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Molecular Pharmacology

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Research ArticleArticle
Open Access

Myeloperoxidase Enhances Etoposide and Mitoxantrone-Mediated DNA Damage: A Target for Myeloprotection in Cancer Chemotherapy

Mandeep Atwal, Emma L. Lishman, Caroline A. Austin and Ian G. Cowell
Molecular Pharmacology January 2017, 91 (1) 49-57; DOI: https://doi.org/10.1124/mol.116.106054
Mandeep Atwal
Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle upon Tyne. United Kingdom
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Emma L. Lishman
Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle upon Tyne. United Kingdom
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Caroline A. Austin
Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle upon Tyne. United Kingdom
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Ian G. Cowell
Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle upon Tyne. United Kingdom
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Article Information

vol. 91 no. 1 49-57
DOI 
https://doi.org/10.1124/mol.116.106054
PubMed 
27974636

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received July 8, 2016
  • Accepted November 8, 2016
  • Published online December 14, 2016.

Article Versions

  • Earlier version (November 10, 2016 - 08:30).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2016 The Author(s). This is an open access article distributed under the CC BY Attribution 4.0 International license.

Author Information

  1. Mandeep Atwal,
  2. Emma L. Lishman,
  3. Caroline A. Austin, and
  4. Ian G. Cowell
  1. Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle upon Tyne. United Kingdom
  1. Address correspondence to:
    Dr. Ian G. Cowell, Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle upon Tyne, NE2 4HH United Kingdom. E-mail: Ian.cowell{at}ncl.ac.uk
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Molecular Pharmacology: 91 (1)
Molecular Pharmacology
Vol. 91, Issue 1
1 Jan 2017
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Research ArticleArticle

MPO Increases TOP2 Poison-Mediated DNA Damage

Mandeep Atwal, Emma L. Lishman, Caroline A. Austin and Ian G. Cowell
Molecular Pharmacology January 1, 2017, 91 (1) 49-57; DOI: https://doi.org/10.1124/mol.116.106054

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Research ArticleArticle

MPO Increases TOP2 Poison-Mediated DNA Damage

Mandeep Atwal, Emma L. Lishman, Caroline A. Austin and Ian G. Cowell
Molecular Pharmacology January 1, 2017, 91 (1) 49-57; DOI: https://doi.org/10.1124/mol.116.106054
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