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Up-regulated Ectonucleotidases in Fas-Associated Death Domain Protein– and Receptor-Interacting Protein Kinase 1–Deficient Jurkat Leukemia Cells Counteract Extracellular ATP/AMP Accumulation via Pannexin-1 Channels during Chemotherapeutic Drug-Induced Apoptosis

Andrea M. Boyd-Tressler, Graham S. Lane and George R. Dubyak
Molecular Pharmacology July 2017, 92 (1) 30-47; DOI: https://doi.org/10.1124/mol.116.104000

Article Information

vol. 92 no. 1 30-47
DOI 
https://doi.org/10.1124/mol.116.104000
PubMed 
28461585
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received February 23, 2016
  • Accepted April 26, 2017
  • Published online May 26, 2017.

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Copyright & Usage 
Copyright © 2017 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Andrea M. Boyd-Tressler,
  2. Graham S. Lane, and
  3. George R. Dubyak
  1. Department of Physiology & Biophysics (G.S.L., G.R.D.), Department of Pharmacology (A.M.B.-T., G.R.D.), and Case Comprehensive Cancer Center (G.R.D.), School of Medicine, Case Western Reserve University, Cleveland, Ohio
  1. Address correspondence to:
    Dr. George R. Dubyak, Department of Physiology & Biophysics, School of Medicine, Case Western Reserve University, 10900 Euclid Avenue, Cleveland OH 44106. E-mail: george.dubyak{at}case.edu
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Ectonucleotidases Modulate Apoptotic ATP/AMP Accumulation

Andrea M. Boyd-Tressler, Graham S. Lane and George R. Dubyak
Molecular Pharmacology July 1, 2017, 92 (1) 30-47; DOI: https://doi.org/10.1124/mol.116.104000
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