Research ArticleArticle
Open Access
The Deubiquitinating Enzyme Inhibitor PR-619 is a Potent DNA Topoisomerase II Poison
Ian G. Cowell, Elise M. Ling, Rebecca L. Swan, Matilda L.W. Brooks and Caroline A. Austin
Molecular Pharmacology November 2019, 96 (5) 562-572; DOI: https://doi.org/10.1124/mol.119.117390
Ian G. Cowell
Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle upon Tyne, United Kingdom
Elise M. Ling
Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle upon Tyne, United Kingdom
Rebecca L. Swan
Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle upon Tyne, United Kingdom
Matilda L.W. Brooks
Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle upon Tyne, United Kingdom
Caroline A. Austin
Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle upon Tyne, United Kingdom
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PR-619 is a TOP2 Poison
Ian G. Cowell, Elise M. Ling, Rebecca L. Swan, Matilda L.W. Brooks and Caroline A. Austin
Molecular Pharmacology November 1, 2019, 96 (5) 562-572; DOI: https://doi.org/10.1124/mol.119.117390
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