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Research ArticleMini Special Section—Structural Basis of Receptor-Ligand Interactions

Novel Mode of Antagonist Binding in NMDA Receptors Revealed by the Crystal Structure of the GluN1-GluN2A Ligand-Binding Domain Complexed to NVP-AAM077

Annabel Romero-Hernandez and Hiro Furukawa
Molecular Pharmacology July 2017, 92 (1) 22-29; DOI: https://doi.org/10.1124/mol.116.107912

Article Information

vol. 92 no. 1 22-29
DOI 
https://doi.org/10.1124/mol.116.107912
PubMed 
28468946
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received December 15, 2016
  • Accepted May 1, 2017
  • Published online May 26, 2017.

Article Versions

Copyright & Usage 
Copyright © 2017 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Annabel Romero-Hernandez and
  2. Hiro Furukawa
  1. Keck Structural Biology Laboratory, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York (A.R.-H., H.F.); and Watson School of Biological Sciences, Cold Spring Harbor, New York (A.R.-H., H.F.)
  1. Address correspondence to:
    Dr. Hiro Furukawa, One Bungtown Road, Cold Spring Harbor, NY 11724. E-mail: furukawa{at}cshl.edu
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Research ArticleMini Special Section—Structural Basis of Receptor-Ligand Interactions

Crystal Structure of NMDA Receptor Bound to NVP-AAM077

Annabel Romero-Hernandez and Hiro Furukawa
Molecular Pharmacology July 1, 2017, 92 (1) 22-29; DOI: https://doi.org/10.1124/mol.116.107912
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