Rapid CommunicationSpecial Issue Commemorating the 50th Anniversary of Molecular Pharmacology
G Protein–Coupled Receptor (GPCR) Expression in Native Cells: “Novel” endoGPCRs as Physiologic Regulators and Therapeutic Targets
Paul A. Insel, Andrea Wilderman, Alexander C. Zambon, Aaron N. Snead, Fiona Murray, Nakon Aroonsakool, Daniel S. McDonald, Shu Zhou, Thalia McCann, Lingzhi Zhang, Krishna Sriram, Amy M. Chinn, Alexander V. Michkov, Rebecca M. Lynch, Aaron C. Overland and Ross Corriden
Molecular Pharmacology July 2015, 88 (1) 181-187; DOI: https://doi.org/10.1124/mol.115.098129
Paul A. Insel
Departments of Pharmacology (P.A.I., A.W., A.C.Z., A.N.S., N.A., D.S.M., S.Z., T.M., L.Z., K.S., A.M.C., A.V.M., R.M.L., A.C.O., R.C.) and Medicine (P.A.I., F.M.), University of California, San Diego, La Jolla, California
Andrea Wilderman
Departments of Pharmacology (P.A.I., A.W., A.C.Z., A.N.S., N.A., D.S.M., S.Z., T.M., L.Z., K.S., A.M.C., A.V.M., R.M.L., A.C.O., R.C.) and Medicine (P.A.I., F.M.), University of California, San Diego, La Jolla, California
Alexander C. Zambon
Departments of Pharmacology (P.A.I., A.W., A.C.Z., A.N.S., N.A., D.S.M., S.Z., T.M., L.Z., K.S., A.M.C., A.V.M., R.M.L., A.C.O., R.C.) and Medicine (P.A.I., F.M.), University of California, San Diego, La Jolla, California
Aaron N. Snead
Departments of Pharmacology (P.A.I., A.W., A.C.Z., A.N.S., N.A., D.S.M., S.Z., T.M., L.Z., K.S., A.M.C., A.V.M., R.M.L., A.C.O., R.C.) and Medicine (P.A.I., F.M.), University of California, San Diego, La Jolla, California
Fiona Murray
Departments of Pharmacology (P.A.I., A.W., A.C.Z., A.N.S., N.A., D.S.M., S.Z., T.M., L.Z., K.S., A.M.C., A.V.M., R.M.L., A.C.O., R.C.) and Medicine (P.A.I., F.M.), University of California, San Diego, La Jolla, California
Nakon Aroonsakool
Departments of Pharmacology (P.A.I., A.W., A.C.Z., A.N.S., N.A., D.S.M., S.Z., T.M., L.Z., K.S., A.M.C., A.V.M., R.M.L., A.C.O., R.C.) and Medicine (P.A.I., F.M.), University of California, San Diego, La Jolla, California
Daniel S. McDonald
Departments of Pharmacology (P.A.I., A.W., A.C.Z., A.N.S., N.A., D.S.M., S.Z., T.M., L.Z., K.S., A.M.C., A.V.M., R.M.L., A.C.O., R.C.) and Medicine (P.A.I., F.M.), University of California, San Diego, La Jolla, California
Shu Zhou
Departments of Pharmacology (P.A.I., A.W., A.C.Z., A.N.S., N.A., D.S.M., S.Z., T.M., L.Z., K.S., A.M.C., A.V.M., R.M.L., A.C.O., R.C.) and Medicine (P.A.I., F.M.), University of California, San Diego, La Jolla, California
Thalia McCann
Departments of Pharmacology (P.A.I., A.W., A.C.Z., A.N.S., N.A., D.S.M., S.Z., T.M., L.Z., K.S., A.M.C., A.V.M., R.M.L., A.C.O., R.C.) and Medicine (P.A.I., F.M.), University of California, San Diego, La Jolla, California
Lingzhi Zhang
Departments of Pharmacology (P.A.I., A.W., A.C.Z., A.N.S., N.A., D.S.M., S.Z., T.M., L.Z., K.S., A.M.C., A.V.M., R.M.L., A.C.O., R.C.) and Medicine (P.A.I., F.M.), University of California, San Diego, La Jolla, California
Krishna Sriram
Departments of Pharmacology (P.A.I., A.W., A.C.Z., A.N.S., N.A., D.S.M., S.Z., T.M., L.Z., K.S., A.M.C., A.V.M., R.M.L., A.C.O., R.C.) and Medicine (P.A.I., F.M.), University of California, San Diego, La Jolla, California
Amy M. Chinn
Departments of Pharmacology (P.A.I., A.W., A.C.Z., A.N.S., N.A., D.S.M., S.Z., T.M., L.Z., K.S., A.M.C., A.V.M., R.M.L., A.C.O., R.C.) and Medicine (P.A.I., F.M.), University of California, San Diego, La Jolla, California
Alexander V. Michkov
Departments of Pharmacology (P.A.I., A.W., A.C.Z., A.N.S., N.A., D.S.M., S.Z., T.M., L.Z., K.S., A.M.C., A.V.M., R.M.L., A.C.O., R.C.) and Medicine (P.A.I., F.M.), University of California, San Diego, La Jolla, California
Rebecca M. Lynch
Departments of Pharmacology (P.A.I., A.W., A.C.Z., A.N.S., N.A., D.S.M., S.Z., T.M., L.Z., K.S., A.M.C., A.V.M., R.M.L., A.C.O., R.C.) and Medicine (P.A.I., F.M.), University of California, San Diego, La Jolla, California
Aaron C. Overland
Departments of Pharmacology (P.A.I., A.W., A.C.Z., A.N.S., N.A., D.S.M., S.Z., T.M., L.Z., K.S., A.M.C., A.V.M., R.M.L., A.C.O., R.C.) and Medicine (P.A.I., F.M.), University of California, San Diego, La Jolla, California
Ross Corriden
Departments of Pharmacology (P.A.I., A.W., A.C.Z., A.N.S., N.A., D.S.M., S.Z., T.M., L.Z., K.S., A.M.C., A.V.M., R.M.L., A.C.O., R.C.) and Medicine (P.A.I., F.M.), University of California, San Diego, La Jolla, California
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In this issue
Rapid CommunicationSpecial Issue Commemorating the 50th Anniversary of Molecular Pharmacology
Assessing GPCR Expression in Native Cells
Paul A. Insel, Andrea Wilderman, Alexander C. Zambon, Aaron N. Snead, Fiona Murray, Nakon Aroonsakool, Daniel S. McDonald, Shu Zhou, Thalia McCann, Lingzhi Zhang, Krishna Sriram, Amy M. Chinn, Alexander V. Michkov, Rebecca M. Lynch, Aaron C. Overland and Ross Corriden
Molecular Pharmacology July 1, 2015, 88 (1) 181-187; DOI: https://doi.org/10.1124/mol.115.098129
Rapid CommunicationSpecial Issue Commemorating the 50th Anniversary of Molecular Pharmacology
Assessing GPCR Expression in Native Cells
Paul A. Insel, Andrea Wilderman, Alexander C. Zambon, Aaron N. Snead, Fiona Murray, Nakon Aroonsakool, Daniel S. McDonald, Shu Zhou, Thalia McCann, Lingzhi Zhang, Krishna Sriram, Amy M. Chinn, Alexander V. Michkov, Rebecca M. Lynch, Aaron C. Overland and Ross Corriden
Molecular Pharmacology July 1, 2015, 88 (1) 181-187; DOI: https://doi.org/10.1124/mol.115.098129
Jump to section
- Article
- Visual Overview
- Abstract
- Introduction
- Methods and Approaches to Assess GPCR Expression
- Microarrays for the Detection of GPCRs
- What Do Available Data Reveal about GPCR Expression in Tissues and Native Cells?
- What Are Some of the Problems and Limitations of Efforts to Define GPCR Expression in Tissues and Cells?
- Summary and Conclusions
- Acknowledgments
- Authorship Contributions
- Footnotes
- Abbreviations
- References
- Figures & Data
- Info & Metrics
- eLetters
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