Molecular Pharmacology: 90 (3)

September 01, 2016; Volume 90,Issue 3

Special Section—A Latin American Perspective on Ion Channels

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A Latin American Perspective on Ion Channels
Ana Belén Elgoyhen and Carlos Barajas-López

Molecular Pharmacology September 2016, 90 (3) 286-287; DOI: https://doi.org/10.1124/mol.116.105510
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Understanding the Bases of Function and Modulation of α7 Nicotinic Receptors: Implications for Drug Discovery
Jeremías Corradi and Cecilia Bouzat

Molecular Pharmacology September 2016, 90 (3) 288-299; DOI: https://doi.org/10.1124/mol.116.104240
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Structure-Driven Pharmacology of Transient Receptor Potential Channel Vanilloid 1
Ignacio Díaz-Franulic, Javier Caceres-Molina, Romina V. Sepulveda, Fernando Gonzalez-Nilo and Ramon Latorre

Molecular Pharmacology September 2016, 90 (3) 300-308; DOI: https://doi.org/10.1124/mol.116.104430
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Gating, Regulation, and Structure in K_2P K⁺ Channels: In Varietate Concordia?
María Isabel Niemeyer, L. Pablo Cid, Wendy González and Francisco V. Sepúlveda

Molecular Pharmacology September 2016, 90 (3) 309-317; DOI: https://doi.org/10.1124/mol.116.103895
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Structure and Pharmacologic Modulation of Inhibitory Glycine Receptors
Carlos F. Burgos, Gonzalo E. Yévenes and Luis G. Aguayo

Molecular Pharmacology September 2016, 90 (3) 318-325; DOI: https://doi.org/10.1124/mol.116.105726
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Dynamic Regulation of the GABA_A Receptor Function by Redox Mechanisms
Daniel J. Calvo and Andrea N. Beltrán González

Molecular Pharmacology September 2016, 90 (3) 326-333; DOI: https://doi.org/10.1124/mol.116.105205
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Pharmacological Conversion of a Cardiac Inward Rectifier into an Outward Rectifier Potassium Channel
Eloy G. Moreno-Galindo, Jose A. Sanchez-Chapula, Martin Tristani-Firouzi and Ricardo A. Navarro-Polanco

Molecular Pharmacology September 2016, 90 (3) 334-340; DOI: https://doi.org/10.1124/mol.116.104950
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Modulation of Ionic Channels and Insulin Secretion by Drugs and Hormones in Pancreatic Beta Cells
Myrian Velasco, Carlos Manlio Díaz-García, Carlos Larqué and Marcia Hiriart

Molecular Pharmacology September 2016, 90 (3) 341-357; DOI: https://doi.org/10.1124/mol.116.103861
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Channels and Volume Changes in the Life and Death of the Cell
Herminia Pasantes-Morales

Molecular Pharmacology September 2016, 90 (3) 358-370; DOI: https://doi.org/10.1124/mol.116.104158
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Modulation of Autophagy by Calcium Signalosome in Human Disease
Eduardo Cremonese Filippi-Chiela, Michelle S. Viegas, Marcos Paulo Thomé, Andreia Buffon, Marcia R. Wink and Guido Lenz

Molecular Pharmacology September 2016, 90 (3) 371-384; DOI: https://doi.org/10.1124/mol.116.105171
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Pharmacological Modulation of Proton Channel Hv1 in Cancer Therapy: Future Perspectives
Audry Fernández, Amaury Pupo, Karel Mena-Ulecia and Carlos Gonzalez

Molecular Pharmacology September 2016, 90 (3) 385-402; DOI: https://doi.org/10.1124/mol.116.103804
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Calcium Channels and Associated Receptors in Malignant Brain Tumor Therapy
Fernanda B. Morrone, Marina P. Gehring and Natália F. Nicoletti

Molecular Pharmacology September 2016, 90 (3) 403-409; DOI: https://doi.org/10.1124/mol.116.103770

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Guanylyl Cyclase C Hormone Axis at the Intersection of Obesity and Colorectal Cancer
Erik S. Blomain, Dante J. Merlino, Amanda M. Pattison, Adam E. Snook and Scott A. Waldman

Molecular Pharmacology September 2016, 90 (3) 199-204; DOI: https://doi.org/10.1124/mol.115.103192

Articles

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Quantitative Single-Cell Analysis of Signaling Pathways Activated Immediately Downstream of Histamine Receptor Subtypes
Jakobus van Unen, Ali Rashidfarrokhi, Eelco Hoogendoorn, Marten Postma, Theodorus W. J. Gadella and Joachim Goedhart

Molecular Pharmacology September 2016, 90 (3) 162-176; DOI: https://doi.org/10.1124/mol.116.104505
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Characterization of a Novel M₁ Muscarinic Acetylcholine Receptor Positive Allosteric Modulator Radioligand, [³H]PT-1284
Deborah L. Smith, Jennifer E. Davoren, Jeremy R. Edgerton, John T. Lazzaro, Che-Wah Lee, Sarah Neal, Lei Zhang and Sarah Grimwood

Molecular Pharmacology September 2016, 90 (3) 177-187; DOI: https://doi.org/10.1124/mol.116.104737
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Pharmacological Characterization of the Spectrum of Antiviral Activity and Genetic Barrier to Drug Resistance of M2-S31N Channel Blockers
Chunlong Ma, Jiantao Zhang and Jun Wang

Molecular Pharmacology September 2016, 90 (3) 188-198; DOI: https://doi.org/10.1124/mol.116.105346
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Involvement of Spinal Angiotensin II System in Streptozotocin-Induced Diabetic Neuropathic Pain in Mice
Yoshiki Ogata, Wataru Nemoto, Osamu Nakagawasai, Ryota Yamagata, Takeshi Tadano and Koichi Tan-No

Molecular Pharmacology September 2016, 90 (3) 205-213; DOI: https://doi.org/10.1124/mol.116.104133
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Dihydromunduletone Is a Small-Molecule Selective Adhesion G Protein–Coupled Receptor Antagonist
Hannah M. Stoveken, Laura L. Bahr, M. W. Anders, Andrew P. Wojtovich, Alan V. Smrcka and Gregory G. Tall

Molecular Pharmacology September 2016, 90 (3) 214-224; DOI: https://doi.org/10.1124/mol.116.104828
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Hybrid Enzalutamide Derivatives with Histone Deacetylase Inhibitor Activity Decrease Heat Shock Protein 90 and Androgen Receptor Levels and Inhibit Viability in Enzalutamide-Resistant C4-2 Prostate Cancer Cells
Rayna Rosati, Bailing Chen, Mugdha Patki, Thomas McFall, Siyu Ou, Elisabeth Heath, Manohar Ratnam and Zhihui Qin

Molecular Pharmacology September 2016, 90 (3) 225-237; DOI: https://doi.org/10.1124/mol.116.103416
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Aberrant Subcellular Dynamics of Sigma-1 Receptor Mutants Underlying Neuromuscular Diseases
Adrian Y. C. Wong, Elitza Hristova, Nina Ahlskog, Louis-Alexandre Tasse, Johnny K. Ngsee, Prakash Chudalayandi and Richard Bergeron

Molecular Pharmacology September 2016, 90 (3) 238-253; DOI: https://doi.org/10.1124/mol.116.104018
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Lack of Influence of Substrate on Ligand Interaction with the Human Multidrug and Toxin Extruder, MATE1
Lucy J. Martínez-Guerrero, Mark Morales, Sean Ekins and Stephen H. Wright

Molecular Pharmacology September 2016, 90 (3) 254-264; DOI: https://doi.org/10.1124/mol.116.105056
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Induction of the UDP-Glucuronosyltransferase 1A1 during the Perinatal Period Can Cause Neurodevelopmental Toxicity
Rika Hirashima, Hirofumi Michimae, Hiroaki Takemoto, Aya Sasaki, Yoshinori Kobayashi, Tomoo Itoh, Robert H. Tukey and Ryoichi Fujiwara

Molecular Pharmacology September 2016, 90 (3) 265-274; DOI: https://doi.org/10.1124/mol.116.104174
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Synergistic Potentiation of Cystic Fibrosis Transmembrane Conductance Regulator Gating by Two Chemically Distinct Potentiators, Ivacaftor (VX-770) and 5-Nitro-2-(3-Phenylpropylamino) Benzoate
Wen-Ying Lin, Yoshiro Sohma and Tzyh-Chang Hwang

Molecular Pharmacology September 2016, 90 (3) 275-285; DOI: https://doi.org/10.1124/mol.116.104570

Notice of Retraction

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Re: Abkhezr M and Dryer SE (2014) Angiotensin II and Canonical Transient Receptor Potential-6 Activation Stimulate Release of a Signal Transducer and Activator of Transcription 3–Activating Factor from Mouse Podocytes Mol Pharmacol August 2014 86:150–158; doi:10.1124/mol.114.092536
Molecular Pharmacology September 2016, 90 (3) 160; DOI: https://doi.org/10.1124/mol.114.092536retraction
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Re: Abkhezr M and Dryer SE (2015) STAT3 Regulates Steady-State Expression of Synaptopodin in Cultured Mouse Podocytes Mol Pharmacol February 2015 87:231–239; doi:10.1124/mol.114.094508
Molecular Pharmacology September 2016, 90 (3) 161; DOI: https://doi.org/10.1124/mol.115.094508retraction

Errata

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Correction to “α7β2 Nicotinic Acetylcholine Receptors Assemble, Function, and Are Activated Primarily via Their α7-α7 Interfaces”
Molecular Pharmacology September 2016, 90 (3) 410; DOI: https://doi.org/10.1124/mol.111.074088err
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Correction to: Biological Characterization of an Improved Pyrrole-Based Colchicine Site Agent Identified Through Structure-based Design
Molecular Pharmacology September 2016, 90 (3) 411-412; DOI: https://doi.org/10.1124/mol.115.101592err
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Correction to “Quantitative Single-Cell Analysis of Signaling Pathways Activated Immediately Downstream of Histamine Receptor Subtypes”
Molecular Pharmacology September 2016, 90 (3) 413; DOI: https://doi.org/10.1124/mol.111.104505err

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