Table of Contents

Articles

• You have access

  Thyrotropin Causes Dose-dependent Biphasic Regulation of cAMP Production Mediated by G_s and G_i/o Proteins

  Susanne Neumann, Sarah S. Malik, Bernice Marcus-Samuels, Elena Eliseeva, Daesong Jang, Joanna Klubo-Gwiezdzinska, Christine C. Krieger and Marvin C. Gershengorn

  Molecular Pharmacology January 2020, 97 (1) 2-8; DOI: https://doi.org/10.1124/mol.119.117382
• 

  You have access

  Cellular Pharmacodynamics of a Novel Pyrrolo[3,2-d]pyrimidine Inhibitor Targeting Mitochondrial and Cytosolic One-Carbon Metabolism

  Aamod S. Dekhne, Changwen Ning, Md. Junayed Nayeen, Khushbu Shah, Hasini Kalpage, Josephine Frühauf, Adrianne Wallace-Povirk, Carrie O’Connor, Zhanjun Hou, Seongho Kim, Maik Hüttemann, Aleem Gangjee and Larry H. Matherly

  Molecular Pharmacology January 2020, 97 (1) 9-22; DOI: https://doi.org/10.1124/mol.119.117937
• You have access

  A NanoBRET-Based Binding Assay for Smoothened Allows Real-time Analysis of Ligand Binding and Distinction of Two Binding Sites for BODIPY-cyclopamine

  Paweł Kozielewicz, Carl-Fredrik Bowin, Ainoleena Turku and Gunnar Schulte

  Molecular Pharmacology January 2020, 97 (1) 23-34; DOI: https://doi.org/10.1124/mol.119.118158
• You have access

  Evaluation of Operational Models of Agonism and Allosterism at Receptors with Multiple Orthosteric Binding Sites

  Karen J. Gregory, Jesús Giraldo, Jiayin Diao, Arthur Christopoulos and Katie Leach

  Molecular Pharmacology January 2020, 97 (1) 35-47; DOI: https://doi.org/10.1124/mol.119.118091