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Molecular Pharmacology

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Rapid CommunicationMinireview—Axelrod Symposium 2017

cAMP Signaling Compartmentation: Adenylyl Cyclases as Anchors of Dynamic Signaling Complexes

Timothy B. Johnstone, Shailesh R. Agarwal, Robert D. Harvey and Rennolds S. Ostrom
Molecular Pharmacology April 2018, 93 (4) 270-276; DOI: https://doi.org/10.1124/mol.117.110825
Timothy B. Johnstone
Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, Irvine, California (T.B.J., R.S.O.); and Department of Pharmacology, University of Nevada, Reno School of Medicine, Reno Nevada (S.R.A., R.D.H.)
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Shailesh R. Agarwal
Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, Irvine, California (T.B.J., R.S.O.); and Department of Pharmacology, University of Nevada, Reno School of Medicine, Reno Nevada (S.R.A., R.D.H.)
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Robert D. Harvey
Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, Irvine, California (T.B.J., R.S.O.); and Department of Pharmacology, University of Nevada, Reno School of Medicine, Reno Nevada (S.R.A., R.D.H.)
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Rennolds S. Ostrom
Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, Irvine, California (T.B.J., R.S.O.); and Department of Pharmacology, University of Nevada, Reno School of Medicine, Reno Nevada (S.R.A., R.D.H.)
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Article Information

vol. 93 no. 4 270-276
DOI 
https://doi.org/10.1124/mol.117.110825
PubMed 
29217670

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received October 9, 2017
  • Accepted December 4, 2017
  • Published online February 20, 2018.

Article Versions

  • Earlier version (December 7, 2017 - 05:54).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2018 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Timothy B. Johnstone,
  2. Shailesh R. Agarwal,
  3. Robert D. Harvey, and
  4. Rennolds S. Ostrom
  1. Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, Irvine, California (T.B.J., R.S.O.); and Department of Pharmacology, University of Nevada, Reno School of Medicine, Reno Nevada (S.R.A., R.D.H.)
  1. Address correspondence to:
    Dr. Rennolds S. Ostrom, Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, 9501 Jeronimo Rd., Irvine, CA 92618. E-mail: rostrom{at}chapman.edu
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Molecular Pharmacology: 93 (4)
Molecular Pharmacology
Vol. 93, Issue 4
1 Apr 2018
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Rapid CommunicationMinireview—Axelrod Symposium 2017

Adenylyl Cyclases Anchor cAMP Compartments

Timothy B. Johnstone, Shailesh R. Agarwal, Robert D. Harvey and Rennolds S. Ostrom
Molecular Pharmacology April 1, 2018, 93 (4) 270-276; DOI: https://doi.org/10.1124/mol.117.110825

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Rapid CommunicationMinireview—Axelrod Symposium 2017

Adenylyl Cyclases Anchor cAMP Compartments

Timothy B. Johnstone, Shailesh R. Agarwal, Robert D. Harvey and Rennolds S. Ostrom
Molecular Pharmacology April 1, 2018, 93 (4) 270-276; DOI: https://doi.org/10.1124/mol.117.110825
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  • Article
    • Abstract
    • Introduction
    • Localized Signal Generation
    • Restriction of Signal Diffusion
    • Localization of Downstream Effectors
    • From a Signal to a Response
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  • Biased Agonism in Drug Discovery
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Show more Minireview—Axelrod Symposium 2017

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