Article Figures & Data
Figures
Additional Files
Data Supplement
- Supplemental Figures -
Supplementary Figure 1 - Levels of TOP2-DNA complexes are increased in the presence of UAE inhibitor, PYR-41.
Supplementary Figure 2 - The Nedd8 activating enzyme (NAE) does not contribute significantly to the removal of TOP2-DNA complexes.
Supplementary Figure 3 - MLN7243 does not inhibit SUMOylation of TOP2-DNA complexes.
Supplementary Figure 4 - siRNA knockdown of the ubiquitin activating enzyme UBA6 or UAE and UBA6.
Supplementary Figure 5 - Tightly associated chromatin proteins (histones, RNAPII and Ku80) are removed from TARDIS slides during lysis.
Supplementary Figure 6 - Using the TARDIS assay to investigate the ubiquitination of TOP2-DNA complexes.
- Supplemental Figures -