Research ArticleArticle
Insulin-Like Growth Factor-1 Receptor Signaling Increases the Invasive Potential of Human Epidermal Growth Factor Receptor 2–Overexpressing Breast Cancer Cells via Src-Focal Adhesion Kinase and Forkhead Box Protein M1
Eduardo Sanabria-Figueroa, Siobhan M. Donnelly, Kevin C. Foy, Meghan C. Buss, Robert C. Castellino, Elisavet Paplomata, Latonia Taliaferro-Smith, Pravin T.P. Kaumaya and Rita Nahta
Molecular Pharmacology February 2015, 87 (2) 150-161; DOI: https://doi.org/10.1124/mol.114.095380
Eduardo Sanabria-Figueroa
Departments of Pharmacology (E.S.-F., S.M.D., R.N.) and Hematology and Medical Oncology (E.P., L.T.-S., R.N.), School of Medicine, and Molecular and Systems Pharmacology Program, Graduate Division of Biological and Biomedical Sciences (E.S.-F., R.N.), and Winship Cancer Institute (R.C.C., E.P., L.T.-S., R.N.), Emory University, Atlanta, Georgia; Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta, Atlanta, Georgia (M.C.B., R.C.C.); and Departments of Obstetrics and Gynecology and Microbiology, James Cancer Hospital, Solove Research Institute and Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio (K.C.F., P.T.P.K.)
Siobhan M. Donnelly
Departments of Pharmacology (E.S.-F., S.M.D., R.N.) and Hematology and Medical Oncology (E.P., L.T.-S., R.N.), School of Medicine, and Molecular and Systems Pharmacology Program, Graduate Division of Biological and Biomedical Sciences (E.S.-F., R.N.), and Winship Cancer Institute (R.C.C., E.P., L.T.-S., R.N.), Emory University, Atlanta, Georgia; Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta, Atlanta, Georgia (M.C.B., R.C.C.); and Departments of Obstetrics and Gynecology and Microbiology, James Cancer Hospital, Solove Research Institute and Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio (K.C.F., P.T.P.K.)
Kevin C. Foy
Departments of Pharmacology (E.S.-F., S.M.D., R.N.) and Hematology and Medical Oncology (E.P., L.T.-S., R.N.), School of Medicine, and Molecular and Systems Pharmacology Program, Graduate Division of Biological and Biomedical Sciences (E.S.-F., R.N.), and Winship Cancer Institute (R.C.C., E.P., L.T.-S., R.N.), Emory University, Atlanta, Georgia; Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta, Atlanta, Georgia (M.C.B., R.C.C.); and Departments of Obstetrics and Gynecology and Microbiology, James Cancer Hospital, Solove Research Institute and Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio (K.C.F., P.T.P.K.)
Meghan C. Buss
Departments of Pharmacology (E.S.-F., S.M.D., R.N.) and Hematology and Medical Oncology (E.P., L.T.-S., R.N.), School of Medicine, and Molecular and Systems Pharmacology Program, Graduate Division of Biological and Biomedical Sciences (E.S.-F., R.N.), and Winship Cancer Institute (R.C.C., E.P., L.T.-S., R.N.), Emory University, Atlanta, Georgia; Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta, Atlanta, Georgia (M.C.B., R.C.C.); and Departments of Obstetrics and Gynecology and Microbiology, James Cancer Hospital, Solove Research Institute and Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio (K.C.F., P.T.P.K.)
Robert C. Castellino
Departments of Pharmacology (E.S.-F., S.M.D., R.N.) and Hematology and Medical Oncology (E.P., L.T.-S., R.N.), School of Medicine, and Molecular and Systems Pharmacology Program, Graduate Division of Biological and Biomedical Sciences (E.S.-F., R.N.), and Winship Cancer Institute (R.C.C., E.P., L.T.-S., R.N.), Emory University, Atlanta, Georgia; Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta, Atlanta, Georgia (M.C.B., R.C.C.); and Departments of Obstetrics and Gynecology and Microbiology, James Cancer Hospital, Solove Research Institute and Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio (K.C.F., P.T.P.K.)
Elisavet Paplomata
Departments of Pharmacology (E.S.-F., S.M.D., R.N.) and Hematology and Medical Oncology (E.P., L.T.-S., R.N.), School of Medicine, and Molecular and Systems Pharmacology Program, Graduate Division of Biological and Biomedical Sciences (E.S.-F., R.N.), and Winship Cancer Institute (R.C.C., E.P., L.T.-S., R.N.), Emory University, Atlanta, Georgia; Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta, Atlanta, Georgia (M.C.B., R.C.C.); and Departments of Obstetrics and Gynecology and Microbiology, James Cancer Hospital, Solove Research Institute and Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio (K.C.F., P.T.P.K.)
Latonia Taliaferro-Smith
Departments of Pharmacology (E.S.-F., S.M.D., R.N.) and Hematology and Medical Oncology (E.P., L.T.-S., R.N.), School of Medicine, and Molecular and Systems Pharmacology Program, Graduate Division of Biological and Biomedical Sciences (E.S.-F., R.N.), and Winship Cancer Institute (R.C.C., E.P., L.T.-S., R.N.), Emory University, Atlanta, Georgia; Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta, Atlanta, Georgia (M.C.B., R.C.C.); and Departments of Obstetrics and Gynecology and Microbiology, James Cancer Hospital, Solove Research Institute and Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio (K.C.F., P.T.P.K.)
Pravin T.P. Kaumaya
Departments of Pharmacology (E.S.-F., S.M.D., R.N.) and Hematology and Medical Oncology (E.P., L.T.-S., R.N.), School of Medicine, and Molecular and Systems Pharmacology Program, Graduate Division of Biological and Biomedical Sciences (E.S.-F., R.N.), and Winship Cancer Institute (R.C.C., E.P., L.T.-S., R.N.), Emory University, Atlanta, Georgia; Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta, Atlanta, Georgia (M.C.B., R.C.C.); and Departments of Obstetrics and Gynecology and Microbiology, James Cancer Hospital, Solove Research Institute and Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio (K.C.F., P.T.P.K.)
Rita Nahta
Departments of Pharmacology (E.S.-F., S.M.D., R.N.) and Hematology and Medical Oncology (E.P., L.T.-S., R.N.), School of Medicine, and Molecular and Systems Pharmacology Program, Graduate Division of Biological and Biomedical Sciences (E.S.-F., R.N.), and Winship Cancer Institute (R.C.C., E.P., L.T.-S., R.N.), Emory University, Atlanta, Georgia; Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta, Atlanta, Georgia (M.C.B., R.C.C.); and Departments of Obstetrics and Gynecology and Microbiology, James Cancer Hospital, Solove Research Institute and Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio (K.C.F., P.T.P.K.)
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IGF-1R–Mediated Invasion in HER2-Positive Cancer Cells
Eduardo Sanabria-Figueroa, Siobhan M. Donnelly, Kevin C. Foy, Meghan C. Buss, Robert C. Castellino, Elisavet Paplomata, Latonia Taliaferro-Smith, Pravin T.P. Kaumaya and Rita Nahta
Molecular Pharmacology February 1, 2015, 87 (2) 150-161; DOI: https://doi.org/10.1124/mol.114.095380
Research ArticleArticle
IGF-1R–Mediated Invasion in HER2-Positive Cancer Cells
Eduardo Sanabria-Figueroa, Siobhan M. Donnelly, Kevin C. Foy, Meghan C. Buss, Robert C. Castellino, Elisavet Paplomata, Latonia Taliaferro-Smith, Pravin T.P. Kaumaya and Rita Nahta
Molecular Pharmacology February 1, 2015, 87 (2) 150-161; DOI: https://doi.org/10.1124/mol.114.095380
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