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Molecular Pharmacology

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Table of Contents

December 01, 2020; Volume 98,Issue 6

Special Section on RGS Proteins in Health and Disease

  • You have access
    RGS Proteins as Critical Regulators of Motor Function and Their Implications in Parkinson’s Disease
    Katelin E. Ahlers-Dannen, Mackenzie M. Spicer and Rory A. Fisher
    Molecular Pharmacology December 2020, 98 (6) 730-738; DOI: https://doi.org/10.1124/mol.119.118836
  • You have access
    Regulators of G Protein Signaling in Analgesia and Addiction
    Farhana Sakloth, Claire Polizu, Feodora Bertherat and Venetia Zachariou
    Molecular Pharmacology December 2020, 98 (6) 739-750; DOI: https://doi.org/10.1124/mol.119.119206
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    Emerging Roles for Regulator of G Protein Signaling 2 in (Patho)physiology
    Harrison J. McNabb, Qian Zhang and Benita Sjögren
    Molecular Pharmacology December 2020, 98 (6) 751-760; DOI: https://doi.org/10.1124/molpharm.120.000111

Accelerated Communication

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    Reduced Activation of the Synaptic-Type GABAA Receptor Following Prolonged Exposure to Low Concentrations of Agonists: Relationship between Tonic Activity and Desensitization
    Spencer R. Pierce, Allison L. Germann, Alex S. Evers, Joe Henry Steinbach and Gustav Akk
    Molecular Pharmacology December 2020, 98 (6) 762-769; DOI: https://doi.org/10.1124/molpharm.120.000088

Articles

  • Structure of the Complex of an Iminopyridinedione Protein Tyrosine Phosphatase 4A3 Phosphatase Inhibitor with Human Serum Albumin
    You have access
    Structure of the Complex of an Iminopyridinedione Protein Tyrosine Phosphatase 4A3 Phosphatase Inhibitor with Human Serum Albumin
    Mateusz P. Czub, Adam M. Boulton, Ettore J. Rastelli, Nikhil R. Tasker, Taber S. Maskrey, Isabella K. Blanco, Kelley E. McQueeney, John H. Bushweller, Wladek Minor, Peter Wipf, Elizabeth R. Sharlow and John S. Lazo
    Molecular Pharmacology December 2020, 98 (6) 648-657; DOI: https://doi.org/10.1124/molpharm.120.000131
  • You have access
    The Influence of Tobacco Smoke/Nicotine on CYP2A Expression in Human and African Green Monkey Lungs
    Yuan Gao, Sharon Miksys, Roberta M. Palmour and Rachel F. Tyndale
    Molecular Pharmacology December 2020, 98 (6) 658-668; DOI: https://doi.org/10.1124/molpharm.120.000100
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    GZD824 Inhibits GCN2 and Sensitizes Cancer Cells to Amino Acid Starvation Stress
    Yu Kato, Kazuhiro Kunimasa, Mizuki Takahashi, Ayaka Harada, Ikuko Nagasawa, Masanori Osawa, Yoshikazu Sugimoto and Akihiro Tomida
    Molecular Pharmacology December 2020, 98 (6) 669-676; DOI: https://doi.org/10.1124/molpharm.120.000070
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    N-Terminal Targeting of Regulator of G Protein Signaling Protein 2 for F-Box Only Protein 44–Mediated Proteasomal Degradation
    Harrison J. McNabb, Stephanie Gonzalez, Christine S. Muli and Benita Sjögren
    Molecular Pharmacology December 2020, 98 (6) 677-685; DOI: https://doi.org/10.1124/molpharm.120.000061
  • MicroRNA-1291-5p Sensitizes Pancreatic Carcinoma Cells to Arginine Deprivation and Chemotherapy through the Regulation of Arginolysis and Glycolysis
    Open Access
    MicroRNA-1291-5p Sensitizes Pancreatic Carcinoma Cells to Arginine Deprivation and Chemotherapy through the Regulation of Arginolysis and Glycolysis
    Mei-Juan Tu, Zhijian Duan, Zhenzhen Liu, Chao Zhang, Richard J. Bold, Frank J. Gonzalez, Edward J. Kim and Ai-Ming Yu
    Molecular Pharmacology December 2020, 98 (6) 686-694; DOI: https://doi.org/10.1124/molpharm.120.000130
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    Allosterically Potentiated α7 Nicotinic Acetylcholine Receptors: Reduced Calcium Permeability and Current-Independent Control of Intracellular Calcium
    Douglas R. Miller, Habibeh Khoshbouei, Sumanta Garai, Lucas N. Cantwell, Clare Stokes, Ganesh Thakur and Roger L. Papke
    Molecular Pharmacology December 2020, 98 (6) 695-709; DOI: https://doi.org/10.1124/molpharm.120.000012
  • Arginine-259 of UGT2B7 Confers UDP-Sugar Selectivity
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    Arginine-259 of UGT2B7 Confers UDP-Sugar Selectivity
    Pramod C. Nair, Nuy Chau, Ross A. McKinnon and John O. Miners
    Molecular Pharmacology December 2020, 98 (6) 710-718; DOI: https://doi.org/10.1124/molpharm.120.000104
  • Open Access
    Glutamate, d-(−)-2-Amino-5-Phosphonopentanoic Acid, and N-Methyl-d-Aspartate Do Not Directly Modulate Glycine Receptors
    Karin R. Aubrey, Diba Sheipouri, Thomas Balle, Robert J. Vandenberg and Yo Otsu
    Molecular Pharmacology December 2020, 98 (6) 719-729; DOI: https://doi.org/10.1124/molpharm.120.000127
  • Domain-Swap Dimerization of <em>Acanthamoeba castellanii</em> CYP51 and a Unique Mechanism of Inactivation by Isavuconazole
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    Domain-Swap Dimerization of Acanthamoeba castellanii CYP51 and a Unique Mechanism of Inactivation by Isavuconazole
    Vandna Sharma, Brian Shing, Lilian Hernandez-Alvarez, Anjan Debnath and Larissa M. Podust
    Molecular Pharmacology December 2020, 98 (6) 770-780; DOI: https://doi.org/10.1124/molpharm.120.000092

Corrections

  • You have access
    Correction to “Insulin-Like Growth Factor-1 Receptor Signaling Increases the Invasive Potential of Human Epidermal Growth Factor Receptor 2–Overexpressing Breast Cancer Cells via Src-Focal Adhesion Kinase and Forkhead Box Protein M1”
    Molecular Pharmacology December 2020, 98 (6) 761; DOI: https://doi.org/10.1124/mol.114.095380err
  • You have access
    Correction to “Structure of the Complex of an Iminopyridinedione Protein Tyrosine Phosphatase 4A3 Phosphatase Inhibitor with Human Serum Albumin”
    Molecular Pharmacology December 2020, 98 (6) 781; DOI: https://doi.org/10.1124/molpharm.120.000131err
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In this issue

Molecular Pharmacology: 98 (6)
Molecular Pharmacology
Vol. 98, Issue 6
1 Dec 2020
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
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  • Editorial Board (PDF)
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  • Special Section on RGS Proteins in Health and Disease
  • Accelerated Communication
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  • SB-431542 Is a Potent and Specific Inhibitor of Transforming Growth Factor-β Superfamily Type I Activin Receptor-Like Kinase (ALK) Receptors ALK4, ALK5, and ALK7
  • The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints
  • Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases
  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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