Research ArticleArticle
Preclinical Evaluation of DMA, a Bisbenzimidazole, as Radioprotector: Toxicity, Pharmacokinetics, and Biodistribution Studies in Balb/c Mice
Hemlata Nimesh, Vinod Tiwari, Chunhua Yang, Sushma R. Gundala, Krishna Chuttani, Puja P. Hazari, Anil K. Mishra, Abhisheak Sharma, Jawahar Lal, Anju Katyal, Ritu Aneja and Vibha Tandon
Molecular Pharmacology October 2015, 88 (4) 768-778; DOI: https://doi.org/10.1124/mol.115.098376
Hemlata Nimesh
Chemical Biology Research Laboratory, Special Center for Molecular Medicine, Jawaharlal Nehru University, Delhi, India (V.Ta.); Department of Chemistry, University of Delhi, Delhi, India (H.N., V.Ti., V.Ta.); Department of Biology, Georgia State University, Atlanta, Georgia (C.Y., S.R.G., R.A.); Dr. Ambedkar Center for Biomedical Research, University of Delhi, Delhi, India (A.K.); Division of Cyclotron and Radiopharmaceutical Sciences, Institute of Nuclear Medicine and Allied Sciences, Delhi, India (K.C., P.P.H., A.K.M.); and Pharmacokinetics and Metabolism Division, Council of Scientific and Industrial Research–Central Drug Research Institute, Lucknow, India (A.S., J.L.)
Vinod Tiwari
Chemical Biology Research Laboratory, Special Center for Molecular Medicine, Jawaharlal Nehru University, Delhi, India (V.Ta.); Department of Chemistry, University of Delhi, Delhi, India (H.N., V.Ti., V.Ta.); Department of Biology, Georgia State University, Atlanta, Georgia (C.Y., S.R.G., R.A.); Dr. Ambedkar Center for Biomedical Research, University of Delhi, Delhi, India (A.K.); Division of Cyclotron and Radiopharmaceutical Sciences, Institute of Nuclear Medicine and Allied Sciences, Delhi, India (K.C., P.P.H., A.K.M.); and Pharmacokinetics and Metabolism Division, Council of Scientific and Industrial Research–Central Drug Research Institute, Lucknow, India (A.S., J.L.)
Chunhua Yang
Chemical Biology Research Laboratory, Special Center for Molecular Medicine, Jawaharlal Nehru University, Delhi, India (V.Ta.); Department of Chemistry, University of Delhi, Delhi, India (H.N., V.Ti., V.Ta.); Department of Biology, Georgia State University, Atlanta, Georgia (C.Y., S.R.G., R.A.); Dr. Ambedkar Center for Biomedical Research, University of Delhi, Delhi, India (A.K.); Division of Cyclotron and Radiopharmaceutical Sciences, Institute of Nuclear Medicine and Allied Sciences, Delhi, India (K.C., P.P.H., A.K.M.); and Pharmacokinetics and Metabolism Division, Council of Scientific and Industrial Research–Central Drug Research Institute, Lucknow, India (A.S., J.L.)
Sushma R. Gundala
Chemical Biology Research Laboratory, Special Center for Molecular Medicine, Jawaharlal Nehru University, Delhi, India (V.Ta.); Department of Chemistry, University of Delhi, Delhi, India (H.N., V.Ti., V.Ta.); Department of Biology, Georgia State University, Atlanta, Georgia (C.Y., S.R.G., R.A.); Dr. Ambedkar Center for Biomedical Research, University of Delhi, Delhi, India (A.K.); Division of Cyclotron and Radiopharmaceutical Sciences, Institute of Nuclear Medicine and Allied Sciences, Delhi, India (K.C., P.P.H., A.K.M.); and Pharmacokinetics and Metabolism Division, Council of Scientific and Industrial Research–Central Drug Research Institute, Lucknow, India (A.S., J.L.)
Krishna Chuttani
Chemical Biology Research Laboratory, Special Center for Molecular Medicine, Jawaharlal Nehru University, Delhi, India (V.Ta.); Department of Chemistry, University of Delhi, Delhi, India (H.N., V.Ti., V.Ta.); Department of Biology, Georgia State University, Atlanta, Georgia (C.Y., S.R.G., R.A.); Dr. Ambedkar Center for Biomedical Research, University of Delhi, Delhi, India (A.K.); Division of Cyclotron and Radiopharmaceutical Sciences, Institute of Nuclear Medicine and Allied Sciences, Delhi, India (K.C., P.P.H., A.K.M.); and Pharmacokinetics and Metabolism Division, Council of Scientific and Industrial Research–Central Drug Research Institute, Lucknow, India (A.S., J.L.)
Puja P. Hazari
Chemical Biology Research Laboratory, Special Center for Molecular Medicine, Jawaharlal Nehru University, Delhi, India (V.Ta.); Department of Chemistry, University of Delhi, Delhi, India (H.N., V.Ti., V.Ta.); Department of Biology, Georgia State University, Atlanta, Georgia (C.Y., S.R.G., R.A.); Dr. Ambedkar Center for Biomedical Research, University of Delhi, Delhi, India (A.K.); Division of Cyclotron and Radiopharmaceutical Sciences, Institute of Nuclear Medicine and Allied Sciences, Delhi, India (K.C., P.P.H., A.K.M.); and Pharmacokinetics and Metabolism Division, Council of Scientific and Industrial Research–Central Drug Research Institute, Lucknow, India (A.S., J.L.)
Anil K. Mishra
Chemical Biology Research Laboratory, Special Center for Molecular Medicine, Jawaharlal Nehru University, Delhi, India (V.Ta.); Department of Chemistry, University of Delhi, Delhi, India (H.N., V.Ti., V.Ta.); Department of Biology, Georgia State University, Atlanta, Georgia (C.Y., S.R.G., R.A.); Dr. Ambedkar Center for Biomedical Research, University of Delhi, Delhi, India (A.K.); Division of Cyclotron and Radiopharmaceutical Sciences, Institute of Nuclear Medicine and Allied Sciences, Delhi, India (K.C., P.P.H., A.K.M.); and Pharmacokinetics and Metabolism Division, Council of Scientific and Industrial Research–Central Drug Research Institute, Lucknow, India (A.S., J.L.)
Abhisheak Sharma
Chemical Biology Research Laboratory, Special Center for Molecular Medicine, Jawaharlal Nehru University, Delhi, India (V.Ta.); Department of Chemistry, University of Delhi, Delhi, India (H.N., V.Ti., V.Ta.); Department of Biology, Georgia State University, Atlanta, Georgia (C.Y., S.R.G., R.A.); Dr. Ambedkar Center for Biomedical Research, University of Delhi, Delhi, India (A.K.); Division of Cyclotron and Radiopharmaceutical Sciences, Institute of Nuclear Medicine and Allied Sciences, Delhi, India (K.C., P.P.H., A.K.M.); and Pharmacokinetics and Metabolism Division, Council of Scientific and Industrial Research–Central Drug Research Institute, Lucknow, India (A.S., J.L.)
Jawahar Lal
Chemical Biology Research Laboratory, Special Center for Molecular Medicine, Jawaharlal Nehru University, Delhi, India (V.Ta.); Department of Chemistry, University of Delhi, Delhi, India (H.N., V.Ti., V.Ta.); Department of Biology, Georgia State University, Atlanta, Georgia (C.Y., S.R.G., R.A.); Dr. Ambedkar Center for Biomedical Research, University of Delhi, Delhi, India (A.K.); Division of Cyclotron and Radiopharmaceutical Sciences, Institute of Nuclear Medicine and Allied Sciences, Delhi, India (K.C., P.P.H., A.K.M.); and Pharmacokinetics and Metabolism Division, Council of Scientific and Industrial Research–Central Drug Research Institute, Lucknow, India (A.S., J.L.)
Anju Katyal
Chemical Biology Research Laboratory, Special Center for Molecular Medicine, Jawaharlal Nehru University, Delhi, India (V.Ta.); Department of Chemistry, University of Delhi, Delhi, India (H.N., V.Ti., V.Ta.); Department of Biology, Georgia State University, Atlanta, Georgia (C.Y., S.R.G., R.A.); Dr. Ambedkar Center for Biomedical Research, University of Delhi, Delhi, India (A.K.); Division of Cyclotron and Radiopharmaceutical Sciences, Institute of Nuclear Medicine and Allied Sciences, Delhi, India (K.C., P.P.H., A.K.M.); and Pharmacokinetics and Metabolism Division, Council of Scientific and Industrial Research–Central Drug Research Institute, Lucknow, India (A.S., J.L.)
Ritu Aneja
Chemical Biology Research Laboratory, Special Center for Molecular Medicine, Jawaharlal Nehru University, Delhi, India (V.Ta.); Department of Chemistry, University of Delhi, Delhi, India (H.N., V.Ti., V.Ta.); Department of Biology, Georgia State University, Atlanta, Georgia (C.Y., S.R.G., R.A.); Dr. Ambedkar Center for Biomedical Research, University of Delhi, Delhi, India (A.K.); Division of Cyclotron and Radiopharmaceutical Sciences, Institute of Nuclear Medicine and Allied Sciences, Delhi, India (K.C., P.P.H., A.K.M.); and Pharmacokinetics and Metabolism Division, Council of Scientific and Industrial Research–Central Drug Research Institute, Lucknow, India (A.S., J.L.)
Vibha Tandon
Chemical Biology Research Laboratory, Special Center for Molecular Medicine, Jawaharlal Nehru University, Delhi, India (V.Ta.); Department of Chemistry, University of Delhi, Delhi, India (H.N., V.Ti., V.Ta.); Department of Biology, Georgia State University, Atlanta, Georgia (C.Y., S.R.G., R.A.); Dr. Ambedkar Center for Biomedical Research, University of Delhi, Delhi, India (A.K.); Division of Cyclotron and Radiopharmaceutical Sciences, Institute of Nuclear Medicine and Allied Sciences, Delhi, India (K.C., P.P.H., A.K.M.); and Pharmacokinetics and Metabolism Division, Council of Scientific and Industrial Research–Central Drug Research Institute, Lucknow, India (A.S., J.L.)
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Research ArticleArticle
Bisbenzimidazole Pharmacologic Study, DMA as Radioprotector
Hemlata Nimesh, Vinod Tiwari, Chunhua Yang, Sushma R. Gundala, Krishna Chuttani, Puja P. Hazari, Anil K. Mishra, Abhisheak Sharma, Jawahar Lal, Anju Katyal, Ritu Aneja and Vibha Tandon
Molecular Pharmacology October 1, 2015, 88 (4) 768-778; DOI: https://doi.org/10.1124/mol.115.098376
Research ArticleArticle
Bisbenzimidazole Pharmacologic Study, DMA as Radioprotector
Hemlata Nimesh, Vinod Tiwari, Chunhua Yang, Sushma R. Gundala, Krishna Chuttani, Puja P. Hazari, Anil K. Mishra, Abhisheak Sharma, Jawahar Lal, Anju Katyal, Ritu Aneja and Vibha Tandon
Molecular Pharmacology October 1, 2015, 88 (4) 768-778; DOI: https://doi.org/10.1124/mol.115.098376
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