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Molecular Pharmacology

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Table of Contents

April 01, 2019; Volume 95,Issue 4

Minireview

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    A Mechanism-Based Approach to P2X7 Receptor Action
    Mehmet Ugur and Özlem Ugur
    Molecular Pharmacology April 2019, 95 (4) 442-450; DOI: https://doi.org/10.1124/mol.118.115022

Articles

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    Derivatives of Piperazines as Potential Therapeutic Agents for Alzheimer’s Disease
    Elena Popugaeva, Daria Chernyuk, Hua Zhang, Tatyana Y. Postnikova, Karina Pats, Elena Fedorova, Vladimir Poroikov, Aleksey V. Zaitsev and Ilya Bezprozvanny
    Molecular Pharmacology April 2019, 95 (4) 337-348; DOI: https://doi.org/10.1124/mol.118.114348
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    Insights into the Regulatory Properties of Human Adenylyl Cyclase Type 9
    Tanya A. Baldwin, Yong Li, Cameron S. Brand, Val J. Watts and Carmen W. Dessauer
    Molecular Pharmacology April 2019, 95 (4) 349-360; DOI: https://doi.org/10.1124/mol.118.114595
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    Statins Perturb Gβγ Signaling and Cell Behavior in a Gγ Subtype Dependent Manner
    Mithila Tennakoon, Dinesh Kankanamge, Kanishka Senarath, Zehra Fasih and Ajith Karunarathne
    Molecular Pharmacology April 2019, 95 (4) 361-375; DOI: https://doi.org/10.1124/mol.118.114710
  • A Comparison of the Ability of Leu<sup>8</sup>- and Pro<sup>8</sup>-Oxytocin to Regulate Intracellular Ca<sup>2+</sup> and Ca<sup>2+</sup>-Activated K<sup>+</sup> Channels at Human and Marmoset Oxytocin Receptors
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    A Comparison of the Ability of Leu8- and Pro8-Oxytocin to Regulate Intracellular Ca2+ and Ca2+-Activated K+ Channels at Human and Marmoset Oxytocin Receptors
    Marsha L. Pierce, Suneet Mehrotra, Aaryn C. Mustoe, Jeffrey A. French and Thomas F. Murray
    Molecular Pharmacology April 2019, 95 (4) 376-385; DOI: https://doi.org/10.1124/mol.118.114744
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    Blockade of the Human Ether A-Go-Go–Related Gene (hERG) Potassium Channel by Fentanyl
    Jared N. Tschirhart, Wentao Li, Jun Guo and Shetuan Zhang
    Molecular Pharmacology April 2019, 95 (4) 386-397; DOI: https://doi.org/10.1124/mol.118.114751
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    Chronic Menthol Does Not Change Stoichiometry or Functional Plasma Membrane Levels of Mouse α3β4-Containing Nicotinic Acetylcholine Receptors
    Selvan Bavan, Charlene H. Kim, Brandon J. Henderson and Henry A. Lester
    Molecular Pharmacology April 2019, 95 (4) 398-407; DOI: https://doi.org/10.1124/mol.118.114769
  • Monod-Wyman-Changeux Allosteric Shift Analysis in Mutant <em>α</em>1<em>β</em>3<em>γ</em>2L GABA<sub>A</sub> Receptors Indicates Selectivity and Crosstalk among Intersubunit Transmembrane Anesthetic Sites
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    Monod-Wyman-Changeux Allosteric Shift Analysis in Mutant α1β3γ2L GABAA Receptors Indicates Selectivity and Crosstalk among Intersubunit Transmembrane Anesthetic Sites
    Andrea Szabo, Anahita Nourmahnad, Elizabeth Halpin and Stuart A. Forman
    Molecular Pharmacology April 2019, 95 (4) 408-417; DOI: https://doi.org/10.1124/mol.118.115048
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    Ti0.8O2 Nanosheets Inhibit Lung Cancer Stem Cells by Inducing Production of Superoxide Anion
    Nalinrat Petpiroon, Narumol Bhummaphan, Rapeepun Soonnarong, Wipa Chantarawong, Tosapol Maluangnont, Varisa Pongrakhananon and Pithi Chanvorachote
    Molecular Pharmacology April 2019, 95 (4) 418-432; DOI: https://doi.org/10.1124/mol.118.114447
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    trans-Anethole of Fennel Oil is a Selective and Nonelectrophilic Agonist of the TRPA1 Ion Channel
    Tosifa Memon, Oleg Yarishkin, Christopher A. Reilly, David Križaj, Baldomero M. Olivera and Russell W. Teichert
    Molecular Pharmacology April 2019, 95 (4) 433-441; DOI: https://doi.org/10.1124/mol.118.114561
  • Open Access
    MiR-144 Inhibits Tumor Growth and Metastasis in Osteosarcoma via Dual-suppressing RhoA/ROCK1 Signaling Pathway
    Jin Long Liu, Jing Li, Jia Jia Xu, Fei Xiao, Peng Lei Cui, Zhi Guang Qiao, Xiao Dong Chen, Wei Dong Tao and Xiao Ling Zhang
    Molecular Pharmacology April 2019, 95 (4) 451-461; DOI: https://doi.org/10.1124/mol.118.114207

Notice of Retraction

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    Re: Dasmahapatra G, Almenara JA, and Grant S, “Flavopiridol and Histone Deacetylase Inhibitors Promote Mitochondrial Injury and Cell Death in Human Leukemia Cells that Overexpress Bcl-2.” Mol Pharmacol January 2006 69:288–298; doi:10.1124/mol.105.016154
    Molecular Pharmacology April 2019, 95 (4) 335; DOI: https://doi.org/10.1124/mol.105.016154retraction
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    Re: Rosato RR, Maggio SC, Almenara JA, Payne SG, Atadja P, Spiegel S, Dent P, and Grant S, “The Histone Deacetylase Inhibitor LAQ824 Induces Human Leukemia Cell Death through a Process Involving XIAP Down-Regulation, Oxidative Injury, and the Acid Sphingomyelinase-Dependent Generation of Ceramide.” Mol Pharmacol January 2006 69:216–225; doi:10.1124/mol.105.017145
    Molecular Pharmacology April 2019, 95 (4) 336; DOI: https://doi.org/10.1124/mol.105.017145retraction

Erratum

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    Correction to “Sodium Ion Binding Pocket Mutations and Adenosine A2A Receptor Function”
    Molecular Pharmacology April 2019, 95 (4) 462; DOI: https://doi.org/10.1124/mol.114.095737err
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Molecular Pharmacology: 95 (4)
Molecular Pharmacology
Vol. 95, Issue 4
1 Apr 2019
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