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Molecular Pharmacology

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Table of Contents

December 01, 2017; Volume 92,Issue 6

Minireview

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    Notch Signaling: Linking Embryonic Lung Development and Asthmatic Airway Remodeling
    Musaddique Hussain, Chengyun Xu, Mashaal Ahmad, Youping Yang, Meiping Lu, Xiling Wu, Lanfang Tang and Ximei Wu
    Molecular Pharmacology December 2017, 92 (6) 676-693; DOI: https://doi.org/10.1124/mol.117.110254

Articles

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    Effective Attenuation of Adenosine A1R Signaling by Neurabin Requires Oligomerization of Neurabin
    Yunjia Chen, Christopher Booth, Hongxia Wang, Raymond X. Wang, Dimitra Terzi, Venetia Zachariou, Kai Jiao, Jin Zhang and Qin Wang
    Molecular Pharmacology December 2017, 92 (6) 630-639; DOI: https://doi.org/10.1124/mol.117.109462
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    Activation of AMPK/mTORC1-Mediated Autophagy by Metformin Reverses Clk1 Deficiency-Sensitized Dopaminergic Neuronal Death
    Qiuting Yan, Chaojun Han, Guanghui Wang, John L. Waddington, Longtai Zheng and Xuechu Zhen
    Molecular Pharmacology December 2017, 92 (6) 640-652; DOI: https://doi.org/10.1124/mol.117.109512
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    Activation of Human Transient Receptor Potential Melastatin-8 (TRPM8) by Calcium-Rich Particulate Materials and Effects on Human Lung Cells
    John G. Lamb, Erin G. Romero, Zhenyu Lu, Seychelle K. Marcus, Hannah C. Peterson, John M. Veranth, Cassandra E. Deering-Rice and Christopher A. Reilly
    Molecular Pharmacology December 2017, 92 (6) 653-664; DOI: https://doi.org/10.1124/mol.117.109959
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    Diminazene Is a Slow Pore Blocker of Acid-Sensing Ion Channel 1a (ASIC1a)
    Axel Schmidt, Giulia Rossetti, Sylvia Joussen and Stefan Gründer
    Molecular Pharmacology December 2017, 92 (6) 665-675; DOI: https://doi.org/10.1124/mol.117.110064
  • Open Access
    RVX-297, a BET Bromodomain Inhibitor, Has Therapeutic Effects in Preclinical Models of Acute Inflammation and Autoimmune Disease
    Ravi Jahagirdar, Sarah Attwell, Suzana Marusic, Alison Bendele, Narmada Shenoy, Kevin G. McLure, Dean Gilham, Karen Norek, Henrik C. Hansen, Raymond Yu, Jennifer Tobin, Gregory S. Wagner, Peter R. Young, Norman C. W. Wong and Ewelina Kulikowski
    Molecular Pharmacology December 2017, 92 (6) 694-706; DOI: https://doi.org/10.1124/mol.117.110379
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    Structural Determinants Influencing the Potency and Selectivity of Indazole-Paroxetine Hybrid G Protein–Coupled Receptor Kinase 2 Inhibitors
    Renee Bouley, Helen V. Waldschmidt, M. Claire Cato, Alessandro Cannavo, Jianliang Song, Joseph Y. Cheung, Xin-Qiu Yao, Walter J. Koch, Scott D. Larsen and John J. G. Tesmer
    Molecular Pharmacology December 2017, 92 (6) 707-717; DOI: https://doi.org/10.1124/mol.117.110130
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    Hydrogen Sulfide Preserves Endothelial Nitric Oxide Synthase Function by Inhibiting Proline-Rich Kinase 2: Implications for Cardiomyocyte Survival and Cardioprotection
    Sofia-Iris Bibli, Csaba Szabo, Athanasia Chatzianastasiou, Bert Luck, Sven Zukunft, Ingrid Fleming and Andreas Papapetropoulos
    Molecular Pharmacology December 2017, 92 (6) 718-730; DOI: https://doi.org/10.1124/mol.117.109645

Errata

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    Correction to “Novel Small Molecule JP-153 Targets the Src-FAK-Paxillin Signaling Complex to Inhibit VEGF-Induced Retinal Angiogenesis”
    Molecular Pharmacology December 2017, 92 (6) 627; DOI: https://doi.org/10.1124/mol.116.105031err
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    Correction to “G-Protein–Coupled Receptor Kinase 2 as a Potential Modulator of the Hallmarks of Cancer”
    Molecular Pharmacology December 2017, 92 (6) 628; DOI: https://doi.org/10.1124/mol.116.107185err
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    Correction to “The Emerging Role of Cable1 in Cancer and Other Diseases”
    Molecular Pharmacology December 2017, 92 (6) 629; DOI: https://doi.org/10.1124/mol.116.107730err
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In this issue

Molecular Pharmacology: 92 (6)
Molecular Pharmacology
Vol. 92, Issue 6
1 Dec 2017
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  • SB-431542 Is a Potent and Specific Inhibitor of Transforming Growth Factor-β Superfamily Type I Activin Receptor-Like Kinase (ALK) Receptors ALK4, ALK5, and ALK7
  • The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints
  • Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases
  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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