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Molecular Pharmacology

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Table of Contents

February 01, 2018; Volume 93,Issue 2

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    PXR: More Than Just a Master Xenobiotic Receptor
    Peter O. Oladimeji and Taosheng Chen
    Molecular Pharmacology February 2018, 93 (2) 119-127; DOI: https://doi.org/10.1124/mol.117.110155

Articles

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    ABIN-1 Negatively Regulates μ-Opioid Receptor Function
    Peilan Zhou, Jiebing Jiang, Hui Yan, Yulei Li, Junru Zhao, Xiao Wang, Ruibin Su and Zehui Gong
    Molecular Pharmacology February 2018, 93 (2) 36-48; DOI: https://doi.org/10.1124/mol.117.109009
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    Slowly Signaling G Protein–Biased CB2 Cannabinoid Receptor Agonist LY2828360 Suppresses Neuropathic Pain with Sustained Efficacy and Attenuates Morphine Tolerance and Dependence
    Xiaoyan Lin, Amey S. Dhopeshwarkar, Megan Huibregtse, Ken Mackie and Andrea G. Hohmann
    Molecular Pharmacology February 2018, 93 (2) 49-62; DOI: https://doi.org/10.1124/mol.117.109355
  • Identification of an Oleanane-Type Triterpene Hedragonic Acid as a Novel Farnesoid X Receptor Ligand with Liver Protective Effects and Anti-inflammatory Activity
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    Identification of an Oleanane-Type Triterpene Hedragonic Acid as a Novel Farnesoid X Receptor Ligand with Liver Protective Effects and Anti-inflammatory Activity
    Yi Lu, Weili Zheng, Shengchen Lin, Fusheng Guo, Yanlin Zhu, Yijuan Wei, Xi Liu, Shikai Jin, Lihua Jin and Yong Li
    Molecular Pharmacology February 2018, 93 (2) 63-72; DOI: https://doi.org/10.1124/mol.117.109900
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    Irreversible Activation and Stabilization of Soluble Guanylate Cyclase by the Protoporphyrin IX Mimetic Cinaciguat
    Alexander Kollau, Marissa Opelt, Gerald Wölkart, Antonius C. F. Gorren, Michael Russwurm, Doris Koesling, Bernd Mayer and Astrid Schrammel
    Molecular Pharmacology February 2018, 93 (2) 73-78; DOI: https://doi.org/10.1124/mol.117.109918
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    Molecular Imaging of GLUT1 and GLUT5 in Breast Cancer: A Multitracer Positron Emission Tomography Imaging Study in Mice
    Melinda Wuest, Ingrit Hamann, Vincent Bouvet, Darryl Glubrecht, Alison Marshall, Brendan Trayner, Olivier-Mohamad Soueidan, Daniel Krys, Michael Wagner, Chris Cheeseman, Frederick West and Frank Wuest
    Molecular Pharmacology February 2018, 93 (2) 79-89; DOI: https://doi.org/10.1124/mol.117.110007
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    GABA Type A Receptor Activation in the Allosteric Coagonist Model Framework: Relationship between EC50 and Basal Activity
    Gustav Akk, Daniel J. Shin, Allison L. Germann and Joe Henry Steinbach
    Molecular Pharmacology February 2018, 93 (2) 90-100; DOI: https://doi.org/10.1124/mol.117.110569
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    Drugs and Scaffold That Inhibit Cytochrome P450 27A1 In Vitro and In Vivo
    Morrie Lam, Natalia Mast and Irina A. Pikuleva
    Molecular Pharmacology February 2018, 93 (2) 101-108; DOI: https://doi.org/10.1124/mol.117.110742
  • Open Access
    S1P1 Modulator-Induced Gαi Signaling and β-Arrestin Recruitment Are Both Necessary to Induce Rapid and Efficient Reduction of Blood Lymphocyte Count In Vivo
    Magdalena Birker-Robaczewska, Martin Bolli, Markus Rey, Ruben de Kanter, Christopher Kohl, Cyrille Lescop, Maxime Boucher, Sylvie Poirey, Beat Steiner and Oliver Nayler
    Molecular Pharmacology February 2018, 93 (2) 109-118; DOI: https://doi.org/10.1124/mol.117.109140
  • Open Access
    Diversity of Nicotinic Acetylcholine Receptor Positive Allosteric Modulators Revealed by Mutagenesis and a Revised Structural Model
    Joseph Newcombe, Anna Chatzidaki, Tom D. Sheppard, Maya Topf and Neil S. Millar
    Molecular Pharmacology February 2018, 93 (2) 128-140; DOI: https://doi.org/10.1124/mol.117.110551
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    The Bioactive Protein-Ligand Conformation of GluN2C-Selective Positive Allosteric Modulators Bound to the NMDA Receptor
    Thomas M. Kaiser, Steven A. Kell, Hirofumi Kusumoto, Gil Shaulsky, Subhrajit Bhattacharya, Matthew P. Epplin, Katie L. Strong, Eric J. Miller, Bryan D. Cox, David S. Menaldino, Dennis C. Liotta, Stephen F. Traynelis and Pieter B. Burger
    Molecular Pharmacology February 2018, 93 (2) 141-156; DOI: https://doi.org/10.1124/mol.117.110940
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    Pharmacologic Evidence for a Putative Conserved Allosteric Site on Opioid Receptors
    Kathryn E. Livingston, M. Alexander Stanczyk, Neil T. Burford, Andrew Alt, Meritxell Canals and John R. Traynor
    Molecular Pharmacology February 2018, 93 (2) 157-167; DOI: https://doi.org/10.1124/mol.117.109561
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    (Z)-2-(3,4-Dichlorophenyl)-3-(1H-Pyrrol-2-yl)Acrylonitrile Exhibits Selective Antitumor Activity in Breast Cancer Cell Lines via the Aryl Hydrocarbon Receptor Pathway
    Jayne Gilbert, Geoffry N. De Iuliis, Mark Tarleton, Adam McCluskey and Jennette A. Sakoff
    Molecular Pharmacology February 2018, 93 (2) 168-177; DOI: https://doi.org/10.1124/mol.117.109827
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    Propofol Is an Allosteric Agonist with Multiple Binding Sites on Concatemeric Ternary GABAA Receptors
    Daniel J. Shin, Allison L. Germann, Alexander D. Johnson, Stuart A. Forman, Joe Henry Steinbach and Gustav Akk
    Molecular Pharmacology February 2018, 93 (2) 178-189; DOI: https://doi.org/10.1124/mol.117.110403
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Molecular Pharmacology: 93 (2)
Molecular Pharmacology
Vol. 93, Issue 2
1 Feb 2018
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