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Molecular Pharmacology

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Table of Contents

May 01, 2018; Volume 93,Issue 5

Accelerated Communication

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    High Constitutive Activity Accounts for the Combination of Enhanced Direct Activation and Reduced Potentiation in Mutated GABAA Receptors
    Allison L. Germann, Daniel J. Shin, Christina R. Kuhrau, Alexander D. Johnson, Alex S. Evers and Gustav Akk
    Molecular Pharmacology May 2018, 93 (5) 468-476; DOI: https://doi.org/10.1124/mol.117.111435

Articles

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    Ethanol Reversal of Oxycodone Tolerance in Dorsal Root Ganglia Neurons
    Joanna C. Jacob, Kensuke Sakakibara, Ryan A. Mischel, Graeme Henderson, William L. Dewey and Hamid I. Akbarali
    Molecular Pharmacology May 2018, 93 (5) 417-426; DOI: https://doi.org/10.1124/mol.117.110775
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    Hemodynamic Effects of Glutathione-Liganded Binuclear Dinitrosyl Iron Complex: Evidence for Nitroxyl Generation and Modulation by Plasma Albumin
    Taiming Liu, Meijuan Zhang, Michael H. Terry, Hobe Schroeder, Sean M. Wilson, Gordon G. Power, Qian Li, Trent E. Tipple, Dan Borchardt and Arlin B. Blood
    Molecular Pharmacology May 2018, 93 (5) 427-437; DOI: https://doi.org/10.1124/mol.117.110957
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    Retinal-chitosan Conjugates Effectively Deliver Active Chromophores to Retinal Photoreceptor Cells in Blind Mice and Dogs
    Songqi Gao, Shirin Kahremany, Jianye Zhang, Beata Jastrzebska, Janice Querubin, Simon M. Petersen-Jones and Krzysztof Palczewski
    Molecular Pharmacology May 2018, 93 (5) 438-452; DOI: https://doi.org/10.1124/mol.117.111294
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    Properties of Triheteromeric N-Methyl-d-Aspartate Receptors Containing Two Distinct GluN1 Isoforms
    Feng Yi, Linda G. Zachariassen, Katherine N. Dorsett and Kasper B. Hansen
    Molecular Pharmacology May 2018, 93 (5) 453-467; DOI: https://doi.org/10.1124/mol.117.111427
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    Gedunin- and Khivorin-Derivatives Are Small-Molecule Partial Agonists for Adhesion G Protein-Coupled Receptors GPR56/ADGRG1 and GPR114/ADGRG5
    Hannah M. Stoveken, Scott D. Larsen, Alan V. Smrcka and Gregory G. Tall
    Molecular Pharmacology May 2018, 93 (5) 477-488; DOI: https://doi.org/10.1124/mol.117.111476
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    CYP26C1 Is a Hydroxylase of Multiple Active Retinoids and Interacts with Cellular Retinoic Acid Binding Proteins
    Guo Zhong, David Ortiz, Alex Zelter, Abhinav Nath and Nina Isoherranen
    Molecular Pharmacology May 2018, 93 (5) 489-503; DOI: https://doi.org/10.1124/mol.117.111039
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    “Selective” Class C G Protein-Coupled Receptor Modulators Are Neutral or Biased mGlu5 Allosteric Ligands
    Shane D. Hellyer, Sabine Albold, Taide Wang, Amy N. Y. Chen, Lauren T. May, Katie Leach and Karen J. Gregory
    Molecular Pharmacology May 2018, 93 (5) 504-514; DOI: https://doi.org/10.1124/mol.117.111518
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    The Novel C-terminal Truncated 90-kDa Isoform of Topoisomerase IIα (TOP2α/90) Is a Determinant of Etoposide Resistance in K562 Leukemia Cells via Heterodimerization with the TOP2α/170 Isoform
    Ragu Kanagasabai, Soumendrakrishna Karmahapatra, Corey A. Kientz, Yang Yu, Victor A. Hernandez, Evan E. Kania, Jack C. Yalowich and Terry S. Elton
    Molecular Pharmacology May 2018, 93 (5) 515-525; DOI: https://doi.org/10.1124/mol.117.111567
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    Differential Pharmacology and Binding of mGlu2 Receptor Allosteric Modulators
    Daniel E. O’Brien, Douglas M. Shaw, Hyekyung P. Cho, Alan J. Cross, Steven S. Wesolowski, Andrew S. Felts, Jonas Bergare, Charles S. Elmore, Craig W. Lindsley, Colleen M. Niswender and P. Jeffrey Conn
    Molecular Pharmacology May 2018, 93 (5) 526-540; DOI: https://doi.org/10.1124/mol.117.110114
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    Cooperative Regulation of Intestinal UDP-Glucuronosyltransferases 1A8, -1A9, and 1A10 by CDX2 and HNF4α Is Mediated by a Novel Composite Regulatory Element
    Nurul Mubarokah, Julie-Ann Hulin, Peter I. Mackenzie, Ross A. McKinnon, Alex Z. Haines, Dong Gui Hu and Robyn Meech
    Molecular Pharmacology May 2018, 93 (5) 541-552; DOI: https://doi.org/10.1124/mol.117.110619
  • Open Access
    Mapping the Allosteric Action of Antagonists A740003 and A438079 Reveals a Role for the Left Flipper in Ligand Sensitivity at P2X7 Receptors
    Rebecca C. Allsopp, Sudad Dayl, Anfal Bin Dayel, Ralf Schmid and Richard J. Evans
    Molecular Pharmacology May 2018, 93 (5) 553-562; DOI: https://doi.org/10.1124/mol.117.111021

Erratum

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    Correction to “Investigation into the Mechanism of Homo- and Heterodimerization of Angiotensin-Converting Enzyme”
    Molecular Pharmacology May 2018, 93 (5) 416; DOI: https://doi.org/10.1124/mol.117.110866err
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In this issue

Molecular Pharmacology: 93 (5)
Molecular Pharmacology
Vol. 93, Issue 5
1 May 2018
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  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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