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Molecular Pharmacology

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Table of Contents

July 01, 2017; Volume 92,Issue 1

Mini Special Section—Structural Basis of Receptor-Ligand Interactions

  • You have access
    Structure and Dynamics of the Liver Receptor Homolog 1–PGC1α Complex
    Suzanne G. Mays, C. Denise Okafor, Micheal L. Tuntland, Richard J. Whitby, Venkatasubramanian Dharmarajan, Józef Stec, Patrick R. Griffin and Eric A. Ortlund
    Molecular Pharmacology July 2017, 92 (1) 1-11; DOI: https://doi.org/10.1124/mol.117.108514
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    Structural Analysis of the Glucocorticoid Receptor Ligand-Binding Domain in Complex with Triamcinolone Acetonide and a Fragment of the Atypical Coregulator, Small Heterodimer Partner
    Emily R. Weikum, C. Denise Okafor, Emma H. D’Agostino, Jennifer K. Colucci and Eric A. Ortlund
    Molecular Pharmacology July 2017, 92 (1) 12-21; DOI: https://doi.org/10.1124/mol.117.108506
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    Novel Mode of Antagonist Binding in NMDA Receptors Revealed by the Crystal Structure of the GluN1-GluN2A Ligand-Binding Domain Complexed to NVP-AAM077
    Annabel Romero-Hernandez and Hiro Furukawa
    Molecular Pharmacology July 2017, 92 (1) 22-29; DOI: https://doi.org/10.1124/mol.116.107912

Articles

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    Up-regulated Ectonucleotidases in Fas-Associated Death Domain Protein– and Receptor-Interacting Protein Kinase 1–Deficient Jurkat Leukemia Cells Counteract Extracellular ATP/AMP Accumulation via Pannexin-1 Channels during Chemotherapeutic Drug-Induced Apoptosis
    Andrea M. Boyd-Tressler, Graham S. Lane and George R. Dubyak
    Molecular Pharmacology July 2017, 92 (1) 30-47; DOI: https://doi.org/10.1124/mol.116.104000
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    Negative Regulation of Human Pregnane X Receptor by MicroRNA-18a-5p: Evidence for Suppression of MicroRNA-18a-5p Expression by Rifampin and Rilpivirine
    Devinder Sharma, Abdullah A. Turkistani, Wenjun Chang, Catherine Hu, Zhaoming Xu and Thomas K. H. Chang
    Molecular Pharmacology July 2017, 92 (1) 48-56; DOI: https://doi.org/10.1124/mol.116.107003
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    Dexamethasone Downregulates Endothelin Receptors and Reduces Endothelin-Induced Production of Matrix Metalloproteinases in Cultured Rat Astrocytes
    Yutaka Koyama, Ayano Ukita, Kana Abe, Kuniaki Iwamae, Shogo Tokuyama, Keisuke Tanaka and Yuki Kotake
    Molecular Pharmacology July 2017, 92 (1) 57-66; DOI: https://doi.org/10.1124/mol.116.107300
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    A Glutamate-Substituted Mutant Mimics the Phosphorylated and Active Form of Guanylyl Cyclase-A
    Neil M. Otto, William G. McDowell, Deborah M. Dickey and Lincoln R. Potter
    Molecular Pharmacology July 2017, 92 (1) 67-74; DOI: https://doi.org/10.1124/mol.116.107995
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    Molecular Basis of Metabolism-Mediated Conversion of PK11195 from an Antagonist to an Agonist of the Constitutive Androstane Receptor
    Bryan Mackowiak, Linhao Li, Matthew A. Welch, Daochuan Li, Jace W. Jones, Scott Heyward, Maureen A. Kane, Peter W. Swaan and Hongbing Wang
    Molecular Pharmacology July 2017, 92 (1) 75-87; DOI: https://doi.org/10.1124/mol.117.108621
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    Rapid Throughput Analysis of GABAA Receptor Subtype Modulators and Blockers Using DiSBAC1(3) Membrane Potential Red Dye
    Atefeh Mousavi Nik, Brandon Pressly, Vikrant Singh, Shane Antrobus, Susan Hulsizer, Michael A. Rogawski, Heike Wulff and Isaac N. Pessah
    Molecular Pharmacology July 2017, 92 (1) 88-99; DOI: https://doi.org/10.1124/mol.117.108563

Erratum

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    Correction to “The Orphan Receptor GPR17 Is Unresponsive to Uracil Nucleotides and Cysteinyl Leukotrienes”
    Molecular Pharmacology July 2017, 92 (1) 100; DOI: https://doi.org/10.1124/mol.116.107904err
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In this issue

Molecular Pharmacology: 92 (1)
Molecular Pharmacology
Vol. 92, Issue 1
1 Jul 2017
  • Table of Contents
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  • Mini Special Section—Structural Basis of Receptor-Ligand Interactions
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  • SB-431542 Is a Potent and Specific Inhibitor of Transforming Growth Factor-β Superfamily Type I Activin Receptor-Like Kinase (ALK) Receptors ALK4, ALK5, and ALK7
  • The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints
  • Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases
  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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