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Molecular Pharmacology

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Table of Contents

April 01, 2021; Volume 99,Issue 4

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    Arrestin-Dependent and -Independent Internalization of G Protein–Coupled Receptors: Methods, Mechanisms, and Implications on Cell Signaling
    Ee Von Moo, Jeffrey R. van Senten, Hans Bräuner-Osborne and Thor C. Møller
    Molecular Pharmacology April 2021, 99 (4) 242-255; DOI: https://doi.org/10.1124/molpharm.120.000192
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    The Emerging Role of Neuronal Organoid Models in Drug Discovery: Potential Applications and Hurdles to Implementation
    Laura A. Struzyna and Marla L. Watt
    Molecular Pharmacology April 2021, 99 (4) 256-265; DOI: https://doi.org/10.1124/molpharm.120.000142

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    Mechanism-Based Inactivation of Cytochrome P450 3A4 by Benzbromarone
    Lloyd Wei Tat Tang, Ravi Kumar Verma, Hao Fan and Eric Chun Yong Chan
    Molecular Pharmacology April 2021, 99 (4) 266-276; DOI: https://doi.org/10.1124/molpharm.120.000086
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    A Potential Role for SerpinA3N in Acetaminophen-Induced Hepatotoxicity
    Melanie Tran, Jianguo Wu, Li Wang and Dong-Ju Shin
    Molecular Pharmacology April 2021, 99 (4) 277-285; DOI: https://doi.org/10.1124/molpharm.120.000117
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    Chronic Exposure to SCO-267, an Allosteric GPR40 Full Agonist, Is Effective in Improving Glycemic Control in Rats
    Ryokichi Koyama, Mitsugi Ookawara, Masanori Watanabe and Yusuke Moritoh
    Molecular Pharmacology April 2021, 99 (4) 286-293; DOI: https://doi.org/10.1124/molpharm.120.000168
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    Elevated cAMP Protects against Diclofenac-Induced Toxicity in Primary Rat Hepatocytes: A Protective Effect Mediated by the Exchange Protein Directly Activated by cAMP/cAMP-Regulated Guanine Nucleotide Exchange Factors
    Fabio Alejandro Aguilar Mora, Nshunge Musheshe, Asmaa Oun, Manon Buist-Homan, Frank Lezoualc’h, Xiaodong Cheng, Martina Schmidt and Han Moshage
    Molecular Pharmacology April 2021, 99 (4) 294-307; DOI: https://doi.org/10.1124/molpharm.120.000217
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Molecular Pharmacology: 99 (4)
Molecular Pharmacology
Vol. 99, Issue 4
1 Apr 2021
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  • SB-431542 Is a Potent and Specific Inhibitor of Transforming Growth Factor-β Superfamily Type I Activin Receptor-Like Kinase (ALK) Receptors ALK4, ALK5, and ALK7
  • The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints
  • Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases
  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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