Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET

User menu

  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Molecular Pharmacology
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET
  • My alerts
  • Log in
  • My Cart
Molecular Pharmacology

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Visit molpharm on Facebook
  • Follow molpharm on Twitter
  • Follow molpharm on LinkedIn
Research ArticleArticle

Pharmacology and Structural Analysis of Ligand Binding to the Orthosteric Site of Glutamate-Like GluD2 Receptors

Anders S. Kristensen, Kasper B. Hansen, Peter Naur, Lars Olsen, Natalie L. Kurtkaya, Shashank M. Dravid, Trine Kvist, Feng Yi, Jacob Pøhlsgaard, Rasmus P. Clausen, Michael Gajhede, Jette S. Kastrup and Stephen F. Traynelis
Molecular Pharmacology February 2016, 89 (2) 253-262; DOI: https://doi.org/10.1124/mol.115.100909
Anders S. Kristensen
Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia (A.S.K., K.B.H., N.L.K., S.M.D., S.F.T.); Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark (A.S.K., P.N., L.O., T.K., J.P., R.P.C., M.G., J.S.K.); and Department of Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, Montana (K.B.H., F.Y.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Kasper B. Hansen
Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia (A.S.K., K.B.H., N.L.K., S.M.D., S.F.T.); Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark (A.S.K., P.N., L.O., T.K., J.P., R.P.C., M.G., J.S.K.); and Department of Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, Montana (K.B.H., F.Y.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Peter Naur
Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia (A.S.K., K.B.H., N.L.K., S.M.D., S.F.T.); Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark (A.S.K., P.N., L.O., T.K., J.P., R.P.C., M.G., J.S.K.); and Department of Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, Montana (K.B.H., F.Y.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Lars Olsen
Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia (A.S.K., K.B.H., N.L.K., S.M.D., S.F.T.); Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark (A.S.K., P.N., L.O., T.K., J.P., R.P.C., M.G., J.S.K.); and Department of Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, Montana (K.B.H., F.Y.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Natalie L. Kurtkaya
Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia (A.S.K., K.B.H., N.L.K., S.M.D., S.F.T.); Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark (A.S.K., P.N., L.O., T.K., J.P., R.P.C., M.G., J.S.K.); and Department of Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, Montana (K.B.H., F.Y.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Shashank M. Dravid
Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia (A.S.K., K.B.H., N.L.K., S.M.D., S.F.T.); Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark (A.S.K., P.N., L.O., T.K., J.P., R.P.C., M.G., J.S.K.); and Department of Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, Montana (K.B.H., F.Y.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Trine Kvist
Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia (A.S.K., K.B.H., N.L.K., S.M.D., S.F.T.); Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark (A.S.K., P.N., L.O., T.K., J.P., R.P.C., M.G., J.S.K.); and Department of Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, Montana (K.B.H., F.Y.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Feng Yi
Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia (A.S.K., K.B.H., N.L.K., S.M.D., S.F.T.); Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark (A.S.K., P.N., L.O., T.K., J.P., R.P.C., M.G., J.S.K.); and Department of Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, Montana (K.B.H., F.Y.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jacob Pøhlsgaard
Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia (A.S.K., K.B.H., N.L.K., S.M.D., S.F.T.); Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark (A.S.K., P.N., L.O., T.K., J.P., R.P.C., M.G., J.S.K.); and Department of Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, Montana (K.B.H., F.Y.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Rasmus P. Clausen
Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia (A.S.K., K.B.H., N.L.K., S.M.D., S.F.T.); Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark (A.S.K., P.N., L.O., T.K., J.P., R.P.C., M.G., J.S.K.); and Department of Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, Montana (K.B.H., F.Y.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Michael Gajhede
Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia (A.S.K., K.B.H., N.L.K., S.M.D., S.F.T.); Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark (A.S.K., P.N., L.O., T.K., J.P., R.P.C., M.G., J.S.K.); and Department of Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, Montana (K.B.H., F.Y.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jette S. Kastrup
Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia (A.S.K., K.B.H., N.L.K., S.M.D., S.F.T.); Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark (A.S.K., P.N., L.O., T.K., J.P., R.P.C., M.G., J.S.K.); and Department of Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, Montana (K.B.H., F.Y.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Stephen F. Traynelis
Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia (A.S.K., K.B.H., N.L.K., S.M.D., S.F.T.); Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark (A.S.K., P.N., L.O., T.K., J.P., R.P.C., M.G., J.S.K.); and Department of Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, Montana (K.B.H., F.Y.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF + SI
  • PDF
Loading

Article Information

vol. 89 no. 2 253-262
DOI 
https://doi.org/10.1124/mol.115.100909
PubMed 
26661043

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received July 28, 2015
  • Accepted December 7, 2015
  • Published online January 11, 2016.

Article Versions

  • Earlier version (December 10, 2015 - 07:42).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2016 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Anders S. Kristensen,
  2. Kasper B. Hansen,
  3. Peter Naur,
  4. Lars Olsen,
  5. Natalie L. Kurtkaya,
  6. Shashank M. Dravid,
  7. Trine Kvist,
  8. Feng Yi,
  9. Jacob Pøhlsgaard,
  10. Rasmus P. Clausen,
  11. Michael Gajhede,
  12. Jette S. Kastrup, and
  13. Stephen F. Traynelis
  1. Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia (A.S.K., K.B.H., N.L.K., S.M.D., S.F.T.); Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark (A.S.K., P.N., L.O., T.K., J.P., R.P.C., M.G., J.S.K.); and Department of Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, Montana (K.B.H., F.Y.)
  1. Address correspondence to:
    Dr. Stephen F. Traynelis, Department of Pharmacology, Emory University, Rollins Research Center, 1510 Clifton Rd., Atlanta, GA 30322. E-mail: strayne{at}emory.edu or Dr. Jette S. Kastrup, Department of Drug Design and Pharmacology, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark. E-mail: jsk{at}sund.ku.dk
View Full Text

Statistics from Altmetric.com

Article usage

Article usage: December 2015 to January 2023

AbstractFullPdf
Dec 20152042159
Jan 20164613184
Feb 20161552438
Mar 20161122936
Apr 2016491329
May 2016472428
Jun 2016521213
Jul 201634119
Aug 2016431014
Sep 2016211010
Oct 20164082
Nov 201661109
Dec 20162259
Jan 2017121811
Feb 201712715
Mar 2017223348
Apr 201702726
May 201712333
Jun 201741624
Jul 201732616
Aug 201742416
Sep 201731415
Oct 201702113
Nov 201702510
Dec 201702616
Jan 201823531
Feb 201842113
Mar 20180249
Apr 201812312
May 20182207
Jun 201818317
Jul 201801711
Aug 201804010
Sep 201811112
Oct 20180228
Nov 201802613
Dec 201851312
Jan 201901414
Feb 201922020
Mar 201931322
Apr 201912924
May 201902019
Jun 201901112
Jul 201932024
Aug 201902223
Sep 201903214
Oct 201921515
Nov 201912020
Dec 201912120
Jan 202032727
Feb 202012313
Mar 202001212
Apr 202021512
May 202032127
Jun 202011716
Jul 20200233
Aug 202012813
Sep 202022515
Oct 202081511
Nov 202022122
Dec 202071720
Jan 202151822
Feb 202172221
Mar 20215125
Apr 202162019
May 2021171717
Jun 202131814
Jul 202121125
Aug 202171730
Sep 202122216
Oct 202121633
Nov 202112138
Dec 202111917
Jan 2022172829
Feb 20223057
Mar 2022751022
Apr 20225858
May 202225810
Jun 20222435
Jul 20222738
Aug 20222368
Sep 202229127
Oct 202254815
Nov 20223644
Dec 20222765
Jan 20231944

PreviousNext
Back to top

In this issue

Molecular Pharmacology: 89 (2)
Molecular Pharmacology
Vol. 89, Issue 2
1 Feb 2016
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Editorial Board (PDF)
  • Front Matter (PDF)
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for sharing this Molecular Pharmacology article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
Pharmacology and Structural Analysis of Ligand Binding to the Orthosteric Site of Glutamate-Like GluD2 Receptors
(Your Name) has forwarded a page to you from Molecular Pharmacology
(Your Name) thought you would be interested in this article in Molecular Pharmacology.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Research ArticleArticle

Ligands Modulating Activity of the GluD2 Lurcher Mutant

Anders S. Kristensen, Kasper B. Hansen, Peter Naur, Lars Olsen, Natalie L. Kurtkaya, Shashank M. Dravid, Trine Kvist, Feng Yi, Jacob Pøhlsgaard, Rasmus P. Clausen, Michael Gajhede, Jette S. Kastrup and Stephen F. Traynelis
Molecular Pharmacology February 1, 2016, 89 (2) 253-262; DOI: https://doi.org/10.1124/mol.115.100909

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero

Share
Research ArticleArticle

Ligands Modulating Activity of the GluD2 Lurcher Mutant

Anders S. Kristensen, Kasper B. Hansen, Peter Naur, Lars Olsen, Natalie L. Kurtkaya, Shashank M. Dravid, Trine Kvist, Feng Yi, Jacob Pøhlsgaard, Rasmus P. Clausen, Michael Gajhede, Jette S. Kastrup and Stephen F. Traynelis
Molecular Pharmacology February 1, 2016, 89 (2) 253-262; DOI: https://doi.org/10.1124/mol.115.100909
del.icio.us logo Digg logo Reddit logo Twitter logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Introduction
    • Materials and Methods
    • Results
    • Discussion
    • Acknowledgments
    • Authorship Contributions
    • Footnotes
    • Abbreviations
    • References
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF + SI
  • PDF

Related Articles

Cited By...

More in this TOC Section

  • The binding site for KCI807 in the androgen receptor
  • Fatty acid amide hydrolase in cisplatin nephrotoxicity
  • eCB Signaling System in hiPSC-Derived Neuronal Cultures
Show more Articles

Similar Articles

Advertisement
  • Home
  • Alerts
Facebook   Twitter   LinkedIn   RSS

Navigate

  • Current Issue
  • Fast Forward by date
  • Fast Forward by section
  • Latest Articles
  • Archive
  • Search for Articles
  • Feedback
  • ASPET

More Information

  • About Molecular Pharmacology
  • Editorial Board
  • Instructions to Authors
  • Submit a Manuscript
  • Customized Alerts
  • RSS Feeds
  • Subscriptions
  • Permissions
  • Terms & Conditions of Use

ASPET's Other Journals

  • Drug Metabolism and Disposition
  • Journal of Pharmacology and Experimental Therapeutics
  • Pharmacological Reviews
  • Pharmacology Research & Perspectives
ISSN 1521-0111 (Online)

Copyright © 2023 by the American Society for Pharmacology and Experimental Therapeutics