Table of Contents

Articles

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  Structural Determinants of Kv7.5 Potassium Channels That Confer Changes in Phosphatidylinositol 4,5-Bisphosphate (PIP₂) Affinity and Signaling Sensitivities in Smooth Muscle Cells

  Lyubov I. Brueggemann, Leanne L. Cribbs and Kenneth L. Byron

  Molecular Pharmacology March 2020, 97 (3) 145-158; DOI: https://doi.org/10.1124/mol.119.117192
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  hsa-miR-9-3p and hsa-miR-9-5p as Post-Transcriptional Modulators of DNA Topoisomerase IIα in Human Leukemia K562 Cells with Acquired Resistance to Etoposide

  Evan E. Kania, Jessika Carvajal-Moreno, Victor A. Hernandez, Anthony English, Jonathan L. Papa, Nicholas Shkolnikov, Hatice Gulcin Ozer, Ayse Selen Yilmaz, Jack C. Yalowich and Terry S. Elton

  Molecular Pharmacology March 2020, 97 (3) 159-170; DOI: https://doi.org/10.1124/mol.119.118315
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  Bupropion Inhibits Serotonin Type 3AB Heteromeric Channels at Clinically Relevant Concentrations

  Antonia G. Stuebler and Michaela Jansen

  Molecular Pharmacology March 2020, 97 (3) 171-179; DOI: https://doi.org/10.1124/mol.119.118349
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  CITCO Directly Binds to and Activates Human Pregnane X Receptor

  Wenwei Lin, Monicah Bwayi, Jing Wu, Yongtao Li, Sergio C. Chai, Andrew D. Huber and Taosheng Chen

  Molecular Pharmacology March 2020, 97 (3) 180-190; DOI: https://doi.org/10.1124/mol.119.118513
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  Ser100-Phosphorylated RORα Orchestrates CAR and HNF4α to Form Active Chromatin Complex in Response to Phenobarbital to Regulate Induction of CYP2B6

  Muluneh Fashe, Takuyu Hashiguchi, Masahiko Negishi and Tatsuya Sueyoshi

  Molecular Pharmacology March 2020, 97 (3) 191-201; DOI: https://doi.org/10.1124/mol.119.118273
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  Interactions between Atorvastatin and the Farnesoid X Receptor Impair Insulinotropic Effects of Bile Acids and Modulate Diabetogenic Risk

  Theresa Hoffmeister, Julia Kaiser, Simon Lüdtke, Gisela Drews and Martina Düfer

  Molecular Pharmacology March 2020, 97 (3) 202-211; DOI: https://doi.org/10.1124/mol.119.118083
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  The Peroxisome Proliferator–Activated Receptor (PPAR)-γ Antagonist 2-Chloro-5-Nitro-N-Phenylbenzamide (GW9662) Triggers Perilipin 2 Expression via PPARδ and Induces Lipogenesis and Triglyceride Accumulation in Human THP-1 Macrophages

  Martin Schubert, Stefanie Becher, Maria Wallert, Marten B. Maeß, Masoumeh Abhari, Knut Rennert, Alexander S. Mosig, Silke Große, Regine Heller, Michael Grün and Stefan Lorkowski

  Molecular Pharmacology March 2020, 97 (3) 212-225; DOI: https://doi.org/10.1124/mol.119.117887
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  Discovery of Small Molecules That Target the Phosphatidylinositol (3,4,5) Trisphosphate (PIP₃)-Dependent Rac Exchanger 1 (P-Rex1) PIP₃-Binding Site and Inhibit P-Rex1–Dependent Functions in Neutrophils

  Jennifer N. Cash, Naincy R. Chandan, Alan Y. Hsu, Prateek V. Sharma, Qing Deng, Alan V. Smrcka and John J.G. Tesmer

  Molecular Pharmacology March 2020, 97 (3) 226-236; DOI: https://doi.org/10.1124/mol.119.117556