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Molecular Pharmacology

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Table of Contents

December 01, 2016; Volume 90,Issue 6

Minireviews

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    For Better or Worse: FFAR1 and FFAR4 Signaling in Cancer and Diabetes
    J. M. Houthuijzen
    Molecular Pharmacology December 2016, 90 (6) 738-743; DOI: https://doi.org/10.1124/mol.116.105932
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    The 2016 John J. Abel Award Lecture: Targeting the Mechanical Microenvironment in Cancer
    Hannah E. Majeski and Jing Yang
    Molecular Pharmacology December 2016, 90 (6) 744-754; DOI: https://doi.org/10.1124/mol.116.106765

Articles

  • GluN2D-Containing N-methyl-<span class="sc">d</span>-Aspartate Receptors Mediate Synaptic Transmission in Hippocampal Interneurons and Regulate Interneuron Activity
    You have access
    GluN2D-Containing N-methyl-d-Aspartate Receptors Mediate Synaptic Transmission in Hippocampal Interneurons and Regulate Interneuron Activity
    Riley E. Perszyk, John O. DiRaddo, Katie L. Strong, Chian-Ming Low, Kevin K. Ogden, Alpa Khatri, Geoffrey A. Vargish, Kenneth A. Pelkey, Ludovic Tricoire, Dennis C. Liotta, Yoland Smith, Chris J. McBain and Stephen F. Traynelis
    Molecular Pharmacology December 2016, 90 (6) 689-702; DOI: https://doi.org/10.1124/mol.116.105130
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    Extracellular Loop 2 of the Adenosine A1 Receptor Has a Key Role in Orthosteric Ligand Affinity and Agonist Efficacy
    Anh T.N. Nguyen, Jo-Anne Baltos, Trayder Thomas, Toan D. Nguyen, Laura López Muñoz, Karen J. Gregory, Paul J. White, Patrick M. Sexton, Arthur Christopoulos and Lauren T. May
    Molecular Pharmacology December 2016, 90 (6) 703-714; DOI: https://doi.org/10.1124/mol.116.105007
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    Role of the Second Extracellular Loop of the Adenosine A1 Receptor on Allosteric Modulator Binding, Signaling, and Cooperativity
    Anh T. N. Nguyen, Elizabeth A. Vecchio, Trayder Thomas, Toan D. Nguyen, Luigi Aurelio, Peter J. Scammells, Paul J. White, Patrick M. Sexton, Karen J. Gregory, Lauren T. May and Arthur Christopoulos
    Molecular Pharmacology December 2016, 90 (6) 715-725; DOI: https://doi.org/10.1124/mol.116.105015
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    Discovery and Characterization of Novel GPR39 Agonists Allosterically Modulated by Zinc
    Seiji Sato, Xi-Ping Huang, Wesley K. Kroeze and Bryan L. Roth
    Molecular Pharmacology December 2016, 90 (6) 726-737; DOI: https://doi.org/10.1124/mol.116.106112
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    Molecular Basis for Inhibition of the Na+/Citrate Transporter NaCT (SLC13A5) by Dicarboxylate Inhibitors
    Ana M. Pajor, Cesar A. de Oliveira, Kun Song, Kim Huard, Veerabahu Shanmugasundaram and Derek M. Erion
    Molecular Pharmacology December 2016, 90 (6) 755-765; DOI: https://doi.org/10.1124/mol.116.105049
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    State-Dependent Allosteric Inhibition of the Human SLC13A5 Citrate Transporter by Hydroxysuccinic Acids, PF-06649298 and PF-06761281
    Marie-Laure Rives, Morena Shaw, Bin Zhu, Simon A. Hinke and Alan D. Wickenden
    Molecular Pharmacology December 2016, 90 (6) 766-774; DOI: https://doi.org/10.1124/mol.116.106575
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In this issue

Molecular Pharmacology: 90 (6)
Molecular Pharmacology
Vol. 90, Issue 6
1 Dec 2016
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  • SB-431542 Is a Potent and Specific Inhibitor of Transforming Growth Factor-β Superfamily Type I Activin Receptor-Like Kinase (ALK) Receptors ALK4, ALK5, and ALK7
  • The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints
  • Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases
  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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