Research ArticleArticle
Yet Another Function of p53—The Switch That Determines Whether Radiation-Induced Autophagy Will Be Cytoprotective or Nonprotective: Implications for Autophagy Inhibition as a Therapeutic Strategy
Shweta Chakradeo, Khushboo Sharma, Aisha Alhaddad, Duaa Bakhshwin, Ngoc Le, Hisashi Harada, Wataru Nakajima, W. Andrew Yeudall, Suzy V. Torti, Frank M. Torti and David A. Gewirtz
Molecular Pharmacology May 2015, 87 (5) 803-814; DOI: https://doi.org/10.1124/mol.114.095273
Shweta Chakradeo
Departments of Medicine and Pharmacology and Toxicology, Massey Cancer Center (S.C., K.S., A.A., D.B., N.L., D.A.G.), and Department of Oral and Craniofacial Molecular Biology, School of Dentistry (H.H., W.N., W.A.Y.), Virginia Commonwealth University, Richmond, Virginia; and Departments of Molecular Biology and Biophysics (S.V.T.) and Medicine (F.M.T.), University of Connecticut Health Sciences, Farmington, Connecticut
Khushboo Sharma
Departments of Medicine and Pharmacology and Toxicology, Massey Cancer Center (S.C., K.S., A.A., D.B., N.L., D.A.G.), and Department of Oral and Craniofacial Molecular Biology, School of Dentistry (H.H., W.N., W.A.Y.), Virginia Commonwealth University, Richmond, Virginia; and Departments of Molecular Biology and Biophysics (S.V.T.) and Medicine (F.M.T.), University of Connecticut Health Sciences, Farmington, Connecticut
Aisha Alhaddad
Departments of Medicine and Pharmacology and Toxicology, Massey Cancer Center (S.C., K.S., A.A., D.B., N.L., D.A.G.), and Department of Oral and Craniofacial Molecular Biology, School of Dentistry (H.H., W.N., W.A.Y.), Virginia Commonwealth University, Richmond, Virginia; and Departments of Molecular Biology and Biophysics (S.V.T.) and Medicine (F.M.T.), University of Connecticut Health Sciences, Farmington, Connecticut
Duaa Bakhshwin
Departments of Medicine and Pharmacology and Toxicology, Massey Cancer Center (S.C., K.S., A.A., D.B., N.L., D.A.G.), and Department of Oral and Craniofacial Molecular Biology, School of Dentistry (H.H., W.N., W.A.Y.), Virginia Commonwealth University, Richmond, Virginia; and Departments of Molecular Biology and Biophysics (S.V.T.) and Medicine (F.M.T.), University of Connecticut Health Sciences, Farmington, Connecticut
Ngoc Le
Departments of Medicine and Pharmacology and Toxicology, Massey Cancer Center (S.C., K.S., A.A., D.B., N.L., D.A.G.), and Department of Oral and Craniofacial Molecular Biology, School of Dentistry (H.H., W.N., W.A.Y.), Virginia Commonwealth University, Richmond, Virginia; and Departments of Molecular Biology and Biophysics (S.V.T.) and Medicine (F.M.T.), University of Connecticut Health Sciences, Farmington, Connecticut
Hisashi Harada
Departments of Medicine and Pharmacology and Toxicology, Massey Cancer Center (S.C., K.S., A.A., D.B., N.L., D.A.G.), and Department of Oral and Craniofacial Molecular Biology, School of Dentistry (H.H., W.N., W.A.Y.), Virginia Commonwealth University, Richmond, Virginia; and Departments of Molecular Biology and Biophysics (S.V.T.) and Medicine (F.M.T.), University of Connecticut Health Sciences, Farmington, Connecticut
Wataru Nakajima
Departments of Medicine and Pharmacology and Toxicology, Massey Cancer Center (S.C., K.S., A.A., D.B., N.L., D.A.G.), and Department of Oral and Craniofacial Molecular Biology, School of Dentistry (H.H., W.N., W.A.Y.), Virginia Commonwealth University, Richmond, Virginia; and Departments of Molecular Biology and Biophysics (S.V.T.) and Medicine (F.M.T.), University of Connecticut Health Sciences, Farmington, Connecticut
W. Andrew Yeudall
Departments of Medicine and Pharmacology and Toxicology, Massey Cancer Center (S.C., K.S., A.A., D.B., N.L., D.A.G.), and Department of Oral and Craniofacial Molecular Biology, School of Dentistry (H.H., W.N., W.A.Y.), Virginia Commonwealth University, Richmond, Virginia; and Departments of Molecular Biology and Biophysics (S.V.T.) and Medicine (F.M.T.), University of Connecticut Health Sciences, Farmington, Connecticut
Suzy V. Torti
Departments of Medicine and Pharmacology and Toxicology, Massey Cancer Center (S.C., K.S., A.A., D.B., N.L., D.A.G.), and Department of Oral and Craniofacial Molecular Biology, School of Dentistry (H.H., W.N., W.A.Y.), Virginia Commonwealth University, Richmond, Virginia; and Departments of Molecular Biology and Biophysics (S.V.T.) and Medicine (F.M.T.), University of Connecticut Health Sciences, Farmington, Connecticut
Frank M. Torti
Departments of Medicine and Pharmacology and Toxicology, Massey Cancer Center (S.C., K.S., A.A., D.B., N.L., D.A.G.), and Department of Oral and Craniofacial Molecular Biology, School of Dentistry (H.H., W.N., W.A.Y.), Virginia Commonwealth University, Richmond, Virginia; and Departments of Molecular Biology and Biophysics (S.V.T.) and Medicine (F.M.T.), University of Connecticut Health Sciences, Farmington, Connecticut
David A. Gewirtz
Departments of Medicine and Pharmacology and Toxicology, Massey Cancer Center (S.C., K.S., A.A., D.B., N.L., D.A.G.), and Department of Oral and Craniofacial Molecular Biology, School of Dentistry (H.H., W.N., W.A.Y.), Virginia Commonwealth University, Richmond, Virginia; and Departments of Molecular Biology and Biophysics (S.V.T.) and Medicine (F.M.T.), University of Connecticut Health Sciences, Farmington, Connecticut

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Research ArticleArticle
p53, Autophagy, and Radiation in Cancer Therapy
Shweta Chakradeo, Khushboo Sharma, Aisha Alhaddad, Duaa Bakhshwin, Ngoc Le, Hisashi Harada, Wataru Nakajima, W. Andrew Yeudall, Suzy V. Torti, Frank M. Torti and David A. Gewirtz
Molecular Pharmacology May 1, 2015, 87 (5) 803-814; DOI: https://doi.org/10.1124/mol.114.095273
Research ArticleArticle
p53, Autophagy, and Radiation in Cancer Therapy
Shweta Chakradeo, Khushboo Sharma, Aisha Alhaddad, Duaa Bakhshwin, Ngoc Le, Hisashi Harada, Wataru Nakajima, W. Andrew Yeudall, Suzy V. Torti, Frank M. Torti and David A. Gewirtz
Molecular Pharmacology May 1, 2015, 87 (5) 803-814; DOI: https://doi.org/10.1124/mol.114.095273
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