Alfonso-Prieto, Salvatore A. E. Marras, Mario Sechi and Lieve Naesens
      Molecular Pharmacology February 2015, 87 (2) 323-337; DOI: https://doi.org/10.1124/mol.114.095588

  6. Almahariq, Muayad

    1. Pharmacological Inhibition and Genetic Knockdown of Exchange Protein Directly Activated by cAMP 1 Reduce Pancreatic Cancer Metastasis In Vivo
      Muayad Almahariq, Celia Chao, Fang C. Mei, Mark R. Hellmich, Igor Patrikeev, Massoud Motamedi and Xiaodong Cheng
      Molecular Pharmacology February 2015, 87 (2) 142-149; DOI: https://doi.org/10.1124/mol.114.095158

  7. Ann, David

    1. A Peptide Mimicking a Region in Proliferating Cell Nuclear Antigen Specific to Key Protein Interactions Is Cytotoxic to Breast Cancer
      Shanna J. Smith, Long Gu, Elizabeth A. Phipps, Lacey E. Dobrolecki, Karla S. Mabrey, Pattie Gulley, Kelsey L. Dillehay, Zhongyun Dong, Gregg B. Fields, Yun-Ru Chen, David Ann, Robert J. Hickey and Linda H. Malkas
      Molecular Pharmacology February 2015, 87 (2) 263-276; DOI: https://doi.org/10.1124/mol.114.093211

  8. Arcangeli, Annarosa

    1. New Pyrimido-Indole Compound CD-160130 Preferentially Inhibits the KV11.1B Isoform and Produces Antileukemic Effects without Cardiotoxicity
      Luca Gasparoli, Massimo D’Amico, Marika Masselli, Serena Pillozzi, Rachel Caves, Rawan Khuwaileh, Wolfgang Tiedke, Kenneth Mugridge, Alessandro Pratesi, John S. Mitcheson, Giuseppe Basso, Andrea Becchetti and Annarosa Arcangeli
      Molecular Pharmacology February 2015, 87 (2) 183-196; DOI: https://doi.org/10.1124/mol.114.094920

B

  1. Badorrey, Ramón

    1. A Novel Pan-Negative-Gating Modulator of KCa2/3 Channels, Fluoro-Di-Benzoate, RA-2, Inhibits Endothelium-Derived Hyperpolarization–Type Relaxation in Coronary Artery and Produces Bradycardia In Vivo
      Aida Oliván-Viguera, Marta Sofía Valero, Nicole Coleman, Brandon M. Brown, Celia Laría, María Divina Murillo, José A. Gálvez, María D. Díaz-de-Villegas, Heike Wulff, Ramón Badorrey and Ralf Köhler
      Molecular Pharmacology February 2015, 87 (2) 338-348; DOI: https://doi.org/10.1124/mol.114.095745

  2. Bai, Yongheng

    1. An Overview of Hedgehog Signaling in Fibrosis
      Liping Hu, Xiangyang Lin, Hong Lu, Bicheng Chen and Yongheng Bai
      Molecular Pharmacology February 2015, 87 (2) 174-182; DOI: https://doi.org/10.1124/mol.114.095141

  3. Basso, Giuseppe

    1. New Pyrimido-Indole Compound CD-160130 Preferentially Inhibits the KV11.1B Isoform and Produces Antileukemic Effects without Cardiotoxicity
      Luca Gasparoli, Massimo D’Amico, Marika Masselli, Serena Pillozzi, Rachel Caves, Rawan Khuwaileh, Wolfgang Tiedke, Kenneth Mugridge, Alessandro Pratesi, John S. Mitcheson, Giuseppe Basso, Andrea Becchetti and Annarosa Arcangeli
      Molecular Pharmacology February 2015, 87 (2) 183-196; DOI: https://doi.org/10.1124/mol.114.094920

  4. Becchetti, Andrea

    1. New Pyrimido-Indole Compound CD-160130 Preferentially Inhibits the KV11.1B Isoform and Produces Antileukemic Effects without Cardiotoxicity
      Luca Gasparoli, Massimo D’Amico, Marika Masselli, Serena Pillozzi, Rachel Caves, Rawan Khuwaileh, Wolfgang Tiedke, Kenneth Mugridge, Alessandro Pratesi, John S. Mitcheson, Giuseppe Basso, Andrea Becchetti and Annarosa Arcangeli
      Molecular Pharmacology February 2015, 87 (2) 183-196; DOI: https://doi.org/10.1124/mol.114.094920

  5. Bradley, M. E.

    1. Potent and Efficacious Inhibition of CXCR2 Signaling by Biparatopic Nanobodies Combining Two Distinct Modes of Action
      M. E. Bradley, B. Dombrecht, J. Manini, J. Willis, D. Vlerick, S. De Taeye, K. Van den Heede, A. Roobrouck, E. Grot, T. C. Kent, T. Laeremans, S. Steffensen, G. Van Heeke, Z. Brown, S. J. Charlton and K. D. Cromie
      Molecular Pharmacology February 2015, 87 (2) 251-262; DOI: https://doi.org/10.1124/mol.114.094821

  6. Brendel, Cornelia

    1. The Inverse Agonist DG172 Triggers a PPARβ/δ-Independent Myeloid Lineage Shift and Promotes GM-CSF/IL-4-Induced Dendritic Cell Differentiation
      Sonja Lieber, Frithjof Scheer, Florian Finkernagel, Wolfgang Meissner, Gavin Giehl, Cornelia Brendel, Wibke E. Diederich, Sabine Müller-Brüsselbach and Rolf Müller
      Molecular Pharmacology February 2015, 87 (2) 162-173; DOI: https://doi.org/10.1124/mol.114.094672

  7. Brown, Brandon M.

    1. A Novel Pan-Negative-Gating Modulator of KCa2/3 Channels, Fluoro-Di-Benzoate, RA-2, Inhibits Endothelium-Derived Hyperpolarization–Type Relaxation in Coronary Artery and Produces Bradycardia In Vivo
      Aida Oliván-Viguera, Marta Sofía Valero, Nicole Coleman, Brandon M. Brown, Celia Laría, María Divina Murillo, José A. Gálvez, María D. Díaz-de-Villegas, Heike Wulff, Ramón Badorrey and Ralf Köhler
      Molecular Pharmacology February 2015, 87 (2) 338-348; DOI: https://doi.org/10.1124/mol.114.095745

  8. Brown, Z.

    1. Potent and Efficacious Inhibition of CXCR2 Signaling by Biparatopic Nanobodies Combining Two Distinct Modes of Action
      M. E. Bradley, B. Dombrecht, J. Manini, J. Willis, D. Vlerick, S. De Taeye, K. Van den Heede, A. Roobrouck, E. Grot, T. C. Kent, T. Laeremans, S. Steffensen, G. Van Heeke, Z. Brown, S. J. Charlton and K. D. Cromie
      Molecular Pharmacology February 2015, 87 (2) 251-262; DOI: https://doi.org/10.1124/mol.114.094821

  9. Bünemann, Moritz

    1. Engineered Hyperphosphorylation of the β2-Adrenoceptor Prolongs Arrestin-3 Binding and Induces Arrestin Internalization
      Diana Zindel, Adrian J. Butcher, Suleiman Al-Sabah, Peter Lanzerstorfer, Julian Weghuber, Andrew B. Tobin, Moritz Bünemann and Cornelius Krasel
      Molecular Pharmacology February 2015, 87 (2) 349-362; DOI: https://doi.org/10.1124/mol.114.095422

  10. Buss, Meghan C.

    1. Insulin-Like Growth Factor-1 Receptor Signaling Increases the Invasive Potential of Human Epidermal Growth Factor Receptor 2–Overexpressing Breast Cancer Cells via Src-Focal Adhesion Kinase and Forkhead Box Protein M1
      Eduardo Sanabria-Figueroa, Siobhan M. Donnelly, Kevin C. Foy, Meghan C. Buss, Robert C. Castellino, Elisavet Paplomata, Latonia Taliaferro-Smith, Pravin T.P. Kaumaya and Rita Nahta
      Molecular Pharmacology February 2015, 87 (2) 150-161; DOI: https://doi.org/10.1124/mol.114.095380

  11. Butcher, Adrian J.

    1. Engineered Hyperphosphorylation of the β2-Adrenoceptor Prolongs Arrestin-3 Binding and Induces Arrestin Internalization
      Diana Zindel, Adrian J. Butcher, Suleiman Al-Sabah, Peter Lanzerstorfer, Julian Weghuber, Andrew B. Tobin, Moritz Bünemann and Cornelius Krasel
      Molecular Pharmacology February 2015, 87 (2) 349-362; DOI: https://doi.org/10.1124/mol.114.095422

C

  1. Carcelli, Mauro

    1. An Integrated Biological Approach to Guide the Development of Metal-Chelating Inhibitors of Influenza Virus PA Endonuclease
      Annelies Stevaert, Salvatore Nurra, Nicolino Pala, Mauro Carcelli, Dominga Rogolino, Caitlin Shepard, Robert A. Domaoal, Baek Kim, Mercedes Alfonso-Prieto, Salvatore A. E. Marras, Mario Sechi and Lieve Naesens
      Molecular Pharmacology February 2015, 87 (2) 323-337; DOI: https://doi.org/10.1124/mol.114.095588

  2. Castellino, Robert C.

    1. Insulin-Like Growth Factor-1 Receptor Signaling Increases the Invasive Potential of Human Epidermal Growth Factor Receptor 2–Overexpressing Breast Cancer Cells via Src-Focal Adhesion Kinase and Forkhead Box Protein M1
      Eduardo Sanabria-Figueroa, Siobhan M. Donnelly, Kevin C. Foy, Meghan C. Buss, Robert C. Castellino, Elisavet Paplomata, Latonia Taliaferro-Smith, Pravin T.P. Kaumaya and Rita Nahta
      Molecular Pharmacology February 2015, 87 (2) 150-161; DOI: https://doi.org/10.1124/mol.114.095380

  3. Caves, Rachel

    1. New Pyrimido-Indole Compound CD-160130 Preferentially Inhibits the KV11.1B Isoform and Produces Antileukemic Effects without Cardiotoxicity
      Luca Gasparoli, Massimo D’Amico, Marika Masselli, Serena Pillozzi, Rachel Caves, Rawan Khuwaileh, Wolfgang Tiedke, Kenneth Mugridge, Alessandro Pratesi, John S. Mitcheson, Giuseppe Basso, Andrea Becchetti and Annarosa Arcangeli
      Molecular Pharmacology February 2015, 87 (2) 183-196; DOI: https://doi.org/10.1124/mol.114.094920

  4. Chang, Mi Ra

    1. Antiproliferation Activity of a Small Molecule Repressor of Liver Receptor Homolog 1
      Cesar A. Corzo, Yelenis Mari, Mi Ra Chang, Tanya Khan, Dana Kuruvilla, Philippe Nuhant, Naresh Kumar, Graham M. West, Derek R. Duckett, William R. Roush and Patrick R. Griffin
      Molecular Pharmacology February 2015, 87 (2) 296-304; DOI: https://doi.org/10.1124/mol.114.095554

  5. Chao, Celia

    1. Pharmacological Inhibition and Genetic Knockdown of Exchange Protein Directly Activated by cAMP 1 Reduce Pancreatic Cancer Metastasis In Vivo
      Muayad Almahariq, Celia Chao, Fang C. Mei, Mark R. Hellmich, Igor Patrikeev, Massoud Motamedi and Xiaodong Cheng
      Molecular Pharmacology February 2015, 87 (2) 142-149; DOI: https://doi.org/10.1124/mol.114.095158

  6. Charlton, S. J.

    1. Potent and Efficacious Inhibition of CXCR2 Signaling by Biparatopic Nanobodies Combining Two Distinct Modes of Action
      M. E. Bradley, B. Dombrecht, J. Manini, J. Willis, D. Vlerick, S. De Taeye, K. Van den Heede, A. Roobrouck, E. Grot, T. C. Kent, T. Laeremans, S. Steffensen, G. Van Heeke, Z. Brown, S. J. Charlton and K. D. Cromie
      Molecular Pharmacology February 2015, 87 (2) 251-262; DOI: https://doi.org/10.1124/mol.114.094821

  7. Chen, Bicheng

    1. An Overview of Hedgehog Signaling in Fibrosis
      Liping Hu, Xiangyang Lin, Hong Lu, Bicheng Chen and Yongheng Bai
      Molecular Pharmacology February 2015, 87 (2) 174-182; DOI: https://doi.org/10.1124/mol.114.095141

  8. Chen, Wang-Chuan

    1. Phage Display–Mediated Discovery of Novel Tyrosinase-Targeting Tetrapeptide Inhibitors Reveals the Significance of N-Terminal Preference of Cysteine Residues and Their Functional Sulfur Atom
      Yu-Ching Lee, Nai-Wan Hsiao, Tien-Sheng Tseng, Wang-Chuan Chen, Hui-Hsiung Lin, Sy-Jye Leu, Ei-Wen Yang and Keng-Chang Tsai
      Molecular Pharmacology February 2015, 87 (2) 218-230; DOI: https://doi.org/10.1124/mol.114.094185

  9. Chen, Yun-Ru

    1. A Peptide Mimicking a Region in Proliferating Cell Nuclear Antigen Specific to Key Protein Interactions Is Cytotoxic to Breast Cancer
      Shanna J. Smith, Long Gu, Elizabeth A. Phipps, Lacey E. Dobrolecki, Karla S. Mabrey, Pattie Gulley, Kelsey L. Dillehay, Zhongyun Dong, Gregg B. Fields, Yun-Ru Chen, David Ann, Robert J. Hickey and Linda H. Malkas
      Molecular Pharmacology February 2015, 87 (2) 263-276; DOI: https://doi.org/10.1124/mol.114.093211

  10. Cheng, Xiaodong

    1. Pharmacological Inhibition and Genetic Knockdown of Exchange Protein Directly Activated by cAMP 1 Reduce Pancreatic Cancer Metastasis In Vivo
      Muayad Almahariq, Celia Chao, Fang C. Mei, Mark R. Hellmich, Igor Patrikeev, Massoud Motamedi and Xiaodong Cheng
      Molecular Pharmacology February 2015, 87 (2) 142-149; DOI: https://doi.org/10.1124/mol.114.095158

  11. Coleman, Nicole

    1. A Novel Pan-Negative-Gating Modulator of KCa2/3 Channels, Fluoro-Di-Benzoate, RA-2, Inhibits Endothelium-Derived Hyperpolarization–Type Relaxation in Coronary Artery and Produces Bradycardia In Vivo
      Aida Oliván-Viguera, Marta Sofía Valero, Nicole Coleman, Brandon M. Brown, Celia Laría, María Divina Murillo, José A. Gálvez, María D. Díaz-de-Villegas, Heike Wulff, Ramón Badorrey and Ralf Köhler
      Molecular Pharmacology February 2015, 87 (2) 338-348; DOI: https://doi.org/10.1124/mol.114.095745

  12. Corzo, Cesar A.

    1. Antiproliferation Activity of a Small Molecule Repressor of Liver Receptor Homolog 1
      Cesar A. Corzo, Yelenis Mari, Mi Ra Chang, Tanya Khan, Dana Kuruvilla, Philippe Nuhant, Naresh Kumar, Graham M. West, Derek R. Duckett, William R. Roush and Patrick R. Griffin
      Molecular Pharmacology February 2015, 87 (2) 296-304; DOI: https://doi.org/10.1124/mol.114.095554

  13. Cromie, K. D.

    1. Potent and Efficacious Inhibition of CXCR2 Signaling by Biparatopic Nanobodies Combining Two Distinct Modes of Action
      M. E. Bradley, B. Dombrecht, J. Manini, J. Willis, D. Vlerick, S. De Taeye, K. Van den Heede, A. Roobrouck, E. Grot, T. C. Kent, T. Laeremans, S. Steffensen, G. Van Heeke, Z. Brown, S. J. Charlton and K. D. Cromie
      Molecular Pharmacology February 2015, 87 (2) 251-262; DOI: https://doi.org/10.1124/mol.114.094821

  14. Cuny, Hartmut

    1. Novel Mechanism of Voltage-Gated N-type (Cav2.2) Calcium Channel Inhibition Revealed through α-Conotoxin Vc1.1 Activation of the GABAB Receptor
      Thuan G. Huynh, Hartmut Cuny, Paul A. Slesinger and David J. Adams
      Molecular Pharmacology February 2015, 87 (2) 240-250; DOI: https://doi.org/10.1124/mol.114.096156

D

  1. D’Amico, Massimo

    1. New Pyrimido-Indole Compound CD-160130 Preferentially Inhibits the KV11.1B Isoform and Produces Antileukemic Effects without Cardiotoxicity
      Luca Gasparoli, Massimo D’Amico, Marika Masselli, Serena Pillozzi, Rachel Caves, Rawan Khuwaileh, Wolfgang Tiedke, Kenneth Mugridge, Alessandro Pratesi, John S. Mitcheson, Giuseppe Basso, Andrea Becchetti and Annarosa Arcangeli
      Molecular Pharmacology February 2015, 87 (2) 183-196; DOI: https://doi.org/10.1124/mol.114.094920

  2. Das, Swadesh K.

    1. Reversing Translational Suppression and Induction of Toxicity in Pancreatic Cancer Cells Using a Chemoprevention Gene Therapy Approach
      Siddik Sarkar, Bridget A. Quinn, Xuening Shen, Paul Dent, Swadesh K. Das, Luni Emdad, Devanand Sarkar and Paul B. Fisher
      Molecular Pharmacology February 2015, 87 (2) 286-295; DOI: https://doi.org/10.1124/mol.114.094375

  3. Dent, Paul

    1. Reversing Translational Suppression and Induction of Toxicity in Pancreatic Cancer Cells Using a Chemoprevention Gene Therapy Approach
      Siddik Sarkar, Bridget A. Quinn, Xuening Shen, Paul Dent, Swadesh K. Das, Luni Emdad, Devanand Sarkar and Paul B. Fisher
      Molecular Pharmacology February 2015, 87 (2) 286-295; DOI: https://doi.org/10.1124/mol.114.094375

  4. De Taeye, S.

    1. Potent and Efficacious Inhibition of CXCR2 Signaling by Biparatopic Nanobodies Combining Two Distinct Modes of Action
      M. E. Bradley, B. Dombrecht, J. Manini, J. Willis, D. Vlerick, S. De Taeye, K. Van den Heede, A. Roobrouck, E. Grot, T. C. Kent, T. Laeremans, S. Steffensen, G. Van Heeke, Z. Brown, S. J. Charlton and K. D. Cromie
      Molecular Pharmacology February 2015, 87 (2) 251-262; DOI: https://doi.org/10.1124/mol.114.094821

  5. Díaz-de-Villegas, María D.

    1. A Novel Pan-Negative-Gating Modulator of KCa2/3 Channels, Fluoro-Di-Benzoate, RA-2, Inhibits Endothelium-Derived Hyperpolarization–Type Relaxation in Coronary Artery and Produces Bradycardia In Vivo
      Aida Oliván-Viguera, Marta Sofía Valero, Nicole Coleman, Brandon M. Brown, Celia Laría, María Divina Murillo, José A. Gálvez, María D. Díaz-de-Villegas, Heike Wulff, Ramón Badorrey and Ralf Köhler
      Molecular Pharmacology February 2015, 87 (2) 338-348; DOI: https://doi.org/10.1124/mol.114.095745

  6. Diederich, Wibke E.

    1. The Inverse Agonist DG172 Triggers a PPARβ/δ-Independent Myeloid Lineage Shift and Promotes GM-CSF/IL-4-Induced Dendritic Cell Differentiation
      Sonja Lieber, Frithjof Scheer, Florian Finkernagel, Wolfgang Meissner, Gavin Giehl, Cornelia Brendel, Wibke E. Diederich, Sabine Müller-Brüsselbach and Rolf Müller
      Molecular Pharmacology February 2015, 87 (2) 162-173; DOI: https://doi.org/10.1124/mol.114.094672

  7. Dillehay, Kelsey L.

    1. A Peptide Mimicking a Region in Proliferating Cell Nuclear Antigen Specific to Key Protein Interactions Is Cytotoxic to Breast Cancer
      Shanna J. Smith, Long Gu, Elizabeth A. Phipps, Lacey E. Dobrolecki, Karla S. Mabrey, Pattie Gulley, Kelsey L. Dillehay, Zhongyun Dong, Gregg B. Fields, Yun-Ru Chen, David Ann, Robert J. Hickey and Linda H. Malkas
      Molecular Pharmacology February 2015, 87 (2) 263-276; DOI: https://doi.org/10.1124/mol.114.093211

  8. Divina Murillo, María

    1. A Novel Pan-Negative-Gating Modulator of KCa2/3 Channels, Fluoro-Di-Benzoate, RA-2, Inhibits Endothelium-Derived Hyperpolarization–Type Relaxation in Coronary Artery and Produces Bradycardia In Vivo
      Aida Oliván-Viguera, Marta Sofía Valero, Nicole Coleman, Brandon M. Brown, Celia Laría, María Divina Murillo, José A. Gálvez, María D. Díaz-de-Villegas, Heike Wulff, Ramón Badorrey and Ralf Köhler
      Molecular Pharmacology February 2015, 87 (2) 338-348; DOI: https://doi.org/10.1124/mol.114.095745

  9. Dobrolecki, Lacey E.

    1. A Peptide Mimicking a Region in Proliferating Cell Nuclear Antigen Specific to Key Protein Interactions Is Cytotoxic to Breast Cancer
      Shanna J. Smith, Long Gu, Elizabeth A. Phipps, Lacey E. Dobrolecki, Karla S. Mabrey, Pattie Gulley, Kelsey L. Dillehay, Zhongyun Dong, Gregg B. Fields, Yun-Ru Chen, David Ann, Robert J. Hickey and Linda H. Malkas
      Molecular Pharmacology February 2015, 87 (2) 263-276; DOI: https://doi.org/10.1124/mol.114.093211

  10. Domaoal, Robert A.

    1. An Integrated Biological Approach to Guide the Development of Metal-Chelating Inhibitors of Influenza Virus PA Endonuclease
      Annelies Stevaert, Salvatore Nurra, Nicolino Pala, Mauro Carcelli, Dominga Rogolino, Caitlin Shepard, Robert A. Domaoal, Baek Kim, Mercedes Alfonso-Prieto, Salvatore A. E. Marras, Mario Sechi and Lieve Naesens
      Molecular Pharmacology February 2015, 87 (2) 323-337; DOI: https://doi.org/10.1124/mol.114.095588

  11. Dombrecht, B.

    1. Potent and Efficacious Inhibition of CXCR2 Signaling by Biparatopic Nanobodies Combining Two Distinct Modes of Action
      M. E. Bradley, B. Dombrecht, J. Manini, J. Willis, D. Vlerick, S. De Taeye, K. Van den Heede, A. Roobrouck, E. Grot, T. C. Kent, T. Laeremans, S. Steffensen, G. Van Heeke, Z. Brown, S. J. Charlton and K. D. Cromie
      Molecular Pharmacology February 2015, 87 (2) 251-262; DOI: https://doi.org/10.1124/mol.114.094821

  12. Dong, Zhongyun

    1. A Peptide Mimicking a Region in Proliferating Cell Nuclear Antigen Specific to Key Protein Interactions Is Cytotoxic to Breast Cancer
      Shanna J. Smith, Long Gu, Elizabeth A. Phipps, Lacey E. Dobrolecki, Karla S. Mabrey, Pattie Gulley, Kelsey L. Dillehay, Zhongyun Dong, Gregg B. Fields, Yun-Ru Chen, David Ann, Robert J. Hickey and Linda H. Malkas
      Molecular Pharmacology February 2015, 87 (2) 263-276; DOI: https://doi.org/10.1124/mol.114.093211

  13. Donnelly, Siobhan M.

    1. Insulin-Like Growth Factor-1 Receptor Signaling Increases the Invasive Potential of Human Epidermal Growth Factor Receptor 2–Overexpressing Breast Cancer Cells via Src-Focal Adhesion Kinase and Forkhead Box Protein M1
      Eduardo Sanabria-Figueroa, Siobhan M. Donnelly, Kevin C. Foy, Meghan C. Buss, Robert C. Castellino, Elisavet Paplomata, Latonia Taliaferro-Smith, Pravin T.P. Kaumaya and Rita Nahta
      Molecular Pharmacology February 2015, 87 (2) 150-161; DOI: https://doi.org/10.1124/mol.114.095380

  14. Dryer, Stuart E.

    1. RETRACTION: STAT3 Regulates Steady-State Expression of Synaptopodin in Cultured Mouse Podocytes
      Mousa Abkhezr and Stuart E. Dryer
      Molecular Pharmacology February 2015, 87 (2) 231-239; DOI: https://doi.org/10.1124/mol.114.094508

  15. Du, Fang

    1. Reporting Sodium Channel Activity Using Calcium Flux: Pharmacological Promiscuity of Cardiac Nav1.5
      Hongkang Zhang, Beiyan Zou, Fang Du, Kaiping Xu and Min Li
      Molecular Pharmacology February 2015, 87 (2) 207-217; DOI: https://doi.org/10.1124/mol.114.094789

  16. Duckett, Derek R.

    1. Antiproliferation Activity of a Small Molecule Repressor of Liver Receptor Homolog 1
      Cesar A. Corzo, Yelenis Mari, Mi Ra Chang, Tanya Khan, Dana Kuruvilla, Philippe Nuhant, Naresh Kumar, Graham M. West, Derek R. Duckett, William R. Roush and Patrick R. Griffin
      Molecular Pharmacology February 2015, 87 (2) 296-304; DOI: https://doi.org/10.1124/mol.114.095554

E

  1. Emdad, Luni

    1. Reversing Translational Suppression and Induction of Toxicity in Pancreatic Cancer Cells Using a Chemoprevention Gene Therapy Approach
      Siddik Sarkar, Bridget A. Quinn, Xuening Shen, Paul Dent, Swadesh K. Das, Luni Emdad, Devanand Sarkar and Paul B. Fisher
      Molecular Pharmacology February 2015, 87 (2) 286-295; DOI: https://doi.org/10.1124/mol.114.094375

F

  1. Fields, Gregg B.

    1. A Peptide Mimicking a Region in Proliferating Cell Nuclear Antigen Specific to Key Protein Interactions Is Cytotoxic to Breast Cancer
      Shanna J. Smith, Long Gu, Elizabeth A. Phipps, Lacey E. Dobrolecki, Karla S. Mabrey, Pattie Gulley, Kelsey L. Dillehay, Zhongyun Dong, Gregg B. Fields, Yun-Ru Chen, David Ann, Robert J. Hickey and Linda H. Malkas
      Molecular Pharmacology February 2015, 87 (2) 263-276; DOI: https://doi.org/10.1124/mol.114.093211

  2. Finkernagel, Florian

    1. The Inverse Agonist DG172 Triggers a PPARβ/δ-Independent Myeloid Lineage Shift and Promotes GM-CSF/IL-4-Induced Dendritic Cell Differentiation
      Sonja Lieber, Frithjof Scheer, Florian Finkernagel, Wolfgang Meissner, Gavin Giehl, Cornelia Brendel, Wibke E. Diederich, Sabine Müller-Brüsselbach and Rolf Müller
      Molecular Pharmacology February 2015, 87 (2) 162-173; DOI: https://doi.org/10.1124/mol.114.094672

  3. Fisher, Paul B.

    1. Reversing Translational Suppression and Induction of Toxicity in Pancreatic Cancer Cells Using a Chemoprevention Gene Therapy Approach
      Siddik Sarkar, Bridget A. Quinn, Xuening Shen, Paul Dent, Swadesh K. Das, Luni Emdad, Devanand Sarkar and Paul B. Fisher
      Molecular Pharmacology February 2015, 87 (2) 286-295; DOI: https://doi.org/10.1124/mol.114.094375

  4. Foy, Kevin C.

    1. Insulin-Like Growth Factor-1 Receptor Signaling Increases the Invasive Potential of Human Epidermal Growth Factor Receptor 2–Overexpressing Breast Cancer Cells via Src-Focal Adhesion Kinase and Forkhead Box Protein M1
      Eduardo Sanabria-Figueroa, Siobhan M. Donnelly, Kevin C. Foy, Meghan C. Buss, Robert C. Castellino, Elisavet Paplomata, Latonia Taliaferro-Smith, Pravin T.P. Kaumaya and Rita Nahta
      Molecular Pharmacology February 2015, 87 (2) 150-161; DOI: https://doi.org/10.1124/mol.114.095380

G

  1. Gálvez, José A.

    1. A Novel Pan-Negative-Gating Modulator of KCa2/3 Channels, Fluoro-Di-Benzoate, RA-2, Inhibits Endothelium-Derived Hyperpolarization–Type Relaxation in Coronary Artery and Produces Bradycardia In Vivo
      Aida Oliván-Viguera, Marta Sofía Valero, Nicole Coleman, Brandon M. Brown, Celia Laría, María Divina Murillo, José A. Gálvez, María D. Díaz-de-Villegas, Heike Wulff, Ramón Badorrey and Ralf Köhler
      Molecular Pharmacology February 2015, 87 (2) 338-348; DOI: https://doi.org/10.1124/mol.114.095745

  2. Gasparoli, Luca

    1. New Pyrimido-Indole Compound CD-160130 Preferentially Inhibits the KV11.1B Isoform and Produces Antileukemic Effects without Cardiotoxicity
      Luca Gasparoli, Massimo D’Amico, Marika Masselli, Serena Pillozzi, Rachel Caves, Rawan Khuwaileh, Wolfgang Tiedke, Kenneth Mugridge, Alessandro Pratesi, John S. Mitcheson, Giuseppe Basso, Andrea Becchetti and Annarosa Arcangeli
      Molecular Pharmacology February 2015, 87 (2) 183-196; DOI: https://doi.org/10.1124/mol.114.094920

  3. Giehl, Gavin

    1. The Inverse Agonist DG172 Triggers a PPARβ/δ-Independent Myeloid Lineage Shift and Promotes GM-CSF/IL-4-Induced Dendritic Cell Differentiation
      Sonja Lieber, Frithjof Scheer, Florian Finkernagel, Wolfgang Meissner, Gavin Giehl, Cornelia Brendel, Wibke E. Diederich, Sabine Müller-Brüsselbach and Rolf Müller
      Molecular Pharmacology February 2015, 87 (2) 162-173; DOI: https://doi.org/10.1124/mol.114.094672

  4. Griffin, Patrick R.

    1. Antiproliferation Activity of a Small Molecule Repressor of Liver Receptor Homolog 1
      Cesar A. Corzo, Yelenis Mari, Mi Ra Chang, Tanya Khan, Dana Kuruvilla, Philippe Nuhant, Naresh Kumar, Graham M. West, Derek R. Duckett, William R. Roush and Patrick R. Griffin
      Molecular Pharmacology February 2015, 87 (2) 296-304; DOI: https://doi.org/10.1124/mol.114.095554

  5. Grot, E.

    1. Potent and Efficacious Inhibition of CXCR2 Signaling by Biparatopic Nanobodies Combining Two Distinct Modes of Action
      M. E. Bradley, B. Dombrecht, J. Manini, J. Willis, D. Vlerick, S. De Taeye, K. Van den Heede, A. Roobrouck, E. Grot, T. C. Kent, T. Laeremans, S. Steffensen, G. Van Heeke, Z. Brown, S. J. Charlton and K. D. Cromie
      Molecular Pharmacology February 2015, 87 (2) 251-262; DOI: https://doi.org/10.1124/mol.114.094821

  6. Gu, Long

    1. A Peptide Mimicking a Region in Proliferating Cell Nuclear Antigen Specific to Key Protein Interactions Is Cytotoxic to Breast Cancer
      Shanna J. Smith, Long Gu, Elizabeth A. Phipps, Lacey E. Dobrolecki, Karla S. Mabrey, Pattie Gulley, Kelsey L. Dillehay, Zhongyun Dong, Gregg B. Fields, Yun-Ru Chen, David Ann, Robert J. Hickey and Linda H. Malkas
      Molecular Pharmacology February 2015, 87 (2) 263-276; DOI: https://doi.org/10.1124/mol.114.093211

  7. Gulley, Pattie

    1. A Peptide Mimicking a Region in Proliferating Cell Nuclear Antigen Specific to Key Protein Interactions Is Cytotoxic to Breast Cancer
      Shanna J. Smith, Long Gu, Elizabeth A. Phipps, Lacey E. Dobrolecki, Karla S. Mabrey, Pattie Gulley, Kelsey L. Dillehay, Zhongyun Dong, Gregg B. Fields, Yun-Ru Chen, David Ann, Robert J. Hickey and Linda H. Malkas
      Molecular Pharmacology February 2015, 87 (2) 263-276; DOI: https://doi.org/10.1124/mol.114.093211

  8. Gutiérrez-de-Terán, Hugo

    1. Sodium Ion Binding Pocket Mutations and Adenosine A2A Receptor Function
      Arnault Massink, Hugo Gutiérrez-de-Terán, Eelke B. Lenselink, Natalia V. Ortiz Zacarías, Lizi Xia, Laura H. Heitman, Vsevolod Katritch, Raymond C. Stevens and Adriaan P. IJzerman
      Molecular Pharmacology February 2015, 87 (2) 305-313; DOI: https://doi.org/10.1124/mol.114.095737

H

  1. Hashimoto, Hana

    1. Modulation of Peroxisome Proliferator-Activated Receptor-α Activity by Bile Acids Causes Circadian Changes in the Intestinal Expression of Octn1/Slc22a4 in Mice
      Erika Wada, Satoru Koyanagi, Naoki Kusunose, Takahiro Akamine, Hiroaki Masui, Hana Hashimoto, Naoya Matsunaga and Shigehiro Ohdo
      Molecular Pharmacology February 2015, 87 (2) 314-322; DOI: https://doi.org/10.1124/mol.114.094979

  2. Heitman, Laura H.

    1. Sodium Ion Binding Pocket Mutations and Adenosine A2A Receptor Function
      Arnault Massink, Hugo Gutiérrez-de-Terán, Eelke B. Lenselink, Natalia V. Ortiz Zacarías, Lizi Xia, Laura H. Heitman, Vsevolod Katritch, Raymond C. Stevens and Adriaan P. IJzerman
      Molecular Pharmacology February 2015, 87 (2) 305-313; DOI: https://doi.org/10.1124/mol.114.095737

  3. Hellmich, Mark R.

    1. Pharmacological Inhibition and Genetic Knockdown of Exchange Protein Directly Activated by cAMP 1 Reduce Pancreatic Cancer Metastasis In Vivo
      Muayad Almahariq, Celia Chao, Fang C. Mei, Mark R. Hellmich, Igor Patrikeev, Massoud Motamedi and Xiaodong Cheng
      Molecular Pharmacology February 2015, 87 (2) 142-149; DOI: https://doi.org/10.1124/mol.114.095158

  4. Hickey, Robert J.

    1. A Peptide Mimicking a Region in Proliferating Cell Nuclear Antigen Specific to Key Protein Interactions Is Cytotoxic to Breast Cancer
      Shanna J. Smith, Long Gu, Elizabeth A. Phipps, Lacey E. Dobrolecki, Karla S. Mabrey, Pattie Gulley, Kelsey L. Dillehay, Zhongyun Dong, Gregg B. Fields, Yun-Ru Chen, David Ann, Robert J. Hickey and Linda H. Malkas
      Molecular Pharmacology February 2015, 87 (2) 263-276; DOI: https://doi.org/10.1124/mol.114.093211

  5. Honda, Takeshi

    1. Signaling Mechanism Underlying the Promotion of Keratinocyte Migration by Angiotensin II
      Hiroki Sakai, Kenji Matsuura, Yoshie Tanaka, Takeshi Honda, Teruo Nishida and Makoto Inui
      Molecular Pharmacology February 2015, 87 (2) 277-285; DOI: https://doi.org/10.1124/mol.114.096461

  6. Hsiao, Nai-Wan

    1. Phage Display–Mediated Discovery of Novel Tyrosinase-Targeting Tetrapeptide Inhibitors Reveals the Significance of N-Terminal Preference of Cysteine Residues and Their Functional Sulfur Atom
      Yu-Ching Lee, Nai-Wan Hsiao, Tien-Sheng Tseng, Wang-Chuan Chen, Hui-Hsiung Lin, Sy-Jye Leu, Ei-Wen Yang and Keng-Chang Tsai
      Molecular Pharmacology February 2015, 87 (2) 218-230; DOI: https://doi.org/10.1124/mol.114.094185

  7. Hu, Liping

    1. An Overview of Hedgehog Signaling in Fibrosis
      Liping Hu, Xiangyang Lin, Hong Lu, Bicheng Chen and Yongheng Bai
      Molecular Pharmacology February 2015, 87 (2) 174-182; DOI: https://doi.org/10.1124/mol.114.095141

  8. Hurst, Dow P.

    1. (4-(Bis(4-Fluorophenyl)Methyl)Piperazin-1-yl)(Cyclohexyl)Methanone Hydrochloride (LDK1229): A New Cannabinoid CB1 Receptor Inverse Agonist from the Class of Benzhydryl Piperazine Analogs
      Mariam M. Mahmoud, Teresa Olszewska, Hui Liu, Derek M. Shore, Dow P. Hurst, Patricia H. Reggio, Dai Lu and Debra A. Kendall
      Molecular Pharmacology February 2015, 87 (2) 197-206; DOI: https://doi.org/10.1124/mol.114.095471

  9. Huynh, Thuan G.

    1. Novel Mechanism of Voltage-Gated N-type (Cav2.2) Calcium Channel Inhibition Revealed through α-Conotoxin Vc1.1 Activation of the GABAB Receptor
      Thuan G. Huynh, Hartmut Cuny, Paul A. Slesinger and David J. Adams
      Molecular Pharmacology February 2015, 87 (2) 240-250; DOI: https://doi.org/10.1124/mol.114.096156

I

  1. IJzerman, Adriaan P.

    1. Sodium Ion Binding Pocket Mutations and Adenosine A2A Receptor Function
      Arnault Massink, Hugo Gutiérrez-de-Terán, Eelke B. Lenselink, Natalia V. Ortiz Zacarías, Lizi Xia, Laura H. Heitman, Vsevolod Katritch, Raymond C. Stevens and Adriaan P. IJzerman
      Molecular Pharmacology February 2015, 87 (2) 305-313; DOI: https://doi.org/10.1124/mol.114.095737

  2. Inui, Makoto

    1. Signaling Mechanism Underlying the Promotion of Keratinocyte Migration by Angiotensin II
      Hiroki Sakai, Kenji Matsuura, Yoshie Tanaka, Takeshi Honda, Teruo Nishida and Makoto Inui
      Molecular Pharmacology February 2015, 87 (2) 277-285; DOI: https://doi.org/10.1124/mol.114.096461

K

  1. Katritch, Vsevolod

    1. Sodium Ion Binding Pocket Mutations and Adenosine A2A Receptor Function
      Arnault Massink, Hugo Gutiérrez-de-Terán, Eelke B. Lenselink, Natalia V. Ortiz Zacarías, Lizi Xia, Laura H. Heitman, Vsevolod Katritch, Raymond C. Stevens and Adriaan P. IJzerman
      Molecular Pharmacology February 2015, 87 (2) 305-313; DOI: https://doi.org/10.1124/mol.114.095737

  2. Kaumaya, Pravin T.P.

    1. Insulin-Like Growth Factor-1 Receptor Signaling Increases the Invasive Potential of Human Epidermal Growth Factor Receptor 2–Overexpressing Breast Cancer Cells via Src-Focal Adhesion Kinase and Forkhead Box Protein M1
      Eduardo Sanabria-Figueroa, Siobhan M. Donnelly, Kevin C. Foy, Meghan C. Buss, Robert C. Castellino, Elisavet Paplomata, Latonia Taliaferro-Smith, Pravin T.P. Kaumaya and Rita Nahta
      Molecular Pharmacology February 2015, 87 (2) 150-161; DOI: https://doi.org/10.1124/mol.114.095380

  3. Kendall, Debra A.

    1. (4-(Bis(4-Fluorophenyl)Methyl)Piperazin-1-yl)(Cyclohexyl)Methanone Hydrochloride (LDK1229): A New Cannabinoid CB1 Receptor Inverse Agonist from the Class of Benzhydryl Piperazine Analogs
      Mariam M. Mahmoud, Teresa Olszewska, Hui Liu, Derek M. Shore, Dow P. Hurst, Patricia H. Reggio, Dai Lu and Debra A. Kendall
      Molecular Pharmacology February 2015, 87 (2) 197-206; DOI: https://doi.org/10.1124/mol.114.095471

  4. Kent, T. C.

    1. Potent and Efficacious Inhibition of CXCR2 Signaling by Biparatopic Nanobodies Combining Two Distinct Modes of Action
      M. E. Bradley, B. Dombrecht, J. Manini, J. Willis, D. Vlerick, S. De Taeye, K. Van den Heede, A. Roobrouck, E. Grot, T. C. Kent, T. Laeremans, S. Steffensen, G. Van Heeke, Z. Brown, S. J. Charlton and K. D. Cromie
      Molecular Pharmacology February 2015, 87 (2) 251-262; DOI: https://doi.org/10.1124/mol.114.094821

  5. Khan, Tanya

    1. Antiproliferation Activity of a Small Molecule Repressor of Liver Receptor Homolog 1
      Cesar A. Corzo, Yelenis Mari, Mi Ra Chang, Tanya Khan, Dana Kuruvilla, Philippe Nuhant, Naresh Kumar, Graham M. West, Derek R. Duckett, William R. Roush and Patrick R. Griffin
      Molecular Pharmacology February 2015, 87 (2) 296-304; DOI: https://doi.org/10.1124/mol.114.095554

  6. Khuwaileh, Rawan

    1. New Pyrimido-Indole Compound CD-160130 Preferentially Inhibits the KV11.1B Isoform and Produces Antileukemic Effects without Cardiotoxicity
      Luca Gasparoli, Massimo D’Amico, Marika Masselli, Serena Pillozzi, Rachel Caves, Rawan Khuwaileh, Wolfgang Tiedke, Kenneth Mugridge, Alessandro Pratesi, John S. Mitcheson, Giuseppe Basso, Andrea Becchetti and Annarosa Arcangeli
      Molecular Pharmacology February 2015, 87 (2) 183-196; DOI: https://doi.org/10.1124/mol.114.094920

  7. Kim, Baek

    1. An Integrated Biological Approach to Guide the Development of Metal-Chelating Inhibitors of Influenza Virus PA Endonuclease
      Annelies Stevaert, Salvatore Nurra, Nicolino Pala, Mauro Carcelli, Dominga Rogolino, Caitlin Shepard, Robert A. Domaoal, Baek Kim, Mercedes Alfonso-Prieto, Salvatore A. E. Marras, Mario Sechi and Lieve Naesens
      Molecular Pharmacology February 2015, 87 (2) 323-337; DOI: https://doi.org/10.1124/mol.114.095588

  8. Köhler, Ralf

    1. A Novel Pan-Negative-Gating Modulator of KCa2/3 Channels, Fluoro-Di-Benzoate, RA-2, Inhibits Endothelium-Derived Hyperpolarization–Type Relaxation in Coronary Artery and Produces Bradycardia In Vivo
      Aida Oliván-Viguera, Marta Sofía Valero, Nicole Coleman, Brandon M. Brown, Celia Laría, María Divina Murillo, José A. Gálvez, María D. Díaz-de-Villegas, Heike Wulff, Ramón Badorrey and Ralf Köhler
      Molecular Pharmacology February 2015, 87 (2) 338-348; DOI: https://doi.org/10.1124/mol.114.095745

  9. Koyanagi, Satoru

    1. Modulation of Peroxisome Proliferator-Activated Receptor-α Activity by Bile Acids Causes Circadian Changes in the Intestinal Expression of Octn1/Slc22a4 in Mice
      Erika Wada, Satoru Koyanagi, Naoki Kusunose, Takahiro Akamine, Hiroaki Masui, Hana Hashimoto, Naoya Matsunaga and Shigehiro Ohdo
      Molecular Pharmacology February 2015, 87 (2) 314-322; DOI: https://doi.org/10.1124/mol.114.094979

  10. Krasel, Cornelius

    1. Engineered Hyperphosphorylation of the β2-Adrenoceptor Prolongs Arrestin-3 Binding and Induces Arrestin Internalization
      Diana Zindel, Adrian J. Butcher, Suleiman Al-Sabah, Peter Lanzerstorfer, Julian Weghuber, Andrew B. Tobin, Moritz Bünemann and Cornelius Krasel
      Molecular Pharmacology February 2015, 87 (2) 349-362; DOI: https://doi.org/10.1124/mol.114.095422

  11. Kumar, Naresh

    1. Antiproliferation Activity of a Small Molecule Repressor of Liver Receptor Homolog 1
      Cesar A. Corzo, Yelenis Mari, Mi Ra Chang, Tanya Khan, Dana Kuruvilla, Philippe Nuhant, Naresh Kumar, Graham M. West, Derek R. Duckett, William R. Roush and Patrick R. Griffin
      Molecular Pharmacology February 2015, 87 (2) 296-304; DOI: https://doi.org/10.1124/mol.114.095554

  12. Kuruvilla, Dana

    1. Antiproliferation Activity of a Small Molecule Repressor of Liver Receptor Homolog 1
      Cesar A. Corzo, Yelenis Mari, Mi Ra Chang, Tanya Khan, Dana Kuruvilla, Philippe Nuhant, Naresh Kumar, Graham M. West, Derek R. Duckett, William R. Roush and Patrick R. Griffin
      Molecular Pharmacology February 2015, 87 (2) 296-304; DOI: https://doi.org/10.1124/mol.114.095554

  13. Kusunose, Naoki

    1. Modulation of Peroxisome Proliferator-Activated Receptor-α Activity by Bile Acids Causes Circadian Changes in the Intestinal Expression of Octn1/Slc22a4 in Mice
      Erika Wada, Satoru Koyanagi, Naoki Kusunose, Takahiro Akamine, Hiroaki Masui, Hana Hashimoto, Naoya Matsunaga and Shigehiro Ohdo
      Molecular Pharmacology February 2015, 87 (2) 314-322; DOI: https://doi.org/10.1124/mol.114.094979

L

  1. Laeremans, T.

    1. Potent and Efficacious Inhibition of CXCR2 Signaling by Biparatopic Nanobodies Combining Two Distinct Modes of Action
      M. E. Bradley, B. Dombrecht, J. Manini, J. Willis, D. Vlerick, S. De Taeye, K. Van den Heede, A. Roobrouck, E. Grot, T. C. Kent, T. Laeremans, S. Steffensen, G. Van Heeke, Z. Brown, S. J. Charlton and K. D. Cromie
      Molecular Pharmacology February 2015, 87 (2) 251-262; DOI: https://doi.org/10.1124/mol.114.094821

  2. Lanzerstorfer, Peter

    1. Engineered Hyperphosphorylation of the β2-Adrenoceptor Prolongs Arrestin-3 Binding and Induces Arrestin Internalization
      Diana Zindel, Adrian J. Butcher, Suleiman Al-Sabah, Peter Lanzerstorfer, Julian Weghuber, Andrew B. Tobin, Moritz Bünemann and Cornelius Krasel
      Molecular Pharmacology February 2015, 87 (2) 349-362; DOI: https://doi.org/10.1124/mol.114.095422

  3. Laría, Celia

    1. A Novel Pan-Negative-Gating Modulator of KCa2/3 Channels, Fluoro-Di-Benzoate, RA-2, Inhibits Endothelium-Derived Hyperpolarization–Type Relaxation in Coronary Artery and Produces Bradycardia In Vivo
      Aida Oliván-Viguera, Marta Sofía Valero, Nicole Coleman, Brandon M. Brown, Celia Laría, María Divina Murillo, José A. Gálvez, María D. Díaz-de-Villegas, Heike Wulff, Ramón Badorrey and Ralf Köhler
      Molecular Pharmacology February 2015, 87 (2) 338-348; DOI: https://doi.org/10.1124/mol.114.095745

  4. Lee, Yu-Ching

    1. Phage Display–Mediated Discovery of Novel Tyrosinase-Targeting Tetrapeptide Inhibitors Reveals the Significance of N-Terminal Preference of Cysteine Residues and Their Functional Sulfur Atom
      Yu-Ching Lee, Nai-Wan Hsiao, Tien-Sheng Tseng, Wang-Chuan Chen, Hui-Hsiung Lin, Sy-Jye Leu, Ei-Wen Yang and Keng-Chang Tsai
      Molecular Pharmacology February 2015, 87 (2) 218-230; DOI: https://doi.org/10.1124/mol.114.094185

  5. Lenselink, Eelke B.

    1. Sodium Ion Binding Pocket Mutations and Adenosine A2A Receptor Function
      Arnault Massink, Hugo Gutiérrez-de-Terán, Eelke B. Lenselink, Natalia V. Ortiz Zacarías, Lizi Xia, Laura H. Heitman, Vsevolod Katritch, Raymond C. Stevens and Adriaan P. IJzerman
      Molecular Pharmacology February 2015, 87 (2) 305-313; DOI: https://doi.org/10.1124/mol.114.095737

  6. Leu, Sy-Jye

    1. Phage Display–Mediated Discovery of Novel Tyrosinase-Targeting Tetrapeptide Inhibitors Reveals the Significance of N-Terminal Preference of Cysteine Residues and Their Functional Sulfur Atom
      Yu-Ching Lee, Nai-Wan Hsiao, Tien-Sheng Tseng, Wang-Chuan Chen, Hui-Hsiung Lin, Sy-Jye Leu, Ei-Wen Yang and Keng-Chang Tsai
      Molecular Pharmacology February 2015, 87 (2) 218-230; DOI: https://doi.org/10.1124/mol.114.094185

  7. Li, Min

    1. Reporting Sodium Channel Activity Using Calcium Flux: Pharmacological Promiscuity of Cardiac Nav1.5
      Hongkang Zhang, Beiyan Zou, Fang Du, Kaiping Xu and Min Li
      Molecular Pharmacology February 2015, 87 (2) 207-217; DOI: https://doi.org/10.1124/mol.114.094789

  8. Lieber, Sonja

    1. The Inverse Agonist DG172 Triggers a PPARβ/δ-Independent Myeloid Lineage Shift and Promotes GM-CSF/IL-4-Induced Dendritic Cell Differentiation
      Sonja Lieber, Frithjof Scheer, Florian Finkernagel, Wolfgang Meissner, Gavin Giehl, Cornelia Brendel, Wibke E. Diederich, Sabine Müller-Brüsselbach and Rolf Müller
      Molecular Pharmacology February 2015, 87 (2) 162-173; DOI: https://doi.org/10.1124/mol.114.094672

  9. Lin, Hui-Hsiung

    1. Phage Display–Mediated Discovery of Novel Tyrosinase-Targeting Tetrapeptide Inhibitors Reveals the Significance of N-Terminal Preference of Cysteine Residues and Their Functional Sulfur Atom
      Yu-Ching Lee, Nai-Wan Hsiao, Tien-Sheng Tseng, Wang-Chuan Chen, Hui-Hsiung Lin, Sy-Jye Leu, Ei-Wen Yang and Keng-Chang Tsai
      Molecular Pharmacology February 2015, 87 (2) 218-230; DOI: https://doi.org/10.1124/mol.114.094185

  10. Lin, Xiangyang

    1. An Overview of Hedgehog Signaling in Fibrosis
      Liping Hu, Xiangyang Lin, Hong Lu, Bicheng Chen and Yongheng Bai
      Molecular Pharmacology February 2015, 87 (2) 174-182; DOI: https://doi.org/10.1124/mol.114.095141

  11. Liu, Hui

    1. (4-(Bis(4-Fluorophenyl)Methyl)Piperazin-1-yl)(Cyclohexyl)Methanone Hydrochloride (LDK1229): A New Cannabinoid CB1 Receptor Inverse Agonist from the Class of Benzhydryl Piperazine Analogs
      Mariam M. Mahmoud, Teresa Olszewska, Hui Liu, Derek M. Shore, Dow P. Hurst, Patricia H. Reggio, Dai Lu and Debra A. Kendall
      Molecular Pharmacology February 2015, 87 (2) 197-206; DOI: https://doi.org/10.1124/mol.114.095471

  12. Lu, Dai

    1. (4-(Bis(4-Fluorophenyl)Methyl)Piperazin-1-yl)(Cyclohexyl)Methanone Hydrochloride (LDK1229): A New Cannabinoid CB1 Receptor Inverse Agonist from the Class of Benzhydryl Piperazine Analogs
      Mariam M. Mahmoud, Teresa Olszewska, Hui Liu, Derek M. Shore, Dow P. Hurst, Patricia H. Reggio, Dai Lu and Debra A. Kendall
      Molecular Pharmacology February 2015, 87 (2) 197-206; DOI: https://doi.org/10.1124/mol.114.095471

  13. Lu, Hong

    1. An Overview of Hedgehog Signaling in Fibrosis
      Liping Hu, Xiangyang Lin, Hong Lu, Bicheng Chen and Yongheng Bai
      Molecular Pharmacology February 2015, 87 (2) 174-182; DOI: https://doi.org/10.1124/mol.114.095141

M

  1. Mabrey, Karla S.

    1. A Peptide Mimicking a Region in Proliferating Cell Nuclear Antigen Specific to Key Protein Interactions Is Cytotoxic to Breast Cancer
      Shanna J. Smith, Long Gu, Elizabeth A. Phipps, Lacey E. Dobrolecki, Karla S. Mabrey, Pattie Gulley, Kelsey L. Dillehay, Zhongyun Dong, Gregg B. Fields, Yun-Ru Chen, David Ann, Robert J. Hickey and Linda H. Malkas
      Molecular Pharmacology February 2015, 87 (2) 263-276; DOI: https://doi.org/10.1124/mol.114.093211

  2. Mahmoud, Mariam M.

    1. (4-(Bis(4-Fluorophenyl)Methyl)Piperazin-1-yl)(Cyclohexyl)Methanone Hydrochloride (LDK1229): A New Cannabinoid CB1 Receptor Inverse Agonist from the Class of Benzhydryl Piperazine Analogs
      Mariam M. Mahmoud, Teresa Olszewska, Hui Liu, Derek M. Shore, Dow P. Hurst, Patricia H. Reggio, Dai Lu and Debra A. Kendall
      Molecular Pharmacology February 2015, 87 (2) 197-206; DOI: https://doi.org/10.1124/mol.114.095471

  3. Malkas, Linda H.

    1. A Peptide Mimicking a Region in Proliferating Cell Nuclear Antigen Specific to Key Protein Interactions Is Cytotoxic to Breast Cancer
      Shanna J. Smith, Long Gu, Elizabeth A. Phipps, Lacey E. Dobrolecki, Karla S. Mabrey, Pattie Gulley, Kelsey L. Dillehay, Zhongyun Dong, Gregg B. Fields, Yun-Ru Chen, David Ann, Robert J. Hickey and Linda H. Malkas
      Molecular Pharmacology February 2015, 87 (2) 263-276; DOI: https://doi.org/10.1124/mol.114.093211

  4. Manini, J.

    1. Potent and Efficacious Inhibition of CXCR2 Signaling by Biparatopic Nanobodies Combining Two Distinct Modes of Action
      M. E. Bradley, B. Dombrecht, J. Manini, J. Willis, D. Vlerick, S. De Taeye, K. Van den Heede, A. Roobrouck, E. Grot, T. C. Kent, T. Laeremans, S. Steffensen, G. Van Heeke, Z. Brown, S. J. Charlton and K. D. Cromie
      Molecular Pharmacology February 2015, 87 (2) 251-262; DOI: https://doi.org/10.1124/mol.114.094821

  5. Mari, Yelenis

    1. Antiproliferation Activity of a Small Molecule Repressor of Liver Receptor Homolog 1
      Cesar A. Corzo, Yelenis Mari, Mi Ra Chang, Tanya Khan, Dana Kuruvilla, Philippe Nuhant, Naresh Kumar, Graham M. West, Derek R. Duckett, William R. Roush and Patrick R. Griffin
      Molecular Pharmacology February 2015, 87 (2) 296-304; DOI: https://doi.org/10.1124/mol.114.095554

  6. Marras, Salvatore A. E.

    1. An Integrated Biological Approach to Guide the Development of Metal-Chelating Inhibitors of Influenza Virus PA Endonuclease
      Annelies Stevaert, Salvatore Nurra, Nicolino Pala, Mauro Carcelli, Dominga Rogolino, Caitlin Shepard, Robert A. Domaoal, Baek Kim, Mercedes Alfonso-Prieto, Salvatore A. E. Marras, Mario Sechi and Lieve Naesens
      Molecular Pharmacology February 2015, 87 (2) 323-337; DOI: https://doi.org/10.1124/mol.114.095588

  7. Masselli, Marika

    1. New Pyrimido-Indole Compound CD-160130 Preferentially Inhibits the KV11.1B Isoform and Produces Antileukemic Effects without Cardiotoxicity
      Luca Gasparoli, Massimo D’Amico, Marika Masselli, Serena Pillozzi, Rachel Caves, Rawan Khuwaileh, Wolfgang Tiedke, Kenneth Mugridge, Alessandro Pratesi, John S. Mitcheson, Giuseppe Basso, Andrea Becchetti and Annarosa Arcangeli
      Molecular Pharmacology February 2015, 87 (2) 183-196; DOI: https://doi.org/10.1124/mol.114.094920

  8. Massink, Arnault

    1. Sodium Ion Binding Pocket Mutations and Adenosine A2A Receptor Function
      Arnault Massink, Hugo Gutiérrez-de-Terán, Eelke B. Lenselink, Natalia V. Ortiz Zacarías, Lizi Xia, Laura H. Heitman, Vsevolod Katritch, Raymond C. Stevens and Adriaan P. IJzerman
      Molecular Pharmacology February 2015, 87 (2) 305-313; DOI: https://doi.org/10.1124/mol.114.095737

  9. Masui, Hiroaki

    1. Modulation of Peroxisome Proliferator-Activated Receptor-α Activity by Bile Acids Causes Circadian Changes in the Intestinal Expression of Octn1/Slc22a4 in Mice
      Erika Wada, Satoru Koyanagi, Naoki Kusunose, Takahiro Akamine, Hiroaki Masui, Hana Hashimoto, Naoya Matsunaga and Shigehiro Ohdo
      Molecular Pharmacology February 2015, 87 (2) 314-322; DOI: https://doi.org/10.1124/mol.114.094979

  10. Matsunaga, Naoya

    1. Modulation of Peroxisome Proliferator-Activated Receptor-α Activity by Bile Acids Causes Circadian Changes in the Intestinal Expression of Octn1/Slc22a4 in Mice
      Erika Wada, Satoru Koyanagi, Naoki Kusunose, Takahiro Akamine, Hiroaki Masui, Hana Hashimoto, Naoya Matsunaga and Shigehiro Ohdo
      Molecular Pharmacology February 2015, 87 (2) 314-322; DOI: https://doi.org/10.1124/mol.114.094979

  11. Matsuura, Kenji

    1. Signaling Mechanism Underlying the Promotion of Keratinocyte Migration by Angiotensin II
      Hiroki Sakai, Kenji Matsuura, Yoshie Tanaka, Takeshi Honda, Teruo Nishida and Makoto Inui
      Molecular Pharmacology February 2015, 87 (2) 277-285; DOI: https://doi.org/10.1124/mol.114.096461

  12. Mei, Fang C.

    1. Pharmacological Inhibition and Genetic Knockdown of Exchange Protein Directly Activated by cAMP 1 Reduce Pancreatic Cancer Metastasis In Vivo
      Muayad Almahariq, Celia Chao, Fang C. Mei, Mark R. Hellmich, Igor Patrikeev, Massoud Motamedi and Xiaodong Cheng
      Molecular Pharmacology February 2015, 87 (2) 142-149; DOI: https://doi.org/10.1124/mol.114.095158

  13. Meissner, Wolfgang

    1. The Inverse Agonist DG172 Triggers a PPARβ/δ-Independent Myeloid Lineage Shift and Promotes GM-CSF/IL-4-Induced Dendritic Cell Differentiation
      Sonja Lieber, Frithjof Scheer, Florian Finkernagel, Wolfgang Meissner, Gavin Giehl, Cornelia Brendel, Wibke E. Diederich, Sabine Müller-Brüsselbach and Rolf Müller
      Molecular Pharmacology February 2015, 87 (2) 162-173; DOI: https://doi.org/10.1124/mol.114.094672

  14. Mitcheson, John S.

    1. New Pyrimido-Indole Compound CD-160130 Preferentially Inhibits the KV11.1B Isoform and Produces Antileukemic Effects without Cardiotoxicity
      Luca Gasparoli, Massimo D’Amico, Marika Masselli, Serena Pillozzi, Rachel Caves, Rawan Khuwaileh, Wolfgang Tiedke, Kenneth Mugridge, Alessandro Pratesi, John S. Mitcheson, Giuseppe Basso, Andrea Becchetti and Annarosa Arcangeli
      Molecular Pharmacology February 2015, 87 (2) 183-196; DOI: https://doi.org/10.1124/mol.114.094920

  15. Motamedi, Massoud

    1. Pharmacological Inhibition and Genetic Knockdown of Exchange Protein Directly Activated by cAMP 1 Reduce Pancreatic Cancer Metastasis In Vivo
      Muayad Almahariq, Celia Chao, Fang C. Mei, Mark R. Hellmich, Igor Patrikeev, Massoud Motamedi and Xiaodong Cheng
      Molecular Pharmacology February 2015, 87 (2) 142-149; DOI: https://doi.org/10.1124/mol.114.095158

  16. Mugridge, Kenneth

    1. New Pyrimido-Indole Compound CD-160130 Preferentially Inhibits the KV11.1B Isoform and Produces Antileukemic Effects without Cardiotoxicity
      Luca Gasparoli, Massimo D’Amico, Marika Masselli, Serena Pillozzi, Rachel Caves, Rawan Khuwaileh, Wolfgang Tiedke, Kenneth Mugridge, Alessandro Pratesi, John S. Mitcheson, Giuseppe Basso, Andrea Becchetti and Annarosa Arcangeli
      Molecular Pharmacology February 2015, 87 (2) 183-196; DOI: https://doi.org/10.1124/mol.114.094920

  17. Müller, Rolf

    1. The Inverse Agonist DG172 Triggers a PPARβ/δ-Independent Myeloid Lineage Shift and Promotes GM-CSF/IL-4-Induced Dendritic Cell Differentiation
      Sonja Lieber, Frithjof Scheer, Florian Finkernagel, Wolfgang Meissner, Gavin Giehl, Cornelia Brendel, Wibke E. Diederich, Sabine Müller-Brüsselbach and Rolf Müller
      Molecular Pharmacology February 2015, 87 (2) 162-173; DOI: https://doi.org/10.1124/mol.114.094672

  18. Müller-Brüsselbach, Sabine

    1. The Inverse Agonist DG172 Triggers a PPARβ/δ-Independent Myeloid Lineage Shift and Promotes GM-CSF/IL-4-Induced Dendritic Cell Differentiation
      Sonja Lieber, Frithjof Scheer, Florian Finkernagel, Wolfgang Meissner, Gavin Giehl, Cornelia Brendel, Wibke E. Diederich, Sabine Müller-Brüsselbach and Rolf Müller
      Molecular Pharmacology February 2015, 87 (2) 162-173; DOI: https://doi.org/10.1124/mol.114.094672

N

  1. Naesens, Lieve

    1. An Integrated Biological Approach to Guide the Development of Metal-Chelating Inhibitors of Influenza Virus PA Endonuclease
      Annelies Stevaert, Salvatore Nurra, Nicolino Pala, Mauro Carcelli, Dominga Rogolino, Caitlin Shepard, Robert A. Domaoal, Baek Kim, Mercedes Alfonso-Prieto, Salvatore A. E. Marras, Mario Sechi and Lieve Naesens
      Molecular Pharmacology February 2015, 87 (2) 323-337; DOI: https://doi.org/10.1124/mol.114.095588

  2. Nahta, Rita

    1. Insulin-Like Growth Factor-1 Receptor Signaling Increases the Invasive Potential of Human Epidermal Growth Factor Receptor 2–Overexpressing Breast Cancer Cells via Src-Focal Adhesion Kinase and Forkhead Box Protein M1
      Eduardo Sanabria-Figueroa, Siobhan M. Donnelly, Kevin C. Foy, Meghan C. Buss, Robert C. Castellino, Elisavet Paplomata, Latonia Taliaferro-Smith, Pravin T.P. Kaumaya and Rita Nahta
      Molecular Pharmacology February 2015, 87 (2) 150-161; DOI: https://doi.org/10.1124/mol.114.095380

  3. Nishida, Teruo

    1. Signaling Mechanism Underlying the Promotion of Keratinocyte Migration by Angiotensin II
      Hiroki Sakai, Kenji Matsuura, Yoshie Tanaka, Takeshi Honda, Teruo Nishida and Makoto Inui
      Molecular Pharmacology February 2015, 87 (2) 277-285; DOI: https://doi.org/10.1124/mol.114.096461

  4. Nuhant, Philippe

    1. Antiproliferation Activity of a Small Molecule Repressor of Liver Receptor Homolog 1
      Cesar A. Corzo, Yelenis Mari, Mi Ra Chang, Tanya Khan, Dana Kuruvilla, Philippe Nuhant, Naresh Kumar, Graham M. West, Derek R. Duckett, William R. Roush and Patrick R. Griffin
      Molecular Pharmacology February 2015, 87 (2) 296-304; DOI: https://doi.org/10.1124/mol.114.095554

  5. Nurra, Salvatore

    1. An Integrated Biological Approach to Guide the Development of Metal-Chelating Inhibitors of Influenza Virus PA Endonuclease
      Annelies Stevaert, Salvatore Nurra, Nicolino Pala, Mauro Carcelli, Dominga Rogolino, Caitlin Shepard, Robert A. Domaoal, Baek Kim, Mercedes Alfonso-Prieto, Salvatore A. E. Marras, Mario Sechi and Lieve Naesens
      Molecular Pharmacology February 2015, 87 (2) 323-337; DOI: https://doi.org/10.1124/mol.114.095588

O

  1. Ohdo, Shigehiro

    1. Modulation of Peroxisome Proliferator-Activated Receptor-α Activity by Bile Acids Causes Circadian Changes in the Intestinal Expression of Octn1/Slc22a4 in Mice
      Erika Wada, Satoru Koyanagi, Naoki Kusunose, Takahiro Akamine, Hiroaki Masui, Hana Hashimoto, Naoya Matsunaga and Shigehiro Ohdo
      Molecular Pharmacology February 2015, 87 (2) 314-322; DOI: https://doi.org/10.1124/mol.114.094979

  2. Oliván-Viguera, Aida

    1. A Novel Pan-Negative-Gating Modulator of KCa2/3 Channels, Fluoro-Di-Benzoate, RA-2, Inhibits Endothelium-Derived Hyperpolarization–Type Relaxation in Coronary Artery and Produces Bradycardia In Vivo
      Aida Oliván-Viguera, Marta Sofía Valero, Nicole Coleman, Brandon M. Brown, Celia Laría, María Divina Murillo, José A. Gálvez, María D. Díaz-de-Villegas, Heike Wulff, Ramón Badorrey and Ralf Köhler
      Molecular Pharmacology February 2015, 87 (2) 338-348; DOI: https://doi.org/10.1124/mol.114.095745

  3. Olszewska, Teresa

    1. (4-(Bis(4-Fluorophenyl)Methyl)Piperazin-1-yl)(Cyclohexyl)Methanone Hydrochloride (LDK1229): A New Cannabinoid CB1 Receptor Inverse Agonist from the Class of Benzhydryl Piperazine Analogs
      Mariam M. Mahmoud, Teresa Olszewska, Hui Liu, Derek M. Shore, Dow P. Hurst, Patricia H. Reggio, Dai Lu and Debra A. Kendall
      Molecular Pharmacology February 2015, 87 (2) 197-206; DOI: https://doi.org/10.1124/mol.114.095471

  4. Ortiz Zacarías, Natalia V.

    1. Sodium Ion Binding Pocket Mutations and Adenosine A2A Receptor Function
      Arnault Massink, Hugo Gutiérrez-de-Terán, Eelke B. Lenselink, Natalia V. Ortiz Zacarías, Lizi Xia, Laura H. Heitman, Vsevolod Katritch, Raymond C. Stevens and Adriaan P. IJzerman
      Molecular Pharmacology February 2015, 87 (2) 305-313; DOI: https://doi.org/10.1124/mol.114.095737

P

  1. Pala, Nicolino

    1. An Integrated Biological Approach to Guide the Development of Metal-Chelating Inhibitors of Influenza Virus PA Endonuclease
      Annelies Stevaert, Salvatore Nurra, Nicolino Pala, Mauro Carcelli, Dominga Rogolino, Caitlin Shepard, Robert A. Domaoal, Baek Kim, Mercedes Alfonso-Prieto, Salvatore A. E. Marras, Mario Sechi and Lieve Naesens
      Molecular Pharmacology February 2015, 87 (2) 323-337; DOI: https://doi.org/10.1124/mol.114.095588

  2. Paplomata, Elisavet

    1. Insulin-Like Growth Factor-1 Receptor Signaling Increases the Invasive Potential of Human Epidermal Growth Factor Receptor 2–Overexpressing Breast Cancer Cells via Src-Focal Adhesion Kinase and Forkhead Box Protein M1
      Eduardo Sanabria-Figueroa, Siobhan M. Donnelly, Kevin C. Foy, Meghan C. Buss, Robert C. Castellino, Elisavet Paplomata, Latonia Taliaferro-Smith, Pravin T.P. Kaumaya and Rita Nahta
      Molecular Pharmacology February 2015, 87 (2) 150-161; DOI: https://doi.org/10.1124/mol.114.095380

  3. Patrikeev, Igor

    1. Pharmacological Inhibition and Genetic Knockdown of Exchange Protein Directly Activated by cAMP 1 Reduce Pancreatic Cancer Metastasis In Vivo
      Muayad Almahariq, Celia Chao, Fang C. Mei, Mark R. Hellmich, Igor Patrikeev, Massoud Motamedi and Xiaodong Cheng
      Molecular Pharmacology February 2015, 87 (2) 142-149; DOI: https://doi.org/10.1124/mol.114.095158

  4. Phipps, Elizabeth A.

    1. A Peptide Mimicking a Region in Proliferating Cell Nuclear Antigen Specific to Key Protein Interactions Is Cytotoxic to Breast Cancer
      Shanna J. Smith, Long Gu, Elizabeth A. Phipps, Lacey E. Dobrolecki, Karla S. Mabrey, Pattie Gulley, Kelsey L. Dillehay, Zhongyun Dong, Gregg B. Fields, Yun-Ru Chen, David Ann, Robert J. Hickey and Linda H. Malkas
      Molecular Pharmacology February 2015, 87 (2) 263-276; DOI: https://doi.org/10.1124/mol.114.093211

  5. Pillozzi, Serena

    1. New Pyrimido-Indole Compound CD-160130 Preferentially Inhibits the KV11.1B Isoform and Produces Antileukemic Effects without Cardiotoxicity
      Luca Gasparoli, Massimo D’Amico, Marika Masselli, Serena Pillozzi, Rachel Caves, Rawan Khuwaileh, Wolfgang Tiedke, Kenneth Mugridge, Alessandro Pratesi, John S. Mitcheson, Giuseppe Basso, Andrea Becchetti and Annarosa Arcangeli
      Molecular Pharmacology February 2015, 87 (2) 183-196; DOI: https://doi.org/10.1124/mol.114.094920

  6. Pratesi, Alessandro

    1. New Pyrimido-Indole Compound CD-160130 Preferentially Inhibits the KV11.1B Isoform and Produces Antileukemic Effects without Cardiotoxicity
      Luca Gasparoli, Massimo D’Amico, Marika Masselli, Serena Pillozzi, Rachel Caves, Rawan Khuwaileh, Wolfgang Tiedke, Kenneth Mugridge, Alessandro Pratesi, John S. Mitcheson, Giuseppe Basso, Andrea Becchetti and Annarosa Arcangeli
      Molecular Pharmacology February 2015, 87 (2) 183-196; DOI: https://doi.org/10.1124/mol.114.094920

Q

  1. Quinn, Bridget A.

    1. Reversing Translational Suppression and Induction of Toxicity in Pancreatic Cancer Cells Using a Chemoprevention Gene Therapy Approach
      Siddik Sarkar, Bridget A. Quinn, Xuening Shen, Paul Dent, Swadesh K. Das, Luni Emdad, Devanand Sarkar and Paul B. Fisher
      Molecular Pharmacology February 2015, 87 (2) 286-295; DOI: https://doi.org/10.1124/mol.114.094375

R

  1. Reggio, Patricia H.

    1. (4-(Bis(4-Fluorophenyl)Methyl)Piperazin-1-yl)(Cyclohexyl)Methanone Hydrochloride (LDK1229): A New Cannabinoid CB1 Receptor Inverse Agonist from the Class of Benzhydryl Piperazine Analogs
      Mariam M. Mahmoud, Teresa Olszewska, Hui Liu, Derek M. Shore, Dow P. Hurst, Patricia H. Reggio, Dai Lu and Debra A. Kendall
      Molecular Pharmacology February 2015, 87 (2) 197-206; DOI: https://doi.org/10.1124/mol.114.095471

  2. Rogolino, Dominga

    1. An Integrated Biological Approach to Guide the Development of Metal-Chelating Inhibitors of Influenza Virus PA Endonuclease
      Annelies Stevaert, Salvatore Nurra, Nicolino Pala, Mauro Carcelli, Dominga Rogolino, Caitlin Shepard, Robert A. Domaoal, Baek Kim, Mercedes Alfonso-Prieto, Salvatore A. E. Marras, Mario Sechi and Lieve Naesens
      Molecular Pharmacology February 2015, 87 (2) 323-337; DOI: https://doi.org/10.1124/mol.114.095588

  3. Roobrouck, A.

    1. Potent and Efficacious Inhibition of CXCR2 Signaling by Biparatopic Nanobodies Combining Two Distinct Modes of Action
      M. E. Bradley, B. Dombrecht, J. Manini, J. Willis, D. Vlerick, S. De Taeye, K. Van den Heede, A. Roobrouck, E. Grot, T. C. Kent, T. Laeremans, S. Steffensen, G. Van Heeke, Z. Brown, S. J. Charlton and K. D. Cromie
      Molecular Pharmacology February 2015, 87 (2) 251-262; DOI: https://doi.org/10.1124/mol.114.094821

  4. Roush, William R.

    1. Antiproliferation Activity of a Small Molecule Repressor of Liver Receptor Homolog 1
      Cesar A. Corzo, Yelenis Mari, Mi Ra Chang, Tanya Khan, Dana Kuruvilla, Philippe Nuhant, Naresh Kumar, Graham M. West, Derek R. Duckett, William R. Roush and Patrick R. Griffin
      Molecular Pharmacology February 2015, 87 (2) 296-304; DOI: https://doi.org/10.1124/mol.114.095554

S

  1. Sakai, Hiroki

    1. Signaling Mechanism Underlying the Promotion of Keratinocyte Migration by Angiotensin II
      Hiroki Sakai, Kenji Matsuura, Yoshie Tanaka, Takeshi Honda, Teruo Nishida and Makoto Inui
      Molecular Pharmacology February 2015, 87 (2) 277-285; DOI: https://doi.org/10.1124/mol.114.096461

  2. Sanabria-Figueroa, Eduardo

    1. Insulin-Like Growth Factor-1 Receptor Signaling Increases the Invasive Potential of Human Epidermal Growth Factor Receptor 2–Overexpressing Breast Cancer Cells via Src-Focal Adhesion Kinase and Forkhead Box Protein M1
      Eduardo Sanabria-Figueroa, Siobhan M. Donnelly, Kevin C. Foy, Meghan C. Buss, Robert C. Castellino, Elisavet Paplomata, Latonia Taliaferro-Smith, Pravin T.P. Kaumaya and Rita Nahta
      Molecular Pharmacology February 2015, 87 (2) 150-161; DOI: https://doi.org/10.1124/mol.114.095380

  3. Sarkar, Devanand

    1. Reversing Translational Suppression and Induction of Toxicity in Pancreatic Cancer Cells Using a Chemoprevention Gene Therapy Approach
      Siddik Sarkar, Bridget A. Quinn, Xuening Shen, Paul Dent, Swadesh K. Das, Luni Emdad, Devanand Sarkar and Paul B. Fisher
      Molecular Pharmacology February 2015, 87 (2) 286-295; DOI: https://doi.org/10.1124/mol.114.094375

  4. Sarkar, Siddik

    1. Reversing Translational Suppression and Induction of Toxicity in Pancreatic Cancer Cells Using a Chemoprevention Gene Therapy Approach
      Siddik Sarkar, Bridget A. Quinn, Xuening Shen, Paul Dent, Swadesh K. Das, Luni Emdad, Devanand Sarkar and Paul B. Fisher
      Molecular Pharmacology February 2015, 87 (2) 286-295; DOI: https://doi.org/10.1124/mol.114.094375

  5. Scheer, Frithjof

    1. The Inverse Agonist DG172 Triggers a PPARβ/δ-Independent Myeloid Lineage Shift and Promotes GM-CSF/IL-4-Induced Dendritic Cell Differentiation
      Sonja Lieber, Frithjof Scheer, Florian Finkernagel, Wolfgang Meissner, Gavin Giehl, Cornelia Brendel, Wibke E. Diederich, Sabine Müller-Brüsselbach and Rolf Müller
      Molecular Pharmacology February 2015, 87 (2) 162-173; DOI: https://doi.org/10.1124/mol.114.094672

  6. Sechi, Mario

    1. An Integrated Biological Approach to Guide the Development of Metal-Chelating Inhibitors of Influenza Virus PA Endonuclease
      Annelies Stevaert, Salvatore Nurra, Nicolino Pala, Mauro Carcelli, Dominga Rogolino, Caitlin Shepard, Robert A. Domaoal, Baek Kim, Mercedes Alfonso-Prieto, Salvatore A. E. Marras, Mario Sechi and Lieve Naesens
      Molecular Pharmacology February 2015, 87 (2) 323-337; DOI: https://doi.org/10.1124/mol.114.095588

  7. Shen, Xuening

    1. Reversing Translational Suppression and Induction of Toxicity in Pancreatic Cancer Cells Using a Chemoprevention Gene Therapy Approach
      Siddik Sarkar, Bridget A. Quinn, Xuening Shen, Paul Dent, Swadesh K. Das, Luni Emdad, Devanand Sarkar and Paul B. Fisher
      Molecular Pharmacology February 2015, 87 (2) 286-295; DOI: https://doi.org/10.1124/mol.114.094375

  8. Shepard, Caitlin

    1. An Integrated Biological Approach to Guide the Development of Metal-Chelating Inhibitors of Influenza Virus PA Endonuclease
      Annelies Stevaert, Salvatore Nurra, Nicolino Pala, Mauro Carcelli, Dominga Rogolino, Caitlin Shepard, Robert A. Domaoal, Baek Kim, Mercedes Alfonso-Prieto, Salvatore A. E. Marras, Mario Sechi and Lieve Naesens
      Molecular Pharmacology February 2015, 87 (2) 323-337; DOI: https://doi.org/10.1124/mol.114.095588

  9. Shore, Derek M.

    1. (4-(Bis(4-Fluorophenyl)Methyl)Piperazin-1-yl)(Cyclohexyl)Methanone Hydrochloride (LDK1229): A New Cannabinoid CB1 Receptor Inverse Agonist from the Class of Benzhydryl Piperazine Analogs
      Mariam M. Mahmoud, Teresa Olszewska, Hui Liu, Derek M. Shore, Dow P. Hurst, Patricia H. Reggio, Dai Lu and Debra A. Kendall
      Molecular Pharmacology February 2015, 87 (2) 197-206; DOI: https://doi.org/10.1124/mol.114.095471

  10. Slesinger, Paul A.

    1. Novel Mechanism of Voltage-Gated N-type (Cav2.2) Calcium Channel Inhibition Revealed through α-Conotoxin Vc1.1 Activation of the GABAB Receptor
      Thuan G. Huynh, Hartmut Cuny, Paul A. Slesinger and David J. Adams
      Molecular Pharmacology February 2015, 87 (2) 240-250; DOI: https://doi.org/10.1124/mol.114.096156

  11. Smith, Shanna J.

    1. A Peptide Mimicking a Region in Proliferating Cell Nuclear Antigen Specific to Key Protein Interactions Is Cytotoxic to Breast Cancer
      Shanna J. Smith, Long Gu, Elizabeth A. Phipps, Lacey E. Dobrolecki, Karla S. Mabrey, Pattie Gulley, Kelsey L. Dillehay, Zhongyun Dong, Gregg B. Fields, Yun-Ru Chen, David Ann, Robert J. Hickey and Linda H. Malkas
      Molecular Pharmacology February 2015, 87 (2) 263-276; DOI: https://doi.org/10.1124/mol.114.093211

  12. Steffensen, S.

    1. Potent and Efficacious Inhibition of CXCR2 Signaling by Biparatopic Nanobodies Combining Two Distinct Modes of Action
      M. E. Bradley, B. Dombrecht, J. Manini, J. Willis, D. Vlerick, S. De Taeye, K. Van den Heede, A. Roobrouck, E. Grot, T. C. Kent, T. Laeremans, S. Steffensen, G. Van Heeke, Z. Brown, S. J. Charlton and K. D. Cromie
      Molecular Pharmacology February 2015, 87 (2) 251-262; DOI: https://doi.org/10.1124/mol.114.094821

  13. Stevaert, Annelies

    1. An Integrated Biological Approach to Guide the Development of Metal-Chelating Inhibitors of Influenza Virus PA Endonuclease
      Annelies Stevaert, Salvatore Nurra, Nicolino Pala, Mauro Carcelli, Dominga Rogolino, Caitlin Shepard, Robert A. Domaoal, Baek Kim, Mercedes Alfonso-Prieto, Salvatore A. E. Marras, Mario Sechi and Lieve Naesens
      Molecular Pharmacology February 2015, 87 (2) 323-337; DOI: https://doi.org/10.1124/mol.114.095588

  14. Stevens, Raymond C.

    1. Sodium Ion Binding Pocket Mutations and Adenosine A2A Receptor Function
      Arnault Massink, Hugo Gutiérrez-de-Terán, Eelke B. Lenselink, Natalia V. Ortiz Zacarías, Lizi Xia, Laura H. Heitman, Vsevolod Katritch, Raymond C. Stevens and Adriaan P. IJzerman
      Molecular Pharmacology February 2015, 87 (2) 305-313; DOI: https://doi.org/10.1124/mol.114.095737

T

  1. Taliaferro-Smith, Latonia

    1. Insulin-Like Growth Factor-1 Receptor Signaling Increases the Invasive Potential of Human Epidermal Growth Factor Receptor 2–Overexpressing Breast Cancer Cells via Src-Focal Adhesion Kinase and Forkhead Box Protein M1
      Eduardo Sanabria-Figueroa, Siobhan M. Donnelly, Kevin C. Foy, Meghan C. Buss, Robert C. Castellino, Elisavet Paplomata, Latonia Taliaferro-Smith, Pravin T.P. Kaumaya and Rita Nahta
      Molecular Pharmacology February 2015, 87 (2) 150-161; DOI: https://doi.org/10.1124/mol.114.095380

  2. Tanaka, Yoshie

    1. Signaling Mechanism Underlying the Promotion of Keratinocyte Migration by Angiotensin II
      Hiroki Sakai, Kenji Matsuura, Yoshie Tanaka, Takeshi Honda, Teruo Nishida and Makoto Inui
      Molecular Pharmacology February 2015, 87 (2) 277-285; DOI: https://doi.org/10.1124/mol.114.096461

  3. Tiedke, Wolfgang

    1. New Pyrimido-Indole Compound CD-160130 Preferentially Inhibits the KV11.1B Isoform and Produces Antileukemic Effects without Cardiotoxicity
      Luca Gasparoli, Massimo D’Amico, Marika Masselli, Serena Pillozzi, Rachel Caves, Rawan Khuwaileh, Wolfgang Tiedke, Kenneth Mugridge, Alessandro Pratesi, John S. Mitcheson, Giuseppe Basso, Andrea Becchetti and Annarosa Arcangeli
      Molecular Pharmacology February 2015, 87 (2) 183-196; DOI: https://doi.org/10.1124/mol.114.094920

  4. Tobin, Andrew B.

    1. Engineered Hyperphosphorylation of the β2-Adrenoceptor Prolongs Arrestin-3 Binding and Induces Arrestin Internalization
      Diana Zindel, Adrian J. Butcher, Suleiman Al-Sabah, Peter Lanzerstorfer, Julian Weghuber, Andrew B. Tobin, Moritz Bünemann and Cornelius Krasel
      Molecular Pharmacology February 2015, 87 (2) 349-362; DOI: https://doi.org/10.1124/mol.114.095422

  5. Tsai, Keng-Chang

    1. Phage Display–Mediated Discovery of Novel Tyrosinase-Targeting Tetrapeptide Inhibitors Reveals the Significance of N-Terminal Preference of Cysteine Residues and Their Functional Sulfur Atom
      Yu-Ching Lee, Nai-Wan Hsiao, Tien-Sheng Tseng, Wang-Chuan Chen, Hui-Hsiung Lin, Sy-Jye Leu, Ei-Wen Yang and Keng-Chang Tsai
      Molecular Pharmacology February 2015, 87 (2) 218-230; DOI: https://doi.org/10.1124/mol.114.094185

  6. Tseng, Tien-Sheng

    1. Phage Display–Mediated Discovery of Novel Tyrosinase-Targeting Tetrapeptide Inhibitors Reveals the Significance of N-Terminal Preference of Cysteine Residues and Their Functional Sulfur Atom
      Yu-Ching Lee, Nai-Wan Hsiao, Tien-Sheng Tseng, Wang-Chuan Chen, Hui-Hsiung Lin, Sy-Jye Leu, Ei-Wen Yang and Keng-Chang Tsai
      Molecular Pharmacology February 2015, 87 (2) 218-230; DOI: https://doi.org/10.1124/mol.114.094185

V

  1. Valero, Marta Sofía

    1. A Novel Pan-Negative-Gating Modulator of KCa2/3 Channels, Fluoro-Di-Benzoate, RA-2, Inhibits Endothelium-Derived Hyperpolarization–Type Relaxation in Coronary Artery and Produces Bradycardia In Vivo
      Aida Oliván-Viguera, Marta Sofía Valero, Nicole Coleman, Brandon M. Brown, Celia Laría, María Divina Murillo, José A. Gálvez, María D. Díaz-de-Villegas, Heike Wulff, Ramón Badorrey and Ralf Köhler
      Molecular Pharmacology February 2015, 87 (2) 338-348; DOI: https://doi.org/10.1124/mol.114.095745

  2. Van den Heede, K.

    1. Potent and Efficacious Inhibition of CXCR2 Signaling by Biparatopic Nanobodies Combining Two Distinct Modes of Action
      M. E. Bradley, B. Dombrecht, J. Manini, J. Willis, D. Vlerick, S. De Taeye, K. Van den Heede, A. Roobrouck, E. Grot, T. C. Kent, T. Laeremans, S. Steffensen, G. Van Heeke, Z. Brown, S. J. Charlton and K. D. Cromie
      Molecular Pharmacology February 2015, 87 (2) 251-262; DOI: https://doi.org/10.1124/mol.114.094821

  3. Van Heeke, G.

    1. Potent and Efficacious Inhibition of CXCR2 Signaling by Biparatopic Nanobodies Combining Two Distinct Modes of Action
      M. E. Bradley, B. Dombrecht, J. Manini, J. Willis, D. Vlerick, S. De Taeye, K. Van den Heede, A. Roobrouck, E. Grot, T. C. Kent, T. Laeremans, S. Steffensen, G. Van Heeke, Z. Brown, S. J. Charlton and K. D. Cromie
      Molecular Pharmacology February 2015, 87 (2) 251-262; DOI: https://doi.org/10.1124/mol.114.094821

  4. Vlerick, D.

    1. Potent and Efficacious Inhibition of CXCR2 Signaling by Biparatopic Nanobodies Combining Two Distinct Modes of Action
      M. E. Bradley, B. Dombrecht, J. Manini, J. Willis, D. Vlerick, S. De Taeye, K. Van den Heede, A. Roobrouck, E. Grot, T. C. Kent, T. Laeremans, S. Steffensen, G. Van Heeke, Z. Brown, S. J. Charlton and K. D. Cromie
      Molecular Pharmacology February 2015, 87 (2) 251-262; DOI: https://doi.org/10.1124/mol.114.094821

W

  1. Wada, Erika

    1. Modulation of Peroxisome Proliferator-Activated Receptor-α Activity by Bile Acids Causes Circadian Changes in the Intestinal Expression of Octn1/Slc22a4 in Mice
      Erika Wada, Satoru Koyanagi, Naoki Kusunose, Takahiro Akamine, Hiroaki Masui, Hana Hashimoto, Naoya Matsunaga and Shigehiro Ohdo
      Molecular Pharmacology February 2015, 87 (2) 314-322; DOI: https://doi.org/10.1124/mol.114.094979

  2. Weghuber, Julian

    1. Engineered Hyperphosphorylation of the β2-Adrenoceptor Prolongs Arrestin-3 Binding and Induces Arrestin Internalization
      Diana Zindel, Adrian J. Butcher, Suleiman Al-Sabah, Peter Lanzerstorfer, Julian Weghuber, Andrew B. Tobin, Moritz Bünemann and Cornelius Krasel
      Molecular Pharmacology February 2015, 87 (2) 349-362; DOI: https://doi.org/10.1124/mol.114.095422

  3. West, Graham M.

    1. Antiproliferation Activity of a Small Molecule Repressor of Liver Receptor Homolog 1
      Cesar A. Corzo, Yelenis Mari, Mi Ra Chang, Tanya Khan, Dana Kuruvilla, Philippe Nuhant, Naresh Kumar, Graham M. West, Derek R. Duckett, William R. Roush and Patrick R. Griffin
      Molecular Pharmacology February 2015, 87 (2) 296-304; DOI: https://doi.org/10.1124/mol.114.095554

  4. Willis, J.

    1. Potent and Efficacious Inhibition of CXCR2 Signaling by Biparatopic Nanobodies Combining Two Distinct Modes of Action
      M. E. Bradley, B. Dombrecht, J. Manini, J. Willis, D. Vlerick, S. De Taeye, K. Van den Heede, A. Roobrouck, E. Grot, T. C. Kent, T. Laeremans, S. Steffensen, G. Van Heeke, Z. Brown, S. J. Charlton and K. D. Cromie
      Molecular Pharmacology February 2015, 87 (2) 251-262; DOI: https://doi.org/10.1124/mol.114.094821

  5. Wulff, Heike

    1. A Novel Pan-Negative-Gating Modulator of KCa2/3 Channels, Fluoro-Di-Benzoate, RA-2, Inhibits Endothelium-Derived Hyperpolarization–Type Relaxation in Coronary Artery and Produces Bradycardia In Vivo
      Aida Oliván-Viguera, Marta Sofía Valero, Nicole Coleman, Brandon M. Brown, Celia Laría, María Divina Murillo, José A. Gálvez, María D. Díaz-de-Villegas, Heike Wulff, Ramón Badorrey and Ralf Köhler
      Molecular Pharmacology February 2015, 87 (2) 338-348; DOI: https://doi.org/10.1124/mol.114.095745

X

  1. Xia, Lizi

    1. Sodium Ion Binding Pocket Mutations and Adenosine A2A Receptor Function
      Arnault Massink, Hugo Gutiérrez-de-Terán, Eelke B. Lenselink, Natalia V. Ortiz Zacarías, Lizi Xia, Laura H. Heitman, Vsevolod Katritch, Raymond C. Stevens and Adriaan P. IJzerman
      Molecular Pharmacology February 2015, 87 (2) 305-313; DOI: https://doi.org/10.1124/mol.114.095737

  2. Xu, Kaiping

    1. Reporting Sodium Channel Activity Using Calcium Flux: Pharmacological Promiscuity of Cardiac Nav1.5
      Hongkang Zhang, Beiyan Zou, Fang Du, Kaiping Xu and Min Li
      Molecular Pharmacology February 2015, 87 (2) 207-217; DOI: https://doi.org/10.1124/mol.114.094789

Y

  1. Yang, Ei-Wen

    1. Phage Display–Mediated Discovery of Novel Tyrosinase-Targeting Tetrapeptide Inhibitors Reveals the Significance of N-Terminal Preference of Cysteine Residues and Their Functional Sulfur Atom
      Yu-Ching Lee, Nai-Wan Hsiao, Tien-Sheng Tseng, Wang-Chuan Chen, Hui-Hsiung Lin, Sy-Jye Leu, Ei-Wen Yang and Keng-Chang Tsai
      Molecular Pharmacology February 2015, 87 (2) 218-230; DOI: https://doi.org/10.1124/mol.114.094185

Z

  1. Zhang, Hongkang

    1. Reporting Sodium Channel Activity Using Calcium Flux: Pharmacological Promiscuity of Cardiac Nav1.5
      Hongkang Zhang, Beiyan Zou, Fang Du, Kaiping Xu and Min Li
      Molecular Pharmacology February 2015, 87 (2) 207-217; DOI: https://doi.org/10.1124/mol.114.094789

  2. Zindel, Diana

    1. Engineered Hyperphosphorylation of the β2-Adrenoceptor Prolongs Arrestin-3 Binding and Induces Arrestin Internalization
      Diana Zindel, Adrian J. Butcher, Suleiman Al-Sabah, Peter Lanzerstorfer, Julian Weghuber, Andrew B. Tobin, Moritz Bünemann and Cornelius Krasel
      Molecular Pharmacology February 2015, 87 (2) 349-362; DOI: https://doi.org/10.1124/mol.114.095422

  3. Zou, Beiyan

    1. Reporting Sodium Channel Activity Using Calcium Flux: Pharmacological Promiscuity of Cardiac Nav1.5
      Hongkang Zhang, Beiyan Zou, Fang Du, Kaiping Xu and Min Li
      Molecular Pharmacology February 2015, 87 (2) 207-217; DOI: https://doi.org/10.1124/mol.114.094789
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