Research ArticleArticle
An Outward-Facing Aromatic Amino Acid Is Crucial for Signaling between the Membrane-Spanning and Nucleotide-Binding Domains of Multidrug Resistance Protein 1 (MRP1; ABCC1)
Kevin E. Weigl, Gwenaëlle Conseil, Alice J. Rothnie, May Arama, Yossi Tsfadia and Susan P. C. Cole
Molecular Pharmacology September 2018, 94 (3) 1069-1078; DOI: https://doi.org/10.1124/mol.118.112615
Kevin E. Weigl
Department of Pathology and Molecular Medicine (K.E.W., S.P.C.C.) and Division of Cancer Biology and Genetics (G.C., A.J.R., S.P.C.C.), Queen’s University Cancer Research Institute, Kingston, Ontario, Canada; and Department of Biochemistry and Molecular Biology, Tel Aviv University, Tel Aviv, Israel (M.A., Y.T.)
Gwenaëlle Conseil
Department of Pathology and Molecular Medicine (K.E.W., S.P.C.C.) and Division of Cancer Biology and Genetics (G.C., A.J.R., S.P.C.C.), Queen’s University Cancer Research Institute, Kingston, Ontario, Canada; and Department of Biochemistry and Molecular Biology, Tel Aviv University, Tel Aviv, Israel (M.A., Y.T.)
Alice J. Rothnie
Department of Pathology and Molecular Medicine (K.E.W., S.P.C.C.) and Division of Cancer Biology and Genetics (G.C., A.J.R., S.P.C.C.), Queen’s University Cancer Research Institute, Kingston, Ontario, Canada; and Department of Biochemistry and Molecular Biology, Tel Aviv University, Tel Aviv, Israel (M.A., Y.T.)
May Arama
Department of Pathology and Molecular Medicine (K.E.W., S.P.C.C.) and Division of Cancer Biology and Genetics (G.C., A.J.R., S.P.C.C.), Queen’s University Cancer Research Institute, Kingston, Ontario, Canada; and Department of Biochemistry and Molecular Biology, Tel Aviv University, Tel Aviv, Israel (M.A., Y.T.)
Yossi Tsfadia
Department of Pathology and Molecular Medicine (K.E.W., S.P.C.C.) and Division of Cancer Biology and Genetics (G.C., A.J.R., S.P.C.C.), Queen’s University Cancer Research Institute, Kingston, Ontario, Canada; and Department of Biochemistry and Molecular Biology, Tel Aviv University, Tel Aviv, Israel (M.A., Y.T.)
Susan P. C. Cole
Department of Pathology and Molecular Medicine (K.E.W., S.P.C.C.) and Division of Cancer Biology and Genetics (G.C., A.J.R., S.P.C.C.), Queen’s University Cancer Research Institute, Kingston, Ontario, Canada; and Department of Biochemistry and Molecular Biology, Tel Aviv University, Tel Aviv, Israel (M.A., Y.T.)
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Long-Range Signaling between Exofacial Phe and MRP1 NBDs
Kevin E. Weigl, Gwenaëlle Conseil, Alice J. Rothnie, May Arama, Yossi Tsfadia and Susan P. C. Cole
Molecular Pharmacology September 1, 2018, 94 (3) 1069-1078; DOI: https://doi.org/10.1124/mol.118.112615
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