Article Figures & Data
Figures
Tables
Data Supplement
- Supplemental Data -
Supplementary Figure 1 - Crystal packing.
Supplementary Figure 2 - Mg2+ ions omit map.
Supplementary Figure 3 - Thermal shift assay.
Supplementary Figure 4 - Comparison of the bisphosphonates binding sites in the deposited and re-refined yGGPPS structures.
Supplementary Table 1 - Re-refinement of yGGPPS structures.
- Supplemental Data -
Supplementary Data 1 – Crystal structure of hGGPPS in complex with ibandronate (PDB 6R4V).
- Supplemental Data -
Supplementary Data 2 – Re-refined structure of yGGPPS in complex with zoledronate (PDB 2E91).
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Supplementary Data 3 – Re-refined structure of yGGPPS in complex with BPH-252 (PDB 2Z4X).
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Supplementary Data 4 – Re-refined structure of yGGPPS in complex with BPH-23 (PDB 2Z52).
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Supplementary Data 5 – Re-refined structure of yGGPPS in complex with BPH-806 (PDB 2Z78).
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Supplementary Data 6 – Re-refined structure of yGGPPS in complex with BPH-sc01 (PDB 2Z4Z).
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Supplementary Data 7 – Re-refined structure of yGGPPS in complex with minodronate (PDB 2E92).
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Supplementary Data 8 – Re-refined structure of yGGPPS in complex with BPH-675 (PDB 2E95).
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Supplementary Data 9 – Re-refined structure of yGGPPS in complex with BPH-210 (PDB 2Z7H).
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