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Supplemental Figure 1 - The structures of the ligands investigated in this study
Supplemental Figure 2 - Example concentration-response curves measured using the GloSensor cAMP assay in CHO-A2A cells...
Supplemental Figure 3 - Control experiments verifying the GloSensor reversal assay to estimate agonist off-rate
Supplemental Figure 4 - Compound 3ce is unique amongst the ligands tested in its ability to discriminate between antagonists in reversal experiments...
Supplemental Figure 5 - Control experiments supporting 3HZM-241385 binding data
Supplemental Figure 6 - Concentration-response curves of agonists in CHO-A2B cells measured using the endpoint cAMP assay
Supplemental Figure 7 - Concentration-response curves of A2A agonists in SH-SY5Y cells measured using the endpoint cAMP assay
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