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Index by author

October 01, 2020; Volume 98,Issue 4

A

  1. Abboud, Khalil A.

    1. Differing Activity Profiles of the Stereoisomers of 2,3,5,6TMP-TQS, a Putative Silent Allosteric Modulator of α7 nAChR
      Roger L. Papke, Sumanta Garai, Clare Stokes, Nicole A. Horenstein, Arthur D. Zimmerman, Khalil A. Abboud and Ganesh A. Thakur
      Molecular Pharmacology October 2020, 98 (4) 292-302; DOI: https://doi.org/10.1124/mol.120.119958

  2. Abd-Elrahman, Khaled S.

    1. Targeting Vesicular Glutamate Transporter Machinery: Implications on Metabotropic Glutamate Receptor 5 Signaling and Behavior
      Karim S. Ibrahim, Khaled S. Abd-Elrahman, Salah El Mestikawy and Stephen S.G. Ferguson
      Molecular Pharmacology October 2020, 98 (4) 315-328; DOI: https://doi.org/10.1124/mol.120.000089
    2. Targeting Vesicular Glutamate Transporter Machinery: Implications on Metabotropic Glutamate Receptor 5 Signaling and Behavior
      Karim S. Ibrahim, Khaled S. Abd-Elrahman, Salah El Mestikawy and Stephen S.G. Ferguson
      Molecular Pharmacology October 2020, 98 (4) 314-327; DOI: https://doi.org/10.1124/molpharm.120.000089

  3. Abderrahman, Balkees

    1. Open Access
      Pharmacology and Molecular Mechanisms of Clinically Relevant Estrogen Estetrol and Estrogen Mimic BMI-135 for the Treatment of Endocrine-Resistant Breast Cancer
      Balkees Abderrahman, Philipp Y. Maximov, Ramona F. Curpan, Jay S. Hanspal, Ping Fan, Rui Xiong, Debra A. Tonetti, Gregory R.J. Thatcher and V. Craig Jordan
      Molecular Pharmacology October 2020, 98 (4) 363-380; DOI: https://doi.org/10.1124/molpharm.120.000054
    2. Open Access
      Pharmacology and Molecular Mechanisms of Clinically Relevant Estrogen Estetrol and Estrogen Mimic BMI-135 for the Treatment of Endocrine-Resistant Breast Cancer
      Balkees Abderrahman, Philipp Y. Maximov, Ramona F. Curpan, Jay S. Hanspal, Ping Fan, Rui Xiong, Debra A. Tonetti, Gregory R.J. Thatcher and V. Craig Jordan
      Molecular Pharmacology October 2020, 98 (4) 364-381; DOI: https://doi.org/10.1124/molpharm.120.000054

  4. Akk, Gustav

    1. Analysis of Modulation of the ρ1 GABAA Receptor by Combinations of Inhibitory and Potentiating Neurosteroids Reveals Shared and Distinct Binding Sites
      Allison L. Germann, David E. Reichert, Ariel B. Burbridge, Spencer R. Pierce, Alex S. Evers, Joe Henry Steinbach and Gustav Akk
      Molecular Pharmacology October 2020, 98 (4) 280-291; DOI: https://doi.org/10.1124/mol.120.119842
    2. Enhancement of Muscimol Binding and Gating by Allosteric Modulators of the GABAA Receptor: Relating Occupancy to State Functions
      Gustav Akk, Allison L. Germann, Yusuke Sugasawa, Spencer R. Pierce, Alex S. Evers and Joe Henry Steinbach
      Molecular Pharmacology October 2020, 98 (4) 303-313; DOI: https://doi.org/10.1124/molpharm.120.000066

  5. Al-Hasani, Ream

    1. Pain, Motivation, Migraine, and the Microbiome: New Frontiers for Opioid Systems and Disease
      Kyle E. Parker, Elizabeth Sugiarto, Anna M.W. Taylor, Amynah A. Pradhan and Ream Al-Hasani
      Molecular Pharmacology October 2020, 98 (4) 433-444; DOI: https://doi.org/10.1124/mol.120.119438

  6. Aleman, Monica

    1. Dietary Caffeine Synergizes Adverse Peripheral and Central Responses to Anesthesia in Malignant Hyperthermia Susceptible Mice
      Monica Aleman, Rui Zhang, Wei Feng, Lihong Qi, Jose R. Lopez, Chelsea Crowe, Yao Dong, Genady Cherednichenko and Isaac N. Pessah
      Molecular Pharmacology October 2020, 98 (4) 351-363; DOI: https://doi.org/10.1124/mol.120.119412

  7. Arttamangkul, Seksiri

    1. Chronic Treatment with Morphine Disrupts Acute Kinase-Dependent Desensitization of GPCRs
      Emily R. Leff, Seksiri Arttamangkul and John T. Williams
      Molecular Pharmacology October 2020, 98 (4) 497-507; DOI: https://doi.org/10.1124/mol.119.119362

B

  1. Bagley, E.E.

    1. Neprilysin Controls the Synaptic Activity of Neuropeptides in the Intercalated Cells of the Amygdala
      G.C. Gregoriou, S.D. Patel, B.L. Winters and E.E. Bagley
      Molecular Pharmacology October 2020, 98 (4) 454-461; DOI: https://doi.org/10.1124/mol.119.119370

  2. Barker, K.E.

    1. Spinal Opioid Tolerance Depends upon Platelet-Derived Growth Factor Receptor-β Signaling, Not μ-Opioid Receptor Internalization
      S. Puig, K.E. Barker, S.R. Szott, P.T. Kann, J.S. Morris and H.B. Gutstein
      Molecular Pharmacology October 2020, 98 (4) 487-496; DOI: https://doi.org/10.1124/mol.120.119552

  3. Barnett, Miriam E.

    1. Unique Pharmacological Properties of the Kappa Opioid Receptor Signaling Through Gαz as Shown with Bioluminescence Resonance Energy Transfer
      Miriam E. Barnett, Brian I. Knapp and Jean M. Bidlack
      Molecular Pharmacology October 2020, 98 (4) 462-474; DOI: https://doi.org/10.1124/mol.120.119404

  4. Bidlack, Jean M.

    1. Unique Pharmacological Properties of the Kappa Opioid Receptor Signaling Through Gαz as Shown with Bioluminescence Resonance Energy Transfer
      Miriam E. Barnett, Brian I. Knapp and Jean M. Bidlack
      Molecular Pharmacology October 2020, 98 (4) 462-474; DOI: https://doi.org/10.1124/mol.120.119404

  5. Birdsong, William T.

    1. Open Access
      Recent Progress in Opioid Research from an Electrophysiological Perspective
      William T. Birdsong and John T. Williams
      Molecular Pharmacology October 2020, 98 (4) 401-409; DOI: https://doi.org/10.1124/mol.119.119040

  6. Blendy, J.A.

    1. Open Access
      Bidirectional Relationship between Opioids and Disrupted Sleep: Putative Mechanisms
      D. Eacret, S.C. Veasey and J.A. Blendy
      Molecular Pharmacology October 2020, 98 (4) 445-453; DOI: https://doi.org/10.1124/mol.119.119107

  7. Burbridge, Ariel B.

    1. Analysis of Modulation of the ρ1 GABAA Receptor by Combinations of Inhibitory and Potentiating Neurosteroids Reveals Shared and Distinct Binding Sites
      Allison L. Germann, David E. Reichert, Ariel B. Burbridge, Spencer R. Pierce, Alex S. Evers, Joe Henry Steinbach and Gustav Akk
      Molecular Pharmacology October 2020, 98 (4) 280-291; DOI: https://doi.org/10.1124/mol.120.119842

  8. Burris, Thomas P.

    1. Weak Microbial Metabolites: a Treasure Trove for Using Biomimicry to Discover and Optimize Drugs
      Zdenek Dvorak, Max Klapholz, Thomas P. Burris, Benjamin P. Willing, Antimo Gioiello, Roberto Pellicciari, Francesco Galli, John March, Stephen J. O’Keefe, R. Balfour Sartor, Chang H. Kim, Maayan Levy and Sridhar Mani
      Molecular Pharmacology October 2020, 98 (4) 328-334; DOI: https://doi.org/10.1124/molpharm.120.000035
    2. Weak Microbial Metabolites: a Treasure Trove for Using Biomimicry to Discover and Optimize Drugs
      Zdenek Dvorak, Max Klapholz, Thomas P. Burris, Benjamin P. Willing, Antimo Gioiello, Roberto Pellicciari, Francesco Galli, John March, Stephen J. O’Keefe, R. Balfour Sartor, Chang H. Kim, Maayan Levy and Sridhar Mani
      Molecular Pharmacology October 2020, 98 (4) 343-349; DOI: https://doi.org/10.1124/molpharm.120.000035

C

  1. Canals, Meritxell

    1. Opioid Pharmacology under the Microscope
      Damien Jullié, Arisbel B. Gondin, Mark von Zastrow and Meritxell Canals
      Molecular Pharmacology October 2020, 98 (4) 425-432; DOI: https://doi.org/10.1124/mol.119.119321

  2. Carroll, F. Ivy

    1. Nicotinic Acetylcholine Receptor Accessory Subunits Determine the Activity Profile of Epibatidine Derivatives
      Lu Wenchi Corrie, Clare Stokes, Jenny L. Wilkerson, F. Ivy Carroll, Lance R. McMahon and Roger L. Papke
      Molecular Pharmacology October 2020, 98 (4) 328-342; DOI: https://doi.org/10.1124/molpharm.120.000037
    2. Nicotinic Acetylcholine Receptor Accessory Subunits Determine the Activity Profile of Epibatidine Derivatives
      Lu Wenchi Corrie, Clare Stokes, Jenny L. Wilkerson, F. Ivy Carroll, Lance R. McMahon and Roger L. Papke
      Molecular Pharmacology October 2020, 98 (4) 335-349; DOI: https://doi.org/10.1124/molpharm.120.000037

  3. Cherednichenko, Genady

    1. Dietary Caffeine Synergizes Adverse Peripheral and Central Responses to Anesthesia in Malignant Hyperthermia Susceptible Mice
      Monica Aleman, Rui Zhang, Wei Feng, Lihong Qi, Jose R. Lopez, Chelsea Crowe, Yao Dong, Genady Cherednichenko and Isaac N. Pessah
      Molecular Pharmacology October 2020, 98 (4) 351-363; DOI: https://doi.org/10.1124/mol.120.119412

  4. Christie, Macdonald J.

    1. Intrinsic Efficacy of Opioid Ligands and Its Importance for Apparent Bias, Operational Analysis, and Therapeutic Window
      Alexander Gillis, Varun Sreenivasan and Macdonald J. Christie
      Molecular Pharmacology October 2020, 98 (4) 410-424; DOI: https://doi.org/10.1124/mol.119.119214

  5. Corrie, Lu Wenchi

    1. Nicotinic Acetylcholine Receptor Accessory Subunits Determine the Activity Profile of Epibatidine Derivatives
      Lu Wenchi Corrie, Clare Stokes, Jenny L. Wilkerson, F. Ivy Carroll, Lance R. McMahon and Roger L. Papke
      Molecular Pharmacology October 2020, 98 (4) 328-342; DOI: https://doi.org/10.1124/molpharm.120.000037
    2. Nicotinic Acetylcholine Receptor Accessory Subunits Determine the Activity Profile of Epibatidine Derivatives
      Lu Wenchi Corrie, Clare Stokes, Jenny L. Wilkerson, F. Ivy Carroll, Lance R. McMahon and Roger L. Papke
      Molecular Pharmacology October 2020, 98 (4) 335-349; DOI: https://doi.org/10.1124/molpharm.120.000037

  6. Cox, Brian M.

    1. A Concise Review of Concepts in Opioid Pharmacology up to the Discovery of Endogenous Opioids
      Brian M. Cox
      Molecular Pharmacology October 2020, 98 (4) 392-400; DOI: https://doi.org/10.1124/mol.120.119420

  7. Crowe, Chelsea

    1. Dietary Caffeine Synergizes Adverse Peripheral and Central Responses to Anesthesia in Malignant Hyperthermia Susceptible Mice
      Monica Aleman, Rui Zhang, Wei Feng, Lihong Qi, Jose R. Lopez, Chelsea Crowe, Yao Dong, Genady Cherednichenko and Isaac N. Pessah
      Molecular Pharmacology October 2020, 98 (4) 351-363; DOI: https://doi.org/10.1124/mol.120.119412

  8. Curpan, Ramona F.

    1. Open Access
      Pharmacology and Molecular Mechanisms of Clinically Relevant Estrogen Estetrol and Estrogen Mimic BMI-135 for the Treatment of Endocrine-Resistant Breast Cancer
      Balkees Abderrahman, Philipp Y. Maximov, Ramona F. Curpan, Jay S. Hanspal, Ping Fan, Rui Xiong, Debra A. Tonetti, Gregory R.J. Thatcher and V. Craig Jordan
      Molecular Pharmacology October 2020, 98 (4) 363-380; DOI: https://doi.org/10.1124/molpharm.120.000054
    2. Open Access
      Pharmacology and Molecular Mechanisms of Clinically Relevant Estrogen Estetrol and Estrogen Mimic BMI-135 for the Treatment of Endocrine-Resistant Breast Cancer
      Balkees Abderrahman, Philipp Y. Maximov, Ramona F. Curpan, Jay S. Hanspal, Ping Fan, Rui Xiong, Debra A. Tonetti, Gregory R.J. Thatcher and V. Craig Jordan
      Molecular Pharmacology October 2020, 98 (4) 364-381; DOI: https://doi.org/10.1124/molpharm.120.000054

D

  1. Dong, Yao

    1. Dietary Caffeine Synergizes Adverse Peripheral and Central Responses to Anesthesia in Malignant Hyperthermia Susceptible Mice
      Monica Aleman, Rui Zhang, Wei Feng, Lihong Qi, Jose R. Lopez, Chelsea Crowe, Yao Dong, Genady Cherednichenko and Isaac N. Pessah
      Molecular Pharmacology October 2020, 98 (4) 351-363; DOI: https://doi.org/10.1124/mol.120.119412

  2. Dvorak, Zdenek

    1. Weak Microbial Metabolites: a Treasure Trove for Using Biomimicry to Discover and Optimize Drugs
      Zdenek Dvorak, Max Klapholz, Thomas P. Burris, Benjamin P. Willing, Antimo Gioiello, Roberto Pellicciari, Francesco Galli, John March, Stephen J. O’Keefe, R. Balfour Sartor, Chang H. Kim, Maayan Levy and Sridhar Mani
      Molecular Pharmacology October 2020, 98 (4) 328-334; DOI: https://doi.org/10.1124/molpharm.120.000035
    2. Weak Microbial Metabolites: a Treasure Trove for Using Biomimicry to Discover and Optimize Drugs
      Zdenek Dvorak, Max Klapholz, Thomas P. Burris, Benjamin P. Willing, Antimo Gioiello, Roberto Pellicciari, Francesco Galli, John March, Stephen J. O’Keefe, R. Balfour Sartor, Chang H. Kim, Maayan Levy and Sridhar Mani
      Molecular Pharmacology October 2020, 98 (4) 343-349; DOI: https://doi.org/10.1124/molpharm.120.000035

E

  1. Eacret, D.

    1. Open Access
      Bidirectional Relationship between Opioids and Disrupted Sleep: Putative Mechanisms
      D. Eacret, S.C. Veasey and J.A. Blendy
      Molecular Pharmacology October 2020, 98 (4) 445-453; DOI: https://doi.org/10.1124/mol.119.119107

  2. El Mestikawy, Salah

    1. Targeting Vesicular Glutamate Transporter Machinery: Implications on Metabotropic Glutamate Receptor 5 Signaling and Behavior
      Karim S. Ibrahim, Khaled S. Abd-Elrahman, Salah El Mestikawy and Stephen S.G. Ferguson
      Molecular Pharmacology October 2020, 98 (4) 315-328; DOI: https://doi.org/10.1124/mol.120.000089
    2. Targeting Vesicular Glutamate Transporter Machinery: Implications on Metabotropic Glutamate Receptor 5 Signaling and Behavior
      Karim S. Ibrahim, Khaled S. Abd-Elrahman, Salah El Mestikawy and Stephen S.G. Ferguson
      Molecular Pharmacology October 2020, 98 (4) 314-327; DOI: https://doi.org/10.1124/molpharm.120.000089

  3. Evers, Alex S.

    1. Analysis of Modulation of the ρ1 GABAA Receptor by Combinations of Inhibitory and Potentiating Neurosteroids Reveals Shared and Distinct Binding Sites
      Allison L. Germann, David E. Reichert, Ariel B. Burbridge, Spencer R. Pierce, Alex S. Evers, Joe Henry Steinbach and Gustav Akk
      Molecular Pharmacology October 2020, 98 (4) 280-291; DOI: https://doi.org/10.1124/mol.120.119842
    2. Enhancement of Muscimol Binding and Gating by Allosteric Modulators of the GABAA Receptor: Relating Occupancy to State Functions
      Gustav Akk, Allison L. Germann, Yusuke Sugasawa, Spencer R. Pierce, Alex S. Evers and Joe Henry Steinbach
      Molecular Pharmacology October 2020, 98 (4) 303-313; DOI: https://doi.org/10.1124/molpharm.120.000066

F

  1. Fan, Ping

    1. Open Access
      Pharmacology and Molecular Mechanisms of Clinically Relevant Estrogen Estetrol and Estrogen Mimic BMI-135 for the Treatment of Endocrine-Resistant Breast Cancer
      Balkees Abderrahman, Philipp Y. Maximov, Ramona F. Curpan, Jay S. Hanspal, Ping Fan, Rui Xiong, Debra A. Tonetti, Gregory R.J. Thatcher and V. Craig Jordan
      Molecular Pharmacology October 2020, 98 (4) 363-380; DOI: https://doi.org/10.1124/molpharm.120.000054
    2. Open Access
      Pharmacology and Molecular Mechanisms of Clinically Relevant Estrogen Estetrol and Estrogen Mimic BMI-135 for the Treatment of Endocrine-Resistant Breast Cancer
      Balkees Abderrahman, Philipp Y. Maximov, Ramona F. Curpan, Jay S. Hanspal, Ping Fan, Rui Xiong, Debra A. Tonetti, Gregory R.J. Thatcher and V. Craig Jordan
      Molecular Pharmacology October 2020, 98 (4) 364-381; DOI: https://doi.org/10.1124/molpharm.120.000054

  2. Feng, Wei

    1. Dietary Caffeine Synergizes Adverse Peripheral and Central Responses to Anesthesia in Malignant Hyperthermia Susceptible Mice
      Monica Aleman, Rui Zhang, Wei Feng, Lihong Qi, Jose R. Lopez, Chelsea Crowe, Yao Dong, Genady Cherednichenko and Isaac N. Pessah
      Molecular Pharmacology October 2020, 98 (4) 351-363; DOI: https://doi.org/10.1124/mol.120.119412

  3. Ferguson, Stephen S.G.

    1. Targeting Vesicular Glutamate Transporter Machinery: Implications on Metabotropic Glutamate Receptor 5 Signaling and Behavior
      Karim S. Ibrahim, Khaled S. Abd-Elrahman, Salah El Mestikawy and Stephen S.G. Ferguson
      Molecular Pharmacology October 2020, 98 (4) 315-328; DOI: https://doi.org/10.1124/mol.120.000089
    2. Targeting Vesicular Glutamate Transporter Machinery: Implications on Metabotropic Glutamate Receptor 5 Signaling and Behavior
      Karim S. Ibrahim, Khaled S. Abd-Elrahman, Salah El Mestikawy and Stephen S.G. Ferguson
      Molecular Pharmacology October 2020, 98 (4) 314-327; DOI: https://doi.org/10.1124/molpharm.120.000089

  4. Filizola, Marta

    1. Open Access
      Atomic-Level Characterization of the Methadone-Stabilized Active Conformation of µ-Opioid Receptor
      Abhijeet Kapoor, Davide Provasi and Marta Filizola
      Molecular Pharmacology October 2020, 98 (4) 475-486; DOI: https://doi.org/10.1124/mol.119.119339

G

  1. Galli, Francesco

    1. Weak Microbial Metabolites: a Treasure Trove for Using Biomimicry to Discover and Optimize Drugs
      Zdenek Dvorak, Max Klapholz, Thomas P. Burris, Benjamin P. Willing, Antimo Gioiello, Roberto Pellicciari, Francesco Galli, John March, Stephen J. O’Keefe, R. Balfour Sartor, Chang H. Kim, Maayan Levy and Sridhar Mani
      Molecular Pharmacology October 2020, 98 (4) 328-334; DOI: https://doi.org/10.1124/molpharm.120.000035
    2. Weak Microbial Metabolites: a Treasure Trove for Using Biomimicry to Discover and Optimize Drugs
      Zdenek Dvorak, Max Klapholz, Thomas P. Burris, Benjamin P. Willing, Antimo Gioiello, Roberto Pellicciari, Francesco Galli, John March, Stephen J. O’Keefe, R. Balfour Sartor, Chang H. Kim, Maayan Levy and Sridhar Mani
      Molecular Pharmacology October 2020, 98 (4) 343-349; DOI: https://doi.org/10.1124/molpharm.120.000035

  2. Garai, Sumanta

    1. Differing Activity Profiles of the Stereoisomers of 2,3,5,6TMP-TQS, a Putative Silent Allosteric Modulator of α7 nAChR
      Roger L. Papke, Sumanta Garai, Clare Stokes, Nicole A. Horenstein, Arthur D. Zimmerman, Khalil A. Abboud and Ganesh A. Thakur
      Molecular Pharmacology October 2020, 98 (4) 292-302; DOI: https://doi.org/10.1124/mol.120.119958

  3. Germann, Allison L.

    1. Analysis of Modulation of the ρ1 GABAA Receptor by Combinations of Inhibitory and Potentiating Neurosteroids Reveals Shared and Distinct Binding Sites
      Allison L. Germann, David E. Reichert, Ariel B. Burbridge, Spencer R. Pierce, Alex S. Evers, Joe Henry Steinbach and Gustav Akk
      Molecular Pharmacology October 2020, 98 (4) 280-291; DOI: https://doi.org/10.1124/mol.120.119842
    2. Enhancement of Muscimol Binding and Gating by Allosteric Modulators of the GABAA Receptor: Relating Occupancy to State Functions
      Gustav Akk, Allison L. Germann, Yusuke Sugasawa, Spencer R. Pierce, Alex S. Evers and Joe Henry Steinbach
      Molecular Pharmacology October 2020, 98 (4) 303-313; DOI: https://doi.org/10.1124/molpharm.120.000066

  4. Gewirtz, David A.

    1. “Emerging Concepts”: New Article Category in Molecular Pharmacology
      David A. Gewirtz
      Molecular Pharmacology October 2020, 98 (4) 350; DOI: https://doi.org/10.1124/molpharm.120.000133

  5. Gillis, Alexander

    1. Intrinsic Efficacy of Opioid Ligands and Its Importance for Apparent Bias, Operational Analysis, and Therapeutic Window
      Alexander Gillis, Varun Sreenivasan and Macdonald J. Christie
      Molecular Pharmacology October 2020, 98 (4) 410-424; DOI: https://doi.org/10.1124/mol.119.119214

  6. Gioiello, Antimo

    1. Weak Microbial Metabolites: a Treasure Trove for Using Biomimicry to Discover and Optimize Drugs
      Zdenek Dvorak, Max Klapholz, Thomas P. Burris, Benjamin P. Willing, Antimo Gioiello, Roberto Pellicciari, Francesco Galli, John March, Stephen J. O’Keefe, R. Balfour Sartor, Chang H. Kim, Maayan Levy and Sridhar Mani
      Molecular Pharmacology October 2020, 98 (4) 328-334; DOI: https://doi.org/10.1124/molpharm.120.000035
    2. Weak Microbial Metabolites: a Treasure Trove for Using Biomimicry to Discover and Optimize Drugs
      Zdenek Dvorak, Max Klapholz, Thomas P. Burris, Benjamin P. Willing, Antimo Gioiello, Roberto Pellicciari, Francesco Galli, John March, Stephen J. O’Keefe, R. Balfour Sartor, Chang H. Kim, Maayan Levy and Sridhar Mani
      Molecular Pharmacology October 2020, 98 (4) 343-349; DOI: https://doi.org/10.1124/molpharm.120.000035

  7. Gondin, Arisbel B.

    1. Opioid Pharmacology under the Microscope
      Damien Jullié, Arisbel B. Gondin, Mark von Zastrow and Meritxell Canals
      Molecular Pharmacology October 2020, 98 (4) 425-432; DOI: https://doi.org/10.1124/mol.119.119321

  8. Gregoriou, G.C.

    1. Neprilysin Controls the Synaptic Activity of Neuropeptides in the Intercalated Cells of the Amygdala
      G.C. Gregoriou, S.D. Patel, B.L. Winters and E.E. Bagley
      Molecular Pharmacology October 2020, 98 (4) 454-461; DOI: https://doi.org/10.1124/mol.119.119370

  9. Gutstein, H.B.

    1. Spinal Opioid Tolerance Depends upon Platelet-Derived Growth Factor Receptor-β Signaling, Not μ-Opioid Receptor Internalization
      S. Puig, K.E. Barker, S.R. Szott, P.T. Kann, J.S. Morris and H.B. Gutstein
      Molecular Pharmacology October 2020, 98 (4) 487-496; DOI: https://doi.org/10.1124/mol.120.119552

H

  1. Hanspal, Jay S.

    1. Open Access
      Pharmacology and Molecular Mechanisms of Clinically Relevant Estrogen Estetrol and Estrogen Mimic BMI-135 for the Treatment of Endocrine-Resistant Breast Cancer
      Balkees Abderrahman, Philipp Y. Maximov, Ramona F. Curpan, Jay S. Hanspal, Ping Fan, Rui Xiong, Debra A. Tonetti, Gregory R.J. Thatcher and V. Craig Jordan
      Molecular Pharmacology October 2020, 98 (4) 363-380; DOI: https://doi.org/10.1124/molpharm.120.000054
    2. Open Access
      Pharmacology and Molecular Mechanisms of Clinically Relevant Estrogen Estetrol and Estrogen Mimic BMI-135 for the Treatment of Endocrine-Resistant Breast Cancer
      Balkees Abderrahman, Philipp Y. Maximov, Ramona F. Curpan, Jay S. Hanspal, Ping Fan, Rui Xiong, Debra A. Tonetti, Gregory R.J. Thatcher and V. Craig Jordan
      Molecular Pharmacology October 2020, 98 (4) 364-381; DOI: https://doi.org/10.1124/molpharm.120.000054

  2. Horenstein, Nicole A.

    1. Differing Activity Profiles of the Stereoisomers of 2,3,5,6TMP-TQS, a Putative Silent Allosteric Modulator of α7 nAChR
      Roger L. Papke, Sumanta Garai, Clare Stokes, Nicole A. Horenstein, Arthur D. Zimmerman, Khalil A. Abboud and Ganesh A. Thakur
      Molecular Pharmacology October 2020, 98 (4) 292-302; DOI: https://doi.org/10.1124/mol.120.119958

I

  1. Ibrahim, Karim S.

    1. Targeting Vesicular Glutamate Transporter Machinery: Implications on Metabotropic Glutamate Receptor 5 Signaling and Behavior
      Karim S. Ibrahim, Khaled S. Abd-Elrahman, Salah El Mestikawy and Stephen S.G. Ferguson
      Molecular Pharmacology October 2020, 98 (4) 315-328; DOI: https://doi.org/10.1124/mol.120.000089
    2. Targeting Vesicular Glutamate Transporter Machinery: Implications on Metabotropic Glutamate Receptor 5 Signaling and Behavior
      Karim S. Ibrahim, Khaled S. Abd-Elrahman, Salah El Mestikawy and Stephen S.G. Ferguson
      Molecular Pharmacology October 2020, 98 (4) 314-327; DOI: https://doi.org/10.1124/molpharm.120.000089

J

  1. Jordan, V. Craig

    1. Open Access
      Pharmacology and Molecular Mechanisms of Clinically Relevant Estrogen Estetrol and Estrogen Mimic BMI-135 for the Treatment of Endocrine-Resistant Breast Cancer
      Balkees Abderrahman, Philipp Y. Maximov, Ramona F. Curpan, Jay S. Hanspal, Ping Fan, Rui Xiong, Debra A. Tonetti, Gregory R.J. Thatcher and V. Craig Jordan
      Molecular Pharmacology October 2020, 98 (4) 363-380; DOI: https://doi.org/10.1124/molpharm.120.000054
    2. Open Access
      Pharmacology and Molecular Mechanisms of Clinically Relevant Estrogen Estetrol and Estrogen Mimic BMI-135 for the Treatment of Endocrine-Resistant Breast Cancer
      Balkees Abderrahman, Philipp Y. Maximov, Ramona F. Curpan, Jay S. Hanspal, Ping Fan, Rui Xiong, Debra A. Tonetti, Gregory R.J. Thatcher and V. Craig Jordan
      Molecular Pharmacology October 2020, 98 (4) 364-381; DOI: https://doi.org/10.1124/molpharm.120.000054

  2. Jullié, Damien

    1. Opioid Pharmacology under the Microscope
      Damien Jullié, Arisbel B. Gondin, Mark von Zastrow and Meritxell Canals
      Molecular Pharmacology October 2020, 98 (4) 425-432; DOI: https://doi.org/10.1124/mol.119.119321

K

  1. Kabbani, N.

    1. Response to Comments on “Does COVID19 Infect the Brain? If So, Smokers Might Be at a Higher Risk”
      N. Kabbani and J.L. Olds
      Molecular Pharmacology October 2020, 98 (4) 384-385; DOI: https://doi.org/10.1124/molpharm.120.000120

  2. Kann, P.T.

    1. Spinal Opioid Tolerance Depends upon Platelet-Derived Growth Factor Receptor-β Signaling, Not μ-Opioid Receptor Internalization
      S. Puig, K.E. Barker, S.R. Szott, P.T. Kann, J.S. Morris and H.B. Gutstein
      Molecular Pharmacology October 2020, 98 (4) 487-496; DOI: https://doi.org/10.1124/mol.120.119552

  3. Kapoor, Abhijeet

    1. Open Access
      Atomic-Level Characterization of the Methadone-Stabilized Active Conformation of µ-Opioid Receptor
      Abhijeet Kapoor, Davide Provasi and Marta Filizola
      Molecular Pharmacology October 2020, 98 (4) 475-486; DOI: https://doi.org/10.1124/mol.119.119339

  4. Kim, Chang H.

    1. Weak Microbial Metabolites: a Treasure Trove for Using Biomimicry to Discover and Optimize Drugs
      Zdenek Dvorak, Max Klapholz, Thomas P. Burris, Benjamin P. Willing, Antimo Gioiello, Roberto Pellicciari, Francesco Galli, John March, Stephen J. O’Keefe, R. Balfour Sartor, Chang H. Kim, Maayan Levy and Sridhar Mani
      Molecular Pharmacology October 2020, 98 (4) 328-334; DOI: https://doi.org/10.1124/molpharm.120.000035
    2. Weak Microbial Metabolites: a Treasure Trove for Using Biomimicry to Discover and Optimize Drugs
      Zdenek Dvorak, Max Klapholz, Thomas P. Burris, Benjamin P. Willing, Antimo Gioiello, Roberto Pellicciari, Francesco Galli, John March, Stephen J. O’Keefe, R. Balfour Sartor, Chang H. Kim, Maayan Levy and Sridhar Mani
      Molecular Pharmacology October 2020, 98 (4) 343-349; DOI: https://doi.org/10.1124/molpharm.120.000035

  5. Klapholz, Max

    1. Weak Microbial Metabolites: a Treasure Trove for Using Biomimicry to Discover and Optimize Drugs
      Zdenek Dvorak, Max Klapholz, Thomas P. Burris, Benjamin P. Willing, Antimo Gioiello, Roberto Pellicciari, Francesco Galli, John March, Stephen J. O’Keefe, R. Balfour Sartor, Chang H. Kim, Maayan Levy and Sridhar Mani
      Molecular Pharmacology October 2020, 98 (4) 328-334; DOI: https://doi.org/10.1124/molpharm.120.000035
    2. Weak Microbial Metabolites: a Treasure Trove for Using Biomimicry to Discover and Optimize Drugs
      Zdenek Dvorak, Max Klapholz, Thomas P. Burris, Benjamin P. Willing, Antimo Gioiello, Roberto Pellicciari, Francesco Galli, John March, Stephen J. O’Keefe, R. Balfour Sartor, Chang H. Kim, Maayan Levy and Sridhar Mani
      Molecular Pharmacology October 2020, 98 (4) 343-349; DOI: https://doi.org/10.1124/molpharm.120.000035

  6. Knapp, Brian I.

    1. Unique Pharmacological Properties of the Kappa Opioid Receptor Signaling Through Gαz as Shown with Bioluminescence Resonance Energy Transfer
      Miriam E. Barnett, Brian I. Knapp and Jean M. Bidlack
      Molecular Pharmacology October 2020, 98 (4) 462-474; DOI: https://doi.org/10.1124/mol.120.119404

L

  1. Leff, Emily R.

    1. Chronic Treatment with Morphine Disrupts Acute Kinase-Dependent Desensitization of GPCRs
      Emily R. Leff, Seksiri Arttamangkul and John T. Williams
      Molecular Pharmacology October 2020, 98 (4) 497-507; DOI: https://doi.org/10.1124/mol.119.119362

  2. Levy, Maayan

    1. Weak Microbial Metabolites: a Treasure Trove for Using Biomimicry to Discover and Optimize Drugs
      Zdenek Dvorak, Max Klapholz, Thomas P. Burris, Benjamin P. Willing, Antimo Gioiello, Roberto Pellicciari, Francesco Galli, John March, Stephen J. O’Keefe, R. Balfour Sartor, Chang H. Kim, Maayan Levy and Sridhar Mani
      Molecular Pharmacology October 2020, 98 (4) 328-334; DOI: https://doi.org/10.1124/molpharm.120.000035
    2. Weak Microbial Metabolites: a Treasure Trove for Using Biomimicry to Discover and Optimize Drugs
      Zdenek Dvorak, Max Klapholz, Thomas P. Burris, Benjamin P. Willing, Antimo Gioiello, Roberto Pellicciari, Francesco Galli, John March, Stephen J. O’Keefe, R. Balfour Sartor, Chang H. Kim, Maayan Levy and Sridhar Mani
      Molecular Pharmacology October 2020, 98 (4) 343-349; DOI: https://doi.org/10.1124/molpharm.120.000035

  3. Lopez, Jose R.

    1. Dietary Caffeine Synergizes Adverse Peripheral and Central Responses to Anesthesia in Malignant Hyperthermia Susceptible Mice
      Monica Aleman, Rui Zhang, Wei Feng, Lihong Qi, Jose R. Lopez, Chelsea Crowe, Yao Dong, Genady Cherednichenko and Isaac N. Pessah
      Molecular Pharmacology October 2020, 98 (4) 351-363; DOI: https://doi.org/10.1124/mol.120.119412

M

  1. Mani, Sridhar

    1. Weak Microbial Metabolites: a Treasure Trove for Using Biomimicry to Discover and Optimize Drugs
      Zdenek Dvorak, Max Klapholz, Thomas P. Burris, Benjamin P. Willing, Antimo Gioiello, Roberto Pellicciari, Francesco Galli, John March, Stephen J. O’Keefe, R. Balfour Sartor, Chang H. Kim, Maayan Levy and Sridhar Mani
      Molecular Pharmacology October 2020, 98 (4) 328-334; DOI: https://doi.org/10.1124/molpharm.120.000035
    2. Weak Microbial Metabolites: a Treasure Trove for Using Biomimicry to Discover and Optimize Drugs
      Zdenek Dvorak, Max Klapholz, Thomas P. Burris, Benjamin P. Willing, Antimo Gioiello, Roberto Pellicciari, Francesco Galli, John March, Stephen J. O’Keefe, R. Balfour Sartor, Chang H. Kim, Maayan Levy and Sridhar Mani
      Molecular Pharmacology October 2020, 98 (4) 343-349; DOI: https://doi.org/10.1124/molpharm.120.000035

  2. March, John

    1. Weak Microbial Metabolites: a Treasure Trove for Using Biomimicry to Discover and Optimize Drugs
      Zdenek Dvorak, Max Klapholz, Thomas P. Burris, Benjamin P. Willing, Antimo Gioiello, Roberto Pellicciari, Francesco Galli, John March, Stephen J. O’Keefe, R. Balfour Sartor, Chang H. Kim, Maayan Levy and Sridhar Mani
      Molecular Pharmacology October 2020, 98 (4) 328-334; DOI: https://doi.org/10.1124/molpharm.120.000035
    2. Weak Microbial Metabolites: a Treasure Trove for Using Biomimicry to Discover and Optimize Drugs
      Zdenek Dvorak, Max Klapholz, Thomas P. Burris, Benjamin P. Willing, Antimo Gioiello, Roberto Pellicciari, Francesco Galli, John March, Stephen J. O’Keefe, R. Balfour Sartor, Chang H. Kim, Maayan Levy and Sridhar Mani
      Molecular Pharmacology October 2020, 98 (4) 343-349; DOI: https://doi.org/10.1124/molpharm.120.000035

  3. Maximov, Philipp Y.

    1. Open Access
      Pharmacology and Molecular Mechanisms of Clinically Relevant Estrogen Estetrol and Estrogen Mimic BMI-135 for the Treatment of Endocrine-Resistant Breast Cancer
      Balkees Abderrahman, Philipp Y. Maximov, Ramona F. Curpan, Jay S. Hanspal, Ping Fan, Rui Xiong, Debra A. Tonetti, Gregory R.J. Thatcher and V. Craig Jordan
      Molecular Pharmacology October 2020, 98 (4) 363-380; DOI: https://doi.org/10.1124/molpharm.120.000054
    2. Open Access
      Pharmacology and Molecular Mechanisms of Clinically Relevant Estrogen Estetrol and Estrogen Mimic BMI-135 for the Treatment of Endocrine-Resistant Breast Cancer
      Balkees Abderrahman, Philipp Y. Maximov, Ramona F. Curpan, Jay S. Hanspal, Ping Fan, Rui Xiong, Debra A. Tonetti, Gregory R.J. Thatcher and V. Craig Jordan
      Molecular Pharmacology October 2020, 98 (4) 364-381; DOI: https://doi.org/10.1124/molpharm.120.000054

  4. McMahon, Lance R.

    1. Nicotinic Acetylcholine Receptor Accessory Subunits Determine the Activity Profile of Epibatidine Derivatives
      Lu Wenchi Corrie, Clare Stokes, Jenny L. Wilkerson, F. Ivy Carroll, Lance R. McMahon and Roger L. Papke
      Molecular Pharmacology October 2020, 98 (4) 328-342; DOI: https://doi.org/10.1124/molpharm.120.000037
    2. Nicotinic Acetylcholine Receptor Accessory Subunits Determine the Activity Profile of Epibatidine Derivatives
      Lu Wenchi Corrie, Clare Stokes, Jenny L. Wilkerson, F. Ivy Carroll, Lance R. McMahon and Roger L. Papke
      Molecular Pharmacology October 2020, 98 (4) 335-349; DOI: https://doi.org/10.1124/molpharm.120.000037

  5. Morris, J.S.

    1. Spinal Opioid Tolerance Depends upon Platelet-Derived Growth Factor Receptor-β Signaling, Not μ-Opioid Receptor Internalization
      S. Puig, K.E. Barker, S.R. Szott, P.T. Kann, J.S. Morris and H.B. Gutstein
      Molecular Pharmacology October 2020, 98 (4) 487-496; DOI: https://doi.org/10.1124/mol.120.119552

O

  1. O’Keefe, Stephen J.

    1. Weak Microbial Metabolites: a Treasure Trove for Using Biomimicry to Discover and Optimize Drugs
      Zdenek Dvorak, Max Klapholz, Thomas P. Burris, Benjamin P. Willing, Antimo Gioiello, Roberto Pellicciari, Francesco Galli, John March, Stephen J. O’Keefe, R. Balfour Sartor, Chang H. Kim, Maayan Levy and Sridhar Mani
      Molecular Pharmacology October 2020, 98 (4) 328-334; DOI: https://doi.org/10.1124/molpharm.120.000035
    2. Weak Microbial Metabolites: a Treasure Trove for Using Biomimicry to Discover and Optimize Drugs
      Zdenek Dvorak, Max Klapholz, Thomas P. Burris, Benjamin P. Willing, Antimo Gioiello, Roberto Pellicciari, Francesco Galli, John March, Stephen J. O’Keefe, R. Balfour Sartor, Chang H. Kim, Maayan Levy and Sridhar Mani
      Molecular Pharmacology October 2020, 98 (4) 343-349; DOI: https://doi.org/10.1124/molpharm.120.000035

  2. Olds, J.L.

    1. Response to Comments on “Does COVID19 Infect the Brain? If So, Smokers Might Be at a Higher Risk”
      N. Kabbani and J.L. Olds
      Molecular Pharmacology October 2020, 98 (4) 384-385; DOI: https://doi.org/10.1124/molpharm.120.000120

P

  1. Pan, Ying-Xian

    1. A Truncated Six Transmembrane Splice Variant MOR-1G Enhances Expression of the Full-Length Seven Transmembrane μ-Opioid Receptor through Heterodimerization
      Tiffany Zhang, Jin Xu and Ying-Xian Pan
      Molecular Pharmacology October 2020, 98 (4) 518-527; DOI: https://doi.org/10.1124/mol.120.119453

  2. Papke, Roger L.

    1. Differing Activity Profiles of the Stereoisomers of 2,3,5,6TMP-TQS, a Putative Silent Allosteric Modulator of α7 nAChR
      Roger L. Papke, Sumanta Garai, Clare Stokes, Nicole A. Horenstein, Arthur D. Zimmerman, Khalil A. Abboud and Ganesh A. Thakur
      Molecular Pharmacology October 2020, 98 (4) 292-302; DOI: https://doi.org/10.1124/mol.120.119958
    2. Nicotinic Acetylcholine Receptor Accessory Subunits Determine the Activity Profile of Epibatidine Derivatives
      Lu Wenchi Corrie, Clare Stokes, Jenny L. Wilkerson, F. Ivy Carroll, Lance R. McMahon and Roger L. Papke
      Molecular Pharmacology October 2020, 98 (4) 328-342; DOI: https://doi.org/10.1124/molpharm.120.000037
    3. Nicotinic Acetylcholine Receptor Accessory Subunits Determine the Activity Profile of Epibatidine Derivatives
      Lu Wenchi Corrie, Clare Stokes, Jenny L. Wilkerson, F. Ivy Carroll, Lance R. McMahon and Roger L. Papke
      Molecular Pharmacology October 2020, 98 (4) 335-349; DOI: https://doi.org/10.1124/molpharm.120.000037

  3. Parker, Kyle E.

    1. Pain, Motivation, Migraine, and the Microbiome: New Frontiers for Opioid Systems and Disease
      Kyle E. Parker, Elizabeth Sugiarto, Anna M.W. Taylor, Amynah A. Pradhan and Ream Al-Hasani
      Molecular Pharmacology October 2020, 98 (4) 433-444; DOI: https://doi.org/10.1124/mol.120.119438

  4. Patel, S.D.

    1. Neprilysin Controls the Synaptic Activity of Neuropeptides in the Intercalated Cells of the Amygdala
      G.C. Gregoriou, S.D. Patel, B.L. Winters and E.E. Bagley
      Molecular Pharmacology October 2020, 98 (4) 454-461; DOI: https://doi.org/10.1124/mol.119.119370

  5. Pellicciari, Roberto

    1. Weak Microbial Metabolites: a Treasure Trove for Using Biomimicry to Discover and Optimize Drugs
      Zdenek Dvorak, Max Klapholz, Thomas P. Burris, Benjamin P. Willing, Antimo Gioiello, Roberto Pellicciari, Francesco Galli, John March, Stephen J. O’Keefe, R. Balfour Sartor, Chang H. Kim, Maayan Levy and Sridhar Mani
      Molecular Pharmacology October 2020, 98 (4) 328-334; DOI: https://doi.org/10.1124/molpharm.120.000035
    2. Weak Microbial Metabolites: a Treasure Trove for Using Biomimicry to Discover and Optimize Drugs
      Zdenek Dvorak, Max Klapholz, Thomas P. Burris, Benjamin P. Willing, Antimo Gioiello, Roberto Pellicciari, Francesco Galli, John March, Stephen J. O’Keefe, R. Balfour Sartor, Chang H. Kim, Maayan Levy and Sridhar Mani
      Molecular Pharmacology October 2020, 98 (4) 343-349; DOI: https://doi.org/10.1124/molpharm.120.000035

  6. Pessah, Isaac N.

    1. Dietary Caffeine Synergizes Adverse Peripheral and Central Responses to Anesthesia in Malignant Hyperthermia Susceptible Mice
      Monica Aleman, Rui Zhang, Wei Feng, Lihong Qi, Jose R. Lopez, Chelsea Crowe, Yao Dong, Genady Cherednichenko and Isaac N. Pessah
      Molecular Pharmacology October 2020, 98 (4) 351-363; DOI: https://doi.org/10.1124/mol.120.119412

  7. Pierce, Spencer R.

    1. Analysis of Modulation of the ρ1 GABAA Receptor by Combinations of Inhibitory and Potentiating Neurosteroids Reveals Shared and Distinct Binding Sites
      Allison L. Germann, David E. Reichert, Ariel B. Burbridge, Spencer R. Pierce, Alex S. Evers, Joe Henry Steinbach and Gustav Akk
      Molecular Pharmacology October 2020, 98 (4) 280-291; DOI: https://doi.org/10.1124/mol.120.119842
    2. Enhancement of Muscimol Binding and Gating by Allosteric Modulators of the GABAA Receptor: Relating Occupancy to State Functions
      Gustav Akk, Allison L. Germann, Yusuke Sugasawa, Spencer R. Pierce, Alex S. Evers and Joe Henry Steinbach
      Molecular Pharmacology October 2020, 98 (4) 303-313; DOI: https://doi.org/10.1124/molpharm.120.000066

  8. Pradhan, Amynah A.

    1. Pain, Motivation, Migraine, and the Microbiome: New Frontiers for Opioid Systems and Disease
      Kyle E. Parker, Elizabeth Sugiarto, Anna M.W. Taylor, Amynah A. Pradhan and Ream Al-Hasani
      Molecular Pharmacology October 2020, 98 (4) 433-444; DOI: https://doi.org/10.1124/mol.120.119438

  9. Provasi, Davide

    1. Open Access
      Atomic-Level Characterization of the Methadone-Stabilized Active Conformation of µ-Opioid Receptor
      Abhijeet Kapoor, Davide Provasi and Marta Filizola
      Molecular Pharmacology October 2020, 98 (4) 475-486; DOI: https://doi.org/10.1124/mol.119.119339

  10. Puig, S.

    1. Spinal Opioid Tolerance Depends upon Platelet-Derived Growth Factor Receptor-β Signaling, Not μ-Opioid Receptor Internalization
      S. Puig, K.E. Barker, S.R. Szott, P.T. Kann, J.S. Morris and H.B. Gutstein
      Molecular Pharmacology October 2020, 98 (4) 487-496; DOI: https://doi.org/10.1124/mol.120.119552

  11. Puthenveedu, Manojkumar A.

    1. Editorial: 50 Years of Opioid Research and the International Narcotics Research Conference
      Manojkumar A. Puthenveedu
      Molecular Pharmacology October 2020, 98 (4) 386-388; DOI: https://doi.org/10.1124/molpharm.120.000132

Q

  1. Qi, Lihong

    1. Dietary Caffeine Synergizes Adverse Peripheral and Central Responses to Anesthesia in Malignant Hyperthermia Susceptible Mice
      Monica Aleman, Rui Zhang, Wei Feng, Lihong Qi, Jose R. Lopez, Chelsea Crowe, Yao Dong, Genady Cherednichenko and Isaac N. Pessah
      Molecular Pharmacology October 2020, 98 (4) 351-363; DOI: https://doi.org/10.1124/mol.120.119412

R

  1. Reichert, David E.

    1. Analysis of Modulation of the ρ1 GABAA Receptor by Combinations of Inhibitory and Potentiating Neurosteroids Reveals Shared and Distinct Binding Sites
      Allison L. Germann, David E. Reichert, Ariel B. Burbridge, Spencer R. Pierce, Alex S. Evers, Joe Henry Steinbach and Gustav Akk
      Molecular Pharmacology October 2020, 98 (4) 280-291; DOI: https://doi.org/10.1124/mol.120.119842

S

  1. Sartor, R. Balfour

    1. Weak Microbial Metabolites: a Treasure Trove for Using Biomimicry to Discover and Optimize Drugs
      Zdenek Dvorak, Max Klapholz, Thomas P. Burris, Benjamin P. Willing, Antimo Gioiello, Roberto Pellicciari, Francesco Galli, John March, Stephen J. O’Keefe, R. Balfour Sartor, Chang H. Kim, Maayan Levy and Sridhar Mani
      Molecular Pharmacology October 2020, 98 (4) 328-334; DOI: https://doi.org/10.1124/molpharm.120.000035
    2. Weak Microbial Metabolites: a Treasure Trove for Using Biomimicry to Discover and Optimize Drugs
      Zdenek Dvorak, Max Klapholz, Thomas P. Burris, Benjamin P. Willing, Antimo Gioiello, Roberto Pellicciari, Francesco Galli, John March, Stephen J. O’Keefe, R. Balfour Sartor, Chang H. Kim, Maayan Levy and Sridhar Mani
      Molecular Pharmacology October 2020, 98 (4) 343-349; DOI: https://doi.org/10.1124/molpharm.120.000035

  2. Speth, Robert C.

    1. Commentary on: “Does COVID19 Infect the Brain? If So, Smokers Might Be at a Higher Risk”
      Robert C. Speth
      Molecular Pharmacology October 2020, 98 (4) 382-383; DOI: https://doi.org/10.1124/molpharm.120.000049

  3. Sreenivasan, Varun

    1. Intrinsic Efficacy of Opioid Ligands and Its Importance for Apparent Bias, Operational Analysis, and Therapeutic Window
      Alexander Gillis, Varun Sreenivasan and Macdonald J. Christie
      Molecular Pharmacology October 2020, 98 (4) 410-424; DOI: https://doi.org/10.1124/mol.119.119214

  4. Steinbach, Joe Henry

    1. Analysis of Modulation of the ρ1 GABAA Receptor by Combinations of Inhibitory and Potentiating Neurosteroids Reveals Shared and Distinct Binding Sites
      Allison L. Germann, David E. Reichert, Ariel B. Burbridge, Spencer R. Pierce, Alex S. Evers, Joe Henry Steinbach and Gustav Akk
      Molecular Pharmacology October 2020, 98 (4) 280-291; DOI: https://doi.org/10.1124/mol.120.119842
    2. Enhancement of Muscimol Binding and Gating by Allosteric Modulators of the GABAA Receptor: Relating Occupancy to State Functions
      Gustav Akk, Allison L. Germann, Yusuke Sugasawa, Spencer R. Pierce, Alex S. Evers and Joe Henry Steinbach
      Molecular Pharmacology October 2020, 98 (4) 303-313; DOI: https://doi.org/10.1124/molpharm.120.000066

  5. Stokes, Clare

    1. Differing Activity Profiles of the Stereoisomers of 2,3,5,6TMP-TQS, a Putative Silent Allosteric Modulator of α7 nAChR
      Roger L. Papke, Sumanta Garai, Clare Stokes, Nicole A. Horenstein, Arthur D. Zimmerman, Khalil A. Abboud and Ganesh A. Thakur
      Molecular Pharmacology October 2020, 98 (4) 292-302; DOI: https://doi.org/10.1124/mol.120.119958
    2. Nicotinic Acetylcholine Receptor Accessory Subunits Determine the Activity Profile of Epibatidine Derivatives
      Lu Wenchi Corrie, Clare Stokes, Jenny L. Wilkerson, F. Ivy Carroll, Lance R. McMahon and Roger L. Papke
      Molecular Pharmacology October 2020, 98 (4) 328-342; DOI: https://doi.org/10.1124/molpharm.120.000037
    3. Nicotinic Acetylcholine Receptor Accessory Subunits Determine the Activity Profile of Epibatidine Derivatives
      Lu Wenchi Corrie, Clare Stokes, Jenny L. Wilkerson, F. Ivy Carroll, Lance R. McMahon and Roger L. Papke
      Molecular Pharmacology October 2020, 98 (4) 335-349; DOI: https://doi.org/10.1124/molpharm.120.000037

  6. Sugasawa, Yusuke

    1. Enhancement of Muscimol Binding and Gating by Allosteric Modulators of the GABAA Receptor: Relating Occupancy to State Functions
      Gustav Akk, Allison L. Germann, Yusuke Sugasawa, Spencer R. Pierce, Alex S. Evers and Joe Henry Steinbach
      Molecular Pharmacology October 2020, 98 (4) 303-313; DOI: https://doi.org/10.1124/molpharm.120.000066

  7. Sugiarto, Elizabeth

    1. Pain, Motivation, Migraine, and the Microbiome: New Frontiers for Opioid Systems and Disease
      Kyle E. Parker, Elizabeth Sugiarto, Anna M.W. Taylor, Amynah A. Pradhan and Ream Al-Hasani
      Molecular Pharmacology October 2020, 98 (4) 433-444; DOI: https://doi.org/10.1124/mol.120.119438

  8. Szott, S.R.

    1. Spinal Opioid Tolerance Depends upon Platelet-Derived Growth Factor Receptor-β Signaling, Not μ-Opioid Receptor Internalization
      S. Puig, K.E. Barker, S.R. Szott, P.T. Kann, J.S. Morris and H.B. Gutstein
      Molecular Pharmacology October 2020, 98 (4) 487-496; DOI: https://doi.org/10.1124/mol.120.119552

T

  1. Taylor, Anna M.W.

    1. Pain, Motivation, Migraine, and the Microbiome: New Frontiers for Opioid Systems and Disease
      Kyle E. Parker, Elizabeth Sugiarto, Anna M.W. Taylor, Amynah A. Pradhan and Ream Al-Hasani
      Molecular Pharmacology October 2020, 98 (4) 433-444; DOI: https://doi.org/10.1124/mol.120.119438

  2. Thakur, Ganesh A.

    1. Differing Activity Profiles of the Stereoisomers of 2,3,5,6TMP-TQS, a Putative Silent Allosteric Modulator of α7 nAChR
      Roger L. Papke, Sumanta Garai, Clare Stokes, Nicole A. Horenstein, Arthur D. Zimmerman, Khalil A. Abboud and Ganesh A. Thakur
      Molecular Pharmacology October 2020, 98 (4) 292-302; DOI: https://doi.org/10.1124/mol.120.119958

  3. Thatcher, Gregory R.J.

    1. Open Access
      Pharmacology and Molecular Mechanisms of Clinically Relevant Estrogen Estetrol and Estrogen Mimic BMI-135 for the Treatment of Endocrine-Resistant Breast Cancer
      Balkees Abderrahman, Philipp Y. Maximov, Ramona F. Curpan, Jay S. Hanspal, Ping Fan, Rui Xiong, Debra A. Tonetti, Gregory R.J. Thatcher and V. Craig Jordan
      Molecular Pharmacology October 2020, 98 (4) 363-380; DOI: https://doi.org/10.1124/molpharm.120.000054
    2. Open Access
      Pharmacology and Molecular Mechanisms of Clinically Relevant Estrogen Estetrol and Estrogen Mimic BMI-135 for the Treatment of Endocrine-Resistant Breast Cancer
      Balkees Abderrahman, Philipp Y. Maximov, Ramona F. Curpan, Jay S. Hanspal, Ping Fan, Rui Xiong, Debra A. Tonetti, Gregory R.J. Thatcher and V. Craig Jordan
      Molecular Pharmacology October 2020, 98 (4) 364-381; DOI: https://doi.org/10.1124/molpharm.120.000054

  4. Tonetti, Debra A.

    1. Open Access
      Pharmacology and Molecular Mechanisms of Clinically Relevant Estrogen Estetrol and Estrogen Mimic BMI-135 for the Treatment of Endocrine-Resistant Breast Cancer
      Balkees Abderrahman, Philipp Y. Maximov, Ramona F. Curpan, Jay S. Hanspal, Ping Fan, Rui Xiong, Debra A. Tonetti, Gregory R.J. Thatcher and V. Craig Jordan
      Molecular Pharmacology October 2020, 98 (4) 363-380; DOI: https://doi.org/10.1124/molpharm.120.000054
    2. Open Access
      Pharmacology and Molecular Mechanisms of Clinically Relevant Estrogen Estetrol and Estrogen Mimic BMI-135 for the Treatment of Endocrine-Resistant Breast Cancer
      Balkees Abderrahman, Philipp Y. Maximov, Ramona F. Curpan, Jay S. Hanspal, Ping Fan, Rui Xiong, Debra A. Tonetti, Gregory R.J. Thatcher and V. Craig Jordan
      Molecular Pharmacology October 2020, 98 (4) 364-381; DOI: https://doi.org/10.1124/molpharm.120.000054

  5. Tschirhart, Jared N.

    1. Fentanyl-Induced Block of hERG Channels Is Exacerbated by Hypoxia, Hypokalemia, Alkalosis, and the Presence of hERG1b
      Jared N. Tschirhart and Shetuan Zhang
      Molecular Pharmacology October 2020, 98 (4) 508-517; DOI: https://doi.org/10.1124/mol.119.119271

V

  1. Valentino, Rita J.

    1. Opioid Research: Past and Future
      Rita J. Valentino and Nora D. Volkow
      Molecular Pharmacology October 2020, 98 (4) 389-391; DOI: https://doi.org/10.1124/molpharm.120.000093

  2. Veasey, S.C.

    1. Open Access
      Bidirectional Relationship between Opioids and Disrupted Sleep: Putative Mechanisms
      D. Eacret, S.C. Veasey and J.A. Blendy
      Molecular Pharmacology October 2020, 98 (4) 445-453; DOI: https://doi.org/10.1124/mol.119.119107

  3. Volkow, Nora D.

    1. Opioid Research: Past and Future
      Rita J. Valentino and Nora D. Volkow
      Molecular Pharmacology October 2020, 98 (4) 389-391; DOI: https://doi.org/10.1124/molpharm.120.000093

  4. von Zastrow, Mark

    1. Opioid Pharmacology under the Microscope
      Damien Jullié, Arisbel B. Gondin, Mark von Zastrow and Meritxell Canals
      Molecular Pharmacology October 2020, 98 (4) 425-432; DOI: https://doi.org/10.1124/mol.119.119321

W

  1. Wilkerson, Jenny L.

    1. Nicotinic Acetylcholine Receptor Accessory Subunits Determine the Activity Profile of Epibatidine Derivatives
      Lu Wenchi Corrie, Clare Stokes, Jenny L. Wilkerson, F. Ivy Carroll, Lance R. McMahon and Roger L. Papke
      Molecular Pharmacology October 2020, 98 (4) 328-342; DOI: https://doi.org/10.1124/molpharm.120.000037
    2. Nicotinic Acetylcholine Receptor Accessory Subunits Determine the Activity Profile of Epibatidine Derivatives
      Lu Wenchi Corrie, Clare Stokes, Jenny L. Wilkerson, F. Ivy Carroll, Lance R. McMahon and Roger L. Papke
      Molecular Pharmacology October 2020, 98 (4) 335-349; DOI: https://doi.org/10.1124/molpharm.120.000037

  2. Williams, John T.

    1. Chronic Treatment with Morphine Disrupts Acute Kinase-Dependent Desensitization of GPCRs
      Emily R. Leff, Seksiri Arttamangkul and John T. Williams
      Molecular Pharmacology October 2020, 98 (4) 497-507; DOI: https://doi.org/10.1124/mol.119.119362
    2. Open Access
      Recent Progress in Opioid Research from an Electrophysiological Perspective
      William T. Birdsong and John T. Williams
      Molecular Pharmacology October 2020, 98 (4) 401-409; DOI: https://doi.org/10.1124/mol.119.119040

  3. Willing, Benjamin P.

    1. Weak Microbial Metabolites: a Treasure Trove for Using Biomimicry to Discover and Optimize Drugs
      Zdenek Dvorak, Max Klapholz, Thomas P. Burris, Benjamin P. Willing, Antimo Gioiello, Roberto Pellicciari, Francesco Galli, John March, Stephen J. O’Keefe, R. Balfour Sartor, Chang H. Kim, Maayan Levy and Sridhar Mani
      Molecular Pharmacology October 2020, 98 (4) 328-334; DOI: https://doi.org/10.1124/molpharm.120.000035
    2. Weak Microbial Metabolites: a Treasure Trove for Using Biomimicry to Discover and Optimize Drugs
      Zdenek Dvorak, Max Klapholz, Thomas P. Burris, Benjamin P. Willing, Antimo Gioiello, Roberto Pellicciari, Francesco Galli, John March, Stephen J. O’Keefe, R. Balfour Sartor, Chang H. Kim, Maayan Levy and Sridhar Mani
      Molecular Pharmacology October 2020, 98 (4) 343-349; DOI: https://doi.org/10.1124/molpharm.120.000035

  4. Winters, B.L.

    1. Neprilysin Controls the Synaptic Activity of Neuropeptides in the Intercalated Cells of the Amygdala
      G.C. Gregoriou, S.D. Patel, B.L. Winters and E.E. Bagley
      Molecular Pharmacology October 2020, 98 (4) 454-461; DOI: https://doi.org/10.1124/mol.119.119370

X

  1. Xiong, Rui

    1. Open Access
      Pharmacology and Molecular Mechanisms of Clinically Relevant Estrogen Estetrol and Estrogen Mimic BMI-135 for the Treatment of Endocrine-Resistant Breast Cancer
      Balkees Abderrahman, Philipp Y. Maximov, Ramona F. Curpan, Jay S. Hanspal, Ping Fan, Rui Xiong, Debra A. Tonetti, Gregory R.J. Thatcher and V. Craig Jordan
      Molecular Pharmacology October 2020, 98 (4) 363-380; DOI: https://doi.org/10.1124/molpharm.120.000054
    2. Open Access
      Pharmacology and Molecular Mechanisms of Clinically Relevant Estrogen Estetrol and Estrogen Mimic BMI-135 for the Treatment of Endocrine-Resistant Breast Cancer
      Balkees Abderrahman, Philipp Y. Maximov, Ramona F. Curpan, Jay S. Hanspal, Ping Fan, Rui Xiong, Debra A. Tonetti, Gregory R.J. Thatcher and V. Craig Jordan
      Molecular Pharmacology October 2020, 98 (4) 364-381; DOI: https://doi.org/10.1124/molpharm.120.000054

  2. Xu, Jin

    1. A Truncated Six Transmembrane Splice Variant MOR-1G Enhances Expression of the Full-Length Seven Transmembrane μ-Opioid Receptor through Heterodimerization
      Tiffany Zhang, Jin Xu and Ying-Xian Pan
      Molecular Pharmacology October 2020, 98 (4) 518-527; DOI: https://doi.org/10.1124/mol.120.119453

Z

  1. Zhang, Rui

    1. Dietary Caffeine Synergizes Adverse Peripheral and Central Responses to Anesthesia in Malignant Hyperthermia Susceptible Mice
      Monica Aleman, Rui Zhang, Wei Feng, Lihong Qi, Jose R. Lopez, Chelsea Crowe, Yao Dong, Genady Cherednichenko and Isaac N. Pessah
      Molecular Pharmacology October 2020, 98 (4) 351-363; DOI: https://doi.org/10.1124/mol.120.119412

  2. Zhang, Shetuan

    1. Fentanyl-Induced Block of hERG Channels Is Exacerbated by Hypoxia, Hypokalemia, Alkalosis, and the Presence of hERG1b
      Jared N. Tschirhart and Shetuan Zhang
      Molecular Pharmacology October 2020, 98 (4) 508-517; DOI: https://doi.org/10.1124/mol.119.119271

  3. Zhang, Tiffany

    1. A Truncated Six Transmembrane Splice Variant MOR-1G Enhances Expression of the Full-Length Seven Transmembrane μ-Opioid Receptor through Heterodimerization
      Tiffany Zhang, Jin Xu and Ying-Xian Pan
      Molecular Pharmacology October 2020, 98 (4) 518-527; DOI: https://doi.org/10.1124/mol.120.119453

  4. Zimmerman, Arthur D.

    1. Differing Activity Profiles of the Stereoisomers of 2,3,5,6TMP-TQS, a Putative Silent Allosteric Modulator of α7 nAChR
      Roger L. Papke, Sumanta Garai, Clare Stokes, Nicole A. Horenstein, Arthur D. Zimmerman, Khalil A. Abboud and Ganesh A. Thakur
      Molecular Pharmacology October 2020, 98 (4) 292-302; DOI: https://doi.org/10.1124/mol.120.119958
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