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Molecular Pharmacology

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Table of Contents

June 01, 2015; Volume 87,Issue 6

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    G Protein Regulation of Neuronal Calcium Channels: Back to the Future
    Juliane Proft and Norbert Weiss
    Molecular Pharmacology June 2015, 87 (6) 890-906; DOI: https://doi.org/10.1124/mol.114.096008

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    Molecular Determinants of CGS21680 Binding to the Human Adenosine A2A Receptor
    Guillaume Lebon, Patricia C. Edwards, Andrew G. W. Leslie and Christopher G. Tate
    Molecular Pharmacology June 2015, 87 (6) 907-915; DOI: https://doi.org/10.1124/mol.114.097360
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    FTY720 Phosphate Activates Sphingosine-1-Phosphate Receptor 2 and Selectively Couples to Gα12/13/Rho/ROCK to Induce Myofibroblast Contraction
    Katrin Sobel, Lucile Monnier, Katalin Menyhart, Matthias Bolinger, Rolf Studer, Oliver Nayler and John Gatfield
    Molecular Pharmacology June 2015, 87 (6) 916-927; DOI: https://doi.org/10.1124/mol.114.097261
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    Cyclic Adenosine 3′,5′-Monophosphate Elevation and Biological Signaling through a Secretin Family Gs-Coupled G Protein–Coupled Receptor Are Restricted to a Single Adenylate Cyclase Isoform
    Andrew C. Emery, Xiu-Huai Liu, Wenqin Xu, Maribeth V. Eiden and Lee E. Eiden
    Molecular Pharmacology June 2015, 87 (6) 928-935; DOI: https://doi.org/10.1124/mol.115.098087
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    The Molecular Basis of Oligomeric Organization of the Human M3 Muscarinic Acetylcholine Receptor
    María José Varela Liste, Gianluigi Caltabiano, Richard J. Ward, Elisa Alvarez-Curto, Sara Marsango and Graeme Milligan
    Molecular Pharmacology June 2015, 87 (6) 936-953; DOI: https://doi.org/10.1124/mol.114.096925
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    Salmeterol Efficacy and Bias in the Activation and Kinase-Mediated Desensitization of β2-Adrenergic Receptors
    Luis E. Gimenez, Faiza Baameur, Sharat J. Vayttaden and Richard B. Clark
    Molecular Pharmacology June 2015, 87 (6) 954-964; DOI: https://doi.org/10.1124/mol.114.096800
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    Pharmacological NAD-Boosting Strategies Improve Mitochondrial Homeostasis in Human Complex I–Mutant Fibroblasts
    Roberta Felici, Andrea Lapucci, Leonardo Cavone, Sara Pratesi, Rolando Berlinguer-Palmini and Alberto Chiarugi
    Molecular Pharmacology June 2015, 87 (6) 965-971; DOI: https://doi.org/10.1124/mol.114.097204
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    Investigation of the Fate of Type I Angiotensin Receptor after Biased Activation
    Gyöngyi Szakadáti, András D. Tóth, Ilona Oláh, László Sándor Erdélyi, Tamas Balla, Péter Várnai, László Hunyady and András Balla
    Molecular Pharmacology June 2015, 87 (6) 972-981; DOI: https://doi.org/10.1124/mol.114.097030
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    Characterization of Angiotensin II Molecular Determinants Involved in AT1 Receptor Functional Selectivity
    Ivana Domazet, Brian J. Holleran, Alexandra Richard, Camille Vandenberghe, Pierre Lavigne, Emanuel Escher, Richard Leduc and Gaétan Guillemette
    Molecular Pharmacology June 2015, 87 (6) 982-995; DOI: https://doi.org/10.1124/mol.114.097337
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    The Novel Ribonucleotide Reductase Inhibitor COH29 Inhibits DNA Repair In Vitro
    Mei-Chuan Chen, Bingsen Zhou, Keqiang Zhang, Yate-Ching Yuan, Frank Un, Shuya Hu, Chih-Ming Chou, Chun-Han Chen, Jun Wu, Yan Wang, Xiyong Liu, D. Lynne Smith, Hongzhi Li, Zheng Liu, Charles D. Warden, Leila Su, Linda H. Malkas, Young Min Chung, Mickey C.-T. Hu and Yun Yen
    Molecular Pharmacology June 2015, 87 (6) 996-1005; DOI: https://doi.org/10.1124/mol.114.094987
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    Dual Targeting of the Androgen Receptor and Hypoxia-Inducible Factor 1α Pathways Synergistically Inhibits Castration-Resistant Prostate Cancer Cells
    Elena V. Fernandez, Kelie M. Reece, Ariel M. Ley, Sarah M. Troutman, Tristan M. Sissung, Douglas K. Price, Cindy H. Chau and William D. Figg
    Molecular Pharmacology June 2015, 87 (6) 1006-1012; DOI: https://doi.org/10.1124/mol.114.097477
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    Activating and Inhibitory Functions of WNT/β-Catenin in the Induction of Cytochromes P450 by Nuclear Receptors in HepaRG Cells
    Maria Thomas, Christine Bayha, Silvia Vetter, Ute Hofmann, Michael Schwarz, Ulrich M. Zanger and Albert Braeuning
    Molecular Pharmacology June 2015, 87 (6) 1013-1020; DOI: https://doi.org/10.1124/mol.114.097402
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    The Nurr1 Activator 1,1-Bis(3′-Indolyl)-1-(p-Chlorophenyl)Methane Blocks Inflammatory Gene Expression in BV-2 Microglial Cells by Inhibiting Nuclear Factor κB
    Briana R. De Miranda, Katriana A. Popichak, Sean L. Hammond, Bryce A. Jorgensen, Aaron T. Phillips, Stephen Safe and Ronald B. Tjalkens
    Molecular Pharmacology June 2015, 87 (6) 1021-1034; DOI: https://doi.org/10.1124/mol.114.095398
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    Brainstem Brain-Derived Neurotrophic Factor Signaling Is Required for Histone Deacetylase Inhibitor–Induced Pain Relief
    Wenjuan Tao, Quan Chen, Lu Wang, Wenjie Zhou, Yunping Wang and Zhi Zhang
    Molecular Pharmacology June 2015, 87 (6) 1035-1041; DOI: https://doi.org/10.1124/mol.115.098186
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    The Link between Inactivation and High-Affinity Block of hERG1 Channels
    Wei Wu, Alison Gardner and Michael C. Sanguinetti
    Molecular Pharmacology June 2015, 87 (6) 1042-1050; DOI: https://doi.org/10.1124/mol.115.098111
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In this issue

Molecular Pharmacology: 87 (6)
Molecular Pharmacology
Vol. 87, Issue 6
1 Jun 2015
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  • The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints
  • Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases
  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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