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Molecular Pharmacology

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Research ArticleArticle

Lack of Influence of Substrate on Ligand Interaction with the Human Multidrug and Toxin Extruder, MATE1

Lucy J. Martínez-Guerrero, Mark Morales, Sean Ekins and Stephen H. Wright
Molecular Pharmacology September 2016, 90 (3) 254-264; DOI: https://doi.org/10.1124/mol.116.105056
Lucy J. Martínez-Guerrero
Department of Physiology, College of Medicine, University of Arizona, Tucson, Arizona (L.J.M.-G., M.M., S.H.W.); and Collaborations in Chemistry, Fuquay-Varina, North Carolina (S.E.)
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Mark Morales
Department of Physiology, College of Medicine, University of Arizona, Tucson, Arizona (L.J.M.-G., M.M., S.H.W.); and Collaborations in Chemistry, Fuquay-Varina, North Carolina (S.E.)
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Sean Ekins
Department of Physiology, College of Medicine, University of Arizona, Tucson, Arizona (L.J.M.-G., M.M., S.H.W.); and Collaborations in Chemistry, Fuquay-Varina, North Carolina (S.E.)
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Stephen H. Wright
Department of Physiology, College of Medicine, University of Arizona, Tucson, Arizona (L.J.M.-G., M.M., S.H.W.); and Collaborations in Chemistry, Fuquay-Varina, North Carolina (S.E.)
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Article Information

vol. 90 no. 3 254-264
DOI 
https://doi.org/10.1124/mol.116.105056
PubMed 
27418674

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received May 13, 2016
  • Accepted June 30, 2016
  • Published online August 11, 2016.

Article Versions

  • Earlier version (July 14, 2016 - 07:01).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2016 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Lucy J. Martínez-Guerrero,
  2. Mark Morales,
  3. Sean Ekins, and
  4. Stephen H. Wright
  1. Department of Physiology, College of Medicine, University of Arizona, Tucson, Arizona (L.J.M.-G., M.M., S.H.W.); and Collaborations in Chemistry, Fuquay-Varina, North Carolina (S.E.)
  1. Address correspondence to:
    Dr. Stephen H. Wright, Department of Physiology, University of Arizona, Tucson, AZ 85724. E-mail; shwright{at}u.arizona.edu
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Molecular Pharmacology: 90 (3)
Molecular Pharmacology
Vol. 90, Issue 3
1 Sep 2016
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Research ArticleArticle

Substrate Independence of MATE1 Inhibition

Lucy J. Martínez-Guerrero, Mark Morales, Sean Ekins and Stephen H. Wright
Molecular Pharmacology September 1, 2016, 90 (3) 254-264; DOI: https://doi.org/10.1124/mol.116.105056

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Research ArticleArticle

Substrate Independence of MATE1 Inhibition

Lucy J. Martínez-Guerrero, Mark Morales, Sean Ekins and Stephen H. Wright
Molecular Pharmacology September 1, 2016, 90 (3) 254-264; DOI: https://doi.org/10.1124/mol.116.105056
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