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Rapid CommunicationMinireview—Molecular Pharmacology in China

Tumor Microenvironment Targeting and Responsive Peptide-Based Nanoformulations for Improved Tumor Therapy

Hao Qin, Yanping Ding, Ayeesha Mujeeb, Ying Zhao and Guangjun Nie
Molecular Pharmacology September 2017, 92 (3) 219-231; DOI: https://doi.org/10.1124/mol.116.108084
Hao Qin
CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety and CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology (H.Q., Y D., A.M., Y. Z., G.N.), and University of Chinese Academy of Sciences (H.Q., Y.D., Y.Z., G.N.), Beijing, China
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Yanping Ding
CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety and CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology (H.Q., Y D., A.M., Y. Z., G.N.), and University of Chinese Academy of Sciences (H.Q., Y.D., Y.Z., G.N.), Beijing, China
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Ayeesha Mujeeb
CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety and CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology (H.Q., Y D., A.M., Y. Z., G.N.), and University of Chinese Academy of Sciences (H.Q., Y.D., Y.Z., G.N.), Beijing, China
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Ying Zhao
CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety and CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology (H.Q., Y D., A.M., Y. Z., G.N.), and University of Chinese Academy of Sciences (H.Q., Y.D., Y.Z., G.N.), Beijing, China
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Guangjun Nie
CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety and CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology (H.Q., Y D., A.M., Y. Z., G.N.), and University of Chinese Academy of Sciences (H.Q., Y.D., Y.Z., G.N.), Beijing, China
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Article Information

vol. 92 no. 3 219-231
DOI 
https://doi.org/10.1124/mol.116.108084
PubMed 
28420679

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received January 3, 2017
  • Accepted April 12, 2017
  • Published online August 1, 2017.

Article Versions

  • Earlier version (April 18, 2017 - 07:15).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2017 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Hao Qin,
  2. Yanping Ding,
  3. Ayeesha Mujeeb,
  4. Ying Zhao, and
  5. Guangjun Nie
  1. CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety and CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology (H.Q., Y D., A.M., Y. Z., G.N.), and University of Chinese Academy of Sciences (H.Q., Y.D., Y.Z., G.N.), Beijing, China
  1. Address correspondence to:
    Prof. Guangjun Nie, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety & CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, No. 11 Beiyitiao, Zhongguancun, Beijing 100190, China. E-mail: niegi{at}nanoctr.cn or Prof. Ying Zhao, University of Chinese Academy of Sciences, Beijing 100049, China. E-mail: zhaoying{at}nanoctr.cn
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Molecular Pharmacology: 92 (3)
Molecular Pharmacology
Vol. 92, Issue 3
1 Sep 2017
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Rapid CommunicationMinireview—Molecular Pharmacology in China

Peptide Nanoformulations against the Tumor Microenvironment

Hao Qin, Yanping Ding, Ayeesha Mujeeb, Ying Zhao and Guangjun Nie
Molecular Pharmacology September 1, 2017, 92 (3) 219-231; DOI: https://doi.org/10.1124/mol.116.108084

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Rapid CommunicationMinireview—Molecular Pharmacology in China

Peptide Nanoformulations against the Tumor Microenvironment

Hao Qin, Yanping Ding, Ayeesha Mujeeb, Ying Zhao and Guangjun Nie
Molecular Pharmacology September 1, 2017, 92 (3) 219-231; DOI: https://doi.org/10.1124/mol.116.108084
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  • Article
    • Abstract
    • Introduction
    • Functional Peptides
    • Tumor Microenvironment Targeting and Responsive Peptide-Based Nanoformulations
    • Ligand Peptides Mediate Nanoformulations to Target Tumor Microenvironment
    • Enhanced Tumor Penetration via Tumor Microenvironment Responsive Peptides
    • Peptide Self-Assembled Nanoformulations Targeting CAFs to Break Stromal Barriers
    • Therapeutic Peptide Self-Assembled Nanoformulations Targeting Tumor Vasculatures
    • Conclusions
    • Authorship Contributions
    • Footnotes
    • Abbreviations
    • References
  • Figures & Data
  • Info & Metrics
  • eLetters
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