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Molecular Pharmacology

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Index by author

April 01, 2018; Volume 93,Issue 4
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Abrie, J. Albert

    1. Open Access
      Investigation into the Mechanism of Homo- and Heterodimerization of Angiotensin-Converting Enzyme
      J. Albert Abrie, Wessel J. A. Moolman, Gyles E. Cozier, Sylva L. Schwager, K. Ravi Acharya and Edward D. Sturrock
      Molecular Pharmacology April 2018, 93 (4) 344-354; DOI: https://doi.org/10.1124/mol.117.110866
  2. Acharya, K. Ravi

    1. Open Access
      Investigation into the Mechanism of Homo- and Heterodimerization of Angiotensin-Converting Enzyme
      J. Albert Abrie, Wessel J. A. Moolman, Gyles E. Cozier, Sylva L. Schwager, K. Ravi Acharya and Edward D. Sturrock
      Molecular Pharmacology April 2018, 93 (4) 344-354; DOI: https://doi.org/10.1124/mol.117.110866
  3. Agarwal, Shailesh R.

    1. You have access
      cAMP Signaling Compartmentation: Adenylyl Cyclases as Anchors of Dynamic Signaling Complexes
      Timothy B. Johnstone, Shailesh R. Agarwal, Robert D. Harvey and Rennolds S. Ostrom
      Molecular Pharmacology April 2018, 93 (4) 270-276; DOI: https://doi.org/10.1124/mol.117.110825
  4. Albert, Christoph M.

    1. You have access
      Assay Conditions Influence Affinities of Rat Organic Cation Transporter 1: Analysis of Mutagenesis in the Modeled Outward-Facing Cleft by Measuring Effects of Substrates and Inhibitors on Initial Uptake
      Valentin Gorboulev, Saba Rehman, Christoph M. Albert, Ursula Roth, Marleen J. Meyer, Mladen V. Tzvetkov, Thomas D. Mueller and Hermann Koepsell
      Molecular Pharmacology April 2018, 93 (4) 402-415; DOI: https://doi.org/10.1124/mol.117.110767
  5. Åqvist, Johan

    1. Open Access
      Elucidation of the Binding Mode of the Carboxyterminal Region of Peptide YY to the Human Y2 Receptor
      Bo Xu, Silvana Vasile, Søren Østergaard, Johan F. Paulsson, Jasna Pruner, Johan Åqvist, Birgitte S. Wulff, Hugo Gutiérrez-de-Terán and Dan Larhammar
      Molecular Pharmacology April 2018, 93 (4) 323-334; DOI: https://doi.org/10.1124/mol.117.110627

B

  1. Bao, Mei-Hua

    1. Long Noncoding RNA LINC00657 Acting as a miR-590-3p Sponge to Facilitate Low Concentration Oxidized Low-Density Lipoprotein–Induced Angiogenesis
      You have access
      Long Noncoding RNA LINC00657 Acting as a miR-590-3p Sponge to Facilitate Low Concentration Oxidized Low-Density Lipoprotein–Induced Angiogenesis
      Mei-Hua Bao, Guang-Yi Li, Xiao-Shan Huang, Liang Tang, Li-Ping Dong and Jian-Ming Li
      Molecular Pharmacology April 2018, 93 (4) 368-375; DOI: https://doi.org/10.1124/mol.117.110650
  2. Baumeister, Paul

    1. You have access
      Molecular Mechanisms of Biased and Probe-Dependent Signaling at CXC-Motif Chemokine Receptor CXCR3 Induced by Negative Allosteric Modulators
      Regine Brox, Lampros Milanos, Noureldin Saleh, Paul Baumeister, Armin Buschauer, Dagmar Hofmann, Markus R. Heinrich, Timothy Clark and Nuska Tschammer
      Molecular Pharmacology April 2018, 93 (4) 309-322; DOI: https://doi.org/10.1124/mol.117.110296
  3. Beck-Sickinger, Annette G.

    1. You have access
      G Protein Preassembly Rescues Efficacy of W6.48 Toggle Mutations in Neuropeptide Y2 Receptor
      Anette Kaiser, Caroline Hempel, Lizzy Wanka, Mario Schubert, Heidi E. Hamm and Annette G. Beck-Sickinger
      Molecular Pharmacology April 2018, 93 (4) 387-401; DOI: https://doi.org/10.1124/mol.117.110544
  4. Berg, Kelly A.

    1. You have access
      Allosterism within δ Opioid–κ Opioid Receptor Heteromers in Peripheral Sensory Neurons: Regulation of κ Opioid Agonist Efficacy
      Blaine A. Jacobs, Miryam M. Pando, Elaine Jennings, Teresa A. Chavera, William P. Clarke and Kelly A. Berg
      Molecular Pharmacology April 2018, 93 (4) 376-386; DOI: https://doi.org/10.1124/mol.117.109975
  5. Bhattacharya, Supriyo

    1. You have access
      Identifying Functional Hotspot Residues for Biased Ligand Design in G-Protein-Coupled Receptors
      Anita K. Nivedha, Christofer S. Tautermann, Supriyo Bhattacharya, Sangbae Lee, Paola Casarosa, Ines Kollak, Tobias Kiechle and Nagarajan Vaidehi
      Molecular Pharmacology April 2018, 93 (4) 288-296; DOI: https://doi.org/10.1124/mol.117.110395
  6. Booe, Jason M.

    1. You have access
      Probing the Mechanism of Receptor Activity–Modifying Protein Modulation of GPCR Ligand Selectivity through Rational Design of Potent Adrenomedullin and Calcitonin Gene-Related Peptide Antagonists
      Jason M. Booe, Margaret L. Warner, Amanda M. Roehrkasse, Debbie L. Hay and Augen A. Pioszak
      Molecular Pharmacology April 2018, 93 (4) 355-367; DOI: https://doi.org/10.1124/mol.117.110916
  7. Brox, Regine

    1. You have access
      Molecular Mechanisms of Biased and Probe-Dependent Signaling at CXC-Motif Chemokine Receptor CXCR3 Induced by Negative Allosteric Modulators
      Regine Brox, Lampros Milanos, Noureldin Saleh, Paul Baumeister, Armin Buschauer, Dagmar Hofmann, Markus R. Heinrich, Timothy Clark and Nuska Tschammer
      Molecular Pharmacology April 2018, 93 (4) 309-322; DOI: https://doi.org/10.1124/mol.117.110296
  8. Buschauer, Armin

    1. You have access
      Molecular Mechanisms of Biased and Probe-Dependent Signaling at CXC-Motif Chemokine Receptor CXCR3 Induced by Negative Allosteric Modulators
      Regine Brox, Lampros Milanos, Noureldin Saleh, Paul Baumeister, Armin Buschauer, Dagmar Hofmann, Markus R. Heinrich, Timothy Clark and Nuska Tschammer
      Molecular Pharmacology April 2018, 93 (4) 309-322; DOI: https://doi.org/10.1124/mol.117.110296

C

  1. Casarosa, Paola

    1. You have access
      Identifying Functional Hotspot Residues for Biased Ligand Design in G-Protein-Coupled Receptors
      Anita K. Nivedha, Christofer S. Tautermann, Supriyo Bhattacharya, Sangbae Lee, Paola Casarosa, Ines Kollak, Tobias Kiechle and Nagarajan Vaidehi
      Molecular Pharmacology April 2018, 93 (4) 288-296; DOI: https://doi.org/10.1124/mol.117.110395
  2. Charlton, Steven J.

    1. You have access
      Biased Agonism in Drug Discovery—Is It Too Soon to Choose a Path?
      Martin C. Michel and Steven J. Charlton
      Molecular Pharmacology April 2018, 93 (4) 259-265; DOI: https://doi.org/10.1124/mol.117.110890
  3. Chavera, Teresa A.

    1. You have access
      Allosterism within δ Opioid–κ Opioid Receptor Heteromers in Peripheral Sensory Neurons: Regulation of κ Opioid Agonist Efficacy
      Blaine A. Jacobs, Miryam M. Pando, Elaine Jennings, Teresa A. Chavera, William P. Clarke and Kelly A. Berg
      Molecular Pharmacology April 2018, 93 (4) 376-386; DOI: https://doi.org/10.1124/mol.117.109975
  4. Clark, Timothy

    1. You have access
      Molecular Mechanisms of Biased and Probe-Dependent Signaling at CXC-Motif Chemokine Receptor CXCR3 Induced by Negative Allosteric Modulators
      Regine Brox, Lampros Milanos, Noureldin Saleh, Paul Baumeister, Armin Buschauer, Dagmar Hofmann, Markus R. Heinrich, Timothy Clark and Nuska Tschammer
      Molecular Pharmacology April 2018, 93 (4) 309-322; DOI: https://doi.org/10.1124/mol.117.110296
  5. Clarke, William P.

    1. You have access
      Allosterism within δ Opioid–κ Opioid Receptor Heteromers in Peripheral Sensory Neurons: Regulation of κ Opioid Agonist Efficacy
      Blaine A. Jacobs, Miryam M. Pando, Elaine Jennings, Teresa A. Chavera, William P. Clarke and Kelly A. Berg
      Molecular Pharmacology April 2018, 93 (4) 376-386; DOI: https://doi.org/10.1124/mol.117.109975
  6. Cozier, Gyles E.

    1. Open Access
      Investigation into the Mechanism of Homo- and Heterodimerization of Angiotensin-Converting Enzyme
      J. Albert Abrie, Wessel J. A. Moolman, Gyles E. Cozier, Sylva L. Schwager, K. Ravi Acharya and Edward D. Sturrock
      Molecular Pharmacology April 2018, 93 (4) 344-354; DOI: https://doi.org/10.1124/mol.117.110866

D

  1. Dong, Li-Ping

    1. Long Noncoding RNA LINC00657 Acting as a miR-590-3p Sponge to Facilitate Low Concentration Oxidized Low-Density Lipoprotein–Induced Angiogenesis
      You have access
      Long Noncoding RNA LINC00657 Acting as a miR-590-3p Sponge to Facilitate Low Concentration Oxidized Low-Density Lipoprotein–Induced Angiogenesis
      Mei-Hua Bao, Guang-Yi Li, Xiao-Shan Huang, Liang Tang, Li-Ping Dong and Jian-Ming Li
      Molecular Pharmacology April 2018, 93 (4) 368-375; DOI: https://doi.org/10.1124/mol.117.110650

E

  1. Eroglu, Emrah

    1. Open Access
      Sustained Formation of Nitroglycerin-Derived Nitric Oxide by Aldehyde Dehydrogenase-2 in Vascular Smooth Muscle without Added Reductants: Implications for the Development of Nitrate Tolerance
      Marissa Opelt, Gerald Wölkart, Emrah Eroglu, Markus Waldeck-Weiermair, Roland Malli, Wolfgang F. Graier, Alexander Kollau, John T. Fassett, Astrid Schrammel, Bernd Mayer and Antonius C. F. Gorren
      Molecular Pharmacology April 2018, 93 (4) 335-343; DOI: https://doi.org/10.1124/mol.117.110783

F

  1. Fassett, John T.

    1. Open Access
      Sustained Formation of Nitroglycerin-Derived Nitric Oxide by Aldehyde Dehydrogenase-2 in Vascular Smooth Muscle without Added Reductants: Implications for the Development of Nitrate Tolerance
      Marissa Opelt, Gerald Wölkart, Emrah Eroglu, Markus Waldeck-Weiermair, Roland Malli, Wolfgang F. Graier, Alexander Kollau, John T. Fassett, Astrid Schrammel, Bernd Mayer and Antonius C. F. Gorren
      Molecular Pharmacology April 2018, 93 (4) 335-343; DOI: https://doi.org/10.1124/mol.117.110783
  2. Fathima, Samreen

    1. Open Access
      Pharmacogenomics of Chemically Distinct Classes of Keap1-Nrf2 Activators Identify Common and Unique Gene, Protein, and Pathway Responses In Vivo
      Ryan S. Wible, Quynh T. Tran, Samreen Fathima, Carrie H. Sutter, Thomas W. Kensler and Thomas R. Sutter
      Molecular Pharmacology April 2018, 93 (4) 297-308; DOI: https://doi.org/10.1124/mol.117.110262

G

  1. Gorboulev, Valentin

    1. You have access
      Assay Conditions Influence Affinities of Rat Organic Cation Transporter 1: Analysis of Mutagenesis in the Modeled Outward-Facing Cleft by Measuring Effects of Substrates and Inhibitors on Initial Uptake
      Valentin Gorboulev, Saba Rehman, Christoph M. Albert, Ursula Roth, Marleen J. Meyer, Mladen V. Tzvetkov, Thomas D. Mueller and Hermann Koepsell
      Molecular Pharmacology April 2018, 93 (4) 402-415; DOI: https://doi.org/10.1124/mol.117.110767
  2. Gorren, Antonius C. F.

    1. Open Access
      Sustained Formation of Nitroglycerin-Derived Nitric Oxide by Aldehyde Dehydrogenase-2 in Vascular Smooth Muscle without Added Reductants: Implications for the Development of Nitrate Tolerance
      Marissa Opelt, Gerald Wölkart, Emrah Eroglu, Markus Waldeck-Weiermair, Roland Malli, Wolfgang F. Graier, Alexander Kollau, John T. Fassett, Astrid Schrammel, Bernd Mayer and Antonius C. F. Gorren
      Molecular Pharmacology April 2018, 93 (4) 335-343; DOI: https://doi.org/10.1124/mol.117.110783
  3. Graier, Wolfgang F.

    1. Open Access
      Sustained Formation of Nitroglycerin-Derived Nitric Oxide by Aldehyde Dehydrogenase-2 in Vascular Smooth Muscle without Added Reductants: Implications for the Development of Nitrate Tolerance
      Marissa Opelt, Gerald Wölkart, Emrah Eroglu, Markus Waldeck-Weiermair, Roland Malli, Wolfgang F. Graier, Alexander Kollau, John T. Fassett, Astrid Schrammel, Bernd Mayer and Antonius C. F. Gorren
      Molecular Pharmacology April 2018, 93 (4) 335-343; DOI: https://doi.org/10.1124/mol.117.110783
  4. Gutiérrez-de-Terán, Hugo

    1. Open Access
      Elucidation of the Binding Mode of the Carboxyterminal Region of Peptide YY to the Human Y2 Receptor
      Bo Xu, Silvana Vasile, Søren Østergaard, Johan F. Paulsson, Jasna Pruner, Johan Åqvist, Birgitte S. Wulff, Hugo Gutiérrez-de-Terán and Dan Larhammar
      Molecular Pharmacology April 2018, 93 (4) 323-334; DOI: https://doi.org/10.1124/mol.117.110627

H

  1. Hamm, Heidi E.

    1. You have access
      G Protein Preassembly Rescues Efficacy of W6.48 Toggle Mutations in Neuropeptide Y2 Receptor
      Anette Kaiser, Caroline Hempel, Lizzy Wanka, Mario Schubert, Heidi E. Hamm and Annette G. Beck-Sickinger
      Molecular Pharmacology April 2018, 93 (4) 387-401; DOI: https://doi.org/10.1124/mol.117.110544
  2. Harvey, Robert D.

    1. You have access
      cAMP Signaling Compartmentation: Adenylyl Cyclases as Anchors of Dynamic Signaling Complexes
      Timothy B. Johnstone, Shailesh R. Agarwal, Robert D. Harvey and Rennolds S. Ostrom
      Molecular Pharmacology April 2018, 93 (4) 270-276; DOI: https://doi.org/10.1124/mol.117.110825
  3. Hay, Debbie L.

    1. You have access
      Probing the Mechanism of Receptor Activity–Modifying Protein Modulation of GPCR Ligand Selectivity through Rational Design of Potent Adrenomedullin and Calcitonin Gene-Related Peptide Antagonists
      Jason M. Booe, Margaret L. Warner, Amanda M. Roehrkasse, Debbie L. Hay and Augen A. Pioszak
      Molecular Pharmacology April 2018, 93 (4) 355-367; DOI: https://doi.org/10.1124/mol.117.110916
  4. Head, Brian P.

    1. You have access
      Caveolins as Regulators of Stress Adaptation
      Jan M. Schilling, Brian P. Head and Hemal H. Patel
      Molecular Pharmacology April 2018, 93 (4) 277-285; DOI: https://doi.org/10.1124/mol.117.111237
  5. Heinrich, Markus R.

    1. You have access
      Molecular Mechanisms of Biased and Probe-Dependent Signaling at CXC-Motif Chemokine Receptor CXCR3 Induced by Negative Allosteric Modulators
      Regine Brox, Lampros Milanos, Noureldin Saleh, Paul Baumeister, Armin Buschauer, Dagmar Hofmann, Markus R. Heinrich, Timothy Clark and Nuska Tschammer
      Molecular Pharmacology April 2018, 93 (4) 309-322; DOI: https://doi.org/10.1124/mol.117.110296
  6. Hempel, Caroline

    1. You have access
      G Protein Preassembly Rescues Efficacy of W6.48 Toggle Mutations in Neuropeptide Y2 Receptor
      Anette Kaiser, Caroline Hempel, Lizzy Wanka, Mario Schubert, Heidi E. Hamm and Annette G. Beck-Sickinger
      Molecular Pharmacology April 2018, 93 (4) 387-401; DOI: https://doi.org/10.1124/mol.117.110544
  7. Hofmann, Dagmar

    1. You have access
      Molecular Mechanisms of Biased and Probe-Dependent Signaling at CXC-Motif Chemokine Receptor CXCR3 Induced by Negative Allosteric Modulators
      Regine Brox, Lampros Milanos, Noureldin Saleh, Paul Baumeister, Armin Buschauer, Dagmar Hofmann, Markus R. Heinrich, Timothy Clark and Nuska Tschammer
      Molecular Pharmacology April 2018, 93 (4) 309-322; DOI: https://doi.org/10.1124/mol.117.110296
  8. Huang, Xiao-Shan

    1. Long Noncoding RNA LINC00657 Acting as a miR-590-3p Sponge to Facilitate Low Concentration Oxidized Low-Density Lipoprotein–Induced Angiogenesis
      You have access
      Long Noncoding RNA LINC00657 Acting as a miR-590-3p Sponge to Facilitate Low Concentration Oxidized Low-Density Lipoprotein–Induced Angiogenesis
      Mei-Hua Bao, Guang-Yi Li, Xiao-Shan Huang, Liang Tang, Li-Ping Dong and Jian-Ming Li
      Molecular Pharmacology April 2018, 93 (4) 368-375; DOI: https://doi.org/10.1124/mol.117.110650

I

  1. Insel, Paul A.

    1. You have access
      G Protein-Coupled Receptors as Targets for Approved Drugs: How Many Targets and How Many Drugs?
      Krishna Sriram and Paul A. Insel
      Molecular Pharmacology April 2018, 93 (4) 251-258; DOI: https://doi.org/10.1124/mol.117.111062

J

  1. Jacobs, Blaine A.

    1. You have access
      Allosterism within δ Opioid–κ Opioid Receptor Heteromers in Peripheral Sensory Neurons: Regulation of κ Opioid Agonist Efficacy
      Blaine A. Jacobs, Miryam M. Pando, Elaine Jennings, Teresa A. Chavera, William P. Clarke and Kelly A. Berg
      Molecular Pharmacology April 2018, 93 (4) 376-386; DOI: https://doi.org/10.1124/mol.117.109975
  2. Jennings, Elaine

    1. You have access
      Allosterism within δ Opioid–κ Opioid Receptor Heteromers in Peripheral Sensory Neurons: Regulation of κ Opioid Agonist Efficacy
      Blaine A. Jacobs, Miryam M. Pando, Elaine Jennings, Teresa A. Chavera, William P. Clarke and Kelly A. Berg
      Molecular Pharmacology April 2018, 93 (4) 376-386; DOI: https://doi.org/10.1124/mol.117.109975
  3. Johnstone, Timothy B.

    1. You have access
      cAMP Signaling Compartmentation: Adenylyl Cyclases as Anchors of Dynamic Signaling Complexes
      Timothy B. Johnstone, Shailesh R. Agarwal, Robert D. Harvey and Rennolds S. Ostrom
      Molecular Pharmacology April 2018, 93 (4) 270-276; DOI: https://doi.org/10.1124/mol.117.110825

K

  1. Kaiser, Anette

    1. You have access
      G Protein Preassembly Rescues Efficacy of W6.48 Toggle Mutations in Neuropeptide Y2 Receptor
      Anette Kaiser, Caroline Hempel, Lizzy Wanka, Mario Schubert, Heidi E. Hamm and Annette G. Beck-Sickinger
      Molecular Pharmacology April 2018, 93 (4) 387-401; DOI: https://doi.org/10.1124/mol.117.110544
  2. Kenakin, Terry

    1. You have access
      Is the Quest for Signaling Bias Worth the Effort?
      Terry Kenakin
      Molecular Pharmacology April 2018, 93 (4) 266-269; DOI: https://doi.org/10.1124/mol.117.111187
  3. Kensler, Thomas W.

    1. Open Access
      Pharmacogenomics of Chemically Distinct Classes of Keap1-Nrf2 Activators Identify Common and Unique Gene, Protein, and Pathway Responses In Vivo
      Ryan S. Wible, Quynh T. Tran, Samreen Fathima, Carrie H. Sutter, Thomas W. Kensler and Thomas R. Sutter
      Molecular Pharmacology April 2018, 93 (4) 297-308; DOI: https://doi.org/10.1124/mol.117.110262
  4. Kiechle, Tobias

    1. You have access
      Identifying Functional Hotspot Residues for Biased Ligand Design in G-Protein-Coupled Receptors
      Anita K. Nivedha, Christofer S. Tautermann, Supriyo Bhattacharya, Sangbae Lee, Paola Casarosa, Ines Kollak, Tobias Kiechle and Nagarajan Vaidehi
      Molecular Pharmacology April 2018, 93 (4) 288-296; DOI: https://doi.org/10.1124/mol.117.110395
  5. Koepsell, Hermann

    1. You have access
      Assay Conditions Influence Affinities of Rat Organic Cation Transporter 1: Analysis of Mutagenesis in the Modeled Outward-Facing Cleft by Measuring Effects of Substrates and Inhibitors on Initial Uptake
      Valentin Gorboulev, Saba Rehman, Christoph M. Albert, Ursula Roth, Marleen J. Meyer, Mladen V. Tzvetkov, Thomas D. Mueller and Hermann Koepsell
      Molecular Pharmacology April 2018, 93 (4) 402-415; DOI: https://doi.org/10.1124/mol.117.110767
  6. Kollak, Ines

    1. You have access
      Identifying Functional Hotspot Residues for Biased Ligand Design in G-Protein-Coupled Receptors
      Anita K. Nivedha, Christofer S. Tautermann, Supriyo Bhattacharya, Sangbae Lee, Paola Casarosa, Ines Kollak, Tobias Kiechle and Nagarajan Vaidehi
      Molecular Pharmacology April 2018, 93 (4) 288-296; DOI: https://doi.org/10.1124/mol.117.110395
  7. Kollau, Alexander

    1. Open Access
      Sustained Formation of Nitroglycerin-Derived Nitric Oxide by Aldehyde Dehydrogenase-2 in Vascular Smooth Muscle without Added Reductants: Implications for the Development of Nitrate Tolerance
      Marissa Opelt, Gerald Wölkart, Emrah Eroglu, Markus Waldeck-Weiermair, Roland Malli, Wolfgang F. Graier, Alexander Kollau, John T. Fassett, Astrid Schrammel, Bernd Mayer and Antonius C. F. Gorren
      Molecular Pharmacology April 2018, 93 (4) 335-343; DOI: https://doi.org/10.1124/mol.117.110783

L

  1. Larhammar, Dan

    1. Open Access
      Elucidation of the Binding Mode of the Carboxyterminal Region of Peptide YY to the Human Y2 Receptor
      Bo Xu, Silvana Vasile, Søren Østergaard, Johan F. Paulsson, Jasna Pruner, Johan Åqvist, Birgitte S. Wulff, Hugo Gutiérrez-de-Terán and Dan Larhammar
      Molecular Pharmacology April 2018, 93 (4) 323-334; DOI: https://doi.org/10.1124/mol.117.110627
  2. Lee, Sangbae

    1. You have access
      Identifying Functional Hotspot Residues for Biased Ligand Design in G-Protein-Coupled Receptors
      Anita K. Nivedha, Christofer S. Tautermann, Supriyo Bhattacharya, Sangbae Lee, Paola Casarosa, Ines Kollak, Tobias Kiechle and Nagarajan Vaidehi
      Molecular Pharmacology April 2018, 93 (4) 288-296; DOI: https://doi.org/10.1124/mol.117.110395
  3. Li, Guang-Yi

    1. Long Noncoding RNA LINC00657 Acting as a miR-590-3p Sponge to Facilitate Low Concentration Oxidized Low-Density Lipoprotein–Induced Angiogenesis
      You have access
      Long Noncoding RNA LINC00657 Acting as a miR-590-3p Sponge to Facilitate Low Concentration Oxidized Low-Density Lipoprotein–Induced Angiogenesis
      Mei-Hua Bao, Guang-Yi Li, Xiao-Shan Huang, Liang Tang, Li-Ping Dong and Jian-Ming Li
      Molecular Pharmacology April 2018, 93 (4) 368-375; DOI: https://doi.org/10.1124/mol.117.110650
  4. Li, Jian-Ming

    1. Long Noncoding RNA LINC00657 Acting as a miR-590-3p Sponge to Facilitate Low Concentration Oxidized Low-Density Lipoprotein–Induced Angiogenesis
      You have access
      Long Noncoding RNA LINC00657 Acting as a miR-590-3p Sponge to Facilitate Low Concentration Oxidized Low-Density Lipoprotein–Induced Angiogenesis
      Mei-Hua Bao, Guang-Yi Li, Xiao-Shan Huang, Liang Tang, Li-Ping Dong and Jian-Ming Li
      Molecular Pharmacology April 2018, 93 (4) 368-375; DOI: https://doi.org/10.1124/mol.117.110650

M

  1. Malli, Roland

    1. Open Access
      Sustained Formation of Nitroglycerin-Derived Nitric Oxide by Aldehyde Dehydrogenase-2 in Vascular Smooth Muscle without Added Reductants: Implications for the Development of Nitrate Tolerance
      Marissa Opelt, Gerald Wölkart, Emrah Eroglu, Markus Waldeck-Weiermair, Roland Malli, Wolfgang F. Graier, Alexander Kollau, John T. Fassett, Astrid Schrammel, Bernd Mayer and Antonius C. F. Gorren
      Molecular Pharmacology April 2018, 93 (4) 335-343; DOI: https://doi.org/10.1124/mol.117.110783
  2. Mayer, Bernd

    1. Open Access
      Sustained Formation of Nitroglycerin-Derived Nitric Oxide by Aldehyde Dehydrogenase-2 in Vascular Smooth Muscle without Added Reductants: Implications for the Development of Nitrate Tolerance
      Marissa Opelt, Gerald Wölkart, Emrah Eroglu, Markus Waldeck-Weiermair, Roland Malli, Wolfgang F. Graier, Alexander Kollau, John T. Fassett, Astrid Schrammel, Bernd Mayer and Antonius C. F. Gorren
      Molecular Pharmacology April 2018, 93 (4) 335-343; DOI: https://doi.org/10.1124/mol.117.110783
  3. Meyer, Marleen J.

    1. You have access
      Assay Conditions Influence Affinities of Rat Organic Cation Transporter 1: Analysis of Mutagenesis in the Modeled Outward-Facing Cleft by Measuring Effects of Substrates and Inhibitors on Initial Uptake
      Valentin Gorboulev, Saba Rehman, Christoph M. Albert, Ursula Roth, Marleen J. Meyer, Mladen V. Tzvetkov, Thomas D. Mueller and Hermann Koepsell
      Molecular Pharmacology April 2018, 93 (4) 402-415; DOI: https://doi.org/10.1124/mol.117.110767
  4. Michel, Martin C.

    1. You have access
      Biased Agonism in Drug Discovery—Is It Too Soon to Choose a Path?
      Martin C. Michel and Steven J. Charlton
      Molecular Pharmacology April 2018, 93 (4) 259-265; DOI: https://doi.org/10.1124/mol.117.110890
  5. Milanos, Lampros

    1. You have access
      Molecular Mechanisms of Biased and Probe-Dependent Signaling at CXC-Motif Chemokine Receptor CXCR3 Induced by Negative Allosteric Modulators
      Regine Brox, Lampros Milanos, Noureldin Saleh, Paul Baumeister, Armin Buschauer, Dagmar Hofmann, Markus R. Heinrich, Timothy Clark and Nuska Tschammer
      Molecular Pharmacology April 2018, 93 (4) 309-322; DOI: https://doi.org/10.1124/mol.117.110296
  6. Moolman, Wessel J. A.

    1. Open Access
      Investigation into the Mechanism of Homo- and Heterodimerization of Angiotensin-Converting Enzyme
      J. Albert Abrie, Wessel J. A. Moolman, Gyles E. Cozier, Sylva L. Schwager, K. Ravi Acharya and Edward D. Sturrock
      Molecular Pharmacology April 2018, 93 (4) 344-354; DOI: https://doi.org/10.1124/mol.117.110866
  7. Mueller, Thomas D.

    1. You have access
      Assay Conditions Influence Affinities of Rat Organic Cation Transporter 1: Analysis of Mutagenesis in the Modeled Outward-Facing Cleft by Measuring Effects of Substrates and Inhibitors on Initial Uptake
      Valentin Gorboulev, Saba Rehman, Christoph M. Albert, Ursula Roth, Marleen J. Meyer, Mladen V. Tzvetkov, Thomas D. Mueller and Hermann Koepsell
      Molecular Pharmacology April 2018, 93 (4) 402-415; DOI: https://doi.org/10.1124/mol.117.110767

N

  1. Nivedha, Anita K.

    1. You have access
      Identifying Functional Hotspot Residues for Biased Ligand Design in G-Protein-Coupled Receptors
      Anita K. Nivedha, Christofer S. Tautermann, Supriyo Bhattacharya, Sangbae Lee, Paola Casarosa, Ines Kollak, Tobias Kiechle and Nagarajan Vaidehi
      Molecular Pharmacology April 2018, 93 (4) 288-296; DOI: https://doi.org/10.1124/mol.117.110395

O

  1. Opelt, Marissa

    1. Open Access
      Sustained Formation of Nitroglycerin-Derived Nitric Oxide by Aldehyde Dehydrogenase-2 in Vascular Smooth Muscle without Added Reductants: Implications for the Development of Nitrate Tolerance
      Marissa Opelt, Gerald Wölkart, Emrah Eroglu, Markus Waldeck-Weiermair, Roland Malli, Wolfgang F. Graier, Alexander Kollau, John T. Fassett, Astrid Schrammel, Bernd Mayer and Antonius C. F. Gorren
      Molecular Pharmacology April 2018, 93 (4) 335-343; DOI: https://doi.org/10.1124/mol.117.110783
  2. Østergaard, Søren

    1. Open Access
      Elucidation of the Binding Mode of the Carboxyterminal Region of Peptide YY to the Human Y2 Receptor
      Bo Xu, Silvana Vasile, Søren Østergaard, Johan F. Paulsson, Jasna Pruner, Johan Åqvist, Birgitte S. Wulff, Hugo Gutiérrez-de-Terán and Dan Larhammar
      Molecular Pharmacology April 2018, 93 (4) 323-334; DOI: https://doi.org/10.1124/mol.117.110627
  3. Ostrom, Rennolds S.

    1. You have access
      cAMP Signaling Compartmentation: Adenylyl Cyclases as Anchors of Dynamic Signaling Complexes
      Timothy B. Johnstone, Shailesh R. Agarwal, Robert D. Harvey and Rennolds S. Ostrom
      Molecular Pharmacology April 2018, 93 (4) 270-276; DOI: https://doi.org/10.1124/mol.117.110825

P

  1. Pando, Miryam M.

    1. You have access
      Allosterism within δ Opioid–κ Opioid Receptor Heteromers in Peripheral Sensory Neurons: Regulation of κ Opioid Agonist Efficacy
      Blaine A. Jacobs, Miryam M. Pando, Elaine Jennings, Teresa A. Chavera, William P. Clarke and Kelly A. Berg
      Molecular Pharmacology April 2018, 93 (4) 376-386; DOI: https://doi.org/10.1124/mol.117.109975
  2. Patel, Hemal H.

    1. You have access
      Caveolins as Regulators of Stress Adaptation
      Jan M. Schilling, Brian P. Head and Hemal H. Patel
      Molecular Pharmacology April 2018, 93 (4) 277-285; DOI: https://doi.org/10.1124/mol.117.111237
  3. Paulsson, Johan F.

    1. Open Access
      Elucidation of the Binding Mode of the Carboxyterminal Region of Peptide YY to the Human Y2 Receptor
      Bo Xu, Silvana Vasile, Søren Østergaard, Johan F. Paulsson, Jasna Pruner, Johan Åqvist, Birgitte S. Wulff, Hugo Gutiérrez-de-Terán and Dan Larhammar
      Molecular Pharmacology April 2018, 93 (4) 323-334; DOI: https://doi.org/10.1124/mol.117.110627
  4. Pioszak, Augen A.

    1. You have access
      Probing the Mechanism of Receptor Activity–Modifying Protein Modulation of GPCR Ligand Selectivity through Rational Design of Potent Adrenomedullin and Calcitonin Gene-Related Peptide Antagonists
      Jason M. Booe, Margaret L. Warner, Amanda M. Roehrkasse, Debbie L. Hay and Augen A. Pioszak
      Molecular Pharmacology April 2018, 93 (4) 355-367; DOI: https://doi.org/10.1124/mol.117.110916
  5. Pruner, Jasna

    1. Open Access
      Elucidation of the Binding Mode of the Carboxyterminal Region of Peptide YY to the Human Y2 Receptor
      Bo Xu, Silvana Vasile, Søren Østergaard, Johan F. Paulsson, Jasna Pruner, Johan Åqvist, Birgitte S. Wulff, Hugo Gutiérrez-de-Terán and Dan Larhammar
      Molecular Pharmacology April 2018, 93 (4) 323-334; DOI: https://doi.org/10.1124/mol.117.110627

R

  1. Rehman, Saba

    1. You have access
      Assay Conditions Influence Affinities of Rat Organic Cation Transporter 1: Analysis of Mutagenesis in the Modeled Outward-Facing Cleft by Measuring Effects of Substrates and Inhibitors on Initial Uptake
      Valentin Gorboulev, Saba Rehman, Christoph M. Albert, Ursula Roth, Marleen J. Meyer, Mladen V. Tzvetkov, Thomas D. Mueller and Hermann Koepsell
      Molecular Pharmacology April 2018, 93 (4) 402-415; DOI: https://doi.org/10.1124/mol.117.110767
  2. Roehrkasse, Amanda M.

    1. You have access
      Probing the Mechanism of Receptor Activity–Modifying Protein Modulation of GPCR Ligand Selectivity through Rational Design of Potent Adrenomedullin and Calcitonin Gene-Related Peptide Antagonists
      Jason M. Booe, Margaret L. Warner, Amanda M. Roehrkasse, Debbie L. Hay and Augen A. Pioszak
      Molecular Pharmacology April 2018, 93 (4) 355-367; DOI: https://doi.org/10.1124/mol.117.110916
  3. Roth, Ursula

    1. You have access
      Assay Conditions Influence Affinities of Rat Organic Cation Transporter 1: Analysis of Mutagenesis in the Modeled Outward-Facing Cleft by Measuring Effects of Substrates and Inhibitors on Initial Uptake
      Valentin Gorboulev, Saba Rehman, Christoph M. Albert, Ursula Roth, Marleen J. Meyer, Mladen V. Tzvetkov, Thomas D. Mueller and Hermann Koepsell
      Molecular Pharmacology April 2018, 93 (4) 402-415; DOI: https://doi.org/10.1124/mol.117.110767

S

  1. Saleh, Noureldin

    1. You have access
      Molecular Mechanisms of Biased and Probe-Dependent Signaling at CXC-Motif Chemokine Receptor CXCR3 Induced by Negative Allosteric Modulators
      Regine Brox, Lampros Milanos, Noureldin Saleh, Paul Baumeister, Armin Buschauer, Dagmar Hofmann, Markus R. Heinrich, Timothy Clark and Nuska Tschammer
      Molecular Pharmacology April 2018, 93 (4) 309-322; DOI: https://doi.org/10.1124/mol.117.110296
  2. Schilling, Jan M.

    1. You have access
      Caveolins as Regulators of Stress Adaptation
      Jan M. Schilling, Brian P. Head and Hemal H. Patel
      Molecular Pharmacology April 2018, 93 (4) 277-285; DOI: https://doi.org/10.1124/mol.117.111237
  3. Schrammel, Astrid

    1. Open Access
      Sustained Formation of Nitroglycerin-Derived Nitric Oxide by Aldehyde Dehydrogenase-2 in Vascular Smooth Muscle without Added Reductants: Implications for the Development of Nitrate Tolerance
      Marissa Opelt, Gerald Wölkart, Emrah Eroglu, Markus Waldeck-Weiermair, Roland Malli, Wolfgang F. Graier, Alexander Kollau, John T. Fassett, Astrid Schrammel, Bernd Mayer and Antonius C. F. Gorren
      Molecular Pharmacology April 2018, 93 (4) 335-343; DOI: https://doi.org/10.1124/mol.117.110783
  4. Schubert, Mario

    1. You have access
      G Protein Preassembly Rescues Efficacy of W6.48 Toggle Mutations in Neuropeptide Y2 Receptor
      Anette Kaiser, Caroline Hempel, Lizzy Wanka, Mario Schubert, Heidi E. Hamm and Annette G. Beck-Sickinger
      Molecular Pharmacology April 2018, 93 (4) 387-401; DOI: https://doi.org/10.1124/mol.117.110544
  5. Schwager, Sylva L.

    1. Open Access
      Investigation into the Mechanism of Homo- and Heterodimerization of Angiotensin-Converting Enzyme
      J. Albert Abrie, Wessel J. A. Moolman, Gyles E. Cozier, Sylva L. Schwager, K. Ravi Acharya and Edward D. Sturrock
      Molecular Pharmacology April 2018, 93 (4) 344-354; DOI: https://doi.org/10.1124/mol.117.110866
  6. Sriram, Krishna

    1. You have access
      G Protein-Coupled Receptors as Targets for Approved Drugs: How Many Targets and How Many Drugs?
      Krishna Sriram and Paul A. Insel
      Molecular Pharmacology April 2018, 93 (4) 251-258; DOI: https://doi.org/10.1124/mol.117.111062
  7. Sturrock, Edward D.

    1. Open Access
      Investigation into the Mechanism of Homo- and Heterodimerization of Angiotensin-Converting Enzyme
      J. Albert Abrie, Wessel J. A. Moolman, Gyles E. Cozier, Sylva L. Schwager, K. Ravi Acharya and Edward D. Sturrock
      Molecular Pharmacology April 2018, 93 (4) 344-354; DOI: https://doi.org/10.1124/mol.117.110866
  8. Sutter, Carrie H.

    1. Open Access
      Pharmacogenomics of Chemically Distinct Classes of Keap1-Nrf2 Activators Identify Common and Unique Gene, Protein, and Pathway Responses In Vivo
      Ryan S. Wible, Quynh T. Tran, Samreen Fathima, Carrie H. Sutter, Thomas W. Kensler and Thomas R. Sutter
      Molecular Pharmacology April 2018, 93 (4) 297-308; DOI: https://doi.org/10.1124/mol.117.110262
  9. Sutter, Thomas R.

    1. Open Access
      Pharmacogenomics of Chemically Distinct Classes of Keap1-Nrf2 Activators Identify Common and Unique Gene, Protein, and Pathway Responses In Vivo
      Ryan S. Wible, Quynh T. Tran, Samreen Fathima, Carrie H. Sutter, Thomas W. Kensler and Thomas R. Sutter
      Molecular Pharmacology April 2018, 93 (4) 297-308; DOI: https://doi.org/10.1124/mol.117.110262

T

  1. Tang, Liang

    1. Long Noncoding RNA LINC00657 Acting as a miR-590-3p Sponge to Facilitate Low Concentration Oxidized Low-Density Lipoprotein–Induced Angiogenesis
      You have access
      Long Noncoding RNA LINC00657 Acting as a miR-590-3p Sponge to Facilitate Low Concentration Oxidized Low-Density Lipoprotein–Induced Angiogenesis
      Mei-Hua Bao, Guang-Yi Li, Xiao-Shan Huang, Liang Tang, Li-Ping Dong and Jian-Ming Li
      Molecular Pharmacology April 2018, 93 (4) 368-375; DOI: https://doi.org/10.1124/mol.117.110650
  2. Tautermann, Christofer S.

    1. You have access
      Identifying Functional Hotspot Residues for Biased Ligand Design in G-Protein-Coupled Receptors
      Anita K. Nivedha, Christofer S. Tautermann, Supriyo Bhattacharya, Sangbae Lee, Paola Casarosa, Ines Kollak, Tobias Kiechle and Nagarajan Vaidehi
      Molecular Pharmacology April 2018, 93 (4) 288-296; DOI: https://doi.org/10.1124/mol.117.110395
  3. Tran, Quynh T.

    1. Open Access
      Pharmacogenomics of Chemically Distinct Classes of Keap1-Nrf2 Activators Identify Common and Unique Gene, Protein, and Pathway Responses In Vivo
      Ryan S. Wible, Quynh T. Tran, Samreen Fathima, Carrie H. Sutter, Thomas W. Kensler and Thomas R. Sutter
      Molecular Pharmacology April 2018, 93 (4) 297-308; DOI: https://doi.org/10.1124/mol.117.110262
  4. Tschammer, Nuska

    1. You have access
      Molecular Mechanisms of Biased and Probe-Dependent Signaling at CXC-Motif Chemokine Receptor CXCR3 Induced by Negative Allosteric Modulators
      Regine Brox, Lampros Milanos, Noureldin Saleh, Paul Baumeister, Armin Buschauer, Dagmar Hofmann, Markus R. Heinrich, Timothy Clark and Nuska Tschammer
      Molecular Pharmacology April 2018, 93 (4) 309-322; DOI: https://doi.org/10.1124/mol.117.110296
  5. Tzvetkov, Mladen V.

    1. You have access
      Assay Conditions Influence Affinities of Rat Organic Cation Transporter 1: Analysis of Mutagenesis in the Modeled Outward-Facing Cleft by Measuring Effects of Substrates and Inhibitors on Initial Uptake
      Valentin Gorboulev, Saba Rehman, Christoph M. Albert, Ursula Roth, Marleen J. Meyer, Mladen V. Tzvetkov, Thomas D. Mueller and Hermann Koepsell
      Molecular Pharmacology April 2018, 93 (4) 402-415; DOI: https://doi.org/10.1124/mol.117.110767

V

  1. Vaidehi, Nagarajan

    1. You have access
      Identifying Functional Hotspot Residues for Biased Ligand Design in G-Protein-Coupled Receptors
      Anita K. Nivedha, Christofer S. Tautermann, Supriyo Bhattacharya, Sangbae Lee, Paola Casarosa, Ines Kollak, Tobias Kiechle and Nagarajan Vaidehi
      Molecular Pharmacology April 2018, 93 (4) 288-296; DOI: https://doi.org/10.1124/mol.117.110395
  2. Vasile, Silvana

    1. Open Access
      Elucidation of the Binding Mode of the Carboxyterminal Region of Peptide YY to the Human Y2 Receptor
      Bo Xu, Silvana Vasile, Søren Østergaard, Johan F. Paulsson, Jasna Pruner, Johan Åqvist, Birgitte S. Wulff, Hugo Gutiérrez-de-Terán and Dan Larhammar
      Molecular Pharmacology April 2018, 93 (4) 323-334; DOI: https://doi.org/10.1124/mol.117.110627
  3. Vore, Mary

    1. You have access
      Publishing in an ASPET Journal – What’s in It for You?
      Mary Vore
      Molecular Pharmacology April 2018, 93 (4) 286-287; DOI: https://doi.org/10.1124/mol.117.112193

W

  1. Waldeck-Weiermair, Markus

    1. Open Access
      Sustained Formation of Nitroglycerin-Derived Nitric Oxide by Aldehyde Dehydrogenase-2 in Vascular Smooth Muscle without Added Reductants: Implications for the Development of Nitrate Tolerance
      Marissa Opelt, Gerald Wölkart, Emrah Eroglu, Markus Waldeck-Weiermair, Roland Malli, Wolfgang F. Graier, Alexander Kollau, John T. Fassett, Astrid Schrammel, Bernd Mayer and Antonius C. F. Gorren
      Molecular Pharmacology April 2018, 93 (4) 335-343; DOI: https://doi.org/10.1124/mol.117.110783
  2. Wanka, Lizzy

    1. You have access
      G Protein Preassembly Rescues Efficacy of W6.48 Toggle Mutations in Neuropeptide Y2 Receptor
      Anette Kaiser, Caroline Hempel, Lizzy Wanka, Mario Schubert, Heidi E. Hamm and Annette G. Beck-Sickinger
      Molecular Pharmacology April 2018, 93 (4) 387-401; DOI: https://doi.org/10.1124/mol.117.110544
  3. Warner, Margaret L.

    1. You have access
      Probing the Mechanism of Receptor Activity–Modifying Protein Modulation of GPCR Ligand Selectivity through Rational Design of Potent Adrenomedullin and Calcitonin Gene-Related Peptide Antagonists
      Jason M. Booe, Margaret L. Warner, Amanda M. Roehrkasse, Debbie L. Hay and Augen A. Pioszak
      Molecular Pharmacology April 2018, 93 (4) 355-367; DOI: https://doi.org/10.1124/mol.117.110916
  4. Wible, Ryan S.

    1. Open Access
      Pharmacogenomics of Chemically Distinct Classes of Keap1-Nrf2 Activators Identify Common and Unique Gene, Protein, and Pathway Responses In Vivo
      Ryan S. Wible, Quynh T. Tran, Samreen Fathima, Carrie H. Sutter, Thomas W. Kensler and Thomas R. Sutter
      Molecular Pharmacology April 2018, 93 (4) 297-308; DOI: https://doi.org/10.1124/mol.117.110262
  5. Wölkart, Gerald

    1. Open Access
      Sustained Formation of Nitroglycerin-Derived Nitric Oxide by Aldehyde Dehydrogenase-2 in Vascular Smooth Muscle without Added Reductants: Implications for the Development of Nitrate Tolerance
      Marissa Opelt, Gerald Wölkart, Emrah Eroglu, Markus Waldeck-Weiermair, Roland Malli, Wolfgang F. Graier, Alexander Kollau, John T. Fassett, Astrid Schrammel, Bernd Mayer and Antonius C. F. Gorren
      Molecular Pharmacology April 2018, 93 (4) 335-343; DOI: https://doi.org/10.1124/mol.117.110783
  6. Wulff, Birgitte S.

    1. Open Access
      Elucidation of the Binding Mode of the Carboxyterminal Region of Peptide YY to the Human Y2 Receptor
      Bo Xu, Silvana Vasile, Søren Østergaard, Johan F. Paulsson, Jasna Pruner, Johan Åqvist, Birgitte S. Wulff, Hugo Gutiérrez-de-Terán and Dan Larhammar
      Molecular Pharmacology April 2018, 93 (4) 323-334; DOI: https://doi.org/10.1124/mol.117.110627

X

  1. Xu, Bo

    1. Open Access
      Elucidation of the Binding Mode of the Carboxyterminal Region of Peptide YY to the Human Y2 Receptor
      Bo Xu, Silvana Vasile, Søren Østergaard, Johan F. Paulsson, Jasna Pruner, Johan Åqvist, Birgitte S. Wulff, Hugo Gutiérrez-de-Terán and Dan Larhammar
      Molecular Pharmacology April 2018, 93 (4) 323-334; DOI: https://doi.org/10.1124/mol.117.110627
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Molecular Pharmacology: 93 (4)
Molecular Pharmacology
Vol. 93, Issue 4
1 Apr 2018
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  • SB-431542 Is a Potent and Specific Inhibitor of Transforming Growth Factor-β Superfamily Type I Activin Receptor-Like Kinase (ALK) Receptors ALK4, ALK5, and ALK7
  • The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints
  • Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases
  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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