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Molecular Pharmacology

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Index by author

June 01, 2018; Volume 93,Issue 6
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Arnoult, Eric

    1. GPR40-Mediated G<em>α</em>12 Activation by Allosteric Full Agonists Highly Efficacious at Potentiating Glucose-Stimulated Insulin Secretion in Human Islets
      You have access
      GPR40-Mediated Gα12 Activation by Allosteric Full Agonists Highly Efficacious at Potentiating Glucose-Stimulated Insulin Secretion in Human Islets
      Marie-Laure Rives, Brian Rady, Nadia Swanson, Shuyuan Zhao, Jenson Qi, Eric Arnoult, Ivona Bakaj, Arturo Mancini, Billy Breton, S. Paul Lee, Mark R. Player and Alessandro Pocai
      Molecular Pharmacology June 2018, 93 (6) 581-591; DOI: https://doi.org/10.1124/mol.117.111369

B

  1. Bak, Ellen

    1. You have access
      Ionotropic and Metabotropic Mechanisms of Allosteric Modulation of α7 Nicotinic Receptor Intracellular Calcium
      Justin R. King, Aman Ullah, Ellen Bak, M. Saleet Jafri and Nadine Kabbani
      Molecular Pharmacology June 2018, 93 (6) 601-611; DOI: https://doi.org/10.1124/mol.117.111401
  2. Bakaj, Ivona

    1. GPR40-Mediated G<em>α</em>12 Activation by Allosteric Full Agonists Highly Efficacious at Potentiating Glucose-Stimulated Insulin Secretion in Human Islets
      You have access
      GPR40-Mediated Gα12 Activation by Allosteric Full Agonists Highly Efficacious at Potentiating Glucose-Stimulated Insulin Secretion in Human Islets
      Marie-Laure Rives, Brian Rady, Nadia Swanson, Shuyuan Zhao, Jenson Qi, Eric Arnoult, Ivona Bakaj, Arturo Mancini, Billy Breton, S. Paul Lee, Mark R. Player and Alessandro Pocai
      Molecular Pharmacology June 2018, 93 (6) 581-591; DOI: https://doi.org/10.1124/mol.117.111369
  3. Bartonkova, Iveta

    1. You have access
      Methylindoles and Methoxyindoles are Agonists and Antagonists of Human Aryl Hydrocarbon Receptor
      Martina Stepankova, Iveta Bartonkova, Eva Jiskrova, Radim Vrzal, Sridhar Mani, Sandhya Kortagere and Zdenek Dvorak
      Molecular Pharmacology June 2018, 93 (6) 631-644; DOI: https://doi.org/10.1124/mol.118.112151
  4. Bear, Christine E.

    1. You have access
      Correctors of the Major Cystic Fibrosis Mutant Interact through Membrane-Spanning Domains
      Onofrio Laselva, Steven Molinski, Valeria Casavola and Christine E. Bear
      Molecular Pharmacology June 2018, 93 (6) 612-618; DOI: https://doi.org/10.1124/mol.118.111799
  5. Bradley, Sophie J.

    1. Open Access
      Bitopic Binding Mode of an M1 Muscarinic Acetylcholine Receptor Agonist Associated with Adverse Clinical Trial Outcomes
      Sophie J. Bradley, Colin Molloy, Christoffer Bundgaard, Adrian J. Mogg, Karen J. Thompson, Louis Dwomoh, Helen E. Sanger, Michael D. Crabtree, Simon M. Brooke, Patrick M. Sexton, Christian C. Felder, Arthur Christopoulos, Lisa M. Broad, Andrew B. Tobin and Christopher J. Langmead
      Molecular Pharmacology June 2018, 93 (6) 645-656; DOI: https://doi.org/10.1124/mol.118.111872
  6. Breton, Billy

    1. GPR40-Mediated G<em>α</em>12 Activation by Allosteric Full Agonists Highly Efficacious at Potentiating Glucose-Stimulated Insulin Secretion in Human Islets
      You have access
      GPR40-Mediated Gα12 Activation by Allosteric Full Agonists Highly Efficacious at Potentiating Glucose-Stimulated Insulin Secretion in Human Islets
      Marie-Laure Rives, Brian Rady, Nadia Swanson, Shuyuan Zhao, Jenson Qi, Eric Arnoult, Ivona Bakaj, Arturo Mancini, Billy Breton, S. Paul Lee, Mark R. Player and Alessandro Pocai
      Molecular Pharmacology June 2018, 93 (6) 581-591; DOI: https://doi.org/10.1124/mol.117.111369
  7. Broad, Lisa M.

    1. Open Access
      Bitopic Binding Mode of an M1 Muscarinic Acetylcholine Receptor Agonist Associated with Adverse Clinical Trial Outcomes
      Sophie J. Bradley, Colin Molloy, Christoffer Bundgaard, Adrian J. Mogg, Karen J. Thompson, Louis Dwomoh, Helen E. Sanger, Michael D. Crabtree, Simon M. Brooke, Patrick M. Sexton, Christian C. Felder, Arthur Christopoulos, Lisa M. Broad, Andrew B. Tobin and Christopher J. Langmead
      Molecular Pharmacology June 2018, 93 (6) 645-656; DOI: https://doi.org/10.1124/mol.118.111872
  8. Brooke, Simon M.

    1. Open Access
      Bitopic Binding Mode of an M1 Muscarinic Acetylcholine Receptor Agonist Associated with Adverse Clinical Trial Outcomes
      Sophie J. Bradley, Colin Molloy, Christoffer Bundgaard, Adrian J. Mogg, Karen J. Thompson, Louis Dwomoh, Helen E. Sanger, Michael D. Crabtree, Simon M. Brooke, Patrick M. Sexton, Christian C. Felder, Arthur Christopoulos, Lisa M. Broad, Andrew B. Tobin and Christopher J. Langmead
      Molecular Pharmacology June 2018, 93 (6) 645-656; DOI: https://doi.org/10.1124/mol.118.111872
  9. Bundgaard, Christoffer

    1. Open Access
      Bitopic Binding Mode of an M1 Muscarinic Acetylcholine Receptor Agonist Associated with Adverse Clinical Trial Outcomes
      Sophie J. Bradley, Colin Molloy, Christoffer Bundgaard, Adrian J. Mogg, Karen J. Thompson, Louis Dwomoh, Helen E. Sanger, Michael D. Crabtree, Simon M. Brooke, Patrick M. Sexton, Christian C. Felder, Arthur Christopoulos, Lisa M. Broad, Andrew B. Tobin and Christopher J. Langmead
      Molecular Pharmacology June 2018, 93 (6) 645-656; DOI: https://doi.org/10.1124/mol.118.111872

C

  1. Casavola, Valeria

    1. You have access
      Correctors of the Major Cystic Fibrosis Mutant Interact through Membrane-Spanning Domains
      Onofrio Laselva, Steven Molinski, Valeria Casavola and Christine E. Bear
      Molecular Pharmacology June 2018, 93 (6) 612-618; DOI: https://doi.org/10.1124/mol.118.111799
  2. Christopoulos, Arthur

    1. You have access
      Identification of Global and Ligand-Specific Calcium Sensing Receptor Activation Mechanisms
      Andrew N. Keller, Irina Kufareva, Tracy M. Josephs, Jiayin Diao, Vyvyan T. Mai, Arthur D. Conigrave, Arthur Christopoulos, Karen J. Gregory and Katie Leach
      Molecular Pharmacology June 2018, 93 (6) 619-630; DOI: https://doi.org/10.1124/mol.118.112086
    2. Open Access
      Bitopic Binding Mode of an M1 Muscarinic Acetylcholine Receptor Agonist Associated with Adverse Clinical Trial Outcomes
      Sophie J. Bradley, Colin Molloy, Christoffer Bundgaard, Adrian J. Mogg, Karen J. Thompson, Louis Dwomoh, Helen E. Sanger, Michael D. Crabtree, Simon M. Brooke, Patrick M. Sexton, Christian C. Felder, Arthur Christopoulos, Lisa M. Broad, Andrew B. Tobin and Christopher J. Langmead
      Molecular Pharmacology June 2018, 93 (6) 645-656; DOI: https://doi.org/10.1124/mol.118.111872
  3. Conigrave, Arthur D.

    1. You have access
      Identification of Global and Ligand-Specific Calcium Sensing Receptor Activation Mechanisms
      Andrew N. Keller, Irina Kufareva, Tracy M. Josephs, Jiayin Diao, Vyvyan T. Mai, Arthur D. Conigrave, Arthur Christopoulos, Karen J. Gregory and Katie Leach
      Molecular Pharmacology June 2018, 93 (6) 619-630; DOI: https://doi.org/10.1124/mol.118.112086
  4. Crabtree, Michael D.

    1. Open Access
      Bitopic Binding Mode of an M1 Muscarinic Acetylcholine Receptor Agonist Associated with Adverse Clinical Trial Outcomes
      Sophie J. Bradley, Colin Molloy, Christoffer Bundgaard, Adrian J. Mogg, Karen J. Thompson, Louis Dwomoh, Helen E. Sanger, Michael D. Crabtree, Simon M. Brooke, Patrick M. Sexton, Christian C. Felder, Arthur Christopoulos, Lisa M. Broad, Andrew B. Tobin and Christopher J. Langmead
      Molecular Pharmacology June 2018, 93 (6) 645-656; DOI: https://doi.org/10.1124/mol.118.111872

D

  1. Diao, Jiayin

    1. You have access
      Identification of Global and Ligand-Specific Calcium Sensing Receptor Activation Mechanisms
      Andrew N. Keller, Irina Kufareva, Tracy M. Josephs, Jiayin Diao, Vyvyan T. Mai, Arthur D. Conigrave, Arthur Christopoulos, Karen J. Gregory and Katie Leach
      Molecular Pharmacology June 2018, 93 (6) 619-630; DOI: https://doi.org/10.1124/mol.118.112086
  2. Dvorak, Zdenek

    1. You have access
      Methylindoles and Methoxyindoles are Agonists and Antagonists of Human Aryl Hydrocarbon Receptor
      Martina Stepankova, Iveta Bartonkova, Eva Jiskrova, Radim Vrzal, Sridhar Mani, Sandhya Kortagere and Zdenek Dvorak
      Molecular Pharmacology June 2018, 93 (6) 631-644; DOI: https://doi.org/10.1124/mol.118.112151
  3. Dwomoh, Louis

    1. Open Access
      Bitopic Binding Mode of an M1 Muscarinic Acetylcholine Receptor Agonist Associated with Adverse Clinical Trial Outcomes
      Sophie J. Bradley, Colin Molloy, Christoffer Bundgaard, Adrian J. Mogg, Karen J. Thompson, Louis Dwomoh, Helen E. Sanger, Michael D. Crabtree, Simon M. Brooke, Patrick M. Sexton, Christian C. Felder, Arthur Christopoulos, Lisa M. Broad, Andrew B. Tobin and Christopher J. Langmead
      Molecular Pharmacology June 2018, 93 (6) 645-656; DOI: https://doi.org/10.1124/mol.118.111872

F

  1. Felder, Christian C.

    1. Open Access
      Bitopic Binding Mode of an M1 Muscarinic Acetylcholine Receptor Agonist Associated with Adverse Clinical Trial Outcomes
      Sophie J. Bradley, Colin Molloy, Christoffer Bundgaard, Adrian J. Mogg, Karen J. Thompson, Louis Dwomoh, Helen E. Sanger, Michael D. Crabtree, Simon M. Brooke, Patrick M. Sexton, Christian C. Felder, Arthur Christopoulos, Lisa M. Broad, Andrew B. Tobin and Christopher J. Langmead
      Molecular Pharmacology June 2018, 93 (6) 645-656; DOI: https://doi.org/10.1124/mol.118.111872

G

  1. Gregory, Karen J.

    1. You have access
      Identification of Global and Ligand-Specific Calcium Sensing Receptor Activation Mechanisms
      Andrew N. Keller, Irina Kufareva, Tracy M. Josephs, Jiayin Diao, Vyvyan T. Mai, Arthur D. Conigrave, Arthur Christopoulos, Karen J. Gregory and Katie Leach
      Molecular Pharmacology June 2018, 93 (6) 619-630; DOI: https://doi.org/10.1124/mol.118.112086

H

  1. Huang, Zili

    1. You have access
      Thermoregulation-Independent Regulation of Sleep by Serotonin Revealed in Mice Defective in Serotonin Synthesis
      Xian Zhang, Hongming Yan, Yanjia Luo, Zili Huang and Yi Rao
      Molecular Pharmacology June 2018, 93 (6) 657-664; DOI: https://doi.org/10.1124/mol.117.111229

I

  1. Inanobe, Atsushi

    1. Open Access
      Kir Channel Blockages by Proflavine Derivatives via Multiple Modes of Interaction
      Atsushi Inanobe, Hideaki Itamochi and Yoshihisa Kurachi
      Molecular Pharmacology June 2018, 93 (6) 592-600; DOI: https://doi.org/10.1124/mol.117.111377
  2. Itamochi, Hideaki

    1. Open Access
      Kir Channel Blockages by Proflavine Derivatives via Multiple Modes of Interaction
      Atsushi Inanobe, Hideaki Itamochi and Yoshihisa Kurachi
      Molecular Pharmacology June 2018, 93 (6) 592-600; DOI: https://doi.org/10.1124/mol.117.111377

J

  1. Jafri, M. Saleet

    1. You have access
      Ionotropic and Metabotropic Mechanisms of Allosteric Modulation of α7 Nicotinic Receptor Intracellular Calcium
      Justin R. King, Aman Ullah, Ellen Bak, M. Saleet Jafri and Nadine Kabbani
      Molecular Pharmacology June 2018, 93 (6) 601-611; DOI: https://doi.org/10.1124/mol.117.111401
  2. Jiskrova, Eva

    1. You have access
      Methylindoles and Methoxyindoles are Agonists and Antagonists of Human Aryl Hydrocarbon Receptor
      Martina Stepankova, Iveta Bartonkova, Eva Jiskrova, Radim Vrzal, Sridhar Mani, Sandhya Kortagere and Zdenek Dvorak
      Molecular Pharmacology June 2018, 93 (6) 631-644; DOI: https://doi.org/10.1124/mol.118.112151
  3. Josephs, Tracy M.

    1. You have access
      Identification of Global and Ligand-Specific Calcium Sensing Receptor Activation Mechanisms
      Andrew N. Keller, Irina Kufareva, Tracy M. Josephs, Jiayin Diao, Vyvyan T. Mai, Arthur D. Conigrave, Arthur Christopoulos, Karen J. Gregory and Katie Leach
      Molecular Pharmacology June 2018, 93 (6) 619-630; DOI: https://doi.org/10.1124/mol.118.112086

K

  1. Kabbani, Nadine

    1. You have access
      Ionotropic and Metabotropic Mechanisms of Allosteric Modulation of α7 Nicotinic Receptor Intracellular Calcium
      Justin R. King, Aman Ullah, Ellen Bak, M. Saleet Jafri and Nadine Kabbani
      Molecular Pharmacology June 2018, 93 (6) 601-611; DOI: https://doi.org/10.1124/mol.117.111401
  2. Keller, Andrew N.

    1. You have access
      Identification of Global and Ligand-Specific Calcium Sensing Receptor Activation Mechanisms
      Andrew N. Keller, Irina Kufareva, Tracy M. Josephs, Jiayin Diao, Vyvyan T. Mai, Arthur D. Conigrave, Arthur Christopoulos, Karen J. Gregory and Katie Leach
      Molecular Pharmacology June 2018, 93 (6) 619-630; DOI: https://doi.org/10.1124/mol.118.112086
  3. King, Justin R.

    1. You have access
      Ionotropic and Metabotropic Mechanisms of Allosteric Modulation of α7 Nicotinic Receptor Intracellular Calcium
      Justin R. King, Aman Ullah, Ellen Bak, M. Saleet Jafri and Nadine Kabbani
      Molecular Pharmacology June 2018, 93 (6) 601-611; DOI: https://doi.org/10.1124/mol.117.111401
  4. Kortagere, Sandhya

    1. You have access
      Methylindoles and Methoxyindoles are Agonists and Antagonists of Human Aryl Hydrocarbon Receptor
      Martina Stepankova, Iveta Bartonkova, Eva Jiskrova, Radim Vrzal, Sridhar Mani, Sandhya Kortagere and Zdenek Dvorak
      Molecular Pharmacology June 2018, 93 (6) 631-644; DOI: https://doi.org/10.1124/mol.118.112151
  5. Kufareva, Irina

    1. You have access
      Identification of Global and Ligand-Specific Calcium Sensing Receptor Activation Mechanisms
      Andrew N. Keller, Irina Kufareva, Tracy M. Josephs, Jiayin Diao, Vyvyan T. Mai, Arthur D. Conigrave, Arthur Christopoulos, Karen J. Gregory and Katie Leach
      Molecular Pharmacology June 2018, 93 (6) 619-630; DOI: https://doi.org/10.1124/mol.118.112086
  6. Kurachi, Yoshihisa

    1. Open Access
      Kir Channel Blockages by Proflavine Derivatives via Multiple Modes of Interaction
      Atsushi Inanobe, Hideaki Itamochi and Yoshihisa Kurachi
      Molecular Pharmacology June 2018, 93 (6) 592-600; DOI: https://doi.org/10.1124/mol.117.111377

L

  1. Langmead, Christopher J.

    1. Open Access
      Bitopic Binding Mode of an M1 Muscarinic Acetylcholine Receptor Agonist Associated with Adverse Clinical Trial Outcomes
      Sophie J. Bradley, Colin Molloy, Christoffer Bundgaard, Adrian J. Mogg, Karen J. Thompson, Louis Dwomoh, Helen E. Sanger, Michael D. Crabtree, Simon M. Brooke, Patrick M. Sexton, Christian C. Felder, Arthur Christopoulos, Lisa M. Broad, Andrew B. Tobin and Christopher J. Langmead
      Molecular Pharmacology June 2018, 93 (6) 645-656; DOI: https://doi.org/10.1124/mol.118.111872
  2. Laselva, Onofrio

    1. You have access
      Correctors of the Major Cystic Fibrosis Mutant Interact through Membrane-Spanning Domains
      Onofrio Laselva, Steven Molinski, Valeria Casavola and Christine E. Bear
      Molecular Pharmacology June 2018, 93 (6) 612-618; DOI: https://doi.org/10.1124/mol.118.111799
  3. Leach, Katie

    1. You have access
      Identification of Global and Ligand-Specific Calcium Sensing Receptor Activation Mechanisms
      Andrew N. Keller, Irina Kufareva, Tracy M. Josephs, Jiayin Diao, Vyvyan T. Mai, Arthur D. Conigrave, Arthur Christopoulos, Karen J. Gregory and Katie Leach
      Molecular Pharmacology June 2018, 93 (6) 619-630; DOI: https://doi.org/10.1124/mol.118.112086
  4. Lee, S. Paul

    1. GPR40-Mediated G<em>α</em>12 Activation by Allosteric Full Agonists Highly Efficacious at Potentiating Glucose-Stimulated Insulin Secretion in Human Islets
      You have access
      GPR40-Mediated Gα12 Activation by Allosteric Full Agonists Highly Efficacious at Potentiating Glucose-Stimulated Insulin Secretion in Human Islets
      Marie-Laure Rives, Brian Rady, Nadia Swanson, Shuyuan Zhao, Jenson Qi, Eric Arnoult, Ivona Bakaj, Arturo Mancini, Billy Breton, S. Paul Lee, Mark R. Player and Alessandro Pocai
      Molecular Pharmacology June 2018, 93 (6) 581-591; DOI: https://doi.org/10.1124/mol.117.111369
  5. Lin, Yunfei

    1. You have access
      Leflunomide Increases Hepatic Exposure to Methotrexate and Its Metabolite by Differentially Regulating Multidrug Resistance–Associated Protein Mrp2/3/4 Transporters via Peroxisome Proliferator–Activated Receptor α Activation
      Le Wang, Leilei Ma, Yunfei Lin, Xing Liu, Ling Xiao, Yiting Zhang, Ye Xu, Hu Zhou and Guoyu Pan
      Molecular Pharmacology June 2018, 93 (6) 563-574; DOI: https://doi.org/10.1124/mol.117.110593
  6. Liu, Xing

    1. You have access
      Leflunomide Increases Hepatic Exposure to Methotrexate and Its Metabolite by Differentially Regulating Multidrug Resistance–Associated Protein Mrp2/3/4 Transporters via Peroxisome Proliferator–Activated Receptor α Activation
      Le Wang, Leilei Ma, Yunfei Lin, Xing Liu, Ling Xiao, Yiting Zhang, Ye Xu, Hu Zhou and Guoyu Pan
      Molecular Pharmacology June 2018, 93 (6) 563-574; DOI: https://doi.org/10.1124/mol.117.110593
  7. Luo, Yanjia

    1. You have access
      Thermoregulation-Independent Regulation of Sleep by Serotonin Revealed in Mice Defective in Serotonin Synthesis
      Xian Zhang, Hongming Yan, Yanjia Luo, Zili Huang and Yi Rao
      Molecular Pharmacology June 2018, 93 (6) 657-664; DOI: https://doi.org/10.1124/mol.117.111229

M

  1. Ma, Leilei

    1. You have access
      Leflunomide Increases Hepatic Exposure to Methotrexate and Its Metabolite by Differentially Regulating Multidrug Resistance–Associated Protein Mrp2/3/4 Transporters via Peroxisome Proliferator–Activated Receptor α Activation
      Le Wang, Leilei Ma, Yunfei Lin, Xing Liu, Ling Xiao, Yiting Zhang, Ye Xu, Hu Zhou and Guoyu Pan
      Molecular Pharmacology June 2018, 93 (6) 563-574; DOI: https://doi.org/10.1124/mol.117.110593
  2. Mai, Vyvyan T.

    1. You have access
      Identification of Global and Ligand-Specific Calcium Sensing Receptor Activation Mechanisms
      Andrew N. Keller, Irina Kufareva, Tracy M. Josephs, Jiayin Diao, Vyvyan T. Mai, Arthur D. Conigrave, Arthur Christopoulos, Karen J. Gregory and Katie Leach
      Molecular Pharmacology June 2018, 93 (6) 619-630; DOI: https://doi.org/10.1124/mol.118.112086
  3. Mancini, Arturo

    1. GPR40-Mediated G<em>α</em>12 Activation by Allosteric Full Agonists Highly Efficacious at Potentiating Glucose-Stimulated Insulin Secretion in Human Islets
      You have access
      GPR40-Mediated Gα12 Activation by Allosteric Full Agonists Highly Efficacious at Potentiating Glucose-Stimulated Insulin Secretion in Human Islets
      Marie-Laure Rives, Brian Rady, Nadia Swanson, Shuyuan Zhao, Jenson Qi, Eric Arnoult, Ivona Bakaj, Arturo Mancini, Billy Breton, S. Paul Lee, Mark R. Player and Alessandro Pocai
      Molecular Pharmacology June 2018, 93 (6) 581-591; DOI: https://doi.org/10.1124/mol.117.111369
  4. Mani, Sridhar

    1. You have access
      Methylindoles and Methoxyindoles are Agonists and Antagonists of Human Aryl Hydrocarbon Receptor
      Martina Stepankova, Iveta Bartonkova, Eva Jiskrova, Radim Vrzal, Sridhar Mani, Sandhya Kortagere and Zdenek Dvorak
      Molecular Pharmacology June 2018, 93 (6) 631-644; DOI: https://doi.org/10.1124/mol.118.112151
  5. Mogg, Adrian J.

    1. Open Access
      Bitopic Binding Mode of an M1 Muscarinic Acetylcholine Receptor Agonist Associated with Adverse Clinical Trial Outcomes
      Sophie J. Bradley, Colin Molloy, Christoffer Bundgaard, Adrian J. Mogg, Karen J. Thompson, Louis Dwomoh, Helen E. Sanger, Michael D. Crabtree, Simon M. Brooke, Patrick M. Sexton, Christian C. Felder, Arthur Christopoulos, Lisa M. Broad, Andrew B. Tobin and Christopher J. Langmead
      Molecular Pharmacology June 2018, 93 (6) 645-656; DOI: https://doi.org/10.1124/mol.118.111872
  6. Molinski, Steven

    1. You have access
      Correctors of the Major Cystic Fibrosis Mutant Interact through Membrane-Spanning Domains
      Onofrio Laselva, Steven Molinski, Valeria Casavola and Christine E. Bear
      Molecular Pharmacology June 2018, 93 (6) 612-618; DOI: https://doi.org/10.1124/mol.118.111799
  7. Molloy, Colin

    1. Open Access
      Bitopic Binding Mode of an M1 Muscarinic Acetylcholine Receptor Agonist Associated with Adverse Clinical Trial Outcomes
      Sophie J. Bradley, Colin Molloy, Christoffer Bundgaard, Adrian J. Mogg, Karen J. Thompson, Louis Dwomoh, Helen E. Sanger, Michael D. Crabtree, Simon M. Brooke, Patrick M. Sexton, Christian C. Felder, Arthur Christopoulos, Lisa M. Broad, Andrew B. Tobin and Christopher J. Langmead
      Molecular Pharmacology June 2018, 93 (6) 645-656; DOI: https://doi.org/10.1124/mol.118.111872

P

  1. Pan, Guoyu

    1. You have access
      Leflunomide Increases Hepatic Exposure to Methotrexate and Its Metabolite by Differentially Regulating Multidrug Resistance–Associated Protein Mrp2/3/4 Transporters via Peroxisome Proliferator–Activated Receptor α Activation
      Le Wang, Leilei Ma, Yunfei Lin, Xing Liu, Ling Xiao, Yiting Zhang, Ye Xu, Hu Zhou and Guoyu Pan
      Molecular Pharmacology June 2018, 93 (6) 563-574; DOI: https://doi.org/10.1124/mol.117.110593
  2. Perron, Michael

    1. You have access
      Inhibition of CD45 Phosphatase Activity Induces Cell Cycle Arrest and Apoptosis of CD45+ Lymphoid Tumors Ex Vivo and In Vivo
      Michael Perron and H. Uri Saragovi
      Molecular Pharmacology June 2018, 93 (6) 575-580; DOI: https://doi.org/10.1124/mol.117.110908
  3. Player, Mark R.

    1. GPR40-Mediated G<em>α</em>12 Activation by Allosteric Full Agonists Highly Efficacious at Potentiating Glucose-Stimulated Insulin Secretion in Human Islets
      You have access
      GPR40-Mediated Gα12 Activation by Allosteric Full Agonists Highly Efficacious at Potentiating Glucose-Stimulated Insulin Secretion in Human Islets
      Marie-Laure Rives, Brian Rady, Nadia Swanson, Shuyuan Zhao, Jenson Qi, Eric Arnoult, Ivona Bakaj, Arturo Mancini, Billy Breton, S. Paul Lee, Mark R. Player and Alessandro Pocai
      Molecular Pharmacology June 2018, 93 (6) 581-591; DOI: https://doi.org/10.1124/mol.117.111369
  4. Pocai, Alessandro

    1. GPR40-Mediated G<em>α</em>12 Activation by Allosteric Full Agonists Highly Efficacious at Potentiating Glucose-Stimulated Insulin Secretion in Human Islets
      You have access
      GPR40-Mediated Gα12 Activation by Allosteric Full Agonists Highly Efficacious at Potentiating Glucose-Stimulated Insulin Secretion in Human Islets
      Marie-Laure Rives, Brian Rady, Nadia Swanson, Shuyuan Zhao, Jenson Qi, Eric Arnoult, Ivona Bakaj, Arturo Mancini, Billy Breton, S. Paul Lee, Mark R. Player and Alessandro Pocai
      Molecular Pharmacology June 2018, 93 (6) 581-591; DOI: https://doi.org/10.1124/mol.117.111369

Q

  1. Qi, Jenson

    1. GPR40-Mediated G<em>α</em>12 Activation by Allosteric Full Agonists Highly Efficacious at Potentiating Glucose-Stimulated Insulin Secretion in Human Islets
      You have access
      GPR40-Mediated Gα12 Activation by Allosteric Full Agonists Highly Efficacious at Potentiating Glucose-Stimulated Insulin Secretion in Human Islets
      Marie-Laure Rives, Brian Rady, Nadia Swanson, Shuyuan Zhao, Jenson Qi, Eric Arnoult, Ivona Bakaj, Arturo Mancini, Billy Breton, S. Paul Lee, Mark R. Player and Alessandro Pocai
      Molecular Pharmacology June 2018, 93 (6) 581-591; DOI: https://doi.org/10.1124/mol.117.111369

R

  1. Rady, Brian

    1. GPR40-Mediated G<em>α</em>12 Activation by Allosteric Full Agonists Highly Efficacious at Potentiating Glucose-Stimulated Insulin Secretion in Human Islets
      You have access
      GPR40-Mediated Gα12 Activation by Allosteric Full Agonists Highly Efficacious at Potentiating Glucose-Stimulated Insulin Secretion in Human Islets
      Marie-Laure Rives, Brian Rady, Nadia Swanson, Shuyuan Zhao, Jenson Qi, Eric Arnoult, Ivona Bakaj, Arturo Mancini, Billy Breton, S. Paul Lee, Mark R. Player and Alessandro Pocai
      Molecular Pharmacology June 2018, 93 (6) 581-591; DOI: https://doi.org/10.1124/mol.117.111369
  2. Rao, Yi

    1. You have access
      Thermoregulation-Independent Regulation of Sleep by Serotonin Revealed in Mice Defective in Serotonin Synthesis
      Xian Zhang, Hongming Yan, Yanjia Luo, Zili Huang and Yi Rao
      Molecular Pharmacology June 2018, 93 (6) 657-664; DOI: https://doi.org/10.1124/mol.117.111229
  3. Rives, Marie-Laure

    1. GPR40-Mediated G<em>α</em>12 Activation by Allosteric Full Agonists Highly Efficacious at Potentiating Glucose-Stimulated Insulin Secretion in Human Islets
      You have access
      GPR40-Mediated Gα12 Activation by Allosteric Full Agonists Highly Efficacious at Potentiating Glucose-Stimulated Insulin Secretion in Human Islets
      Marie-Laure Rives, Brian Rady, Nadia Swanson, Shuyuan Zhao, Jenson Qi, Eric Arnoult, Ivona Bakaj, Arturo Mancini, Billy Breton, S. Paul Lee, Mark R. Player and Alessandro Pocai
      Molecular Pharmacology June 2018, 93 (6) 581-591; DOI: https://doi.org/10.1124/mol.117.111369

S

  1. Sanger, Helen E.

    1. Open Access
      Bitopic Binding Mode of an M1 Muscarinic Acetylcholine Receptor Agonist Associated with Adverse Clinical Trial Outcomes
      Sophie J. Bradley, Colin Molloy, Christoffer Bundgaard, Adrian J. Mogg, Karen J. Thompson, Louis Dwomoh, Helen E. Sanger, Michael D. Crabtree, Simon M. Brooke, Patrick M. Sexton, Christian C. Felder, Arthur Christopoulos, Lisa M. Broad, Andrew B. Tobin and Christopher J. Langmead
      Molecular Pharmacology June 2018, 93 (6) 645-656; DOI: https://doi.org/10.1124/mol.118.111872
  2. Saragovi, H. Uri

    1. You have access
      Inhibition of CD45 Phosphatase Activity Induces Cell Cycle Arrest and Apoptosis of CD45+ Lymphoid Tumors Ex Vivo and In Vivo
      Michael Perron and H. Uri Saragovi
      Molecular Pharmacology June 2018, 93 (6) 575-580; DOI: https://doi.org/10.1124/mol.117.110908
  3. Sexton, Patrick M.

    1. Open Access
      Bitopic Binding Mode of an M1 Muscarinic Acetylcholine Receptor Agonist Associated with Adverse Clinical Trial Outcomes
      Sophie J. Bradley, Colin Molloy, Christoffer Bundgaard, Adrian J. Mogg, Karen J. Thompson, Louis Dwomoh, Helen E. Sanger, Michael D. Crabtree, Simon M. Brooke, Patrick M. Sexton, Christian C. Felder, Arthur Christopoulos, Lisa M. Broad, Andrew B. Tobin and Christopher J. Langmead
      Molecular Pharmacology June 2018, 93 (6) 645-656; DOI: https://doi.org/10.1124/mol.118.111872
  4. Stepankova, Martina

    1. You have access
      Methylindoles and Methoxyindoles are Agonists and Antagonists of Human Aryl Hydrocarbon Receptor
      Martina Stepankova, Iveta Bartonkova, Eva Jiskrova, Radim Vrzal, Sridhar Mani, Sandhya Kortagere and Zdenek Dvorak
      Molecular Pharmacology June 2018, 93 (6) 631-644; DOI: https://doi.org/10.1124/mol.118.112151
  5. Swanson, Nadia

    1. GPR40-Mediated G<em>α</em>12 Activation by Allosteric Full Agonists Highly Efficacious at Potentiating Glucose-Stimulated Insulin Secretion in Human Islets
      You have access
      GPR40-Mediated Gα12 Activation by Allosteric Full Agonists Highly Efficacious at Potentiating Glucose-Stimulated Insulin Secretion in Human Islets
      Marie-Laure Rives, Brian Rady, Nadia Swanson, Shuyuan Zhao, Jenson Qi, Eric Arnoult, Ivona Bakaj, Arturo Mancini, Billy Breton, S. Paul Lee, Mark R. Player and Alessandro Pocai
      Molecular Pharmacology June 2018, 93 (6) 581-591; DOI: https://doi.org/10.1124/mol.117.111369

T

  1. Thompson, Karen J.

    1. Open Access
      Bitopic Binding Mode of an M1 Muscarinic Acetylcholine Receptor Agonist Associated with Adverse Clinical Trial Outcomes
      Sophie J. Bradley, Colin Molloy, Christoffer Bundgaard, Adrian J. Mogg, Karen J. Thompson, Louis Dwomoh, Helen E. Sanger, Michael D. Crabtree, Simon M. Brooke, Patrick M. Sexton, Christian C. Felder, Arthur Christopoulos, Lisa M. Broad, Andrew B. Tobin and Christopher J. Langmead
      Molecular Pharmacology June 2018, 93 (6) 645-656; DOI: https://doi.org/10.1124/mol.118.111872
  2. Tobin, Andrew B.

    1. Open Access
      Bitopic Binding Mode of an M1 Muscarinic Acetylcholine Receptor Agonist Associated with Adverse Clinical Trial Outcomes
      Sophie J. Bradley, Colin Molloy, Christoffer Bundgaard, Adrian J. Mogg, Karen J. Thompson, Louis Dwomoh, Helen E. Sanger, Michael D. Crabtree, Simon M. Brooke, Patrick M. Sexton, Christian C. Felder, Arthur Christopoulos, Lisa M. Broad, Andrew B. Tobin and Christopher J. Langmead
      Molecular Pharmacology June 2018, 93 (6) 645-656; DOI: https://doi.org/10.1124/mol.118.111872

U

  1. Ullah, Aman

    1. You have access
      Ionotropic and Metabotropic Mechanisms of Allosteric Modulation of α7 Nicotinic Receptor Intracellular Calcium
      Justin R. King, Aman Ullah, Ellen Bak, M. Saleet Jafri and Nadine Kabbani
      Molecular Pharmacology June 2018, 93 (6) 601-611; DOI: https://doi.org/10.1124/mol.117.111401

V

  1. Vrzal, Radim

    1. You have access
      Methylindoles and Methoxyindoles are Agonists and Antagonists of Human Aryl Hydrocarbon Receptor
      Martina Stepankova, Iveta Bartonkova, Eva Jiskrova, Radim Vrzal, Sridhar Mani, Sandhya Kortagere and Zdenek Dvorak
      Molecular Pharmacology June 2018, 93 (6) 631-644; DOI: https://doi.org/10.1124/mol.118.112151

W

  1. Wang, Le

    1. You have access
      Leflunomide Increases Hepatic Exposure to Methotrexate and Its Metabolite by Differentially Regulating Multidrug Resistance–Associated Protein Mrp2/3/4 Transporters via Peroxisome Proliferator–Activated Receptor α Activation
      Le Wang, Leilei Ma, Yunfei Lin, Xing Liu, Ling Xiao, Yiting Zhang, Ye Xu, Hu Zhou and Guoyu Pan
      Molecular Pharmacology June 2018, 93 (6) 563-574; DOI: https://doi.org/10.1124/mol.117.110593

X

  1. Xiao, Ling

    1. You have access
      Leflunomide Increases Hepatic Exposure to Methotrexate and Its Metabolite by Differentially Regulating Multidrug Resistance–Associated Protein Mrp2/3/4 Transporters via Peroxisome Proliferator–Activated Receptor α Activation
      Le Wang, Leilei Ma, Yunfei Lin, Xing Liu, Ling Xiao, Yiting Zhang, Ye Xu, Hu Zhou and Guoyu Pan
      Molecular Pharmacology June 2018, 93 (6) 563-574; DOI: https://doi.org/10.1124/mol.117.110593
  2. Xu, Ye

    1. You have access
      Leflunomide Increases Hepatic Exposure to Methotrexate and Its Metabolite by Differentially Regulating Multidrug Resistance–Associated Protein Mrp2/3/4 Transporters via Peroxisome Proliferator–Activated Receptor α Activation
      Le Wang, Leilei Ma, Yunfei Lin, Xing Liu, Ling Xiao, Yiting Zhang, Ye Xu, Hu Zhou and Guoyu Pan
      Molecular Pharmacology June 2018, 93 (6) 563-574; DOI: https://doi.org/10.1124/mol.117.110593

Y

  1. Yan, Hongming

    1. You have access
      Thermoregulation-Independent Regulation of Sleep by Serotonin Revealed in Mice Defective in Serotonin Synthesis
      Xian Zhang, Hongming Yan, Yanjia Luo, Zili Huang and Yi Rao
      Molecular Pharmacology June 2018, 93 (6) 657-664; DOI: https://doi.org/10.1124/mol.117.111229

Z

  1. Zhang, Xian

    1. You have access
      Thermoregulation-Independent Regulation of Sleep by Serotonin Revealed in Mice Defective in Serotonin Synthesis
      Xian Zhang, Hongming Yan, Yanjia Luo, Zili Huang and Yi Rao
      Molecular Pharmacology June 2018, 93 (6) 657-664; DOI: https://doi.org/10.1124/mol.117.111229
  2. Zhang, Yiting

    1. You have access
      Leflunomide Increases Hepatic Exposure to Methotrexate and Its Metabolite by Differentially Regulating Multidrug Resistance–Associated Protein Mrp2/3/4 Transporters via Peroxisome Proliferator–Activated Receptor α Activation
      Le Wang, Leilei Ma, Yunfei Lin, Xing Liu, Ling Xiao, Yiting Zhang, Ye Xu, Hu Zhou and Guoyu Pan
      Molecular Pharmacology June 2018, 93 (6) 563-574; DOI: https://doi.org/10.1124/mol.117.110593
  3. Zhao, Shuyuan

    1. GPR40-Mediated G<em>α</em>12 Activation by Allosteric Full Agonists Highly Efficacious at Potentiating Glucose-Stimulated Insulin Secretion in Human Islets
      You have access
      GPR40-Mediated Gα12 Activation by Allosteric Full Agonists Highly Efficacious at Potentiating Glucose-Stimulated Insulin Secretion in Human Islets
      Marie-Laure Rives, Brian Rady, Nadia Swanson, Shuyuan Zhao, Jenson Qi, Eric Arnoult, Ivona Bakaj, Arturo Mancini, Billy Breton, S. Paul Lee, Mark R. Player and Alessandro Pocai
      Molecular Pharmacology June 2018, 93 (6) 581-591; DOI: https://doi.org/10.1124/mol.117.111369
  4. Zhou, Hu

    1. You have access
      Leflunomide Increases Hepatic Exposure to Methotrexate and Its Metabolite by Differentially Regulating Multidrug Resistance–Associated Protein Mrp2/3/4 Transporters via Peroxisome Proliferator–Activated Receptor α Activation
      Le Wang, Leilei Ma, Yunfei Lin, Xing Liu, Ling Xiao, Yiting Zhang, Ye Xu, Hu Zhou and Guoyu Pan
      Molecular Pharmacology June 2018, 93 (6) 563-574; DOI: https://doi.org/10.1124/mol.117.110593
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Molecular Pharmacology: 93 (6)
Molecular Pharmacology
Vol. 93, Issue 6
1 Jun 2018
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  • SB-431542 Is a Potent and Specific Inhibitor of Transforming Growth Factor-β Superfamily Type I Activin Receptor-Like Kinase (ALK) Receptors ALK4, ALK5, and ALK7
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  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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