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Research ArticleArticle

Substrate and Inhibitor–Specific Conformational Changes in the Human Serotonin Transporter Revealed by Voltage-Clamp Fluorometry

Pella C. Söderhielm, Jacob Andersen, Lachlan Munro, Anne T. Nielsen and Anders S. Kristensen
Molecular Pharmacology October 2015, 88 (4) 676-688; DOI: https://doi.org/10.1124/mol.115.099911
Pella C. Söderhielm
Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark
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Jacob Andersen
Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark
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Lachlan Munro
Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark
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Anne T. Nielsen
Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark
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Anders S. Kristensen
Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark
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Article Information

vol. 88 no. 4 676-688
DOI 
https://doi.org/10.1124/mol.115.099911
PubMed 
26174773

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received May 13, 2015
  • Accepted July 13, 2015
  • Published online August 21, 2015.

Article Versions

  • Earlier version (July 14, 2015 - 06:27).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2015 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Pella C. Söderhielm,
  2. Jacob Andersen,
  3. Lachlan Munro,
  4. Anne T. Nielsen, and
  5. Anders S. Kristensen
  1. Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark
  1. Address correspondence to:
    Anders S. Kristensen, Department of Drug Design and Pharmacology, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark. E-mail: ask{at}sund.ku.dk
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Molecular Pharmacology: 88 (4)
Molecular Pharmacology
Vol. 88, Issue 4
1 Oct 2015
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Research ArticleArticle

Structural Correlates of Inhibitor Function at hSERT

Pella C. Söderhielm, Jacob Andersen, Lachlan Munro, Anne T. Nielsen and Anders S. Kristensen
Molecular Pharmacology October 1, 2015, 88 (4) 676-688; DOI: https://doi.org/10.1124/mol.115.099911

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Research ArticleArticle

Structural Correlates of Inhibitor Function at hSERT

Pella C. Söderhielm, Jacob Andersen, Lachlan Munro, Anne T. Nielsen and Anders S. Kristensen
Molecular Pharmacology October 1, 2015, 88 (4) 676-688; DOI: https://doi.org/10.1124/mol.115.099911
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