At the request of Dr. Nina Isoherranen and with the concurrence of all the coauthors except the first author, Molecular Pharmacology has retracted this article. It was found that the first author intentionally fabricated and/or falsified data and analyses represented by Figs. 2A, 3D, 4A, 4F, 5B, 5E, 6B, 6C, and Supplemental Fig. 2a, and in the western blot image found in Supplemental Fig. 2B.
- Copyright © 2020 by The American Society for Pharmacology and Experimental Therapeutics
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- Notice of Retraction: Acharya P, Chen J-J, Correia MA (2010) Hepatic heme-regulated inhibitor (HRI) eukaryotic initiation factor 2α kinase: a protagonist of heme-mediated translational control of CYP2B enzymes and a modulator of basal endoplasmic reticulum stress tone. Mol Pharmacol 77(4):575–592; doi:10.1124/mol.109.061259.
- Notice of Retraction: Acharya P, Engel JC, Correia MA (2009) Hepatic CYP3A suppression by high concentrations of proteasomal inhibitors: A consequence of endoplasmic reticulum (ER) stress induction, activation of RNA-dependent protein kinase-like ER-bound eukaryotic initiation factor 2α (eIF2α)-kinase (PERK) and general control nonderepressible-2 eIF2α kinase (GCN2), and global translational shutoff. Mol Pharmacol 76(3):503–515; DOI: https://doi.org/10.1124/mol.109.056002.
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