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Thyrotropin Receptor: Allosteric Modulators Illuminate Intramolecular Signaling Mechanisms at the Interface of Ecto- and Transmembrane Domain

Patrick Marcinkowski, Annika Kreuchwig, Sandro Mendieta, Inna Hoyer, Franziska Witte, Jens Furkert, Claudia Rutz, Dieter Lentz, Gerd Krause and Ralf Schülein
Molecular Pharmacology October 2019, 96 (4) 452-462; DOI: https://doi.org/10.1124/mol.119.116947

Article Information

vol. 96 no. 4 452-462
DOI 
https://doi.org/10.1124/mol.119.116947
PubMed 
31399504
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received April 29, 2019
  • Accepted July 23, 2019
  • Published online September 10, 2019.

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Copyright & Usage 
Copyright © 2019 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Patrick Marcinkowski,
  2. Annika Kreuchwig,
  3. Sandro Mendieta,
  4. Inna Hoyer,
  5. Franziska Witte1,
  6. Jens Furkert,
  7. Claudia Rutz,
  8. Dieter Lentz,
  9. Gerd Krause, and
  10. Ralf Schülein
  1. Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany (P.M., A.K., S.M., I.H., F.W., J.F., C.R., G.K., R.S.) and Institut für Chemie und Biochemie - Anorganische Chemie, Freie Universität Berlin, Berlin, Germany (D.L.)
  1. Address correspondence to:
    Dr. Gerd Krause, Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Robert-Rössle-Str. 10, 13125 Berlin, Germany. E-mail: GKrause{at}fmp-berlin.de
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TSHR Intramolecular Mechanisms Illuminated by PAM and NAM

Patrick Marcinkowski, Annika Kreuchwig, Sandro Mendieta, Inna Hoyer, Franziska Witte, Jens Furkert, Claudia Rutz, Dieter Lentz, Gerd Krause and Ralf Schülein
Molecular Pharmacology October 1, 2019, 96 (4) 452-462; DOI: https://doi.org/10.1124/mol.119.116947
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