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Molecular Pharmacology

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Table of Contents

July 01, 2015; Volume 88,Issue 1

Special Issue Commemorating the 50th Anniversary of Molecular Pharmacology
Graeme Milligan and Stuart Cull-Candy, Guest Editors

  • The First 50 Years of Molecular Pharmacology
    You have access
    The First 50 Years of Molecular Pharmacology
    Joan Heller Brown, William A. Catterall, P. Jeffrey Conn, Stuart G. Cull-Candy, Ray Dingledine, T. Kendall Harden, Paul A. Insel, Graeme Milligan and Stephen F. Traynelis
    Molecular Pharmacology July 2015, 88 (1) 139-140; DOI: https://doi.org/10.1124/mol.115.099564
  • Structural Basis for Pharmacology of Voltage-Gated Sodium and Calcium Channels
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    Structural Basis for Pharmacology of Voltage-Gated Sodium and Calcium Channels
    William A. Catterall and Teresa M. Swanson
    Molecular Pharmacology July 2015, 88 (1) 141-150; DOI: https://doi.org/10.1124/mol.114.097659
  • UDP-Sugars as Extracellular Signaling Molecules: Cellular and Physiologic Consequences of P2Y<sub>14</sub> Receptor Activation
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    UDP-Sugars as Extracellular Signaling Molecules: Cellular and Physiologic Consequences of P2Y14 Receptor Activation
    Eduardo R. Lazarowski and T. Kendall Harden
    Molecular Pharmacology July 2015, 88 (1) 151-160; DOI: https://doi.org/10.1124/mol.115.098756
  • EP2 Receptor Signaling Regulates Microglia Death
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    EP2 Receptor Signaling Regulates Microglia Death
    Yujiao Fu, Myung-Soon Yang, Jianxiong Jiang, Thota Ganesh, Eunhye Joe and Raymond Dingledine
    Molecular Pharmacology July 2015, 88 (1) 161-170; DOI: https://doi.org/10.1124/mol.115.098202
  • G Protein–Coupled Receptor and RhoA-Stimulated Transcriptional Responses: Links to Inflammation, Differentiation, and Cell Proliferation
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    G Protein–Coupled Receptor and RhoA-Stimulated Transcriptional Responses: Links to Inflammation, Differentiation, and Cell Proliferation
    Olivia M. Yu and Joan Heller Brown
    Molecular Pharmacology July 2015, 88 (1) 171-180; DOI: https://doi.org/10.1124/mol.115.097857
  • G Protein–Coupled Receptor (GPCR) Expression in Native Cells: “Novel” endoGPCRs as Physiologic Regulators and Therapeutic Targets
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    G Protein–Coupled Receptor (GPCR) Expression in Native Cells: “Novel” endoGPCRs as Physiologic Regulators and Therapeutic Targets
    Paul A. Insel, Andrea Wilderman, Alexander C. Zambon, Aaron N. Snead, Fiona Murray, Nakon Aroonsakool, Daniel S. McDonald, Shu Zhou, Thalia McCann, Lingzhi Zhang, Krishna Sriram, Amy M. Chinn, Alexander V. Michkov, Rebecca M. Lynch, Aaron C. Overland and Ross Corriden
    Molecular Pharmacology July 2015, 88 (1) 181-187; DOI: https://doi.org/10.1124/mol.115.098129
  • Molecular Insights into Metabotropic Glutamate Receptor Allosteric Modulation
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    Molecular Insights into Metabotropic Glutamate Receptor Allosteric Modulation
    Karen J. Gregory and P. Jeffrey Conn
    Molecular Pharmacology July 2015, 88 (1) 188-202; DOI: https://doi.org/10.1124/mol.114.097220
  • Ionotropic GABA and Glutamate Receptor Mutations and Human Neurologic Diseases
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    Ionotropic GABA and Glutamate Receptor Mutations and Human Neurologic Diseases
    Hongjie Yuan, Chian-Ming Low, Olivia A. Moody, Andrew Jenkins and Stephen F. Traynelis
    Molecular Pharmacology July 2015, 88 (1) 203-217; DOI: https://doi.org/10.1124/mol.115.097998

Announcement

  • You have access
    ASPET Journals Support the National Institutes of Health Principles and Guidelines for Reporting Preclinical Research
    Molecular Pharmacology July 2015, 88 (1) 218-219; DOI: https://doi.org/10.1124/mol.115.099952

Articles

  • You have access
    Desformylflustrabromine (dFBr) and [3H]dFBr-Labeled Binding Sites in a Nicotinic Acetylcholine Receptor
    Ayman K. Hamouda, Ze-Jun Wang, Deirdre S. Stewart, Atul D. Jain, Richard A. Glennon and Jonathan B. Cohen
    Molecular Pharmacology July 2015, 88 (1) 1-11; DOI: https://doi.org/10.1124/mol.115.098913
  • Ligand Selectivity among the Dopamine and Serotonin Transporters Specified by the Forward Binding Reaction
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    Ligand Selectivity among the Dopamine and Serotonin Transporters Specified by the Forward Binding Reaction
    Peter S. Hasenhuetl, Klaus Schicker, Xaver Koenig, Yang Li, Subhodeep Sarker, Thomas Stockner, Sonja Sucic, Harald H. Sitte, Michael Freissmuth and Walter Sandtner
    Molecular Pharmacology July 2015, 88 (1) 12-18; DOI: https://doi.org/10.1124/mol.115.099036
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    C-Linker Accounts for Differential Sensitivity of ERG1 and ERG2 K+ Channels to RPR260243-Induced Slow Deactivation
    Alison Gardner and Michael C. Sanguinetti
    Molecular Pharmacology July 2015, 88 (1) 19-28; DOI: https://doi.org/10.1124/mol.115.098384
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    Circadian Modulation in the Intestinal Absorption of P-Glycoprotein Substrates in Monkeys
    Masaru Iwasaki, Satoru Koyanagi, Norio Suzuki, Chiharu Katamune, Naoya Matsunaga, Nobuaki Watanabe, Masayuki Takahashi, Takashi Izumi and Shigehiro Ohdo
    Molecular Pharmacology July 2015, 88 (1) 29-37; DOI: https://doi.org/10.1124/mol.114.096735
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    A Sexual Dimorphism Influences Bicyclol-Induced Hepatic Heat Shock Factor 1 Activation and Hepatoprotection
    Xiaosong Chen, Jianjian Zhang, Conghui Han, Huijuan Dai, Xianming Kong, Longmei Xu, Qiang Xia, Ming Zhang and Jianjun Zhang
    Molecular Pharmacology July 2015, 88 (1) 38-47; DOI: https://doi.org/10.1124/mol.114.097584
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    Antiobesity Effect of a Small Molecule Repressor of RORγ
    Mi Ra Chang, Yuanjun He, Tanya M. Khan, Dana S. Kuruvilla, Ruben Garcia-Ordonez, Cesar A. Corzo, Thaddeus J. Unger, David W. White, Susan Khan, Li Lin, Michael D. Cameron, Theodore M. Kamenecka and Patrick R. Griffin
    Molecular Pharmacology July 2015, 88 (1) 48-56; DOI: https://doi.org/10.1124/mol.114.097485
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    Essential Role of Calmodulin in RyR Inhibition by Dantrolene
    Ye Win Oo, Nieves Gomez-Hurtado, Kafa Walweel, Dirk F. van Helden, Mohammad S. Imtiaz, Bjorn C. Knollmann and Derek R. Laver
    Molecular Pharmacology July 2015, 88 (1) 57-63; DOI: https://doi.org/10.1124/mol.115.097691
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    CB1 Knockout Mice Unveil Sustained CB2-Mediated Antiallodynic Effects of the Mixed CB1/CB2 Agonist CP55,940 in a Mouse Model of Paclitaxel-Induced Neuropathic Pain
    Liting Deng, Benjamin L. Cornett, Ken Mackie and Andrea G. Hohmann
    Molecular Pharmacology July 2015, 88 (1) 64-74; DOI: https://doi.org/10.1124/mol.115.098483
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    Targeted Disruption of Organic Cation Transporter 3 Attenuates the Pharmacologic Response to Metformin
    Eugene C. Chen, Xiaomin Liang, Sook Wah Yee, Ethan G. Geier, Sophie L. Stocker, Ligong Chen and Kathleen M. Giacomini
    Molecular Pharmacology July 2015, 88 (1) 75-83; DOI: https://doi.org/10.1124/mol.114.096776
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    ATP–Binding Cassette Transporter Structure Changes Detected by Intramolecular Fluorescence Energy Transfer for High-Throughput Screening
    Surtaj H. Iram, Simon J. Gruber, Olga N. Raguimova, David D. Thomas and Seth L. Robia
    Molecular Pharmacology July 2015, 88 (1) 84-94; DOI: https://doi.org/10.1124/mol.114.096792
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    Characterization of Thrombin-Bound Dabigatran Effects on Protease-Activated Receptor-1 Expression and Signaling In Vitro
    Buxin Chen, Antonio G. Soto, Luisa J. Coronel, Ashley Goss, Joanne van Ryn and JoAnn Trejo
    Molecular Pharmacology July 2015, 88 (1) 95-105; DOI: https://doi.org/10.1124/mol.114.096446
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    Estrogen-Induced Cholestasis Leads to Repressed CYP2D6 Expression in CYP2D6-Humanized Mice
    Xian Pan and Hyunyoung Jeong
    Molecular Pharmacology July 2015, 88 (1) 106-112; DOI: https://doi.org/10.1124/mol.115.098822
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    The ClC-7 Chloride Channel Is Downregulated by Hypoosmotic Stress in Human Chondrocytes
    Takashi Kurita, Hisao Yamamura, Yoshiaki Suzuki, Wayne R. Giles and Yuji Imaizumi
    Molecular Pharmacology July 2015, 88 (1) 113-120; DOI: https://doi.org/10.1124/mol.115.098160
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    KU675, a Concomitant Heat-Shock Protein Inhibitor of Hsp90 and Hsc70 that Manifests Isoform Selectivity for Hsp90α in Prostate Cancer Cells
    Weiya Liu, George A. Vielhauer, Jeffrey M. Holzbeierlein, Huiping Zhao, Suman Ghosh, Douglas Brown, Eugene Lee and Brian S. J. Blagg
    Molecular Pharmacology July 2015, 88 (1) 121-130; DOI: https://doi.org/10.1124/mol.114.097303
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    The Pore Loop Domain of TRPV1 Is Required for Its Activation by the Volatile Anesthetics Chloroform and Isoflurane
    Corinna Kimball, Jialie Luo, Shijin Yin, Hongzhen Hu and Ajay Dhaka
    Molecular Pharmacology July 2015, 88 (1) 131-138; DOI: https://doi.org/10.1124/mol.115.098277
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In this issue

Molecular Pharmacology: 88 (1)
Molecular Pharmacology
Vol. 88, Issue 1
1 Jul 2015
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Editorial Board (PDF)
  • Front Matter (PDF)
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  • Special Issue Commemorating the 50th Anniversary of Molecular Pharmacology
    Graeme Milligan and Stuart Cull-Candy, Guest Editors
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  • SB-431542 Is a Potent and Specific Inhibitor of Transforming Growth Factor-β Superfamily Type I Activin Receptor-Like Kinase (ALK) Receptors ALK4, ALK5, and ALK7
  • The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints
  • Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases
  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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