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Molecular Pharmacology

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Table of Contents

September 01, 2015; Volume 88,Issue 3

Special Section on Exploring the biology of GPCRs: from in vitro to in vivo

  • Exploring the Biology of G Protein–Coupled Receptors from In Vitro to In Vivo
    You have access
    Exploring the Biology of G Protein–Coupled Receptors from In Vitro to In Vivo
    Laura M. Bohn, Martin J. Lohse, Michael N. Nitabach, Paul H. Taghert and Martine J. Smit
    Molecular Pharmacology September 2015, 88 (3) 534-535; DOI: https://doi.org/10.1124/mol.115.100750
  • A Molecular Pharmacologist’s Guide to G Protein–Coupled Receptor Crystallography
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    A Molecular Pharmacologist’s Guide to G Protein–Coupled Receptor Crystallography
    Chayne L. Piscitelli, James Kean, Chris de Graaf and Xavier Deupi
    Molecular Pharmacology September 2015, 88 (3) 536-551; DOI: https://doi.org/10.1124/mol.115.099663
  • Ligand Residence Time at G-protein–Coupled Receptors—Why We Should Take Our Time To Study It
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    Ligand Residence Time at G-protein–Coupled Receptors—Why We Should Take Our Time To Study It
    C. Hoffmann, M. Castro, A. Rinken, R. Leurs, S. J. Hill and H. F. Vischer
    Molecular Pharmacology September 2015, 88 (3) 552-560; DOI: https://doi.org/10.1124/mol.115.099671
  • G Protein–Coupled Receptor Multimers: A Question Still Open Despite the Use of Novel Approaches
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    G Protein–Coupled Receptor Multimers: A Question Still Open Despite the Use of Novel Approaches
    Henry F. Vischer, Marián Castro and Jean-Philippe Pin
    Molecular Pharmacology September 2015, 88 (3) 561-571; DOI: https://doi.org/10.1124/mol.115.099440
  • Spatial and Temporal Aspects of Signaling by G-Protein–Coupled Receptors
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    Spatial and Temporal Aspects of Signaling by G-Protein–Coupled Receptors
    Martin J. Lohse and Klaus Peter Hofmann
    Molecular Pharmacology September 2015, 88 (3) 572-578; DOI: https://doi.org/10.1124/mol.115.100248
  • Fulfilling the Promise of "Biased" G Protein–Coupled Receptor Agonism
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    Fulfilling the Promise of "Biased" G Protein–Coupled Receptor Agonism
    Louis M. Luttrell, Stuart Maudsley and Laura M. Bohn
    Molecular Pharmacology September 2015, 88 (3) 579-588; DOI: https://doi.org/10.1124/mol.115.099630
  • A Perspective on Studying G-Protein–Coupled Receptor Signaling with Resonance Energy Transfer Biosensors in Living Organisms
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    A Perspective on Studying G-Protein–Coupled Receptor Signaling with Resonance Energy Transfer Biosensors in Living Organisms
    Jakobus van Unen, Jeanette Woolard, Ago Rinken, Carsten Hoffmann, Stephen J. Hill, Joachim Goedhart, Michael R. Bruchas, Michel Bouvier and Merel J. W. Adjobo-Hermans
    Molecular Pharmacology September 2015, 88 (3) 589-595; DOI: https://doi.org/10.1124/mol.115.098897
  • Model Organisms in G Protein–Coupled Receptor Research
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    Model Organisms in G Protein–Coupled Receptor Research
    Tobias Langenhan, Maureen M. Barr, Michael R. Bruchas, John Ewer, Leslie C. Griffith, Isabella Maiellaro, Paul H. Taghert, Benjamin H. White and Kelly R. Monk
    Molecular Pharmacology September 2015, 88 (3) 596-603; DOI: https://doi.org/10.1124/mol.115.098764
  • G Protein–Coupled Receptor Signaling Networks from a Systems Perspective
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    G Protein–Coupled Receptor Signaling Networks from a Systems Perspective
    S. Roth, B. N. Kholodenko, M. J. Smit and F. J. Bruggeman
    Molecular Pharmacology September 2015, 88 (3) 604-616; DOI: https://doi.org/10.1124/mol.115.100057
  • Adhesion G Protein–Coupled Receptors: From In Vitro Pharmacology to In Vivo Mechanisms
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    Adhesion G Protein–Coupled Receptors: From In Vitro Pharmacology to In Vivo Mechanisms
    Kelly R. Monk, Jörg Hamann, Tobias Langenhan, Saskia Nijmeijer, Torsten Schöneberg and Ines Liebscher
    Molecular Pharmacology September 2015, 88 (3) 617-623; DOI: https://doi.org/10.1124/mol.115.098749

Articles

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    Inhibition of Peroxidase Activity of Cytochrome c: De Novo Compound Discovery and Validation
    Ahmet Bakan, Alexandr A. Kapralov, Hulya Bayir, Feizhou Hu, Valerian E. Kagan and Ivet Bahar
    Molecular Pharmacology September 2015, 88 (3) 421-427; DOI: https://doi.org/10.1124/mol.115.097816
  • You have access
    Marketed Drugs Can Inhibit Cytochrome P450 27A1, a Potential New Target for Breast Cancer Adjuvant Therapy
    Natalia Mast, Joseph B. Lin and Irina A. Pikuleva
    Molecular Pharmacology September 2015, 88 (3) 428-436; DOI: https://doi.org/10.1124/mol.115.099598
  • You have access
    Sequential Upregulation of Superoxide Dismutase 2 and Heme Oxygenase 1 by tert-Butylhydroquinone Protects Mitochondria during Oxidative Stress
    Jiahong Sun, Xuefang Ren and James W. Simpkins
    Molecular Pharmacology September 2015, 88 (3) 437-449; DOI: https://doi.org/10.1124/mol.115.098269
  • You have access
    Chloride is an Agonist of Group II and III Metabotropic Glutamate Receptors
    John O. DiRaddo, Eric J. Miller, Carrie Bowman-Dalley, Barbara Wroblewska, Monica Javidnia, Ewa Grajkowska, Barry B. Wolfe, Dennis C. Liotta and Jarda T. Wroblewski
    Molecular Pharmacology September 2015, 88 (3) 450-459; DOI: https://doi.org/10.1124/mol.114.096420
  • You have access
    A Positive Allosteric Modulator of the Adenosine A1 Receptor Selectively Inhibits Primary Afferent Synaptic Transmission in a Neuropathic Pain Model
    Wendy L. Imlach, Rebecca F. Bhola, Lauren T. May, Arthur Christopoulos and Macdonald J. Christie
    Molecular Pharmacology September 2015, 88 (3) 460-468; DOI: https://doi.org/10.1124/mol.115.099499
  • You have access
    cAMP-Dependent Protein Kinase A (PKA)–Mediated c-Myc Degradation Is Dependent on the Relative Proportion of PKA-I and PKA-II Isozymes
    Qingyuan Liu, Eric Nguyen, Stein Døskeland and Évelyne Ségal-Bendirdjian
    Molecular Pharmacology September 2015, 88 (3) 469-476; DOI: https://doi.org/10.1124/mol.115.097915
  • You have access
    Lysosomal Sequestration Determines Intracellular Imatinib Levels
    Herman Burger, Alexander T. den Dekker, Sandra Segeletz, Antonius W. M. Boersma, Peter de Bruijn, Maria Debiec-Rychter, Takahiro Taguchi, Stefan Sleijfer, Alex Sparreboom, Ron H. J. Mathijssen and Erik A. C. Wiemer
    Molecular Pharmacology September 2015, 88 (3) 477-487; DOI: https://doi.org/10.1124/mol.114.097451
  • You have access
    Structure-Function Basis of Attenuated Inverse Agonism of Angiotensin II Type 1 Receptor Blockers for Active-State Angiotensin II Type 1 Receptor
    Takanobu Takezako, Hamiyet Unal, Sadashiva S. Karnik and Koichi Node
    Molecular Pharmacology September 2015, 88 (3) 488-501; DOI: https://doi.org/10.1124/mol.115.099176
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    Quantitative Signaling and Structure-Activity Analyses Demonstrate Functional Selectivity at the Nociceptin/Orphanin FQ Opioid Receptor
    Steven D. Chang, S. Wayne Mascarella, Skylar M. Spangler, Vsevolod V. Gurevich, Hernan A. Navarro, F. Ivy Carroll and Michael R. Bruchas
    Molecular Pharmacology September 2015, 88 (3) 502-511; DOI: https://doi.org/10.1124/mol.115.099150
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    Targeted Inhibition of Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Sensitizes Pancreatic Cancer Cells to Doxorubicin without Exacerbating Cardiac Toxicity
    David E. Durrant, Anindita Das, Samya Dyer, Seyedmehrad Tavallai, Paul Dent and Rakesh C. Kukreja
    Molecular Pharmacology September 2015, 88 (3) 512-523; DOI: https://doi.org/10.1124/mol.115.099143
  • A Resveratrol Analogue Promotes ERK<sup>MAPK</sup>–Dependent Stat3 Serine and Tyrosine Phosphorylation Alterations and Antitumor Effects In Vitro against Human Tumor Cells
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    A Resveratrol Analogue Promotes ERKMAPK–Dependent Stat3 Serine and Tyrosine Phosphorylation Alterations and Antitumor Effects In Vitro against Human Tumor Cells
    Zachary L. Chelsky, Peibin Yue, Tamara P. Kondratyuk, David Paladino, John M. Pezzuto, Mark Cushman and James Turkson
    Molecular Pharmacology September 2015, 88 (3) 524-533; DOI: https://doi.org/10.1124/mol.115.099093
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In this issue

Molecular Pharmacology: 88 (3)
Molecular Pharmacology
Vol. 88, Issue 3
1 Sep 2015
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
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  • Editorial Board (PDF)
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