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Research ArticleArticle

Gβγ Binds to the Extreme C Terminus of SNAP25 to Mediate the Action of Gi/o-Coupled G Protein–Coupled Receptors

Zack Zurawski, Shelagh Rodriguez, Karren Hyde, Simon Alford and Heidi E. Hamm
Molecular Pharmacology January 2016, 89 (1) 75-83; DOI: https://doi.org/10.1124/mol.115.101600
Zack Zurawski
Department of Pharmacology, Vanderbilt University Medical Center, Nashville, Tennessee (Z.Z., K.H., H.E.H.); and Department of Biological Sciences, University of Illinois, Chicago, Illinois (S.R., S.A.)
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Shelagh Rodriguez
Department of Pharmacology, Vanderbilt University Medical Center, Nashville, Tennessee (Z.Z., K.H., H.E.H.); and Department of Biological Sciences, University of Illinois, Chicago, Illinois (S.R., S.A.)
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Karren Hyde
Department of Pharmacology, Vanderbilt University Medical Center, Nashville, Tennessee (Z.Z., K.H., H.E.H.); and Department of Biological Sciences, University of Illinois, Chicago, Illinois (S.R., S.A.)
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Simon Alford
Department of Pharmacology, Vanderbilt University Medical Center, Nashville, Tennessee (Z.Z., K.H., H.E.H.); and Department of Biological Sciences, University of Illinois, Chicago, Illinois (S.R., S.A.)
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Heidi E. Hamm
Department of Pharmacology, Vanderbilt University Medical Center, Nashville, Tennessee (Z.Z., K.H., H.E.H.); and Department of Biological Sciences, University of Illinois, Chicago, Illinois (S.R., S.A.)
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Article Information

vol. 89 no. 1 75-83
DOI 
https://doi.org/10.1124/mol.115.101600
PubMed 
26519224

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received September 1, 2015
  • Accepted October 30, 2015
  • Published online December 8, 2015.

Article Versions

  • Earlier version (October 30, 2015 - 11:15).
  • Earlier version (November 6, 2015 - 05:26).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2015 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Zack Zurawski,
  2. Shelagh Rodriguez,
  3. Karren Hyde,
  4. Simon Alford, and
  5. Heidi E. Hamm
  1. Department of Pharmacology, Vanderbilt University Medical Center, Nashville, Tennessee (Z.Z., K.H., H.E.H.); and Department of Biological Sciences, University of Illinois, Chicago, Illinois (S.R., S.A.)
  1. Address correspondence to:
    Heidi E. Hamm, Department of Pharmacology, Vanderbilt University Medical Center, 442 Robinson Research Building, 23rd Ave. South at Pierce, Nashville, TN 37232-6600. E-mail: heidi.hamm{at}vanderbilt.edu
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Molecular Pharmacology: 89 (1)
Molecular Pharmacology
Vol. 89, Issue 1
1 Jan 2016
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Research ArticleArticle

SNAP25 C-terminal Mutants Resistant to Gβγ Inhibition

Zack Zurawski, Shelagh Rodriguez, Karren Hyde, Simon Alford and Heidi E. Hamm
Molecular Pharmacology January 1, 2016, 89 (1) 75-83; DOI: https://doi.org/10.1124/mol.115.101600

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Research ArticleArticle

SNAP25 C-terminal Mutants Resistant to Gβγ Inhibition

Zack Zurawski, Shelagh Rodriguez, Karren Hyde, Simon Alford and Heidi E. Hamm
Molecular Pharmacology January 1, 2016, 89 (1) 75-83; DOI: https://doi.org/10.1124/mol.115.101600
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