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Index by author

October 01, 2019; Volume 96,Issue 4

A

  1. Ahmadi, Saumel

    1. ORKAMBI-Mediated Rescue of Mucociliary Clearance in Cystic Fibrosis Primary Respiratory Cultures Is Enhanced by Arginine Uptake, Arginase Inhibition, and Promotion of Nitric Oxide Signaling to the Cystic Fibrosis Transmembrane Conductance Regulator Channel
      Yu-Sheng Wu, Janet Jiang, Saumel Ahmadi, Alexandria Lew, Onofrio Laselva, Sunny Xia, Claire Bartlett, Wan Ip, Leigh Wellhauser, Hong Ouyang, Tanja Gonska, Theo J. Moraes and Christine E. Bear
      Molecular Pharmacology October 2019, 96 (4) 515-525; DOI: https://doi.org/10.1124/mol.119.117143

  2. Armstrong, Lyle

    1. Intercalating TOP2 Poisons Attenuate Topoisomerase Action at Higher Concentrations
      Mandeep Atwal, Rebecca L. Swan, Chloe Rowe, Ka C. Lee, David C. Lee, Lyle Armstrong, Ian G. Cowell and Caroline A. Austin
      Molecular Pharmacology October 2019, 96 (4) 475-484; DOI: https://doi.org/10.1124/mol.119.117259

  3. Arttamangkul, Seksiri

    1. Separation of Acute Desensitization and Long-Term Tolerance of µ-Opioid Receptors Is Determined by the Degree of C-Terminal Phosphorylation
      Seksiri Arttamangkul, Emily R. Leff, Omar Koita, William T. Birdsong and John T. Williams
      Molecular Pharmacology October 2019, 96 (4) 505-514; DOI: https://doi.org/10.1124/mol.119.117358

  4. Atwal, Mandeep

    1. Intercalating TOP2 Poisons Attenuate Topoisomerase Action at Higher Concentrations
      Mandeep Atwal, Rebecca L. Swan, Chloe Rowe, Ka C. Lee, David C. Lee, Lyle Armstrong, Ian G. Cowell and Caroline A. Austin
      Molecular Pharmacology October 2019, 96 (4) 475-484; DOI: https://doi.org/10.1124/mol.119.117259

  5. Austin, Caroline A.

    1. Intercalating TOP2 Poisons Attenuate Topoisomerase Action at Higher Concentrations
      Mandeep Atwal, Rebecca L. Swan, Chloe Rowe, Ka C. Lee, David C. Lee, Lyle Armstrong, Ian G. Cowell and Caroline A. Austin
      Molecular Pharmacology October 2019, 96 (4) 475-484; DOI: https://doi.org/10.1124/mol.119.117259

B

  1. Barger, Carter J.

    1. CDK5 Inhibitor Downregulates Mcl-1 and Sensitizes Pancreatic Cancer Cell Lines to Navitoclax
      Open Access
      CDK5 Inhibitor Downregulates Mcl-1 and Sensitizes Pancreatic Cancer Cell Lines to Navitoclax
      Smit Kour, Sandeep Rana, Jacob I. Contreras, Hannah M. King, Caroline M. Robb, Yogesh A. Sonawane, Mourad Bendjennat, Ayrianne J. Crawford, Carter J. Barger, Smitha Kizhake, Xu Luo, Michael A. Hollingsworth and Amarnath Natarajan
      Molecular Pharmacology October 2019, 96 (4) 419-429; DOI: https://doi.org/10.1124/mol.119.116855

  2. Bartlett, Claire

    1. ORKAMBI-Mediated Rescue of Mucociliary Clearance in Cystic Fibrosis Primary Respiratory Cultures Is Enhanced by Arginine Uptake, Arginase Inhibition, and Promotion of Nitric Oxide Signaling to the Cystic Fibrosis Transmembrane Conductance Regulator Channel
      Yu-Sheng Wu, Janet Jiang, Saumel Ahmadi, Alexandria Lew, Onofrio Laselva, Sunny Xia, Claire Bartlett, Wan Ip, Leigh Wellhauser, Hong Ouyang, Tanja Gonska, Theo J. Moraes and Christine E. Bear
      Molecular Pharmacology October 2019, 96 (4) 515-525; DOI: https://doi.org/10.1124/mol.119.117143

  3. Bear, Christine E.

    1. ORKAMBI-Mediated Rescue of Mucociliary Clearance in Cystic Fibrosis Primary Respiratory Cultures Is Enhanced by Arginine Uptake, Arginase Inhibition, and Promotion of Nitric Oxide Signaling to the Cystic Fibrosis Transmembrane Conductance Regulator Channel
      Yu-Sheng Wu, Janet Jiang, Saumel Ahmadi, Alexandria Lew, Onofrio Laselva, Sunny Xia, Claire Bartlett, Wan Ip, Leigh Wellhauser, Hong Ouyang, Tanja Gonska, Theo J. Moraes and Christine E. Bear
      Molecular Pharmacology October 2019, 96 (4) 515-525; DOI: https://doi.org/10.1124/mol.119.117143

  4. Bendjennat, Mourad

    1. CDK5 Inhibitor Downregulates Mcl-1 and Sensitizes Pancreatic Cancer Cell Lines to Navitoclax
      Open Access
      CDK5 Inhibitor Downregulates Mcl-1 and Sensitizes Pancreatic Cancer Cell Lines to Navitoclax
      Smit Kour, Sandeep Rana, Jacob I. Contreras, Hannah M. King, Caroline M. Robb, Yogesh A. Sonawane, Mourad Bendjennat, Ayrianne J. Crawford, Carter J. Barger, Smitha Kizhake, Xu Luo, Michael A. Hollingsworth and Amarnath Natarajan
      Molecular Pharmacology October 2019, 96 (4) 419-429; DOI: https://doi.org/10.1124/mol.119.116855

  5. Birdsong, William T.

    1. Separation of Acute Desensitization and Long-Term Tolerance of µ-Opioid Receptors Is Determined by the Degree of C-Terminal Phosphorylation
      Seksiri Arttamangkul, Emily R. Leff, Omar Koita, William T. Birdsong and John T. Williams
      Molecular Pharmacology October 2019, 96 (4) 505-514; DOI: https://doi.org/10.1124/mol.119.117358

  6. Bräuner-Osborne, Hans

    1. Open Access
      Calcium-Sensing Receptor Internalization Is β-Arrestin–Dependent and Modulated by Allosteric Ligands
      Iris Mos, Stine E. Jacobsen, Simon R. Foster and Hans Bräuner-Osborne
      Molecular Pharmacology October 2019, 96 (4) 463-474; DOI: https://doi.org/10.1124/mol.119.116772

C

  1. Catterall, William A.

    1. Structural Basis for Diltiazem Block of a Voltage-Gated Ca2+ Channel
      Lin Tang, Tamer M. Gamal El-Din, Michael J. Lenaeus, Ning Zheng and William A. Catterall
      Molecular Pharmacology October 2019, 96 (4) 485-492; DOI: https://doi.org/10.1124/mol.119.117531

  2. Contreras, Jacob I.

    1. CDK5 Inhibitor Downregulates Mcl-1 and Sensitizes Pancreatic Cancer Cell Lines to Navitoclax
      Open Access
      CDK5 Inhibitor Downregulates Mcl-1 and Sensitizes Pancreatic Cancer Cell Lines to Navitoclax
      Smit Kour, Sandeep Rana, Jacob I. Contreras, Hannah M. King, Caroline M. Robb, Yogesh A. Sonawane, Mourad Bendjennat, Ayrianne J. Crawford, Carter J. Barger, Smitha Kizhake, Xu Luo, Michael A. Hollingsworth and Amarnath Natarajan
      Molecular Pharmacology October 2019, 96 (4) 419-429; DOI: https://doi.org/10.1124/mol.119.116855

  3. Cowell, Ian G.

    1. Intercalating TOP2 Poisons Attenuate Topoisomerase Action at Higher Concentrations
      Mandeep Atwal, Rebecca L. Swan, Chloe Rowe, Ka C. Lee, David C. Lee, Lyle Armstrong, Ian G. Cowell and Caroline A. Austin
      Molecular Pharmacology October 2019, 96 (4) 475-484; DOI: https://doi.org/10.1124/mol.119.117259

  4. Crawford, Ayrianne J.

    1. CDK5 Inhibitor Downregulates Mcl-1 and Sensitizes Pancreatic Cancer Cell Lines to Navitoclax
      Open Access
      CDK5 Inhibitor Downregulates Mcl-1 and Sensitizes Pancreatic Cancer Cell Lines to Navitoclax
      Smit Kour, Sandeep Rana, Jacob I. Contreras, Hannah M. King, Caroline M. Robb, Yogesh A. Sonawane, Mourad Bendjennat, Ayrianne J. Crawford, Carter J. Barger, Smitha Kizhake, Xu Luo, Michael A. Hollingsworth and Amarnath Natarajan
      Molecular Pharmacology October 2019, 96 (4) 419-429; DOI: https://doi.org/10.1124/mol.119.116855

  5. Cui, Linran

    1. Activity of Adenylyl Cyclase Type 6 Is Suppressed by Direct Binding of the Cytoskeletal Protein 4.1G
      Masaki Saito, Linran Cui, Marina Hirano, Guanjie Li, Teruyuki Yanagisawa, Takeya Sato and Jun Sukegawa
      Molecular Pharmacology October 2019, 96 (4) 441-451; DOI: https://doi.org/10.1124/mol.119.116426

E

  1. Eshleman, Amy J.

    1. Activation of Trace Amine-Associated Receptor 1 Stimulates an Antiapoptotic Signal Cascade via Extracellular Signal-Regulated Kinase 1/2
      Xiao Shi, Tracy L. Swanson, Nicholas B. Miner, Amy J. Eshleman and Aaron Janowsky
      Molecular Pharmacology October 2019, 96 (4) 493-504; DOI: https://doi.org/10.1124/mol.119.116798

F

  1. Foster, Simon R.

    1. Open Access
      Calcium-Sensing Receptor Internalization Is β-Arrestin–Dependent and Modulated by Allosteric Ligands
      Iris Mos, Stine E. Jacobsen, Simon R. Foster and Hans Bräuner-Osborne
      Molecular Pharmacology October 2019, 96 (4) 463-474; DOI: https://doi.org/10.1124/mol.119.116772

  2. Furkert, Jens

    1. Thyrotropin Receptor: Allosteric Modulators Illuminate Intramolecular Signaling Mechanisms at the Interface of Ecto- and Transmembrane Domain
      Patrick Marcinkowski, Annika Kreuchwig, Sandro Mendieta, Inna Hoyer, Franziska Witte, Jens Furkert, Claudia Rutz, Dieter Lentz, Gerd Krause and Ralf Schülein
      Molecular Pharmacology October 2019, 96 (4) 452-462; DOI: https://doi.org/10.1124/mol.119.116947

G

  1. Gamal El-Din, Tamer M.

    1. Structural Basis for Diltiazem Block of a Voltage-Gated Ca2+ Channel
      Lin Tang, Tamer M. Gamal El-Din, Michael J. Lenaeus, Ning Zheng and William A. Catterall
      Molecular Pharmacology October 2019, 96 (4) 485-492; DOI: https://doi.org/10.1124/mol.119.117531

  2. Gonska, Tanja

    1. ORKAMBI-Mediated Rescue of Mucociliary Clearance in Cystic Fibrosis Primary Respiratory Cultures Is Enhanced by Arginine Uptake, Arginase Inhibition, and Promotion of Nitric Oxide Signaling to the Cystic Fibrosis Transmembrane Conductance Regulator Channel
      Yu-Sheng Wu, Janet Jiang, Saumel Ahmadi, Alexandria Lew, Onofrio Laselva, Sunny Xia, Claire Bartlett, Wan Ip, Leigh Wellhauser, Hong Ouyang, Tanja Gonska, Theo J. Moraes and Christine E. Bear
      Molecular Pharmacology October 2019, 96 (4) 515-525; DOI: https://doi.org/10.1124/mol.119.117143

H

  1. Hirano, Marina

    1. Activity of Adenylyl Cyclase Type 6 Is Suppressed by Direct Binding of the Cytoskeletal Protein 4.1G
      Masaki Saito, Linran Cui, Marina Hirano, Guanjie Li, Teruyuki Yanagisawa, Takeya Sato and Jun Sukegawa
      Molecular Pharmacology October 2019, 96 (4) 441-451; DOI: https://doi.org/10.1124/mol.119.116426

  2. Hollingsworth, Michael A.

    1. CDK5 Inhibitor Downregulates Mcl-1 and Sensitizes Pancreatic Cancer Cell Lines to Navitoclax
      Open Access
      CDK5 Inhibitor Downregulates Mcl-1 and Sensitizes Pancreatic Cancer Cell Lines to Navitoclax
      Smit Kour, Sandeep Rana, Jacob I. Contreras, Hannah M. King, Caroline M. Robb, Yogesh A. Sonawane, Mourad Bendjennat, Ayrianne J. Crawford, Carter J. Barger, Smitha Kizhake, Xu Luo, Michael A. Hollingsworth and Amarnath Natarajan
      Molecular Pharmacology October 2019, 96 (4) 419-429; DOI: https://doi.org/10.1124/mol.119.116855

  3. Hoyer, Inna

    1. Thyrotropin Receptor: Allosteric Modulators Illuminate Intramolecular Signaling Mechanisms at the Interface of Ecto- and Transmembrane Domain
      Patrick Marcinkowski, Annika Kreuchwig, Sandro Mendieta, Inna Hoyer, Franziska Witte, Jens Furkert, Claudia Rutz, Dieter Lentz, Gerd Krause and Ralf Schülein
      Molecular Pharmacology October 2019, 96 (4) 452-462; DOI: https://doi.org/10.1124/mol.119.116947

I

  1. Ip, Wan

    1. ORKAMBI-Mediated Rescue of Mucociliary Clearance in Cystic Fibrosis Primary Respiratory Cultures Is Enhanced by Arginine Uptake, Arginase Inhibition, and Promotion of Nitric Oxide Signaling to the Cystic Fibrosis Transmembrane Conductance Regulator Channel
      Yu-Sheng Wu, Janet Jiang, Saumel Ahmadi, Alexandria Lew, Onofrio Laselva, Sunny Xia, Claire Bartlett, Wan Ip, Leigh Wellhauser, Hong Ouyang, Tanja Gonska, Theo J. Moraes and Christine E. Bear
      Molecular Pharmacology October 2019, 96 (4) 515-525; DOI: https://doi.org/10.1124/mol.119.117143

J

  1. Jacobsen, Stine E.

    1. Open Access
      Calcium-Sensing Receptor Internalization Is β-Arrestin–Dependent and Modulated by Allosteric Ligands
      Iris Mos, Stine E. Jacobsen, Simon R. Foster and Hans Bräuner-Osborne
      Molecular Pharmacology October 2019, 96 (4) 463-474; DOI: https://doi.org/10.1124/mol.119.116772

  2. Janowsky, Aaron

    1. Activation of Trace Amine-Associated Receptor 1 Stimulates an Antiapoptotic Signal Cascade via Extracellular Signal-Regulated Kinase 1/2
      Xiao Shi, Tracy L. Swanson, Nicholas B. Miner, Amy J. Eshleman and Aaron Janowsky
      Molecular Pharmacology October 2019, 96 (4) 493-504; DOI: https://doi.org/10.1124/mol.119.116798

  3. Jiang, Janet

    1. ORKAMBI-Mediated Rescue of Mucociliary Clearance in Cystic Fibrosis Primary Respiratory Cultures Is Enhanced by Arginine Uptake, Arginase Inhibition, and Promotion of Nitric Oxide Signaling to the Cystic Fibrosis Transmembrane Conductance Regulator Channel
      Yu-Sheng Wu, Janet Jiang, Saumel Ahmadi, Alexandria Lew, Onofrio Laselva, Sunny Xia, Claire Bartlett, Wan Ip, Leigh Wellhauser, Hong Ouyang, Tanja Gonska, Theo J. Moraes and Christine E. Bear
      Molecular Pharmacology October 2019, 96 (4) 515-525; DOI: https://doi.org/10.1124/mol.119.117143

K

  1. King, Hannah M.

    1. CDK5 Inhibitor Downregulates Mcl-1 and Sensitizes Pancreatic Cancer Cell Lines to Navitoclax
      Open Access
      CDK5 Inhibitor Downregulates Mcl-1 and Sensitizes Pancreatic Cancer Cell Lines to Navitoclax
      Smit Kour, Sandeep Rana, Jacob I. Contreras, Hannah M. King, Caroline M. Robb, Yogesh A. Sonawane, Mourad Bendjennat, Ayrianne J. Crawford, Carter J. Barger, Smitha Kizhake, Xu Luo, Michael A. Hollingsworth and Amarnath Natarajan
      Molecular Pharmacology October 2019, 96 (4) 419-429; DOI: https://doi.org/10.1124/mol.119.116855

  2. Kizhake, Smitha

    1. CDK5 Inhibitor Downregulates Mcl-1 and Sensitizes Pancreatic Cancer Cell Lines to Navitoclax
      Open Access
      CDK5 Inhibitor Downregulates Mcl-1 and Sensitizes Pancreatic Cancer Cell Lines to Navitoclax
      Smit Kour, Sandeep Rana, Jacob I. Contreras, Hannah M. King, Caroline M. Robb, Yogesh A. Sonawane, Mourad Bendjennat, Ayrianne J. Crawford, Carter J. Barger, Smitha Kizhake, Xu Luo, Michael A. Hollingsworth and Amarnath Natarajan
      Molecular Pharmacology October 2019, 96 (4) 419-429; DOI: https://doi.org/10.1124/mol.119.116855

  3. Koita, Omar

    1. Separation of Acute Desensitization and Long-Term Tolerance of µ-Opioid Receptors Is Determined by the Degree of C-Terminal Phosphorylation
      Seksiri Arttamangkul, Emily R. Leff, Omar Koita, William T. Birdsong and John T. Williams
      Molecular Pharmacology October 2019, 96 (4) 505-514; DOI: https://doi.org/10.1124/mol.119.117358

  4. Kour, Smit

    1. CDK5 Inhibitor Downregulates Mcl-1 and Sensitizes Pancreatic Cancer Cell Lines to Navitoclax
      Open Access
      CDK5 Inhibitor Downregulates Mcl-1 and Sensitizes Pancreatic Cancer Cell Lines to Navitoclax
      Smit Kour, Sandeep Rana, Jacob I. Contreras, Hannah M. King, Caroline M. Robb, Yogesh A. Sonawane, Mourad Bendjennat, Ayrianne J. Crawford, Carter J. Barger, Smitha Kizhake, Xu Luo, Michael A. Hollingsworth and Amarnath Natarajan
      Molecular Pharmacology October 2019, 96 (4) 419-429; DOI: https://doi.org/10.1124/mol.119.116855

  5. Krause, Gerd

    1. Thyrotropin Receptor: Allosteric Modulators Illuminate Intramolecular Signaling Mechanisms at the Interface of Ecto- and Transmembrane Domain
      Patrick Marcinkowski, Annika Kreuchwig, Sandro Mendieta, Inna Hoyer, Franziska Witte, Jens Furkert, Claudia Rutz, Dieter Lentz, Gerd Krause and Ralf Schülein
      Molecular Pharmacology October 2019, 96 (4) 452-462; DOI: https://doi.org/10.1124/mol.119.116947

  6. Kreuchwig, Annika

    1. Thyrotropin Receptor: Allosteric Modulators Illuminate Intramolecular Signaling Mechanisms at the Interface of Ecto- and Transmembrane Domain
      Patrick Marcinkowski, Annika Kreuchwig, Sandro Mendieta, Inna Hoyer, Franziska Witte, Jens Furkert, Claudia Rutz, Dieter Lentz, Gerd Krause and Ralf Schülein
      Molecular Pharmacology October 2019, 96 (4) 452-462; DOI: https://doi.org/10.1124/mol.119.116947

L

  1. Laselva, Onofrio

    1. ORKAMBI-Mediated Rescue of Mucociliary Clearance in Cystic Fibrosis Primary Respiratory Cultures Is Enhanced by Arginine Uptake, Arginase Inhibition, and Promotion of Nitric Oxide Signaling to the Cystic Fibrosis Transmembrane Conductance Regulator Channel
      Yu-Sheng Wu, Janet Jiang, Saumel Ahmadi, Alexandria Lew, Onofrio Laselva, Sunny Xia, Claire Bartlett, Wan Ip, Leigh Wellhauser, Hong Ouyang, Tanja Gonska, Theo J. Moraes and Christine E. Bear
      Molecular Pharmacology October 2019, 96 (4) 515-525; DOI: https://doi.org/10.1124/mol.119.117143

  2. Lee, David C.

    1. Intercalating TOP2 Poisons Attenuate Topoisomerase Action at Higher Concentrations
      Mandeep Atwal, Rebecca L. Swan, Chloe Rowe, Ka C. Lee, David C. Lee, Lyle Armstrong, Ian G. Cowell and Caroline A. Austin
      Molecular Pharmacology October 2019, 96 (4) 475-484; DOI: https://doi.org/10.1124/mol.119.117259

  3. Lee, Ka C.

    1. Intercalating TOP2 Poisons Attenuate Topoisomerase Action at Higher Concentrations
      Mandeep Atwal, Rebecca L. Swan, Chloe Rowe, Ka C. Lee, David C. Lee, Lyle Armstrong, Ian G. Cowell and Caroline A. Austin
      Molecular Pharmacology October 2019, 96 (4) 475-484; DOI: https://doi.org/10.1124/mol.119.117259

  4. Leff, Emily R.

    1. Separation of Acute Desensitization and Long-Term Tolerance of µ-Opioid Receptors Is Determined by the Degree of C-Terminal Phosphorylation
      Seksiri Arttamangkul, Emily R. Leff, Omar Koita, William T. Birdsong and John T. Williams
      Molecular Pharmacology October 2019, 96 (4) 505-514; DOI: https://doi.org/10.1124/mol.119.117358

  5. Lenaeus, Michael J.

    1. Structural Basis for Diltiazem Block of a Voltage-Gated Ca2+ Channel
      Lin Tang, Tamer M. Gamal El-Din, Michael J. Lenaeus, Ning Zheng and William A. Catterall
      Molecular Pharmacology October 2019, 96 (4) 485-492; DOI: https://doi.org/10.1124/mol.119.117531

  6. Lentz, Dieter

    1. Thyrotropin Receptor: Allosteric Modulators Illuminate Intramolecular Signaling Mechanisms at the Interface of Ecto- and Transmembrane Domain
      Patrick Marcinkowski, Annika Kreuchwig, Sandro Mendieta, Inna Hoyer, Franziska Witte, Jens Furkert, Claudia Rutz, Dieter Lentz, Gerd Krause and Ralf Schülein
      Molecular Pharmacology October 2019, 96 (4) 452-462; DOI: https://doi.org/10.1124/mol.119.116947

  7. Lew, Alexandria

    1. ORKAMBI-Mediated Rescue of Mucociliary Clearance in Cystic Fibrosis Primary Respiratory Cultures Is Enhanced by Arginine Uptake, Arginase Inhibition, and Promotion of Nitric Oxide Signaling to the Cystic Fibrosis Transmembrane Conductance Regulator Channel
      Yu-Sheng Wu, Janet Jiang, Saumel Ahmadi, Alexandria Lew, Onofrio Laselva, Sunny Xia, Claire Bartlett, Wan Ip, Leigh Wellhauser, Hong Ouyang, Tanja Gonska, Theo J. Moraes and Christine E. Bear
      Molecular Pharmacology October 2019, 96 (4) 515-525; DOI: https://doi.org/10.1124/mol.119.117143

  8. Li, Guanjie

    1. Activity of Adenylyl Cyclase Type 6 Is Suppressed by Direct Binding of the Cytoskeletal Protein 4.1G
      Masaki Saito, Linran Cui, Marina Hirano, Guanjie Li, Teruyuki Yanagisawa, Takeya Sato and Jun Sukegawa
      Molecular Pharmacology October 2019, 96 (4) 441-451; DOI: https://doi.org/10.1124/mol.119.116426

  9. Liu, Xu

    1. First High-Resolution Crystal Structures of the Glucocorticoid Receptor Ligand-Binding Domain–Peroxisome Proliferator-Activated γ Coactivator 1-α Complex with Endogenous and Synthetic Glucocorticoids
      Xu Liu, Yashuo Wang and Eric A. Ortlund
      Molecular Pharmacology October 2019, 96 (4) 408-417; DOI: https://doi.org/10.1124/mol.119.116806

  10. Lu, Rong

    1. Ligand-Free Estrogen Receptor α (ESR1) as Master Regulator for the Expression of CYP3A4 and Other Cytochrome P450 Enzymes in the Human Liver
      Danxin Wang, Rong Lu, Grzegorz Rempala and Wolfgang Sadee
      Molecular Pharmacology October 2019, 96 (4) 430-440; DOI: https://doi.org/10.1124/mol.119.116897

  11. Luo, Xu

    1. CDK5 Inhibitor Downregulates Mcl-1 and Sensitizes Pancreatic Cancer Cell Lines to Navitoclax
      Open Access
      CDK5 Inhibitor Downregulates Mcl-1 and Sensitizes Pancreatic Cancer Cell Lines to Navitoclax
      Smit Kour, Sandeep Rana, Jacob I. Contreras, Hannah M. King, Caroline M. Robb, Yogesh A. Sonawane, Mourad Bendjennat, Ayrianne J. Crawford, Carter J. Barger, Smitha Kizhake, Xu Luo, Michael A. Hollingsworth and Amarnath Natarajan
      Molecular Pharmacology October 2019, 96 (4) 419-429; DOI: https://doi.org/10.1124/mol.119.116855

M

  1. Marcinkowski, Patrick

    1. Thyrotropin Receptor: Allosteric Modulators Illuminate Intramolecular Signaling Mechanisms at the Interface of Ecto- and Transmembrane Domain
      Patrick Marcinkowski, Annika Kreuchwig, Sandro Mendieta, Inna Hoyer, Franziska Witte, Jens Furkert, Claudia Rutz, Dieter Lentz, Gerd Krause and Ralf Schülein
      Molecular Pharmacology October 2019, 96 (4) 452-462; DOI: https://doi.org/10.1124/mol.119.116947

  2. Mendieta, Sandro

    1. Thyrotropin Receptor: Allosteric Modulators Illuminate Intramolecular Signaling Mechanisms at the Interface of Ecto- and Transmembrane Domain
      Patrick Marcinkowski, Annika Kreuchwig, Sandro Mendieta, Inna Hoyer, Franziska Witte, Jens Furkert, Claudia Rutz, Dieter Lentz, Gerd Krause and Ralf Schülein
      Molecular Pharmacology October 2019, 96 (4) 452-462; DOI: https://doi.org/10.1124/mol.119.116947

  3. Miner, Nicholas B.

    1. Activation of Trace Amine-Associated Receptor 1 Stimulates an Antiapoptotic Signal Cascade via Extracellular Signal-Regulated Kinase 1/2
      Xiao Shi, Tracy L. Swanson, Nicholas B. Miner, Amy J. Eshleman and Aaron Janowsky
      Molecular Pharmacology October 2019, 96 (4) 493-504; DOI: https://doi.org/10.1124/mol.119.116798

  4. Moraes, Theo J.

    1. ORKAMBI-Mediated Rescue of Mucociliary Clearance in Cystic Fibrosis Primary Respiratory Cultures Is Enhanced by Arginine Uptake, Arginase Inhibition, and Promotion of Nitric Oxide Signaling to the Cystic Fibrosis Transmembrane Conductance Regulator Channel
      Yu-Sheng Wu, Janet Jiang, Saumel Ahmadi, Alexandria Lew, Onofrio Laselva, Sunny Xia, Claire Bartlett, Wan Ip, Leigh Wellhauser, Hong Ouyang, Tanja Gonska, Theo J. Moraes and Christine E. Bear
      Molecular Pharmacology October 2019, 96 (4) 515-525; DOI: https://doi.org/10.1124/mol.119.117143

  5. Mos, Iris

    1. Open Access
      Calcium-Sensing Receptor Internalization Is β-Arrestin–Dependent and Modulated by Allosteric Ligands
      Iris Mos, Stine E. Jacobsen, Simon R. Foster and Hans Bräuner-Osborne
      Molecular Pharmacology October 2019, 96 (4) 463-474; DOI: https://doi.org/10.1124/mol.119.116772

N

  1. Natarajan, Amarnath

    1. CDK5 Inhibitor Downregulates Mcl-1 and Sensitizes Pancreatic Cancer Cell Lines to Navitoclax
      Open Access
      CDK5 Inhibitor Downregulates Mcl-1 and Sensitizes Pancreatic Cancer Cell Lines to Navitoclax
      Smit Kour, Sandeep Rana, Jacob I. Contreras, Hannah M. King, Caroline M. Robb, Yogesh A. Sonawane, Mourad Bendjennat, Ayrianne J. Crawford, Carter J. Barger, Smitha Kizhake, Xu Luo, Michael A. Hollingsworth and Amarnath Natarajan
      Molecular Pharmacology October 2019, 96 (4) 419-429; DOI: https://doi.org/10.1124/mol.119.116855

O

  1. Ortlund, Eric A.

    1. First High-Resolution Crystal Structures of the Glucocorticoid Receptor Ligand-Binding Domain–Peroxisome Proliferator-Activated γ Coactivator 1-α Complex with Endogenous and Synthetic Glucocorticoids
      Xu Liu, Yashuo Wang and Eric A. Ortlund
      Molecular Pharmacology October 2019, 96 (4) 408-417; DOI: https://doi.org/10.1124/mol.119.116806

  2. Ouyang, Hong

    1. ORKAMBI-Mediated Rescue of Mucociliary Clearance in Cystic Fibrosis Primary Respiratory Cultures Is Enhanced by Arginine Uptake, Arginase Inhibition, and Promotion of Nitric Oxide Signaling to the Cystic Fibrosis Transmembrane Conductance Regulator Channel
      Yu-Sheng Wu, Janet Jiang, Saumel Ahmadi, Alexandria Lew, Onofrio Laselva, Sunny Xia, Claire Bartlett, Wan Ip, Leigh Wellhauser, Hong Ouyang, Tanja Gonska, Theo J. Moraes and Christine E. Bear
      Molecular Pharmacology October 2019, 96 (4) 515-525; DOI: https://doi.org/10.1124/mol.119.117143

R

  1. Rana, Sandeep

    1. CDK5 Inhibitor Downregulates Mcl-1 and Sensitizes Pancreatic Cancer Cell Lines to Navitoclax
      Open Access
      CDK5 Inhibitor Downregulates Mcl-1 and Sensitizes Pancreatic Cancer Cell Lines to Navitoclax
      Smit Kour, Sandeep Rana, Jacob I. Contreras, Hannah M. King, Caroline M. Robb, Yogesh A. Sonawane, Mourad Bendjennat, Ayrianne J. Crawford, Carter J. Barger, Smitha Kizhake, Xu Luo, Michael A. Hollingsworth and Amarnath Natarajan
      Molecular Pharmacology October 2019, 96 (4) 419-429; DOI: https://doi.org/10.1124/mol.119.116855

  2. Rempala, Grzegorz

    1. Ligand-Free Estrogen Receptor α (ESR1) as Master Regulator for the Expression of CYP3A4 and Other Cytochrome P450 Enzymes in the Human Liver
      Danxin Wang, Rong Lu, Grzegorz Rempala and Wolfgang Sadee
      Molecular Pharmacology October 2019, 96 (4) 430-440; DOI: https://doi.org/10.1124/mol.119.116897

  3. Robb, Caroline M.

    1. CDK5 Inhibitor Downregulates Mcl-1 and Sensitizes Pancreatic Cancer Cell Lines to Navitoclax
      Open Access
      CDK5 Inhibitor Downregulates Mcl-1 and Sensitizes Pancreatic Cancer Cell Lines to Navitoclax
      Smit Kour, Sandeep Rana, Jacob I. Contreras, Hannah M. King, Caroline M. Robb, Yogesh A. Sonawane, Mourad Bendjennat, Ayrianne J. Crawford, Carter J. Barger, Smitha Kizhake, Xu Luo, Michael A. Hollingsworth and Amarnath Natarajan
      Molecular Pharmacology October 2019, 96 (4) 419-429; DOI: https://doi.org/10.1124/mol.119.116855

  4. Rowe, Chloe

    1. Intercalating TOP2 Poisons Attenuate Topoisomerase Action at Higher Concentrations
      Mandeep Atwal, Rebecca L. Swan, Chloe Rowe, Ka C. Lee, David C. Lee, Lyle Armstrong, Ian G. Cowell and Caroline A. Austin
      Molecular Pharmacology October 2019, 96 (4) 475-484; DOI: https://doi.org/10.1124/mol.119.117259

  5. Rutz, Claudia

    1. Thyrotropin Receptor: Allosteric Modulators Illuminate Intramolecular Signaling Mechanisms at the Interface of Ecto- and Transmembrane Domain
      Patrick Marcinkowski, Annika Kreuchwig, Sandro Mendieta, Inna Hoyer, Franziska Witte, Jens Furkert, Claudia Rutz, Dieter Lentz, Gerd Krause and Ralf Schülein
      Molecular Pharmacology October 2019, 96 (4) 452-462; DOI: https://doi.org/10.1124/mol.119.116947

S

  1. Sadee, Wolfgang

    1. Ligand-Free Estrogen Receptor α (ESR1) as Master Regulator for the Expression of CYP3A4 and Other Cytochrome P450 Enzymes in the Human Liver
      Danxin Wang, Rong Lu, Grzegorz Rempala and Wolfgang Sadee
      Molecular Pharmacology October 2019, 96 (4) 430-440; DOI: https://doi.org/10.1124/mol.119.116897

  2. Saito, Masaki

    1. Activity of Adenylyl Cyclase Type 6 Is Suppressed by Direct Binding of the Cytoskeletal Protein 4.1G
      Masaki Saito, Linran Cui, Marina Hirano, Guanjie Li, Teruyuki Yanagisawa, Takeya Sato and Jun Sukegawa
      Molecular Pharmacology October 2019, 96 (4) 441-451; DOI: https://doi.org/10.1124/mol.119.116426

  3. Sato, Takeya

    1. Activity of Adenylyl Cyclase Type 6 Is Suppressed by Direct Binding of the Cytoskeletal Protein 4.1G
      Masaki Saito, Linran Cui, Marina Hirano, Guanjie Li, Teruyuki Yanagisawa, Takeya Sato and Jun Sukegawa
      Molecular Pharmacology October 2019, 96 (4) 441-451; DOI: https://doi.org/10.1124/mol.119.116426

  4. Schülein, Ralf

    1. Thyrotropin Receptor: Allosteric Modulators Illuminate Intramolecular Signaling Mechanisms at the Interface of Ecto- and Transmembrane Domain
      Patrick Marcinkowski, Annika Kreuchwig, Sandro Mendieta, Inna Hoyer, Franziska Witte, Jens Furkert, Claudia Rutz, Dieter Lentz, Gerd Krause and Ralf Schülein
      Molecular Pharmacology October 2019, 96 (4) 452-462; DOI: https://doi.org/10.1124/mol.119.116947

  5. Shi, Xiao

    1. Activation of Trace Amine-Associated Receptor 1 Stimulates an Antiapoptotic Signal Cascade via Extracellular Signal-Regulated Kinase 1/2
      Xiao Shi, Tracy L. Swanson, Nicholas B. Miner, Amy J. Eshleman and Aaron Janowsky
      Molecular Pharmacology October 2019, 96 (4) 493-504; DOI: https://doi.org/10.1124/mol.119.116798

  6. Sonawane, Yogesh A.

    1. CDK5 Inhibitor Downregulates Mcl-1 and Sensitizes Pancreatic Cancer Cell Lines to Navitoclax
      Open Access
      CDK5 Inhibitor Downregulates Mcl-1 and Sensitizes Pancreatic Cancer Cell Lines to Navitoclax
      Smit Kour, Sandeep Rana, Jacob I. Contreras, Hannah M. King, Caroline M. Robb, Yogesh A. Sonawane, Mourad Bendjennat, Ayrianne J. Crawford, Carter J. Barger, Smitha Kizhake, Xu Luo, Michael A. Hollingsworth and Amarnath Natarajan
      Molecular Pharmacology October 2019, 96 (4) 419-429; DOI: https://doi.org/10.1124/mol.119.116855

  7. Sukegawa, Jun

    1. Activity of Adenylyl Cyclase Type 6 Is Suppressed by Direct Binding of the Cytoskeletal Protein 4.1G
      Masaki Saito, Linran Cui, Marina Hirano, Guanjie Li, Teruyuki Yanagisawa, Takeya Sato and Jun Sukegawa
      Molecular Pharmacology October 2019, 96 (4) 441-451; DOI: https://doi.org/10.1124/mol.119.116426

  8. Swan, Rebecca L.

    1. Intercalating TOP2 Poisons Attenuate Topoisomerase Action at Higher Concentrations
      Mandeep Atwal, Rebecca L. Swan, Chloe Rowe, Ka C. Lee, David C. Lee, Lyle Armstrong, Ian G. Cowell and Caroline A. Austin
      Molecular Pharmacology October 2019, 96 (4) 475-484; DOI: https://doi.org/10.1124/mol.119.117259

  9. Swanson, Tracy L.

    1. Activation of Trace Amine-Associated Receptor 1 Stimulates an Antiapoptotic Signal Cascade via Extracellular Signal-Regulated Kinase 1/2
      Xiao Shi, Tracy L. Swanson, Nicholas B. Miner, Amy J. Eshleman and Aaron Janowsky
      Molecular Pharmacology October 2019, 96 (4) 493-504; DOI: https://doi.org/10.1124/mol.119.116798

T

  1. Tang, Lin

    1. Structural Basis for Diltiazem Block of a Voltage-Gated Ca2+ Channel
      Lin Tang, Tamer M. Gamal El-Din, Michael J. Lenaeus, Ning Zheng and William A. Catterall
      Molecular Pharmacology October 2019, 96 (4) 485-492; DOI: https://doi.org/10.1124/mol.119.117531

W

  1. Wang, Danxin

    1. Ligand-Free Estrogen Receptor α (ESR1) as Master Regulator for the Expression of CYP3A4 and Other Cytochrome P450 Enzymes in the Human Liver
      Danxin Wang, Rong Lu, Grzegorz Rempala and Wolfgang Sadee
      Molecular Pharmacology October 2019, 96 (4) 430-440; DOI: https://doi.org/10.1124/mol.119.116897

  2. Wang, Yashuo

    1. First High-Resolution Crystal Structures of the Glucocorticoid Receptor Ligand-Binding Domain–Peroxisome Proliferator-Activated γ Coactivator 1-α Complex with Endogenous and Synthetic Glucocorticoids
      Xu Liu, Yashuo Wang and Eric A. Ortlund
      Molecular Pharmacology October 2019, 96 (4) 408-417; DOI: https://doi.org/10.1124/mol.119.116806

  3. Wellhauser, Leigh

    1. ORKAMBI-Mediated Rescue of Mucociliary Clearance in Cystic Fibrosis Primary Respiratory Cultures Is Enhanced by Arginine Uptake, Arginase Inhibition, and Promotion of Nitric Oxide Signaling to the Cystic Fibrosis Transmembrane Conductance Regulator Channel
      Yu-Sheng Wu, Janet Jiang, Saumel Ahmadi, Alexandria Lew, Onofrio Laselva, Sunny Xia, Claire Bartlett, Wan Ip, Leigh Wellhauser, Hong Ouyang, Tanja Gonska, Theo J. Moraes and Christine E. Bear
      Molecular Pharmacology October 2019, 96 (4) 515-525; DOI: https://doi.org/10.1124/mol.119.117143

  4. Williams, John T.

    1. Separation of Acute Desensitization and Long-Term Tolerance of µ-Opioid Receptors Is Determined by the Degree of C-Terminal Phosphorylation
      Seksiri Arttamangkul, Emily R. Leff, Omar Koita, William T. Birdsong and John T. Williams
      Molecular Pharmacology October 2019, 96 (4) 505-514; DOI: https://doi.org/10.1124/mol.119.117358

  5. Witte, Franziska

    1. Thyrotropin Receptor: Allosteric Modulators Illuminate Intramolecular Signaling Mechanisms at the Interface of Ecto- and Transmembrane Domain
      Patrick Marcinkowski, Annika Kreuchwig, Sandro Mendieta, Inna Hoyer, Franziska Witte, Jens Furkert, Claudia Rutz, Dieter Lentz, Gerd Krause and Ralf Schülein
      Molecular Pharmacology October 2019, 96 (4) 452-462; DOI: https://doi.org/10.1124/mol.119.116947

  6. Wu, Yu-Sheng

    1. ORKAMBI-Mediated Rescue of Mucociliary Clearance in Cystic Fibrosis Primary Respiratory Cultures Is Enhanced by Arginine Uptake, Arginase Inhibition, and Promotion of Nitric Oxide Signaling to the Cystic Fibrosis Transmembrane Conductance Regulator Channel
      Yu-Sheng Wu, Janet Jiang, Saumel Ahmadi, Alexandria Lew, Onofrio Laselva, Sunny Xia, Claire Bartlett, Wan Ip, Leigh Wellhauser, Hong Ouyang, Tanja Gonska, Theo J. Moraes and Christine E. Bear
      Molecular Pharmacology October 2019, 96 (4) 515-525; DOI: https://doi.org/10.1124/mol.119.117143

X

  1. Xia, Sunny

    1. ORKAMBI-Mediated Rescue of Mucociliary Clearance in Cystic Fibrosis Primary Respiratory Cultures Is Enhanced by Arginine Uptake, Arginase Inhibition, and Promotion of Nitric Oxide Signaling to the Cystic Fibrosis Transmembrane Conductance Regulator Channel
      Yu-Sheng Wu, Janet Jiang, Saumel Ahmadi, Alexandria Lew, Onofrio Laselva, Sunny Xia, Claire Bartlett, Wan Ip, Leigh Wellhauser, Hong Ouyang, Tanja Gonska, Theo J. Moraes and Christine E. Bear
      Molecular Pharmacology October 2019, 96 (4) 515-525; DOI: https://doi.org/10.1124/mol.119.117143

Y

  1. Yanagisawa, Teruyuki

    1. Activity of Adenylyl Cyclase Type 6 Is Suppressed by Direct Binding of the Cytoskeletal Protein 4.1G
      Masaki Saito, Linran Cui, Marina Hirano, Guanjie Li, Teruyuki Yanagisawa, Takeya Sato and Jun Sukegawa
      Molecular Pharmacology October 2019, 96 (4) 441-451; DOI: https://doi.org/10.1124/mol.119.116426

Z

  1. Zheng, Ning

    1. Structural Basis for Diltiazem Block of a Voltage-Gated Ca2+ Channel
      Lin Tang, Tamer M. Gamal El-Din, Michael J. Lenaeus, Ning Zheng and William A. Catterall
      Molecular Pharmacology October 2019, 96 (4) 485-492; DOI: https://doi.org/10.1124/mol.119.117531
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